References

A polarity pathway for exocyst-dependent intracellular tube extension

10.7554/elife.65169 · 2021 · External reference

C. elegans bicd-1, homolog of the Drosophila dynein accessory factor Bicaudal D, regulates the branching of PVD sensory neuron dendrites

10.1242/dev.060939 · 2011 · External reference

The RAL signaling network: Cancer and beyond

10.1016/bs.ircmb.2020.10.005 · 2021 · External reference

Polarized exocyst-mediated vesicle fusion directs intracellular lumenogenesis within the C. elegans excretory cell

10.1016/j.ydbio.2014.07.019 · 2014 · External reference

Repurposing an endogenous degradation system for rapid and targeted depletion of C. elegans proteins

10.1242/dev.115048 · 2014 · External reference

Efficient marker-free recovery of custom genetic modifications with CRISPR/Cas9 in Caenorhabditis elegans

10.1534/genetics.114.169730 · 2014 · External reference

Friends and foes in synaptic transmission: The role of tomosyn in vesicle priming

10.1016/j.tins.2009.01.004 · 2009 · External reference

An expanded auxin-inducible degron toolkit for Caenorhabditis elegans

10.1093/genetics/iyab006 · 2021 · External reference

Ordering gene function: The interpretation of epistasis in regulatory hierarchies

10.1016/0168-9525(92)90263-4 · 1992 · External reference

The Ral/exocyst effector complex counters c-Jun N-terminal kinase-dependent apoptosis in Drosophila melanogaster

10.1128/mcb.00506-06 · 2006 · External reference

Review series: Rab GTPases and membrane identity: causal or inconsequential?

10.1083/jcb.201306010 · 2013 · External reference

RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly

10.1016/j.cell.2010.12.018 · 2011 · External reference

The brain exocyst complex interacts with RalA in a GTP-dependent manner: Identification of a novel mammalian Sec3 gene and a second Sec15 gene

10.1074/jbc.c100320200 · 2001 · External reference

RAS GTPase-dependent pathways in developmental diseases: Old guys, new lads, and current challenges.

10.1016/j.ceb.2018.06.007 · 2018 · External reference

Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases

10.1128/mcb.15.8.4578 · 1995 · External reference

large-scale screening for targeted knockouts in the Caenorhabditis elegans genome

10.1534/g3.112.003830 · 2012 · External reference

RAB-10 is required for endocytic recycling in the Caenorhabditis elegans intestine

10.1091/mbc.e05-08-0787 · 2006 · External reference

RALGAPA1 deletion in Belgian shepherd dogs with Cerebellar Ataxia

10.3390/genes14081520 · 2023 · External reference

Drugging the undruggable RAS: Mission possible?

10.1038/nrd4389 · 2014 · External reference

A simple strategy for addition of degron tags to endogenous genes harboring prior insertions of fluorescent protein

10.17912/micropub.biology.000622 · 2022 · External reference

RAP-2 and CNH-MAP4 Kinase MIG-15 confer resistance in bystander epithelium to cell-fate transformation by excess Ras or notch activity

10.1073/pnas.2414321121 · 2025 · External reference

Dramatic enhancement of genome editing by CRISPR/Cas9 through improved guide RNA design

10.1534/genetics.115.175166 · 2015 · External reference

Tools of the trade: Use of dominant-inhibitory mutants of Ras-family GTPases

10.1038/10018 · 1999 · External reference

Ral-GTPases: Approaching their 15 minutes of fame

10.1016/s0962-8924(03)00152-1 · 2003 · External reference

RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans

10.1038/sj.emboj.7601922 · 2007 · External reference

Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex

10.1093/emboj/cdg329 · 2003 · External reference

Ral small GTPase signaling and oncogenesis: More than just 15minutes of fame

10.1016/j.bbamcr.2014.09.004 · 2014 · External reference

Microinjection for precision genome editing in Caenorhabditis elegans

10.1016/j.xpro.2021.100748 · 2021 · External reference

Melting dsDNA donor molecules greatly improves precision genome editing in Caenorhabditis elegans

10.1534/genetics.120.303564 · 2020 · External reference

Emerging treatments in lung cancer - Targeting the RLIP76 molecular transporter

10.2147/lctt.s53672 · 2013 · External reference

Sequential gene function in the initiation of Saccharomyces cerevisiae DNA synthesis

10.1016/0022-2836(74)90451-3 · 1974 · External reference

De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay

10.1371/journal.pgen.1007671 · 2018 · External reference

Subunit composition, protein interactions, and structures of the mammalian brain sec6/8 complex and septin filaments

10.1016/s0896-6273(00)80493-6 · 1998 · External reference

The mammalian brain rsec6/8 complex

10.1016/s0896-6273(00)80251-2 · 1996 · External reference

RAL-1 controls multivesicular body biogenesis and exosome secretion

10.1083/jcb.201504136 · 2015 · External reference

Lessons from worm dendritic patterning

10.1146/annurev-neuro-072116-031437 · 2019 · External reference

Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase

10.1038/sj.emboj.7600699 · 2005 · External reference

Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity

10.1074/jbc.270.38.22473 · 1995 · External reference

Germline transformation of Caenorhabditis elegans by injection

10.1007/978-1-59745-202-1_10 · 2009 · External reference

Ral GTPases in tumorigenesis: Emerging from the shadows

10.1016/j.yexcr.2013.06.020 · 2013 · External reference

Exposing the elusive exocyst structure.

10.1016/j.tibs.2018.06.012 · 2018 · External reference

A model for RAS mutation patterns in cancers: finding the sweet spot.

10.1038/s41568-018-0076-6 · 2018 · External reference

Parallel Rap1>RalGEF>Ral and Ras signals sculpt the C. elegans nervous system

10.1016/j.ydbio.2021.05.004 · 2021 · External reference

Author Correction: Cryo-EM structure of the exocyst complex

10.1038/s41594-018-0157-y · 2018 · External reference

Cryo-EM structure of the exocyst complex

10.1038/s41594-017-0016-2 · 2018 · External reference

Allosteric regulation of exocyst: Discrete activation of tethering by two spatial signals

10.1083/jcb.202206108 · 2023 · External reference

ColabFold: Making protein folding accessible to all

10.1038/s41592-022-01488-1 · 2022 · External reference

The exocyst is a Ral effector complex

10.1038/ncb728 · 2002 · External reference

Ral GTPases regulate exocyst assembly through dual subunit interactions

10.1074/jbc.m308702200 · 2003 · External reference

Mutations in the exocyst component Sec5 disrupt neuronal membrane traffic, but neurotransmitter release persists

10.1016/s0896-6273(03)00031-x · 2003 · External reference

Sec6 mutations and the Drosophila exocyst complex

10.1242/jcs.01644 · 2005 · External reference

The exocyst component Sec5 is required for membrane traffic and polarity in the Drosophila ovary

10.1242/dev.00931 · 2004 · External reference

The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector

10.1128/mcb.06291-11 · 2012 · External reference

A putative effector of Ral has homology to Rho/Rac GTPase activating proteins

1995 · External reference

The exocyst complex is an essential component of the mammalian constitutive secretory pathway

10.1083/jcb.202205137 · 2023 · External reference

Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis

10.1016/j.cub.2012.09.013 · 2012 · External reference

The In vivo architecture of the exocyst provides structural basis for exocytosis

10.1016/j.cell.2017.01.004 · 2017 · External reference

The frequency of ras mutations in cancer

10.1158/0008-5472.can-19-3682 · 2020 · External reference

Small GTPases

10.1895/wormbook.1.67.2 · 2018 · External reference

Syndapin and GTPase RAP-1 control endocytic recycling via RHO-1 and non-muscle myosin II

10.1016/j.cub.2023.09.051 · 2023 · External reference

Homology and modular evolution of CATCHR at the origin of the eukaryotic endomembrane system

10.1093/gbe/evab125 · 2021 · External reference

Genetic and biochemical analysis of vesicular traffic in yeast

10.1016/0955-0674(92)90076-o · 1992 · External reference

EHBP-1 functions with RAB-10 during endocytic recycling in Caenorhabditis elegans

10.1091/mbc.e10-02-0149 · 2010 · External reference

TULIP1 (RALGAPA1) haploinsufficiency with brain development delay

10.1016/j.ygeno.2009.08.015 · 2009 · External reference

Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals

10.1371/journal.pgen.1008056 · 2019 · External reference

Ral signals through a MAP4 Kinase-p38 MAP kinase Cascade in C. elegans cell fate patterning

10.1016/j.celrep.2018.08.011 · 2018 · External reference

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase

10.1016/0092-8674(91)90065-7 · 1991 · External reference

An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro

10.1016/0092-8674(93)90169-q · 1993 · External reference

Direct trafficking pathways from the Golgi apparatus to the plasma membrane

10.1016/j.semcdb.2020.04.001 · 2020 · External reference

RAS, wanted dead or alive: Advances in targeting RAS mutant cancers

10.1126/scisignal.aay6013 · 2020 · External reference

WormBase 2024: Status and transitioning to Alliance infrastructure

10.1093/genetics/iyae050 · 2024 · External reference

The exocyst complex binds the small GTPase RalA to mediate filopodia formation

10.1038/ncb720 · 2002 · External reference

The Caenorhabditis elegans cuticle and precuticle: A model for studying dynamic apical extracellular matrices in vivo

10.1093/genetics/iyae072 · 2024 · External reference

Mechanisms that regulate morphogenesis of a highly branched neuron in C. elegans

10.1016/j.ydbio.2019.04.002 · 2019 · External reference

Membrane tethers at a glance

10.1242/jcs.260471 · 2023 · External reference

RAB-10 regulates dendritic branching by balancing dendritic transport

10.1371/journal.pgen.1005695 · 2015 · External reference

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

10.1016/s0378-1119(00)00579-5 · 2001 · External reference

Regulation of yeast polarized exocytosis by phosphoinositide lipids

10.1007/s00018-024-05483-x · 2024 · External reference

Bi-allelic variants in RALGAPA1 cause profound neurodevelopmental disability, muscular Hypotonia, infantile spasms, and feeding abnormalities

10.1016/j.ajhg.2020.01.002 · 2020 · External reference

An efficient genome editing strategy to generate putative null mutants in Caenorhabditis elegans using CRISPR/Cas9

10.1534/g3.118.200662 · 2018 · External reference

RalA-exocyst interaction mediates GTP-dependent exocytosis

10.1074/jbc.m400522200 · 2004 · External reference

Identification and characterization of essential genes in the human genome

10.1126/science.aac7041 · 2015 · External reference

Genetic screens in human cells using the CRISPR-Cas9 system

10.1126/science.1246981 · 2014 · External reference

The Ras superfamily at a glance

10.1242/jcs.01660 · 2005 · External reference

The exocyst at a glance

10.1242/jcs.156398 · 2015 · External reference

The ghost in the machine: Small GTPases as spatial regulators of exocytosis

10.1016/j.tcb.2008.06.007 · 2008 · External reference

Brain somatic variant in ras-like small GTPase RALA causes focal cortical dysplasia type II

10.3389/fnbeh.2022.919485 · 2022 · External reference

Structural extension of the human exocyst is enabled by a minimal interface

10.1016/j.str.2026.02.004 · 2026 · External reference

Beyond being innervated: The epidermis actively shapes sensory dendritic patterning

10.1098/rsob.180257 · 2019 · External reference

Differential effector engagement by oncogenic KRAS

10.1016/j.celrep.2018.01.051 · 2018 · External reference

Ras effector switching promotes divergent cell fates in C. elegans vulval patterning

10.1016/j.devcel.2010.12.004 · 2011 · External reference

The auxin-inducible degradation (AID) system enables versatile conditional protein depletion in C. elegans

10.1242/dev.129635 · 2015 · External reference

SAX-7 and menorin light the path for dendrite morphogenesis

10.1016/j.cell.2013.09.029 · 2013 · External reference

RAB-10-dependent membrane transport is required for dendrite arborization

10.1371/journal.pgen.1005484 · 2015 · External reference