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References from A structural model for the autoinhibition of the γ-TuRC–activating CM1 domain. Local targets link to admitted publications; unresolved targets remain external evidence.
Structure of the γ-tubulin ring complex-capped microtubule
10.1038/s41594-024-01264-z · 2024 · External reference
Transition of human γ-tubulin ring complex into a closed conformation during microtubule nucleation
10.1126/science.adk6160 · 2024 · External reference
Microtubule dynamics: An interplay of biochemistry and mechanics
10.1038/s41580-018-0009-y · 2018 · External reference
CDK5RAP2 stimulates microtubule nucleation by the γ-tubulin ring complex
10.1083/jcb.201007030 · 2010 · External reference
The centrosome-specific phosphorylation of Cnn by Polo/Plk1 drives Cnn scaffold assembly and centrosome maturation
10.1016/j.devcel.2014.02.013 · 2014 · External reference
Microtubule nucleation properties of single human γTuRCs explained by their Cryo-EM structure
10.1016/j.devcel.2020.04.019 · 2020 · External reference
MZT1 regulates microtubule nucleation by linking γTuRC assembly to adapter-mediated targeting and activation
10.1242/jcs.195321 · 2017 · External reference
Sampling alternative conformational states of transporters and receptors with AlphaFold2
10.7554/elife.75751 · 2022 · External reference
Structure of the native γ-tubulin ring complex capping spindle microtubules
10.1038/s41594-024-01281-y · 2024 · External reference
Coot: Model-building tools for molecular graphics
10.1107/s0907444904019158 · 2004 · External reference
DADIMODO: A program for refining the structure of multidomain proteins and complexes against small-angle scattering data and NMR-derived restraints
10.1107/s0021889811035758 · 2011 · External reference
Assembly and regulation of γ-tubulin complexes
10.1098/rsob.170266 · 2018 · External reference
CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex
10.1091/mbc.e07-04-0371 · 2008 · External reference
FOXTROT: A JAVA-based application to reduce and analyse SAXS and waxs piles of 2D data at synchrotron soleil
2026 · External reference
PLK1-dependent activation of LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2
10.1038/ncb3204 · 2015 · External reference
The Drosophila homeotic target gene centrosomin (cnn) encodes a novel centrosomal protein with leucine zippers and maps to a genomic region required for midgut morphogenesis
10.1242/dev.121.11.3861 · 1995 · External reference
BioXTAS RAW 2: New developments for a free open-source program for small-angle scattering data reduction and analysis
10.1107/s1600576723011019 · 2024 · External reference
MAFFT multiple sequence alignment software version 7: Improvements in performance and usability
10.1093/molbev/mst010 · 2013 · External reference
Microtubule nucleation by γ-tubulin complexes
10.1038/nrm3209 · 2011 · External reference
Targeting of γ-tubulin complexes to microtubule organizing centers: Conservation and divergence
10.1016/j.tcb.2014.12.002 · 2014 · External reference
Insights into the assembly and activation of the microtubule nucleator γ-TuRC
10.1038/s41586-019-1896-6 · 2019 · External reference
Activation of the γ-Tubulin complex by the Mto1/2 complex
10.1016/j.cub.2014.03.006 · 2014 · External reference
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
10.1038/s41592-019-0459-y · 2019 · External reference
UCSF ChimeraX: Tools for structure building and analysis
10.1002/pro.4792 · 2023 · External reference
ColabFold: Making protein folding accessible to all
10.1038/s41592-022-01488-1 · 2022 · External reference
Divergent regulation of functionally distinct γ-tubulin complexes during differentiation
10.1083/jcb.201601099 · 2016 · External reference
Phosphorylation remodels the mitotic centrosome matrix to generate bipartite γ-tubulin complex docking sites
10.1126/sciadv.aed6539 · 2026 · External reference
Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome
10.1083/jcb.202009083 · 2021 · External reference
The PRIDE database resources in 2022: A hub for mass spectrometry-based proteomics evidences
10.1093/nar/gkab1038 · 2021 · External reference
Simple and fast maximally deuterated control (maxD) preparation for hydrogen–deuterium exchange mass spectrometry experiments
10.1021/acs.analchem.2c01446 · 2022 · External reference
The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC)
10.7554/elife.80053 · 2022 · External reference
HHblits: Lightning-fast iterative protein sequence searching by HMM-HMM alignment
10.1038/nmeth.1818 · 2012 · External reference
Evolutionary refinement of the 3D structure of multi-domain protein complexes from small angle X-ray scattering data
10.1145/3319619.3322002 · 2019 · External reference
Structural basis of human γTuRC closure during CM1-activated microtubule nucleation
10.1038/s41467-026-70773-w · 2026 · External reference
CDK5RAP2 activates microtubule nucleator γTuRC by facilitating template formation and actin release
10.1016/j.devcel.2024.09.001 · 2024 · External reference
MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets
10.1038/nbt.3988 · 2017 · External reference
Sequence-specific random coil chemical shifts of intrinsically disordered proteins
10.1021/ja105656t · 2010 · External reference
BioSAXS on the SWING beamline at synchrotron SOLEIL
10.1107/s1600576721008736 · 2021 · External reference
Microtubule nucleation by γ-tubulin complexes and beyond
10.1042/ebc20180028 · 2018 · External reference
Autoinhibition of Cnn binding to γ-TuRCs prevents ectopic microtubule nucleation and cell division defects
10.1083/jcb.202010020 · 2021 · External reference
γ-TuRC heterogeneity revealed by analysis of Mozart1
10.1016/j.cub.2018.05.044 · 2018 · External reference
γ-TuRC asymmetry induces local protofilament mismatch at the RanGTP-stimulated microtubule minus end
10.1038/s44318-024-00087-4 · 2024 · External reference
Predicting multiple conformations via sequence clustering and AlphaFold2
10.1038/s41586-023-06832-9 · 2024 · External reference
Asymmetric molecular architecture of the human γ-Tubulin ring complex
10.1016/j.cell.2019.12.007 · 2019 · External reference
1H, 13C and 15N chemical shift referencing in biomolecular NMR
10.1007/bf00211777 · 1995 · External reference
Partial closure of the γ-tubulin ring complex by CDK5RAP2 activates microtubule nucleation
10.1016/j.devcel.2024.09.002 · 2024 · External reference
Autoinhibitory mechanism controls binding of centrosomin motif 1 to γ-tubulin ring complex
10.1083/jcb.202007101 · 2023 · External reference
Proper recruitment of gamma-tubulin and D-TACC/Msps to embryonic Drosophila centrosomes requires Centrosomin motif 1
10.1091/mbc.e07-05-0474 · 2007 · External reference
Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes
10.1083/jcb.202212043 · 2023 · External reference
Assembly of the asymmetric human γ-tubulin ring complex by RUVBL1-RUVBL2 AAA ATPase
10.1126/sciadv.abe0894 · 2020 · External reference
