Research graph
References from Manganese dioxide nanoparticles attenuate pathological retinal angiogenesis by inhibiting the PLK1/AKT/FOXO1 signaling axis. Local targets link to admitted publications; unresolved targets remain external evidence.
Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy
10.1126/science.aay5356 · 2020 · External reference
Pathophysiology and mechanisms of severe retinopathy of prematurity
10.1016/j.ophtha.2014.07.050 · 2015 · External reference
Diabetic retinopathy
10.1038/nrdp.2016.12 · 2016 · External reference
Diabetic retinopathy
10.1016/s0140-6736(09)62124-3 · 2010 · External reference
Retinal and choroidal vascular diseases: past, present, and future: the 2021 proctor lecture
10.1167/iovs.62.14.26 · 2021 · External reference
Retinal angiomatous proliferation
10.1016/j.survophthal.2017.01.008 · 2017 · External reference
Incomplete response to anti-VEGF therapy in neovascular AMD: exploring disease mechanisms and therapeutic opportunities
10.1016/j.preteyeres.2020.100906 · 2021 · External reference
Correction: diabetic retinopathy and diabetic macular oedema pathways and management: UK consensus working group
10.1038/s41433-020-1087-6 · 2020 · External reference
Persistent macular thickening after ranibizumab treatment for diabetic macular edema with vision Impairment
10.1001/jamaophthalmol.2015.5346 · 2016 · External reference
Early and long-term responses to anti-vascular endothelial growth factor therapy in diabetic macular edema: analysis of Protocol I data
10.1016/j.ajo.2016.09.012 · 2016 · External reference
Persistence of retinal fluid after anti-VEGF treatment for neovascular age-related macular degeneration: a systematic review and meta-analysis
10.1016/j.oret.2025.01.010 · 2025 · External reference
One-year outcomes of Aflibercept for refractory diabetic macular edema in Bevacizumab nonresponders
10.4103/ijo.ijo_459_20 · 2021 · External reference
Efficacy of every four monthly and quarterly dosing of faricimab vs ranibizumab in neovascular age-related macular degeneration: the STAIRWAY Phase 2 randomized clinical trial
10.1001/jamaophthalmol.2020.2699 · 2020 · External reference
Dexamethasone intravitreal implant in diabetic macular oedema refractory to anti-vascular endothelial growth factors: the AUSSIEDEX study
10.1136/bmjophth-2022-001224 · 2023 · External reference
Timing of switching to steroid implants in cases of recalcitrant diabetic macular edema not responding to anti-vascular endothelial growth factor (VEGF) therapy: a real-world study
10.7759/cureus.62385 · 2024 · External reference
Factors affecting intensive aflibercept treatment response in diabetic macular edema: a real-world study
10.1155/2023/1485059 · 2023 · External reference
Baseline visual acuity strongly predicts visual acuity gain in patients with diabetic macular edema following anti-vascular endothelial growth factor treatment across trials
10.2147/opth.s100764 · 2016 · External reference
Good initial visual acuity in patients with macular edema due to retinal vein occlusion: management and outcomes
10.1097/iae.0000000000004244 · 2024 · External reference
Efficacy and safety of dexamethasone versus intravitreal aflibercept implants for macular edema: a systematic review and meta-analysis
10.1186/s40001-025-02404-x · 2025 · External reference
Diabetic retinopathy
10.1056/nejmra1005073 · 2012 · External reference
Panretinal photocoagulation vs intravitreous ranibizumab for proliferative diabetic retinopathy: a randomized clinical trial
10.1001/jama.2015.15217 · 2015 · External reference
Molecular pathogenesis of retinal and choroidal vascular diseases
10.1016/j.preteyeres.2015.06.002 · 2015 · External reference
Tracking real-world persistence and adherence to anti-VEGF intravitreal therapy with prefilled syringes: a German prescription sales analysis
10.1136/bmjophth-2025-002334 · 2025 · External reference
Screening for diabetic retinopathy: new perspectives and challenges
10.1016/s2213-8587(19)30411-5 · 2020 · External reference
A real-world study for timely assessing the diabetic macular edema refractory to intravitreal anti-VEGF treatment
10.3389/fendo.2023.1108097 · 2023 · External reference
Short-term response to anti-VEGF as indicator of visual prognosis in refractory age-related macular degeneration
10.1038/s41433-023-02900-6 · 2024 · External reference
A systematic review of the adverse events of intravitreal anti-vascular endothelial growth factor injections
10.1097/iae.0b013e3182278ab4 · 2011 · External reference
Clinical Efficacy of switching to faricimab in treatment resistant neovascular age-related macular degeneration: systematic review and meta-analysis
10.1016/j.ajo.2025.08.034 · 2025 · External reference
Manganese dioxide nanosheets: from preparation to biomedical applications
10.2147/ijn.s207666 · 2019 · External reference
Copper oxide nanoparticles suppress retinal angiogenesis via inducing endothelial cell cuproptosis
10.2217/nnm-2023-0301 · 2024 · External reference
Copper oxide nanoparticles: in vitro and in vivo toxicity, mechanisms of action and factors influencing their toxicology
10.1016/j.cbpc.2023.109682 · 2023 · External reference
Enzymatically synthesised MnO(2) nanoparticles for efficient near-infrared photothermal therapy and dual-responsive magnetic resonance imaging
10.1039/d1nr02400k · 2021 · External reference
MnO(2)-Based nanosystems for cancer therapy
10.1039/d0cc02782k · 2020 · External reference
Manganese dioxide nanoparticle induces Parkinson like neurobehavioral abnormalities in rats
10.4149/bll_2018_070 · 2018 · External reference
Author correction: transcriptomics-based investigation of manganese dioxide nanoparticle toxicity in rats’ choroid plexus
10.1038/s41598-024-59889-5 · 2024 · External reference
Fucoidan-manganese dioxide nanoparticles potentiate radiation therapy by co-targeting tumor hypoxia and angiogenesis
10.3390/md16120510 · 2018 · External reference
Spatiotemporally controlled co-treatment of lung cancer and pulmonary immune-related adverse events by inhalable albumin-chaperoned ultrathin MnO(2) nanosheets
10.1021/acsnano.5c01888 · 2025 · External reference
Gelation embolism agents suppress clinical TACE-incited pro-metastatic microenvironment against hepatocellular carcinoma progression
10.1016/j.ebiom.2024.105436 · 2024 · External reference
The role of polo-like Kinase 1 in regulating the forkhead box family transcription factors
10.3390/cells12091344 · 2023 · External reference
Onvansertib in combination with chemotherapy and bevacizumab in second-line treatment of KRAS-mutant metastatic colorectal cancer: a single-arm, Phase II trial
10.1200/jco-24-01266 · 2025 · External reference
Pristimerin synergistically sensitizes conditionally reprogrammed patient derived-primary hepatocellular carcinoma cells to sorafenib through endoplasmic reticulum stress and ROS generation by modulating Akt/FoxO1/p27(kip1) signaling pathway
10.1016/j.phymed.2021.153563 · 2021 · External reference
Mitochondrial respiration inhibition suppresses papillary thyroid carcinoma via PI3K/Akt/FoxO1/Cyclin D1 pathway
10.3389/fonc.2022.900444 · 2022 · External reference
MCC1019, a selective inhibitor of the polo-box domain of polo-like kinase 1 as novel, potent anticancer candidate
10.1016/j.apsb.2019.02.001 · 2019 · External reference
Enhancing Gpx1 palmitoylation to inhibit angiogenesis by targeting PPT1
10.1016/j.redox.2024.103376 · 2024 · External reference
Effects of nanoparticle size, shape, and zeta potential on drug delivery
10.1016/j.ijpharm.2024.124799 · 2024 · External reference
Analyses of microRNA and mRNA expression profiles reveal the crucial interaction networks and pathways for regulation of chicken breast muscle development
10.3389/fgene.2019.00197 · 2019 · External reference
Paeonia suffruticosa Andrews root extract ameliorates photoaging via regulating IRS1/PI3K/FOXO pathway
10.3389/fphar.2025.1520392 · 2025 · External reference
The many roles of IL-7 in B cell development; mediator of survival, proliferation and differentiation
10.1016/j.smim.2012.02.001 · 2012 · External reference
Molecular response and metabolic reprogramming of the spleen coping with cold stress in the Chinese soft-shelled turtle (Pelodiscus sinensis)
10.3390/antiox14020217 · 2025 · External reference
Integrated multi-omics analysis reveals the mechanisms of intestinal cell injury under different levels of heat stress
10.3390/ijms26125798 · 2025 · External reference
Enhanced SLC2A4 expression mitigates insulin resistance in gestational diabetes mellitus via the FoxO signaling pathway in vitro
10.3892/etm.2025.12956 · 2025 · External reference
Identification of key genes and pathways in scleral extracellular matrix remodeling in glaucoma: potential therapeutic agents discovered using bioinformatics analysis
10.7150/ijms.52846 · 2021 · External reference
mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
10.1042/bj20081668 · 2008 · External reference
AKT, FoxO and regulation of apoptosis
10.1016/j.bbamcr.2011.03.010 · 2011 · External reference
Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling
10.1038/s41419-017-0068-6 · 2018 · External reference
Protein kinase Cδ regulates nuclear export of FOXO1 through phosphorylation of the chaperone 14-3-3ζ
10.1007/s00125-015-3744-z · 2015 · External reference
Incidence and outcomes of infectious and noninfectious endophthalmitis after intravitreal injections for age-related macular degeneration
10.1016/j.ophtha.2017.07.005 · 2018 · External reference
Anti-VEGF-resistant retinal diseases: a review of the latest treatment options
10.3390/cells10051049 · 2021 · External reference
Therapeutic strategies targeting ocular vasculopathies: current advances and emerging challenges
10.1016/j.drudis.2025.104496 · 2025 · External reference
A randomized, open-label, multicenter study of switching to brolucizumab with or without a loading dose for patients with suboptimal anatomically controlled neovascular age-related macular degeneration-the FALCON study
10.1007/s00417-022-05591-z · 2022 · External reference
Bispecific peptide binds to VEGFR2 and Integrin αvβ3, forming an artificial extracellular matrix for anti-ocular neoangiogenesis
10.1002/smll.202409664 · 2025 · External reference
Nanomaterial-based anti-angiogenic gene therapy for retinal neovascular diseases: mechanistic insights and preclinical advances
10.2147/ijn.s521960 · 2025 · External reference
Immunomodulatory activity of manganese dioxide nanoparticles: promising for novel vaccines and immunotherapeutics
10.3389/fimmu.2023.1128840 · 2023 · External reference
Brain-targeting biomimetic disguised manganese dioxide nanoparticles via hybridization of tumor cell membrane and bacteria vesicles for synergistic chemotherapy/chemodynamic therapy of glioma
10.1016/j.jcis.2024.07.121 · 2024 · External reference
Activatable UCL/CT/MR-enhanced in vivo imaging-guided radiotherapy and photothermal therapy
10.1039/d1tb02006d · 2022 · External reference
O(2)-generating MnO(2) nanoparticles for enhanced photodynamic therapy of bladder cancer by ameliorating hypoxia
10.7150/thno.22465 · 2018 · External reference
Basic and therapeutic aspects of angiogenesis updated
10.1161/circresaha.120.316851 · 2020 · External reference
Targeting proliferative retinopathy: arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
10.1038/s41419-022-05196-8 · 2022 · External reference
Effects of biodegradable biomedical porous MnO(2) nanoparticles on blood components and functions
10.1016/j.colsurfb.2022.112667 · 2022 · External reference
Responsive manganese-based nanoplatform amplifying cGAS-STING activation for immunotherapy
10.1186/s40824-023-00374-x · 2023 · External reference
Simultaneous Fenton-like ion delivery and glutathione depletion by MnO(2) -based nanoagent to enhance chemodynamic therapy
10.1002/anie.201712027 · 2018 · External reference
MnO(2) nanotube-based nano search light for imaging of multiple microRNAs in live cells
10.1021/acsami.6b15387 · 2017 · External reference
A dual-signal optical sensing platform of CDs-MnO(2) NS composites for facile detection of ascorbic acid based on a combination of Tyndall effect scattering and fluorescence
10.1039/d4ra02340d · 2024 · External reference
Bioconjugated manganese dioxide nanoparticles enhance chemotherapy response by priming tumor-associated macrophages toward M1-like Phenotype and attenuating tumor hypoxia
10.1021/acsnano.5b06779 · 2016 · External reference
Accurate identification of myocardial viability after myocardial infarction with novel manganese chelate-based MR imaging
10.1002/nbm.4158 · 2019 · External reference
Macrophage membrane coated manganese dioxide nanoparticles loaded with rapamycin alleviate intestinal ischemia-reperfusion injury by reducing oxidative stress and enhancing autophagy
10.2147/ijn.s507546 · 2025 · External reference
Biodegradable and renal clearable inorganic nanoparticles
10.1002/advs.201500223 · 2016 · External reference
Overcoming the stability, toxicity, and biodegradation challenges of tumor stimuli-responsive inorganic nanoparticles for delivery of cancer therapeutics
10.1080/17425247.2019.1662786 · 2019 · External reference
Manganese dioxide-based in situ vaccine boosts antitumor immunity via simultaneous activation of immunogenic cell death and the STING pathway
10.1016/j.actbio.2025.01.029 · 2025 · External reference
Tumor oxygenation and hypoxia inducible Factor-1 functional inhibition via a reactive oxygen species responsive nanoplatform for enhancing radiation therapy and Abscopal effects
10.1021/acsnano.8b03590 · 2018 · External reference
ROS-responsive polymeric micelles for triggered simultaneous delivery of PLK1 Inhibitor/miR-34a and effective synergistic therapy in pancreatic cancer
10.1021/acsami.9b02756 · 2019 · External reference
Auranofin and reactive oxygen species inhibit protein synthesis and regulate the level of the PLK1 protein in Ewing sarcoma cells
10.3389/fonc.2024.1394653 · 2024 · External reference
p53-Dependent and cell specific epigenetic regulation of the polo-like kinases under oxidative stress
10.1371/journal.pone.0087918 · 2014 · External reference
Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy
10.1038/nrd3184 · 2010 · External reference
Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer
10.1136/gutjnl-2016-311393 · 2016 · External reference
Adiponectin suppresses pathological microvessel formation in retina through modulation of tumor necrosis factor-alpha expression
10.1161/circresaha.109.194506 · 2009 · External reference
Pharmacological HIF inhibition prevents retinal neovascularization with improved visual function in a murine oxygen-induced retinopathy model
10.1016/j.neuint.2019.03.008 · 2019 · External reference
Targeting ATF6 reduces pathological neovascularization and improves visual outcomes in retinal disease models
10.1038/s41598-025-15393-y · 2025 · External reference
Influences of placental growth factor on mouse retinal vascular development
10.1002/dvdy.24540 · 2017 · External reference
C176-loaded and phosphatidylserine-modified nanoparticles treat retinal neovascularization by promoting M2 macrophage polarization
10.1016/j.bioactmat.2024.05.038 · 2024 · External reference
The mechanism of CCN1-enhanced retinal neovascularization in oxygen-induced retinopathy through PI3K/Akt-VEGF signaling pathway
10.2147/dddt.s79782 · 2015 · External reference
Panretinal photocoagulation vs intravitreous ranibizumab for proliferative diabetic retinopathy: a randomized clinical trial
10.1001/jama.2015.15217 · ExternalCitation · doi-reference
Persistent macular thickening after ranibizumab treatment for diabetic macular edema with vision Impairment
10.1001/jamaophthalmol.2015.5346 · ExternalCitation · doi-reference
Efficacy of every four monthly and quarterly dosing of faricimab vs ranibizumab in neovascular age-related macular degeneration: the STAIRWAY Phase 2 randomized clinical trial
10.1001/jamaophthalmol.2020.2699 · ExternalCitation · doi-reference
Biodegradable and renal clearable inorganic nanoparticles
10.1002/advs.201500223 · ExternalCitation · doi-reference
Simultaneous Fenton-like ion delivery and glutathione depletion by MnO(2) -based nanoagent to enhance chemodynamic therapy
10.1002/anie.201712027 · ExternalCitation · doi-reference
Influences of placental growth factor on mouse retinal vascular development
10.1002/dvdy.24540 · ExternalCitation · doi-reference
Accurate identification of myocardial viability after myocardial infarction with novel manganese chelate-based MR imaging
10.1002/nbm.4158 · ExternalCitation · doi-reference
Bispecific peptide binds to VEGFR2 and Integrin αvβ3, forming an artificial extracellular matrix for anti-ocular neoangiogenesis
10.1002/smll.202409664 · ExternalCitation · doi-reference
Protein kinase Cδ regulates nuclear export of FOXO1 through phosphorylation of the chaperone 14-3-3ζ
10.1007/s00125-015-3744-z · ExternalCitation · doi-reference
A randomized, open-label, multicenter study of switching to brolucizumab with or without a loading dose for patients with suboptimal anatomically controlled neovascular age-related macular degeneration-the FALCON study
10.1007/s00417-022-05591-z · ExternalCitation · doi-reference
Manganese dioxide-based in situ vaccine boosts antitumor immunity via simultaneous activation of immunogenic cell death and the STING pathway
10.1016/j.actbio.2025.01.029 · ExternalCitation · doi-reference
Early and long-term responses to anti-vascular endothelial growth factor therapy in diabetic macular edema: analysis of Protocol I data
10.1016/j.ajo.2016.09.012 · ExternalCitation · doi-reference
Clinical Efficacy of switching to faricimab in treatment resistant neovascular age-related macular degeneration: systematic review and meta-analysis
10.1016/j.ajo.2025.08.034 · ExternalCitation · doi-reference
MCC1019, a selective inhibitor of the polo-box domain of polo-like kinase 1 as novel, potent anticancer candidate
10.1016/j.apsb.2019.02.001 · ExternalCitation · doi-reference
AKT, FoxO and regulation of apoptosis
10.1016/j.bbamcr.2011.03.010 · ExternalCitation · doi-reference
C176-loaded and phosphatidylserine-modified nanoparticles treat retinal neovascularization by promoting M2 macrophage polarization
10.1016/j.bioactmat.2024.05.038 · ExternalCitation · doi-reference
Copper oxide nanoparticles: in vitro and in vivo toxicity, mechanisms of action and factors influencing their toxicology
10.1016/j.cbpc.2023.109682 · ExternalCitation · doi-reference
Effects of biodegradable biomedical porous MnO(2) nanoparticles on blood components and functions
10.1016/j.colsurfb.2022.112667 · ExternalCitation · doi-reference
Therapeutic strategies targeting ocular vasculopathies: current advances and emerging challenges
10.1016/j.drudis.2025.104496 · ExternalCitation · doi-reference
Gelation embolism agents suppress clinical TACE-incited pro-metastatic microenvironment against hepatocellular carcinoma progression
10.1016/j.ebiom.2024.105436 · ExternalCitation · doi-reference
Effects of nanoparticle size, shape, and zeta potential on drug delivery
10.1016/j.ijpharm.2024.124799 · ExternalCitation · doi-reference
Brain-targeting biomimetic disguised manganese dioxide nanoparticles via hybridization of tumor cell membrane and bacteria vesicles for synergistic chemotherapy/chemodynamic therapy of glioma
10.1016/j.jcis.2024.07.121 · ExternalCitation · doi-reference
Pharmacological HIF inhibition prevents retinal neovascularization with improved visual function in a murine oxygen-induced retinopathy model
10.1016/j.neuint.2019.03.008 · ExternalCitation · doi-reference
Pathophysiology and mechanisms of severe retinopathy of prematurity
10.1016/j.ophtha.2014.07.050 · ExternalCitation · doi-reference
Incidence and outcomes of infectious and noninfectious endophthalmitis after intravitreal injections for age-related macular degeneration
10.1016/j.ophtha.2017.07.005 · ExternalCitation · doi-reference
Persistence of retinal fluid after anti-VEGF treatment for neovascular age-related macular degeneration: a systematic review and meta-analysis
10.1016/j.oret.2025.01.010 · ExternalCitation · doi-reference
Pristimerin synergistically sensitizes conditionally reprogrammed patient derived-primary hepatocellular carcinoma cells to sorafenib through endoplasmic reticulum stress and ROS generation by modulating Akt/FoxO1/p27(kip1) signaling pathway
10.1016/j.phymed.2021.153563 · ExternalCitation · doi-reference
Molecular pathogenesis of retinal and choroidal vascular diseases
10.1016/j.preteyeres.2015.06.002 · ExternalCitation · doi-reference
Incomplete response to anti-VEGF therapy in neovascular AMD: exploring disease mechanisms and therapeutic opportunities
10.1016/j.preteyeres.2020.100906 · ExternalCitation · doi-reference
Enhancing Gpx1 palmitoylation to inhibit angiogenesis by targeting PPT1
10.1016/j.redox.2024.103376 · ExternalCitation · doi-reference
The many roles of IL-7 in B cell development; mediator of survival, proliferation and differentiation
10.1016/j.smim.2012.02.001 · ExternalCitation · doi-reference
Retinal angiomatous proliferation
10.1016/j.survophthal.2017.01.008 · ExternalCitation · doi-reference
Diabetic retinopathy
10.1016/s0140-6736(09)62124-3 · ExternalCitation · doi-reference
Screening for diabetic retinopathy: new perspectives and challenges
10.1016/s2213-8587(19)30411-5 · ExternalCitation · doi-reference
MnO(2) nanotube-based nano search light for imaging of multiple microRNAs in live cells
10.1021/acsami.6b15387 · ExternalCitation · doi-reference
ROS-responsive polymeric micelles for triggered simultaneous delivery of PLK1 Inhibitor/miR-34a and effective synergistic therapy in pancreatic cancer
10.1021/acsami.9b02756 · ExternalCitation · doi-reference
Bioconjugated manganese dioxide nanoparticles enhance chemotherapy response by priming tumor-associated macrophages toward M1-like Phenotype and attenuating tumor hypoxia
10.1021/acsnano.5b06779 · ExternalCitation · doi-reference
Spatiotemporally controlled co-treatment of lung cancer and pulmonary immune-related adverse events by inhalable albumin-chaperoned ultrathin MnO(2) nanosheets
10.1021/acsnano.5c01888 · ExternalCitation · doi-reference
Tumor oxygenation and hypoxia inducible Factor-1 functional inhibition via a reactive oxygen species responsive nanoplatform for enhancing radiation therapy and Abscopal effects
10.1021/acsnano.8b03590 · ExternalCitation · doi-reference
Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy
10.1038/nrd3184 · ExternalCitation · doi-reference
Diabetic retinopathy
10.1038/nrdp.2016.12 · ExternalCitation · doi-reference
Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling
10.1038/s41419-017-0068-6 · ExternalCitation · doi-reference
Targeting proliferative retinopathy: arginase 1 limits vitreoretinal neovascularization and promotes angiogenic repair
10.1038/s41419-022-05196-8 · ExternalCitation · doi-reference
Correction: diabetic retinopathy and diabetic macular oedema pathways and management: UK consensus working group
10.1038/s41433-020-1087-6 · ExternalCitation · doi-reference
Short-term response to anti-VEGF as indicator of visual prognosis in refractory age-related macular degeneration
10.1038/s41433-023-02900-6 · ExternalCitation · doi-reference
Author correction: transcriptomics-based investigation of manganese dioxide nanoparticle toxicity in rats’ choroid plexus
10.1038/s41598-024-59889-5 · ExternalCitation · doi-reference
Targeting ATF6 reduces pathological neovascularization and improves visual outcomes in retinal disease models
10.1038/s41598-025-15393-y · ExternalCitation · doi-reference
MnO(2)-Based nanosystems for cancer therapy
10.1039/d0cc02782k · ExternalCitation · doi-reference
Enzymatically synthesised MnO(2) nanoparticles for efficient near-infrared photothermal therapy and dual-responsive magnetic resonance imaging
10.1039/d1nr02400k · ExternalCitation · doi-reference
Activatable UCL/CT/MR-enhanced in vivo imaging-guided radiotherapy and photothermal therapy
10.1039/d1tb02006d · ExternalCitation · doi-reference
A dual-signal optical sensing platform of CDs-MnO(2) NS composites for facile detection of ascorbic acid based on a combination of Tyndall effect scattering and fluorescence
10.1039/d4ra02340d · ExternalCitation · doi-reference
mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
10.1042/bj20081668 · ExternalCitation · doi-reference
Diabetic retinopathy
10.1056/nejmra1005073 · ExternalCitation · doi-reference
Overcoming the stability, toxicity, and biodegradation challenges of tumor stimuli-responsive inorganic nanoparticles for delivery of cancer therapeutics
10.1080/17425247.2019.1662786 · ExternalCitation · doi-reference
Good initial visual acuity in patients with macular edema due to retinal vein occlusion: management and outcomes
10.1097/iae.0000000000004244 · ExternalCitation · doi-reference
A systematic review of the adverse events of intravitreal anti-vascular endothelial growth factor injections
10.1097/iae.0b013e3182278ab4 · ExternalCitation · doi-reference
Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy
10.1126/science.aay5356 · ExternalCitation · doi-reference
Dexamethasone intravitreal implant in diabetic macular oedema refractory to anti-vascular endothelial growth factors: the AUSSIEDEX study
10.1136/bmjophth-2022-001224 · ExternalCitation · doi-reference
Tracking real-world persistence and adherence to anti-VEGF intravitreal therapy with prefilled syringes: a German prescription sales analysis
10.1136/bmjophth-2025-002334 · ExternalCitation · doi-reference
Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer
10.1136/gutjnl-2016-311393 · ExternalCitation · doi-reference
Factors affecting intensive aflibercept treatment response in diabetic macular edema: a real-world study
10.1155/2023/1485059 · ExternalCitation · doi-reference
Adiponectin suppresses pathological microvessel formation in retina through modulation of tumor necrosis factor-alpha expression
10.1161/circresaha.109.194506 · ExternalCitation · doi-reference
Basic and therapeutic aspects of angiogenesis updated
10.1161/circresaha.120.316851 · ExternalCitation · doi-reference
Retinal and choroidal vascular diseases: past, present, and future: the 2021 proctor lecture
10.1167/iovs.62.14.26 · ExternalCitation · doi-reference
Efficacy and safety of dexamethasone versus intravitreal aflibercept implants for macular edema: a systematic review and meta-analysis
10.1186/s40001-025-02404-x · ExternalCitation · doi-reference
Responsive manganese-based nanoplatform amplifying cGAS-STING activation for immunotherapy
10.1186/s40824-023-00374-x · ExternalCitation · doi-reference
Onvansertib in combination with chemotherapy and bevacizumab in second-line treatment of KRAS-mutant metastatic colorectal cancer: a single-arm, Phase II trial
10.1200/jco-24-01266 · ExternalCitation · doi-reference
p53-Dependent and cell specific epigenetic regulation of the polo-like kinases under oxidative stress
10.1371/journal.pone.0087918 · ExternalCitation · doi-reference
The mechanism of CCN1-enhanced retinal neovascularization in oxygen-induced retinopathy through PI3K/Akt-VEGF signaling pathway
10.2147/dddt.s79782 · ExternalCitation · doi-reference
Manganese dioxide nanosheets: from preparation to biomedical applications
10.2147/ijn.s207666 · ExternalCitation · doi-reference
Macrophage membrane coated manganese dioxide nanoparticles loaded with rapamycin alleviate intestinal ischemia-reperfusion injury by reducing oxidative stress and enhancing autophagy
10.2147/ijn.s507546 · ExternalCitation · doi-reference
Nanomaterial-based anti-angiogenic gene therapy for retinal neovascular diseases: mechanistic insights and preclinical advances
10.2147/ijn.s521960 · ExternalCitation · doi-reference
Baseline visual acuity strongly predicts visual acuity gain in patients with diabetic macular edema following anti-vascular endothelial growth factor treatment across trials
10.2147/opth.s100764 · ExternalCitation · doi-reference
Copper oxide nanoparticles suppress retinal angiogenesis via inducing endothelial cell cuproptosis
10.2217/nnm-2023-0301 · ExternalCitation · doi-reference
A real-world study for timely assessing the diabetic macular edema refractory to intravitreal anti-VEGF treatment
10.3389/fendo.2023.1108097 · ExternalCitation · doi-reference
Analyses of microRNA and mRNA expression profiles reveal the crucial interaction networks and pathways for regulation of chicken breast muscle development
10.3389/fgene.2019.00197 · ExternalCitation · doi-reference
Immunomodulatory activity of manganese dioxide nanoparticles: promising for novel vaccines and immunotherapeutics
10.3389/fimmu.2023.1128840 · ExternalCitation · doi-reference
Mitochondrial respiration inhibition suppresses papillary thyroid carcinoma via PI3K/Akt/FoxO1/Cyclin D1 pathway
10.3389/fonc.2022.900444 · ExternalCitation · doi-reference
Auranofin and reactive oxygen species inhibit protein synthesis and regulate the level of the PLK1 protein in Ewing sarcoma cells
10.3389/fonc.2024.1394653 · ExternalCitation · doi-reference
Paeonia suffruticosa Andrews root extract ameliorates photoaging via regulating IRS1/PI3K/FOXO pathway
10.3389/fphar.2025.1520392 · ExternalCitation · doi-reference
Molecular response and metabolic reprogramming of the spleen coping with cold stress in the Chinese soft-shelled turtle (Pelodiscus sinensis)
10.3390/antiox14020217 · ExternalCitation · doi-reference
Anti-VEGF-resistant retinal diseases: a review of the latest treatment options
10.3390/cells10051049 · ExternalCitation · doi-reference
The role of polo-like Kinase 1 in regulating the forkhead box family transcription factors
10.3390/cells12091344 · ExternalCitation · doi-reference
Integrated multi-omics analysis reveals the mechanisms of intestinal cell injury under different levels of heat stress
10.3390/ijms26125798 · ExternalCitation · doi-reference
Fucoidan-manganese dioxide nanoparticles potentiate radiation therapy by co-targeting tumor hypoxia and angiogenesis
10.3390/md16120510 · ExternalCitation · doi-reference
Enhanced SLC2A4 expression mitigates insulin resistance in gestational diabetes mellitus via the FoxO signaling pathway in vitro
10.3892/etm.2025.12956 · ExternalCitation · doi-reference
One-year outcomes of Aflibercept for refractory diabetic macular edema in Bevacizumab nonresponders
10.4103/ijo.ijo_459_20 · ExternalCitation · doi-reference
Manganese dioxide nanoparticle induces Parkinson like neurobehavioral abnormalities in rats
10.4149/bll_2018_070 · ExternalCitation · doi-reference
Identification of key genes and pathways in scleral extracellular matrix remodeling in glaucoma: potential therapeutic agents discovered using bioinformatics analysis
10.7150/ijms.52846 · ExternalCitation · doi-reference
O(2)-generating MnO(2) nanoparticles for enhanced photodynamic therapy of bladder cancer by ameliorating hypoxia
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