Research graph
References from Recent developments in fluorescence lifetime imaging of lipid membrane dynamics. Local targets link to admitted publications; unresolved targets remain external evidence.
Regulation of membrane protein structure and function by their lipid nano-environment
10.1038/s41580-022-00524-4 · 2023 · External reference
Membrane lipids: where they are and how they behave
10.1038/nrm2330 · 2008 · External reference
Generation of nanoscopic membrane curvature for membrane trafficking
10.1038/s41580-022-00511-9 · 2023 · External reference
Understanding the diversity of membrane lipid composition
10.1038/nrm.2017.138 · 2018 · External reference
Biological membrane organization and cellular signaling
10.1021/acs.chemrev.8b00439 · 2019 · External reference
Biophysics in cancer: the relevance of drug-membrane interaction studies
10.1016/j.bbamem.2016.06.025 · 2016 · External reference
Simultaneous visualization of membrane fluidity and morphology defines adhesion signatures of cancer cells
10.1073/pnas.2412914121 · 2024 · External reference
Lipidomic landscape in cancer: actionable insights for membrane-based therapy and diagnoses
10.1002/med.21868 · 2022 · External reference
4D analysis of malaria parasite invasion offers insights into erythrocyte membrane remodeling and parasitophorous vacuole formation
10.1038/s41467-021-23626-7 · 2021 · External reference
Of membranes and malaria: phospholipid asymmetry in Plasmodium falciparum-infected red blood cells
10.1007/s00018-021-03799-6 · 2021 · External reference
Brain lipid peroxidation and Alzheimer disease: synergy between the Butterfield and Mattson laboratories
10.1016/j.arr.2020.101049 · 2020 · External reference
Lipid peroxidation in neurodegeneration
10.1016/j.cca.2019.07.037 · 2019 · External reference
Oxidized phospholipids: emerging lipid mediators in pathophysiology
10.1097/mol.0b013e3282fe1d0e · 2008 · External reference
Molecular mechanisms of lipid metabolism disorders in infectious exacerbations of chronic obstructive pulmonary disease
10.3390/ijms22147634 · 2021 · External reference
Nanoscale viscometry reveals an inherent mucus defect in cystic fibrosis
10.1021/acsnano.4c14927 · 2025 · External reference
The role of oxidized phospholipids in atherosclerosis
10.1194/jlr.r800074-jlr200 · 2009 · External reference
Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice
10.1038/s41586-018-0198-8 · 2018 · External reference
Spectral biophysical cytometry with nanosensors reveals remodelling of immune cells in atherosclerosis
10.1038/s41565-026-02236-8 · 2026 · External reference
Vascular endothelial cell membranes differentiate between stretch and shear stress through transitions in their lipid phases
10.1152/ajpheart.00241.2015 · 2015 · External reference
Targeted liposomal drug delivery: a nanoscience and biophysical perspective
10.1039/d0nh00605j · 2021 · External reference
Membrane fluidity as a new means to selectively target cancer cells with fusogenic lipid carriers
10.1021/acs.langmuir.0c00262 · 2020 · External reference
Membrane fusion‐based drug delivery liposomes transiently modify the material properties of synthetic and biological membranes
10.1002/smll.202408039 · 2025 · External reference
Dynamic reconfiguration of subcompartment architectures in artificial cells
10.1021/acsnano.2c02195 · 2022 · External reference
Ion- and temperature-programmable reconfiguration of subcompartments in synthetic cells
10.1002/cbic.202500928 · 2026 · External reference
A tuneable minimal cell membrane reveals that two lipid species suffice for life
10.1038/s41467-024-53975-y · 2024 · External reference
Local mapping of the nanoscale viscoelastic properties of fluid membranes by AFM nanorheology
10.1038/s41467-025-59260-w · 2025 · External reference
Effects of lipid composition on bilayer membranes quantified by all-atom molecular dynamics
10.1021/acs.jpcb.5b06604 · 2015 · External reference
Lateral pressure in membranes
10.1016/s0304-4157(96)00009-3 · 1996 · External reference
Membranes using Di-Pyrenyl phosphatidylcholine
1998 · External reference
Structural and functional consequences of reversible lipid asymmetry in living membranes
10.1038/s41589-020-00688-0 · 2020 · External reference
Spontaneous curvature, differential stress, and bending modulus of asymmetric lipid membranes
10.1016/j.bpj.2019.11.3398 · 2020 · External reference
Identifying optimal lipid raft characteristics required to promote nanoscale protein-protein interactions on the plasma membrane
10.1128/mcb.26.1.313-323.2006 · 2006 · External reference
Receptor/Raft Ratio Is a Determinant for LRP6 Phosphorylation and WNT/β-catenin signaling
10.3389/fcell.2021.706731 · 2021 · External reference
Impact of lipid rafts on the T -cell-receptor and peptide-major-histocompatibility-complex interactions under different measurement conditions
10.1103/physreve.95.012403 · 2017 · External reference
Lipid rafts and signal transduction
10.1038/35036052 · 2000 · External reference
Disruption of palmitate-mediated localization; a shared pathway of force and anesthetic activation of TREK-1 channels
10.1016/j.bbamem.2019.183091 · 2020 · External reference
Kinetic disruption of lipid rafts is a mechanosensor for phospholipase D
10.1038/ncomms13873 · 2016 · External reference
Phases and phase transitions of the phosphatidylcholines
10.1016/s0304-4157(98)00006-9 · 1998 · External reference
Structure of the fully hydrated gel phase of dipalmitoylphosphatidylcholine
10.1016/s0006-3495(89)82807-3 · 1989 · External reference
Structure of gel phase DPPC determined by x-ray diffraction
10.1016/j.chemphyslip.2018.12.011 · 2019 · External reference
Lateral order in gel, subgel and crystalline phases of lipid membranes: wide-angle x-ray scattering
10.1016/j.chemphyslip.2011.11.001 · 2012 · External reference
Lipid crystallization: from self-assembly to hierarchical and biological ordering
10.1039/c2nr31465g · 2012 · External reference
Viscosity-sensitive membrane dyes as tools to estimate the crystalline structure of lipid bilayers
10.1021/acs.analchem.3c01747 · 2023 · External reference
Bilayer polarity and its thermal dependency in the ℓo and ℓd phases of binary phosphatidylcholine/cholesterol mixtures
10.1016/j.bbamem.2007.08.012 · 2007 · External reference
On scattered waves and lipid domains: detecting membrane rafts with x-rays and neutrons
10.1039/c5sm01807b · 2015 · External reference
Biophysical perspective advances in micropipette aspiration: applications in cell biomechanics, models, and extended studies
10.1016/j.bpj.2019.01.004 · 2019 · External reference
Advances in nanomechanical property mapping by atomic force microscopy
10.1039/d5na00702j · 2025 · External reference
Nanomechanics of lipid bilayers by force spectroscopy with AFM : a perspective
10.1016/j.bbamem.2009.12.019 · 2010 · External reference
Fluctuation spectroscopy of giant unilamellar vesicles using confocal and phase contrast microscopy
10.1039/d0sm00943a · 2020 · External reference
Viscoelastic deformation of lipid bilayer vesicles
10.1039/c5sm01565k · 2015 · External reference
Optical tweezers microrheology: from the basics to advanced techniques and applications
10.1021/acsmacrolett.8b00498 · 2018 · External reference
Brillouin microscopy
10.1038/s43586-023-00286-z · 2024 · External reference
Brillouin microscopy: an emerging tool for mechanobiology
10.1038/s41592-019-0543-3 · 2019 · External reference
Brillouin light scattering: applications in biomedical sciences
10.1021/acs.chemrev.9b00019 · 2019 · External reference
A comprehensive review of fluorescence correlation spectroscopy
10.3389/fphy.2021.644450 · 2021 · External reference
Single particle tracking: from theory to biophysical applications
10.1021/acs.chemrev.6b00815 · 2017 · External reference
Fluorescence recovery after photobleaching in material and life sciences: putting theory into practice
10.1017/s0033583515000013 · 2015 · External reference
Fluorescent probes for lipid membranes: from the cell surface to organelles
10.1021/acs.accounts.2c00586 · 2023 · External reference
Fluorescent flippers: small‐molecule probes to image membrane tension in living systems
10.1002/anie.202217868 · 2023 · External reference
Molecular rotors: fluorescent sensors for microviscosity and conformation of biomolecules
10.1002/anie.202311233 · 2024 · External reference
Exploring the physical properties of lipid membranes with polyhydroxy oxanorbornane head group using NBD-conjugated and DPH fluorescent probes
10.1021/acs.langmuir.3c02941 · 2024 · External reference
Quantifying fluorescence lifetime responsiveness of environment-sensitive probes for membrane fluidity measurements
10.1021/acs.jpcb.3c07006 · 2024 · External reference
A review of new high-throughput methods designed for fluorescence lifetime sensing from cells and tissues
10.3389/fphy.2021.648553 · 2021 · External reference
Fluorescence lifetime imaging for the two-photon microscope: time-domain and frequency-domain methods
10.1117/1.1586704 · 2003 · External reference
Molecular rheometry: direct determination of viscosity in Lo and Ld lipid phases via fluorescence lifetime imaging
10.1039/c3cp51953h · 2013 · External reference
Imaging phase separation in model lipid membranes through the use of BODIPY based molecular rotors
10.1039/c5cp01937k · 2015 · External reference
Solvatochromic and fluorogenic dyes as environment-sensitive probes: design and biological applications
10.1021/acs.accounts.6b00517 · 2017 · External reference
LAURDAN since weber: the quest for visualizing membrane heterogeneity
10.1021/acs.accounts.0c00687 · 2021 · External reference
Characterization and application of a new optical probe for membrane lipid domains
10.1529/biophysj.105.072884 · 2006 · External reference
Sensing cholesterol-induced rigidity in model membranes with time-resolved fluorescence spectroscopy and microscopy
10.1039/d4tb00872c · 2024 · External reference
A closer look into Laurdan as a probe to monitor cationic DODAB bilayers
10.1016/j.jphotochem.2019.03.006 · 2019 · External reference
Laurdan fluorescence lifetime discriminates cholesterol content from changes in fluidity in living cell membranes
10.1016/j.bpj.2012.12.057 · 2013 · External reference
Time-resolved Laurdan fluorescence reveals insights into membrane viscosity and hydration levels
10.1016/j.bpj.2018.08.041 · 2018 · External reference
Fluorescence lifetime imaging provides enhanced contrast when imaging the phase-sensitive dye di-4-ANEPPDHQ in model membranes and live cells
10.1529/biophysj.106.084673 · 2006 · External reference
Lipid peroxidation drives liquid-liquid phase separation and disrupts raft protein partitioning in biological membranes
10.1021/jacs.3c10132 · 2024 · External reference
A fluorescent membrane tension probe
10.1038/s41557-018-0127-3 · 2018 · External reference
Tensing flipper: photosensitized manipulation of membrane tension, lipid phase separation, and raft protein sorting in biological membranes
10.1021/jacs.4c08580 · 2024 · External reference
Fluorescence probe for microenvironments: anomalous viscosity dependence of the fluorescence quantum yield of p-N,N-dialkylaminobenzylidenemalononitrile in 1-alkanols
10.1016/0009-2614(80)80574-4 · 1980 · External reference
Effect of viscosity and temperature on torsional relaxation of molecular rotors
10.1021/j100218a023 · 1982 · External reference
Environment-sensitive behavior of fluorescent molecular rotors
10.1186/1754-1611-4-11 · 2010 · External reference
Effects of solvent polarity and solvent viscosity on the fluorescent properties of molecular rotors and related probes
10.1016/j.bioorg.2005.07.005 · 2005 · External reference
Solvatochromic near-infrared probe for polarity mapping of biomembranes and lipid droplets in cells under stress
10.1021/acs.jpclett.9b00668 · 2019 · External reference
Unravelling the effect of temperature on viscosity-sensitive fluorescent molecular rotors
10.1039/c5sc02248g · 2015 · External reference
Molecular rotors—fluorescent biosensors for viscosity and flow
10.1039/b618415d · 2007 · External reference
Molecular rotor measures viscosity of live cells via fluorescence lifetime imaging
10.1021/ja800570d · 2008 · External reference
A molecular rotor for measuring viscosity in plasma membranes of live cells
10.1039/c3cc47530a · 2014 · External reference
Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density
10.1038/s42003-019-0583-3 · 2019 · External reference
Solvatochromic modeling of Laurdan for multiple polarity analysis of dihydrosphingomyelin bilayer
10.1016/j.bpj.2019.01.030 · 2019 · External reference
Spectrally resolved fluorescence lifetime imaging of Nile red for measurements of intracellular polarity
10.1117/1.jbo.20.9.096002 · 2015 · External reference
Exploring viscosity, polarity and temperature sensitivity of BODIPY-based molecular rotors
10.1039/c7cp03571c · 2017 · External reference
Probing supramolecular protein assembly using covalently attached fluorescent molecular rotors
10.1016/j.biomaterials.2017.06.009 · 2017 · External reference
Imaging non-classical mechanical responses of lipid membranes using molecular rotors
10.1039/d0sc05874b · 2021 · External reference
Viscosity dependence of fluorescent quantum yields of some dye systems
10.1524/zpch.1971.75.1_2.063 · 1971 · External reference
The effect of solvent polarity and macromolecular crowding on the viscosity sensitivity of a molecular rotor BODIPY-C 10
10.1039/c9cp06865a · 2020 · External reference
Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties
10.1016/j.bpj.2022.11.1332 · 2022 · External reference
Fluorescence lifetime imaging microscopy of flexible and rigid dyes probes the biophysical properties of synthetic and biological membranes
10.1016/j.bpj.2024.04.033 · 2024 · External reference
Sensing membrane stress with near IR-emissive porphyrins
10.1073/pnas.1102125108 · 2011 · External reference
Directly imaging emergence of phase separation in peroxidized lipid membranes
10.1038/s42004-022-00809-x · 2023 · External reference
Correlation of plasma membrane microviscosity and cell stiffness revealed via fluorescence-lifetime imaging and atomic force microscopy
10.3390/cells12212583 · 2023 · External reference
Visualizing actin packing and the effects of actin attachment on lipid membrane viscosity using molecular rotors
10.1021/jacsau.4c00237 · 2024 · External reference
A tunable palette of molecular rotors allows multicolor, ratiometric fluorescence imaging and direct mapping of mitochondrial heterogeneity
10.1021/acsabm.1c00135 · 2021 · External reference
Facile synthesis of highly sensitive, red-emitting, fluorogenic dye for microviscosity and mitochondrial imaging in embryonic stem cells
10.1002/slct.201700463 · 2017 · External reference
Near infrared emitting molecular rotor based on merocyanine for probing the viscosity of cellular lipid environments
10.1039/d0qm00872a · 2021 · External reference
Imaging plasma membrane phase behaviour in live cells using a thiophene-based molecular rotor
10.1039/c6cc05954f · 2016 · External reference
Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape
10.1038/s41589-020-0529-6 · 2020 · External reference
Photocleavable fluorescent membrane tension probes: fast release with spatiotemporal control in inner leaflets of plasma membrane, nuclear envelope, and secretory pathway
10.1002/anie.202113163 · 2022 · External reference
Designing a red-emitting viscosity-sensitive bodipy fluorophore for intracellular viscosity imaging
10.1002/chem.202102743 · 2021 · External reference
Tuning BODIPY molecular rotors into the red: sensitivity to viscosity vs. temperature
10.1039/c5tc02954f · 2016 · External reference
Cyclopropyl substituents transform the viscosity-sensitive BODIPY molecular rotor into a temperature sensor
10.1021/acssensors.0c02275 · 2021 · External reference
Sensing temperature in vitro and in cells using a BODIPY molecular probe
10.1021/acs.jpcb.9b04384 · 2019 · External reference
Fluorescent flipper probes: comprehensive twist coverage
10.1002/chem.201903604 · 2019 · External reference
Hydrophobic interfacing of fluorescent membrane probes
10.1002/ceur.202300041 · 2023 · External reference
Fluorescent flippers for mechanosensitive membrane probes
10.1021/ja5107018 · 2015 · External reference
Thiophene-based dyes for probing membranes
10.1039/c4ob02507e · 2015 · External reference
Sub-resolution lipid domains exist in the plasma membrane and regulate protein diffusion and distribution
10.1038/ncomms2273 · 2012 · External reference
Lipid rafts: controversies resolved, mysteries remain
10.1016/j.tcb.2020.01.009 · 2020 · External reference
Fit-free analysis of fluorescence lifetime imaging data using the phasor approach
10.1038/s41596-018-0026-5 · 2018 · External reference
Quantitative imaging of membrane lipid order in cells and organisms
10.1038/nprot.2011.419 · 2012 · External reference
Fluorescent solvatochromic probes for long-term imaging of lipid order in living cells
10.1002/advs.202309721 · 2024 · External reference
Redesigning solvatochromic probe Laurdan for imaging lipid order selectively in cell plasma membranes
10.1021/acs.analchem.0c03559 · 2020 · External reference
Headgroup engineering in mechanosensitive membrane probes
10.1039/c6cc08771j · 2016 · External reference
Immune cell activation produces locally scrambled foci of plasma membrane lipids
10.1039/d4fd00205a · 2025 · External reference
Loss of lipid asymmetry facilitates plasma membrane blebbing by decreasing membrane lipid packing
10.1073/pnas.2417145122 · 2025 · External reference
An optical technique for mapping microviscosity dynamics in cellular organelles
10.1021/acsnano.8b00177 · 2018 · External reference
Z-α 1 -antitrypsin polymers impose molecular filtration in the endoplasmic reticulum after undergoing phase transition to a solid state
10.1126/sciadv.abm2094 · 2022 · External reference
Linker length affects photostability of protein-targeted sensor of cellular microviscosity
10.1088/2050-6120/ab481f · 2019 · External reference
Mapping protein-specific micro-environments in live cells by fluorescence lifetime imaging of a hybrid genetic-chemical molecular rotor tag
10.1039/c2cc33133k · 2012 · External reference
Haloflippers: a general tool for the fluorescence imaging of precisely localized membrane tension changes in living cells
10.1021/acscentsci.0c00666 · 2020 · External reference
Streptavidin interfacing as a general strategy to localize fluorescent membrane tension probes in cells
10.1039/c8sc03620a · 2019 · External reference
Genetically encoded supramolecular targeting of fluorescent membrane tension probes within live cells: precisely localized controlled release by external chemical stimulation
10.1021/jacsau.0c00069 · 2021 · External reference
A molecular rotor that measures dynamic changes of lipid bilayer viscosity caused by oxidative stress
10.1002/chem.201601925 · 2016 · External reference
Molecular rotors report on changes in live cell plasma membrane microviscosity upon interaction with beta-amyloid aggregates
10.1039/c8sm01633j · 2018 · External reference
Effect of ethanol perturbation on viscosity and permeability of an inner membrane in Bacillus subtilis spores
10.1016/j.bbamem.2016.06.003 · 2016 · External reference
Microscopic viscosity of neuronal plasma membranes measured using fluorescent molecular rotors: effects of oxidative stress and neuroprotection
10.1021/acsami.9b10426 · 2019 · External reference
Visualising UV-A light-induced damage to plasma membranes of eye lens
10.1016/j.jphotobiol.2021.112346 · 2021 · External reference
Probing metabolism and viscosity of cancer cells using fluorescence lifetime imaging microscopy
10.3791/62708 · 2021 · External reference
Development of resistance to 5-fluorouracil affects membrane viscosity and lipid composition of cancer cells
10.1088/2050-6120/ac89cd · 2022 · External reference
Unraveling microviscosity changes induced in cancer cells by photodynamic therapy with targeted genetically encoded photosensitizer
10.3390/biomedicines12112550 · 2024 · External reference
Imaging intracellular viscosity of a single cell during photoinduced cell death
10.1038/nchem.120 · 2009 · External reference
Measuring intracellular viscosity in conditions of hypergravity
10.1016/j.bpj.2019.03.038 · 2019 · External reference
Simultaneous detection of carbon monoxide and viscosity changes in cells
10.1002/ange.202008224 · 2020 · External reference
Monitoring membrane viscosity in differentiating stem cells using BODIPY-based molecular rotors and FLIM
10.1038/s41598-020-70972-5 · 2020 · External reference
Mapping cisplatin-induced viscosity alterations in cancer cells using molecular rotor and fluorescence lifetime imaging microscopy
10.1117/1.jbo.25.12.126004 · 2020 · External reference
Elastic remodeling of model and cell membranes by rotating ATP synthase
10.1016/j.xcrp.2025.102567 · 2025 · External reference
Adherent cells sustain membrane tension gradients independently of migration
10.1038/s41467-025-65571-9 · 2025 · External reference
Photodynamic therapy with Photoditazine increases microviscosity of cancer cells membrane in cellulo and in vivo
10.1016/j.jphotobiol.2024.113007 · 2024 · External reference
Lipid hydroperoxide compromises the membrane structure organization and softens bending rigidity
10.1021/acs.langmuir.1c00830 · 2021 · External reference
Curvature softening and negative compressibility of gel-phase lipid membranes
10.1021/jacs.5b06800 · 2015 · External reference
Decrease in plasma membrane tension triggers PtdIns(4,5)P 2 phase separation to inactivate TORC2
10.1038/s41556-018-0150-z · 2018 · External reference
Influence of simvastatin and pravastatin on the biophysical properties of model lipid bilayers and plasma membranes of live cells
10.1021/acsbiomaterials.4c00911 · 2024 · External reference
Substrate stiffness-driven membrane tension modulates vesicular trafficking via Caveolin-1
10.1021/acsnano.1c10534 · 2022 · External reference
The role of plasma membrane viscosity in the response and resistance of cancer cells to oxaliplatin
10.3390/cancers13246165 · 2021 · External reference
Evaluation of membrane fluidity of multidrug-resistant isolates of Escherichia coli and Staphylococcus aureus in presence and absence of antibiotics
10.1016/j.jphotobiol.2018.03.002 · 2018 · External reference
Mechanical properties that influence antimicrobial peptide activity in lipid membranes
10.1007/s00253-016-7975-9 · 2016 · External reference
Exploring bacteria–surface interactions with a fluorescent membrane tension probe
10.1073/pnas.2512977122 · 2025 · External reference
Peptide-membrane interactions monitored by fluorescence lifetime imaging: a study case of transportan 10
10.1021/acs.langmuir.1c02392 · 2021 · External reference
Biomolecular condensates modulate membrane lipid packing and hydration
10.1038/s41467-023-41709-5 · 2023 · External reference
Addressing challenges in the removal of unbound dye from passively labelled extracellular vesicles
10.1039/d1na00755f · 2022 · External reference
A robust and versatile platform for image scanning microscopy enabling super-resolution FLIM
10.1038/s41592-018-0291-9 · 2019 · External reference
Super-resolution FLIM imaging of intracellular lipid microenvironments with a dual-responsive polarity- and pH-sensitive fluorescent probe
10.1021/acs.analchem.5c00826 · 2025 · External reference
Fluorescence lifetime DNA-PAINT for multiplexed super-resolution imaging of cells
10.1038/s42003-021-02976-4 · 2022 · External reference
Single-molecule localization microscopy and tracking with a fluorescent mechanosensitive probe
10.1021/acs.jpcb.4c02506 · 2024 · External reference
Fluorescent membrane tension probes for super-resolution microscopy: combining mechanosensitive cascade switching with dynamic-covalent ketone chemistry
10.1021/jacs.0c04942 · 2020 · External reference
Deep learning for fluorescence lifetime predictions enables high-throughput in vivo imaging
10.1021/jacs.5c03749 · 2025 · External reference
Time-domain microfluidic fluorescence lifetime flow cytometry for high-throughput Förster resonance energy transfer screening
10.1002/cyto.a.22616 · 2015 · External reference
High-throughput fluorescence lifetime imaging flow cytometry
10.1038/s41467-024-51125-y · 2024 · External reference
Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish
10.1038/s41467-017-01325-6 · 2017 · External reference
Quantifying T cell receptor mechanics at membrane junctions using DNA origami tension sensors
10.1038/s41565-024-01723-0 · 2024 · External reference
Super-resolved visualization of single DNA-based tension sensors in cell adhesion
10.1038/s41467-021-22606-1 · 2021 · External reference
Advanced DNA Zipper probes for detecting cell membrane lipid domains
10.1021/acs.nanolett.2c02605 · 2022 · External reference
Imaging membrane order and dynamic interactions in living cells with a DNA zipper probe
10.1002/anie.202112033 · 2022 · External reference
