Research graph
References from Gut microbiota associate with disease severity and survival in idiopathic pulmonary fibrosis. Local targets link to admitted publications; unresolved targets remain external evidence.
Microbiome-wide association studies link dynamic microbial consortia to disease
10.1038/nature18850 · 2016 · External reference
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
10.1038/nature12726 · 2013 · External reference
Muc5b is required for airway defence
10.1038/nature12807 · 2014 · External reference
A common MUC5B promoter polymorphism and pulmonary fibrosis
10.1056/nejmoa1013660 · 2011 · External reference
Immune dysregulation as a driver of idiopathic pulmonary fibrosis
10.1172/jci143226 · 2021 · External reference
The lung microbiome
10.4049/jimmunol.2300716 · 2024 · External reference
The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis
10.1164/rccm.201403-0541oc · 2014 · External reference
Commensal oral microbiota, disease severity, and mortality in fibrotic lung disease
10.1164/rccm.202308-1357oc · 2024 · External reference
The gut microbiome is a significant risk factor for future chronic lung disease
10.1016/j.jaci.2022.12.810 · 2023 · External reference
Idiopathic pulmonary fibrosis
10.1056/nejmc1807508 · 2018 · External reference
Horizontal transmission of gut microbiota attenuates mortality in lung fibrosis
10.1172/jci.insight.164572 · 2023 · External reference
Gut microbiota modulates bleomycin-induced acute lung injury response in mice
10.1186/s12931-022-02264-7 · 2022 · External reference
Gut microbiota modulates lung fibrosis severity following acute lung injury in mice
10.1038/s42003-022-04357-x · 2022 · External reference
Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation
10.1038/nm.2657 · 2012 · External reference
The gut microbiota is associated with immune cell dynamics in humans
10.1038/s41586-020-2971-8 · 2020 · External reference
A forward chemical genetic screen reveals gut microbiota metabolites that modulate host physiology
10.1016/j.cell.2019.03.036 · 2019 · External reference
Mapping interactions of microbial metabolites with human G-protein-coupled receptors
10.1016/j.chom.2019.07.002 · 2019 · External reference
Gut microbiota promote hematopoiesis to control bacterial infection
10.1016/j.chom.2014.02.006 · 2014 · External reference
Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands
10.1016/j.immuni.2011.02.016 · 2011 · External reference
Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome
10.1038/nmicrobiol.2016.113 · 2016 · External reference
Effect of antimicrobial therapy on respiratory hospitalization or death in adults with idiopathic pulmonary fibrosis: the CleanUP-IPF randomized clinical trial
10.1001/jama.2021.4956 · 2021 · External reference
Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice
10.1126/scitranslmed.aaf2311 · 2016 · External reference
Antimicrobial therapy and respiratory hospitalization or death in adults with idiopathic pulmonary fibrosis-reply
10.1001/jama.2021.11813 · 2021 · External reference
The gut microbiome modulates body temperature both in sepsis and health
10.1164/rccm.202201-0161oc · 2023 · External reference
Development of a dual-index sequencing strategy and curation pipeline for analyzing amplicon sequence data on the MiSeq Illumina sequencing platform
10.1128/aem.01043-13 · 2013 · External reference
Lung microbiota contribute to pulmonary inflammation and disease progression in pulmonary fibrosis
10.1164/rccm.201809-1650oc · 2019 · External reference
Multivariable association discovery in population-scale meta-omics studies
10.1371/journal.pcbi.1009442 · 2021 · External reference
Self-reported gastrointestinal side effects of antifibrotic drugs in Dutch idiopathic pulmonary fibrosis patients
10.1007/s00408-019-00260-1 · 2019 · External reference
The human intestinal microbiome in health and disease
10.1056/nejmra1600266 · 2016 · External reference
Functional and genomic variation between human-derived isolates of Lachnospiraceae reveals inter- and intra-species diversity
10.1016/j.chom.2020.05.005 · 2020 · External reference
Diet rapidly and reproducibly alters the human gut microbiome
10.1038/nature12820 · 2014 · External reference
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile
10.1038/nature13828 · 2015 · External reference
Depletion of butyrate-producing clostridia from the gut microbiota drives an aerobic luminal expansion of salmonella
10.1016/j.chom.2016.03.004 · 2016 · External reference
Microbiota-derived lantibiotic restores resistance against vancomycin-resistant Enterococcus
10.1038/s41586-019-1501-z · 2019 · External reference
Modulating gut microbiome in cancer immunotherapy: harnessing microbes to enhance treatment efficacy
10.1016/j.xcrm.2024.101478 · 2024 · External reference
Mapping human microbiome drug metabolism by gut bacteria and their genes
10.1038/s41586-019-1291-3 · 2019 · External reference
Fecal microbiota transplant overcomes resistance to anti-PD-1 therapy in melanoma patients
10.1126/science.abf3363 · 2021 · External reference
Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
10.1126/science.aad1329 · 2015 · External reference
Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy
10.1126/science.abc3421 · 2020 · External reference
Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice
10.1038/s41564-020-00831-6 · 2021 · External reference
Longitudinal gut microbiome changes in immune checkpoint blockade-treated advanced melanoma
10.1038/s41591-024-02803-3 · 2024 · External reference
Treating idiopathic pulmonary fibrosis with the addition of co-trimoxazole: a randomised controlled trial
10.1136/thoraxjnl-2012-202403 · 2013 · External reference
Effect of co-trimoxazole (trimethoprim-sulfamethoxazole) vs placebo on death, lung transplant, or hospital admission in patients with moderate and severe idiopathic pulmonary fibrosis: the EME-TIPAC randomized clinical trial
10.1001/jama.2020.22960 · 2020 · External reference
Cotrimoxazole reduces systemic inflammation in HIV infection by altering the gut microbiome and immune activation
10.1126/scitranslmed.aav0537 · 2019 · External reference
Microbiota as predictor of mortality in allogeneic hematopoietic-cell transplantation
10.1056/nejmoa1900623 · 2020 · External reference
Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
10.1038/s41467-020-19701-0 · 2020 · External reference
The theory of disappearing microbiota and the epidemics of chronic diseases
10.1038/nri.2017.77 · 2017 · External reference
The ancestral and industrialized gut microbiota and implications for human health
10.1038/s41579-019-0191-8 · 2019 · External reference
