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References from E protein–driven iNKT subset modulation shapes early immune responses during influenza A virus infection. Local targets link to admitted publications; unresolved targets remain external evidence.
Estimates of US influenza-associated deaths made using four different methods
10.1111/j.1750-2659.2009.00073.x · 2009 · External reference
Invariant NKT cells modulate the suppressive activity of IL-10-secreting neutrophils differentiated with serum amyloid A
10.1038/ni.1942 · 2010 · External reference
Pivotal advance: invariant NKT cells reduce accumulation of inflammatory monocytes in the lungs and decrease immune-pathology during severe influenza a virus infection
10.1189/jlb.0411184 · 2012 · External reference
Potential role of invariant NKT cells in the control of pulmonary inflammation and CD8+ T cell response during acute influenza a virus H3N2 pneumonia
10.4049/jimmunol.1002348 · 2011 · External reference
Activation of invariant NKT cells enhances the innate immune response and improves the disease course in influenza A virus infection
10.1002/eji.200738017 · 2008 · External reference
New vaccines against influenza virus
10.7774/cevr.2014.3.1.12 · 2014 · External reference
Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity
10.1073/pnas.0813309106 · 2009 · External reference
Interleukin-22 is produced by invariant natural killer T lymphocytes during influenza A virus infection
10.1074/jbc.m111.304758 · 2012 · External reference
Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans
10.1172/jci36264 · 2008 · External reference
Group 2 innate lymphoid cell production of IL-5 is regulated by NKT cells during influenza virus infection
10.1371/journal.ppat.1003615 · 2013 · External reference
Heterosubtypic immunity to influenza A virus in mice lacking IgA, all Ig, NKT cells, or gamma delta T cells
10.4049/jimmunol.166.12.7437 · 2001 · External reference
The biology of NKT cells
10.1146/annurev.immunol.25.022106.141711 · 2007 · External reference
An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans
10.1084/jem.180.3.1097 · 1994 · External reference
NKT cells derive from double-positive thymocytes that are positively selected by CD1d
10.1038/ni710 · 2001 · External reference
YY1lo NKT cells are dedicated IL-10 producers
10.1038/s41598-020-60229-6 · 2020 · External reference
PLZF induces the spontaneous acquisition of memory/effector functions in T cells independently of NKT cell-related signals
10.4049/jimmunol.1000776 · 2010 · External reference
Unraveling natural killer T-cells development
10.3389/fimmu.2017.01950 · 2017 · External reference
Control points in NKT-cell development
10.1038/nri2116 · 2007 · External reference
IL-17-producing invariant NKT cells in lymphoid organs are recent thymic emigrants identified by neuropilin-1 expression
10.1182/blood-2011-01-329268 · 2011 · External reference
Activation of invariant NKT cells by toll-like receptor 9-stimulated dendritic cells requires type I interferon and charged glycosphingolipids
10.1016/j.immuni.2007.08.017 · 2007 · External reference
Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection
10.1084/jem.20102555 · 2011 · External reference
The role of invariant natural killer T cells in dendritic cell licensing, cross-priming, and memory CD8(+) T cell generation
10.3389/fimmu.2015.00379 · 2015 · External reference
Cytokine dependent and independent iNKT cell activation
10.1016/j.cyto.2010.04.016 · 2010 · External reference
Helix-loop-helix proteins in adaptive immune development
10.3389/fimmu.2022.881656 · 2022 · External reference
The function of E- and Id proteins in lymphocyte development
10.1038/35105060 · 2001 · External reference
Mutation of inhibitory helix-loop-helix protein Id3 causes γδ T-cell lymphoma in mice
10.1182/blood-2010-03-274506 · 2010 · External reference
Increased level of E protein activity during invariant NKT development promotes differentiation of invariant NKT2 and invariant NKT17 subsets
10.4049/jimmunol.1301546 · 2013 · External reference
E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation
10.4049/jimmunol.1302904 · 2014 · External reference
Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development
10.4049/jimmunol.1301521 · 2013 · External reference
The transcription factor PLZF directs the effector program of the NKT cell lineage
10.1016/j.immuni.2008.07.011 · 2008 · External reference
Balance between Id and E proteins regulates myeloid-versus-lymphoid lineage decisions
10.1182/blood-2008-06-164996 · 2009 · External reference
Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development
10.1016/j.immuni.2007.08.020 · 2007 · External reference
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages
10.1038/360225a0 · 1992 · External reference
IRF4-dependent dendritic cells regulate CD8+ T cell differentiation and memory responses in influenza infection
10.1038/s41385-019-0173-1 · 2019 · External reference
Interferon-β treatment reverses the detrimental effect of B-cell depletion therapy on respiratory virus infection
10.1093/jimmun/vkaf085 · External reference
Cytokine-mediated degradation of the transcription factor ERG impacts the pulmonary vascular response to systemic inflammatory challenge
10.1161/atvbaha.123.318926 · 2023 · External reference
Proteinase-activated receptor-1, CCL2, and CCL7 regulate acute neutrophilic lung inflammation
10.1165/rcmb.2013-0142oc · 2014 · External reference
Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: role of Cxcr2 activation and glycosaminoglycan interactions
10.1002/jlb.3a0820-207r · 2021 · External reference
Shared and distinct functions of type I and type III interferons
10.1016/j.immuni.2019.03.025 · 2019 · External reference
Integrative scATAC-seq and scRNA-seq analyses map thymic iNKT cell development and identify Cbfβ for its commitment
10.1038/s41421-023-00547-x · 2023 · External reference
Unresolved reference
External reference
Zeb2 regulates differentiation of long-lived effector of invariant natural killer T cells
10.1038/s42003-023-05421-w · 2023 · External reference
Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure
10.1038/s41467-021-21574-w · 2021 · External reference
Characterization of human invariant natural killer T cells expressing FoxP3
10.1093/intimm/dxr040 · 2011 · External reference
Clara cell secretory protein (CC16): characteristics and perspectives as lung peripheral biomarker
10.1046/j.1365-2222.2000.00760.x · 2000 · External reference
Unresolved reference
External reference
Lung fluid transport in aquaporin-5 knockout mice
10.1172/jci8258 · 2000 · External reference
RFX3 modulation of FOXJ1 regulation of cilia genes in the human airway epithelium
10.1186/1465-9921-14-70 · 2013 · External reference
Alveolar type 2 cells marker gene SFTPC inhibits epithelial-to-mesenchymal transition by upregulating SOX7 and suppressing WNT/β-catenin pathway in non-small cell lung cancer
10.3389/fonc.2024.1448379 · 2024 · External reference
Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity
10.1016/j.immuni.2009.08.001 · 2009 · External reference
Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1− invariant NKT cells to bacteria
10.4049/jimmunol.1002725 · 2011 · External reference
Intestinal Lin- c-kit+ NKp46- CD4- population strongly produces IL-22 upon IL-1β stimulation
10.4049/jimmunol.1201452 · 2013 · External reference
Tissue-specific functions of invariant natural killer T cells
10.1038/s41577-018-0034-2 · 2018 · External reference
Monocyte recruitment during infection and inflammation
10.1038/nri3070 · 2011 · External reference
Neutrophils in respiratory viral infections
10.1038/s41385-021-00397-4 · 2021 · External reference
Interferon-λ mediates non-redundant front-line antiviral protection against influenza virus infection without compromising host fitness
10.1016/j.immuni.2017.04.025 · 2017 · External reference
Cancer cells induce interleukin-22 production from memory CD4+ T cells via interleukin-1 to promote tumor growth
10.1073/pnas.1705165114 · 2017 · External reference
The role of interleukin-22 in lung health and its therapeutic potential for COVID-19
10.3389/fimmu.2022.951107 · 2022 · External reference
Interleukin-22: immunobiology and pathology
10.1146/annurev-immunol-032414-112123 · 2015 · External reference