Research graph
References from Real-world generalizability of sleep apnea–related polysomnographic metrics and their associations with clinical comorbidities. Local targets link to admitted publications; unresolved targets remain external evidence.
Adult obstructive sleep apnoea
10.1016/s0140-6736(13)60734-5 · 2014 · External reference
Obstructive sleep apnea: current perspectives
10.2147/nss.s124657 · 2018 · External reference
Metrics of sleep apnea severity: beyond the apnea-hypopnea index
10.1093/sleep/zsab030 · 2021 · External reference
Polysomnography indexes are discordant with quality of life, symptoms, and reaction times in sleep apnea patients
10.1016/j.otohns.2004.11.001 · 2005 · External reference
Sleepiness in patients with moderate to severe sleep-disordered breathing
10.1093/sleep/28.4.472 · 2005 · External reference
Prospective study of sleep-disordered breathing and hypertension: the Sleep Heart Health Study
10.1164/rccm.200712-1809oc · 2009 · External reference
Effect of obstructive sleep apnoea and its treatment with continuous positive airway pressure on the prevalence of cardiovascular events in patients with acute coronary syndrome (ISAACC study): a randomised controlled trial
10.1016/s2213-2600(19)30271-1 · 2020 · External reference
Blood pressure improvement with continuous positive airway pressure is independent of obstructive sleep apnea severity
10.5664/jcsm.3604 · 2014 · External reference
Effect of positive airway pressure on cardiovascular outcomes in coronary artery disease patients with nonsleepy obstructive sleep apnea. The RICCADSA randomized controlled trial
10.1164/rccm.201601-0088oc · 2016 · External reference
CPAP for prevention of cardiovascular events in obstructive sleep apnea
10.1056/nejmoa1606599 · 2016 · External reference
Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets
10.1164/rccm.201303-0448oc · 2013 · External reference
Upper-airway collapsibility and loop gain predict the response to oral appliance therapy in patients with obstructive sleep apnea
10.1164/rccm.201601-0099oc · 2016 · External reference
Loop gain predicts the response to upper airway surgery in patients with obstructive sleep apnea
10.1093/sleep/zsx094 · 2017 · External reference
Identifying obstructive sleep apnoea patients responsive to supplemental oxygen therapy
10.1183/13993003.00674-2018 · 2018 · External reference
Desipramine improves upper airway collapsibility and reduces OSA severity in patients with minimal muscle compensation
10.1183/13993003.00823-2016 · 2016 · External reference
Phenotypic approaches to obstructive sleep apnoea—new pathways for targeted therapy
10.1016/j.smrv.2016.12.003 · 2018 · External reference
Understanding phenotypes of obstructive sleep apnea: applications in anesthesia, surgery, and perioperative medicine
10.1213/ane.0000000000001546 · 2017 · External reference
Ventilatory control and airway anatomy in obstructive sleep apnea
10.1164/rccm.200404-510oc · 2004 · External reference
Pathophysiology underlying demographic and obesity determinants of sleep apnea severity
10.1513/annalsats.202203-271oc · 2023 · External reference
Sleep apnea physiological burdens and cardiovascular morbidity and mortality
10.1164/rccm.202209-1808oc · 2023 · External reference
Ventilatory burden as a measure of obstructive sleep apnea severity is predictive of cardiovascular and all-cause mortality
10.1164/rccm.202301-0109oc · 2023 · External reference
The hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the Osteoporotic Fractures In Men Study and the Sleep Heart Health Study
10.1093/eurheartj/ehy624 · 2019 · External reference
Physiologic consequences of upper airway obstruction in sleep apnea
10.1016/j.chest.2024.05.028 · 2024 · External reference
Quantifying the ventilatory control contribution to sleep apnoea using polysomnography
10.1183/09031936.00062914 · 2015 · External reference
Phenotyping pharyngeal pathophysiology using polysomnography in patients with obstructive sleep apnea
10.1164/rccm.201707-1435oc · 2018 · External reference
Quantifying the arousal threshold using polysomnography in obstructive sleep apnea
10.1093/sleep/zsx183 · 2018 · External reference
Within-night repeatability and long-term consistency of sleep apnea endotypes: the Multi-Ethnic Study of Atherosclerosis and Osteoporotic Fractures in Men
10.1093/sleep/zsac129 · 2022 · External reference
Research priorities for translating endo-phenotyping of adult obstructive sleep apnea to the clinic: an official American Thoracic Society Research Statement
10.1164/rccm.202507-1574st · 2025 · External reference
Sleep apnea endotypes: from the physiological laboratory to scalable polysomnographic measures
10.3389/frsle.2023.1188052 · 2023 · External reference
Associations between sleep apnea endotypes and comorbid diseases in a large clinical cohort
10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5248 · External reference
Racial/ethnic differences in sleep disturbances: the Multi-Ethnic Study of Atherosclerosis (MESA)
10.5665/sleep.4732 · 2015 · External reference
Unresolved reference
External reference
High-throughput multimodal automated phenotyping (MAP) with application to PheWAS
10.1093/jamia/ocz066 · 2019 · External reference
Mayo clinical Text Analysis and Knowledge Extraction System (cTAKES): architecture, component evaluation and applications
10.1136/jamia.2009.001560 · 2010 · External reference
Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data
10.1038/nbt.2749 · 2013 · External reference
Sleep apnea phenotyping and relationship to disease in a large clinical biobank
10.1093/jamiaopen/ooab117 · 2022 · External reference
10.1101/2025.07.30.25332466
10.1101/2025.07.30.25332466 · External reference
Finite-sample improved confidence intervals based on the estimating equation theory for the modified Poisson and least-squares regressions
10.1515/em-2024-0030 · 2025 · External reference
Regression shrinkage and selection via the lasso
10.1111/j.2517-6161.1996.tb02080.x · 1996 · External reference
Using the E-value to assess the potential effect of unmeasured confounding in observational studies
10.1001/jama.2018.21554 · 2019 · External reference
Sensitivity analysis in observational research: introducing the E-value
10.7326/m16-2607 · 2017 · External reference
Effect of weight loss on upper airway anatomy and the apnea-hypopnea index. The importance of tongue fat
10.1164/rccm.201903-0692oc · 2020 · External reference
Impact of obstructive sleep apnea on lung volumes and mechanical properties of the respiratory system in overweight and obese individuals
10.1186/s12890-015-0063-6 · 2015 · External reference
Contributions of upper airway mechanics and control mechanisms to severity of obstructive apnea
10.1164/rccm.200302-201oc · 2003 · External reference
Obstructive sleep apnea in older adults is a distinctly different physiological phenotype
10.5665/sleep.3844 · 2014 · External reference
Effect of age on EEG arousals in normal sleep
1998 · External reference
EEG arousal norms by age
10.5664/jcsm.26796 · 2007 · External reference
The association of body mass index values with severity and phenotype of sleep-disordered breathing
10.5578/tt.69057 · 2019 · External reference
The influence of sex on sleep characteristics in the adult and older adult population: findings from the EPISONO sleep study
10.3389/frsle.2025.1422169 · 2025 · External reference
Gender differences in the clinical and polysomnographic characteristics among Australian Aboriginal patients with obstructive sleep apnea
10.2147/nss.s258330 · 2020 · External reference
Sleep apnea and obstructive airway disease in older men: outcomes of Sleep Disorders in Older Men Study
10.5665/sleep.5960 · 2016 · External reference
