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References from Radioligand therapy for pediatric patients with solid tumors. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1016/b978-0-323-47674-4.00092-x
10.1016/b978-0-323-47674-4.00092-x · 2020 · External reference
Unresolved reference
2023 · External reference
Long-term survival and cure fraction estimates for childhood cancer in Europe (EUROCARE-6): results from a population-based study
10.1016/s1470-2045(22)00637-4 · 2022 · External reference
Chronic health conditions and neurocognitive function in aging survivors of childhood cancer: a report from the childhood cancer survivor study
10.1093/jnci/djx224 · 2018 · External reference
Medical care in long-term survivors of childhood cancer: a report from the childhood cancer survivor study
10.1200/jco.2008.16.9607 · 2008 · External reference
Radioligand therapy in cancer management: a global perspective
10.3390/cancers17213412 · 2025 · External reference
Gastroenteropancreatic neuroendocrine neoplasms: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
10.1016/j.annonc.2020.03.304 · 2020 · External reference
Phase 3 trial of 177 Lu-dotatate for midgut neuroendocrine tumors
10.1056/nejmoa1607427 · 2017 · External reference
Lutetium-177–PSMA-617 for metastatic castration-resistant prostate cancer
10.1056/nejmoa2107322 · 2021 · External reference
177Lu-PSMA-617 versus a change of androgen receptor pathway inhibitor therapy for taxane-naive patients with progressive metastatic castration-resistant prostate cancer (PSMAfore): a phase 3, randomised, controlled trial
10.1016/s0140-6736(24)01653-2 · 2024 · External reference
Hepatocellular carcinoma: ESMO clinical practice guideline for diagnosis, treatment and follow-up
10.1016/j.annonc.2025.02.006 · 2025 · External reference
The impact of radioactive iodine on outcomes among pediatric and adolescent thyroid cancer patients: a SEER database analysis
10.3390/cancers17010107 · 2025 · External reference
Theranostics for neuroblastoma: making molecular radiotherapy work better
10.2967/jnumed.124.269121 · 2025 · External reference
The current status and future potential of theranostics to diagnose and treat childhood cancer
10.3389/fonc.2020.578286 · 2020 · External reference
Biochemical diagnosis of catecholamine-producing tumors of childhood: neuroblastoma, pheochromocytoma and paraganglioma
10.3389/fendo.2022.901760 · 2022 · External reference
A narrative review of 35 years of meta-[131I]iodobenzylguanidine therapy in neuroblastoma
10.1016/j.ejcped.2024.100159 · 2024 · External reference
Treatment of advanced neuroblastoma: feasibility and therapeutic potential of a novel approach combining 131-I-MIBG and multiple drug chemotherapy
10.1054/bjoc.2000.1645 · 2001 · External reference
Conditioning regimens megatherapy combining I 131 metaiodobenzylguanidine and high-dose chemotherapy with haematopoietic progenitor cell rescue for neuroblastoma
10.1038/sj.bmt.1702846 · 2001 · External reference
Hematologic toxicity of high-dose iodine-131-metaiodobenzylguanidine therapy for advanced neuroblastoma
10.1200/jco.2004.08.058 · 2004 · External reference
Phase II study on the effect of disease sites, age, and prior therapy on response to iodine-131-metaiodobenzylguanidine therapy in refractory neuroblastoma
10.1200/jco.2006.09.3484 · 2007 · External reference
Iodine-131-metaiodobenzylguanidine double infusion with autologous stem-cell rescue for neuroblastoma: a new approaches to neuroblastoma therapy phase I study
10.1200/jco.2007.15.7628 · 2009 · External reference
I-131-Metaiodobenzylguanidine therapy with allogeneic cord blood stem cell transplantation for recurrent neuroblastoma
10.1186/1824-7288-38-53 · 2012 · External reference
Dose escalation study of no-carrier-added 131I-Metaiodobenzylguanidine for relapsed or refractory neuroblastoma: new approaches to neuroblastoma therapy consortium trial
10.2967/jnumed.111.098624 · 2012 · External reference
Upfront treatment of high-risk neuroblastoma with a combination of 131I-MIBG and topotecan
10.1002/pbc.25580;page:string:article/chapter · 2015 · External reference
Incorporation of high-dose 131I-metaiodobenzylguanidine treatment into tandem high-dose chemotherapy and autologous stem cell transplantation for high-risk neuroblastoma: results of the SMC NB-2009 study
10.1186/s13045-017-0477-0 · 2017 · External reference
Phase I/II clinical trial of high-dose [131I] meta-iodobenzylguanidine therapy for high-risk neuroblastoma preceding single myeloablative chemotherapy and haematopoietic stem cell transplantation
10.1007/s00259-021-05630-7 · 2022 · External reference
A systematic review of 131I-meta iodobenzylguanidine molecular radiotherapy for neuroblastoma
10.1016/j.ejca.2013.11.016 · 2014 · External reference
Phase I study of vincristine, irinotecan, and 131I-metaiodobenzylguanidine (131I-MIBG) for patients with relapsed or refractory neuroblastoma: a new approaches to neuroblastoma therapy (NANT) trial
10.1158/1078-0432.ccr-11-3201 · 2012 · External reference
Phase 1 study of vorinostat as a radiation sensitizer with 131I-metaiodobenzylguanidine (131I-MIBG) for patients with relapsed or refractory neuroblastoma
10.1158/1078-0432.ccr-14-3240 · 2015 · External reference
Pilot study of iodine-131-metaiodobenzylguanidine in combination with myeloablative chemotherapy and autologous stem-cell support for the treatment of neuroblastoma
10.1200/jco.2002.08.124 · 2002 · External reference
Phase I dose escalation of iodine-131-metaiodobenzylguanidine with myeloablative chemotherapy and autologous stem-cell transplantation in refractory neuroblastoma: a new approaches to neuroblastoma therapy consortium study
10.1200/jco.2005.03.6400 · 2006 · External reference
131I-Metaiodobenzylguanidine with intensive chemotherapy and autologous stem cell transplantation for high-risk neuroblastoma: a new approaches to neuroblastoma therapy (NANT) phase II study
10.1016/j.bbmt.2014.12.008 · 2015 · External reference
Feasibility of busulfan melphalan and stem cell rescue after 131 I-MIBG and topotecan therapy for refractory or relapsed metastatic neuroblastoma: the french experience
10.1097/mph.0000000000001137 · 2018 · External reference
Randomized phase II trial of MIBG versus MIBG, vincristine, and irinotecan versus MIBG and vorinostat for patients with relapsed or refractory neuroblastoma: a report from NANT consortium
10.1200/jco.21.00703 · 2021 · External reference
Phase II study of 131I-metaiodobenzylguanidine with 5 days of topotecan for refractory or relapsed neuroblastoma: results of the french study MIITOP
10.1002/pbc.30615 · 2023 · External reference
Phase I study of 131I-metaiodobenzylguanidine with dinutuximab ± vorinostat for patients with relapsed or refractory neuroblastoma: a new approaches to neuroblastoma therapy trial
10.1200/jco-24-02612 · 2025 · External reference
A safety and feasibility trial of 131I-MIBG in newly diagnosed high-risk neuroblastoma: a children’s oncology group study
10.1002/pbc.29117 · 2021 · External reference
Efficacy and safety of high-specific-activity 131I-MIBG therapy in patients with advanced pheochromocytoma or paraganglioma
10.2967/jnumed.118.217463 · 2019 · External reference
177Lu-DOTATATE molecular radiotherapy for childhood neuroblastoma
10.2967/jnumed.110.085100 · 2011 · External reference
Initial experience with gallium-68 DOTA-Octreotate PET/CT and peptide receptor radionuclide therapy for pediatric patients with refractory metastatic neuroblastoma
10.1097/mph.0000000000000411 · 2016 · External reference
A phase IIa trial of molecular radiotherapy with 177-lutetium DOTATATE in children with primary refractory or relapsed high-risk neuroblastoma
10.1007/s00259-020-04741-x · 2020 · External reference
A phase
10.3389/fped.2022.836230 · 2022 · External reference
Peptide receptor radionuclide therapy for metastatic paragangliomas
10.1007/s12032-016-0737-9 · 2016 · External reference
Challenging management of neuroendocrine tumor with hepatic metastasis and carcinoid heart disease in a child
10.1002/pbc.25993 · 2016 · External reference
Peptide receptor radionuclide therapy for treatment of metastatic neuroendocrine tumors in children
10.1002/pbc.29056 · 2021 · External reference
Safety and dosimetry of [177Lu]Lu-DOTA-TATE in adolescent patients with somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumours, or pheochromocytomas and paragangliomas: primary analysis of the phase II NETTER-P study
10.1007/s00259-025-07246-7 · 2025 · External reference
[18F]mFBG PET-CT for detection and localisation of neuroblastoma: a prospective pilot study
10.1007/s00259-022-06063-6 · 2023 · External reference
124I-MIBG PET/CT to monitor metastatic disease in children with relapsed neuroblastoma
10.2967/jnumed.120.243139 · 2021 · External reference
124I-MIBG: a new promising positron-emitting radiopharmaceutical for the evaluation of neuroblastoma
10.5603/nmr.2015.0024 · 2015 · External reference
Safety, biodistribution, and radiation dosimetry of 68Ga-OPS202 in patients with gastroenteropancreatic neuroendocrine tumors: a prospective phase I imaging study
10.2967/jnumed.117.199737 · 2018 · External reference
Sensitivity comparison of 68Ga-OPS202 and 68Ga-DOTATOC PET/CT in patients with gastroenteropancreatic neuroendocrine tumors: a prospective phase II imaging study
10.2967/jnumed.117.199760 · 2018 · External reference
A phase I/II study of the safety and efficacy of [177Lu]Lu-satoreotide tetraxetan in advanced somatostatin receptor-positive neuroendocrine tumours
10.1007/s00259-023-06383-1 · 2023 · External reference
Dosimetry and pharmacokinetics of [177Lu]Lu-satoreotide tetraxetan in patients with progressive neuroendocrine tumours
10.1007/s00259-024-06682-1 · 2024 · External reference
Preclinical development of [211At]meta-astatobenzylguanidine ([211At]MABG) as an alpha particle radiopharmaceutical therapy for neuroblastoma
10.1158/1078-0432.ccr-22-0400 · 2022 · External reference
Pre-clinical investigation of astatine-211-parthanatine for high-risk neuroblastoma
10.1038/s42003-022-04209-8 · 2022 · External reference
Targeted α-emitter therapy with 212Pb-DOTAMTATE for the treatment of metastatic SSTR-expressing neuroendocrine tumors: first-in-humans dose-escalation clinical trial
10.2967/jnumed.121.263230 · 2022 · External reference
Assessment of [225Ac]Ac-DOTATATE for targeted radioligand therapy in neuroblastoma
10.1016/j.jmir.2026.102231 · 2026 · External reference
Pediatric cancers: insights and novel therapeutic approaches
10.3390/cancers15143537 · 2023 · External reference
High-dose samarium-153 ethylene diamine tetramethylene phosphonate: low toxicity of skeletal irradiation in patients with osteosarcoma and bone metastases
10.1200/jco.2002.20.1.189 · 2002 · External reference
Gemcitabine radiosensitization after high-dose samarium for osteoblastic osteosarcoma
10.1158/1078-0432.ccr-05-0628 · 2005 · External reference
Dose-finding study of 153Sm-EDTMP in patients with poor-prognosis osteosarcoma
10.1002/cncr.24286 · 2009 · External reference
Tandem dosing of samarium-153 ethylenediamine tetramethylene phosphoric acid with stem cell support for patients with high-risk osteosarcoma
10.1002/cncr.25518 · 2010 · External reference
86 Re-HEDP in the treatment of patients with inoperable osteosarcoma
2006 · External reference
Alpha particle radium 223 dichloride in high-risk osteosarcoma: a phase I dose escalation trial
10.1158/1078-0432.ccr-18-3964 · 2019 · External reference
B7-H3 is widely expressed in soft tissue sarcomas
10.1186/s12885-024-13061-4 · 2024 · External reference
B7H3-Directed intraperitoneal radioimmunotherapy with radioiodinated omburtamab for desmoplastic small round cell tumor and other peritoneal tumors: results of a phase I study
10.1200/jco.20 · 2020 · External reference
223-Radium for metastatic osteosarcoma: combination therapy with other agents and external beam radiotherapy
10.1136/esmoopen-2019-000635 · 2020 · External reference
Oncotargets GD2 and GD3 are highly expressed in sarcomas of children, adolescents and young adults
10.1002/pbc.26097 · 2016 · External reference
Disialoganglioside GD2 expression in solid tumors and role as a target for cancer therapy
10.3389/fonc.2020.01000/full · 2020 · External reference
Recent clinical advances in fibroblast activation protein targeted radioligand therapy for solid tumors
10.3389/fnume.2025.1737443/text · 2025 · External reference
Pediatric brain tumors
10.1016/j.ncl.2018.04.009 · 2018 · External reference
Theranostics in neurooncology: heading toward new horizons
10.2967/jnumed.123.266205 · 2024 · External reference
Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma
10.1007/s11060-009-0038-7 · 2010 · External reference
Targeted radioimmunotherapy for embryonal tumor with multilayered rosettes
10.1007/s11060-019-03139-6 · 2019 · External reference
Central nervous system neuroblastoma metastases pseudoprogression following intraventricular anti-B7H3 radioimmunotherapy
10.1007/s11060-019-03203-1 · 2019 · External reference
Biodistribution and dosimetry of intraventricularly administered 124I-omburtamab in patients with metastatic leptomeningeal tumors
10.2967/jnumed.118.219576 · 2019 · External reference
Phase 1 study of intraventricular 131I-omburtamab targeting B7H3 (CD276)-expressing CNS malignancies
10.1186/s13045-022-01383-4 · 2022 · External reference
Outcomes of intraventricular 131-I-omburtamab and external beam radiotherapy in patients with recurrent medulloblastoma and ependymoma
10.1007/s11060-022-04235-w · 2023 · External reference
Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial
10.1016/s1470-2045(18)30322-x · 2018 · External reference
Phase 1 dose-escalation trial using convection-enhanced delivery of radio-immunotheranostic 124I-Omburtamab for diffuse intrinsic pontine glioma
10.1093/neuonc/noaf039 · 2025 · External reference
Targeted radioimmunotherapy for leptomeningeal cancer using 131I-3F8
10.1002/1096-911x(20001201)35:6<716::aid-mpo51>3.0.co;2-0 · 2000 · External reference
Phase I study of targeted radioimmunotherapy for leptomeningeal cancers using intra-Ommaya 131-I-3F8
10.1200/jco.2007.11.1807 · 2007 · External reference
A phase II study of radioimmunotherapy with intraventricular 131I-3F8 for medulloblastoma
10.1002/pbc.26754 · 2018 · External reference
Efficacy of high-dose chemotherapy or standard salvage therapy in patients with recurrent medulloblastoma
10.1215/15228517-2008-044 · 2008 · External reference
Results from a phase I study of 4-l-[131I]iodo-phenylalanine ([131I]IPA) with external radiation therapy in patients with recurrent glioblastoma (IPAX-1)
10.1093/noajnl/vdae130 · 2024 · External reference
[18F]FET-PET in children and adolescents with Central nervous system tumors: does it support difficult clinical decision-making?
10.1007/s00259-023-06114-6 · 2023 · External reference
Diagnostic accuracy and clinical impact of [18F]FET PET in childhood CNS tumors
10.1093/neuonc/noab096 · 2021 · External reference
Incidence trends and survival prediction of hepatoblastoma in children: a population-based study
10.1186/s40880-019-0411-7 · 2019 · External reference
Case of advanced hepatocellular carcinoma treated with transarterial radioembolization and subsequent liver transplantation in a 22-month-old
10.1097/mph.0000000000003152 · 2026 · External reference
Transarterial radioembolization with yttrium-90 of unresectable primary hepatic malignancy in children
10.1002/pbc.27510 · 2019 · External reference
Yttrium-90 transarterial radioembolization as a bridging therapy to liver transplant in a toddler with pretreatment extent (PRETEXT) IV hepatoblastoma
10.7759/cureus.87107 · 2025 · External reference
Transarterial radioembolization treatment as a bridge to surgical resection in pediatric hepatocellular carcinoma
10.1097/mph.0000000000002089 · 2021 · External reference
Trans-arterial radioembolization with yttrium-90 of unresectable and systemic chemotherapy resistant hepatoblastoma in three toddlers
10.1007/s00270-021-03026-6 · 2022 · External reference
Successful use of transarterial radioembolization with yttrium-90 (TARE-Y90) in two children with hepatoblastoma
10.1002/pbc.28421 · 2020 · External reference