Research graph
References from Comorbidity-specific molecular programmes of early diastolic dysfunction identify glucocorticoid receptor activation as a causal driver in obesity. Local targets link to admitted publications; unresolved targets remain external evidence.
Global epidemiology of heart failure
10.1038/s41569-024-01046-6 · 2024 · External reference
Evaluation and management of heart failure with preserved ejection fraction
10.1038/s41569-020-0363-2 · 2020 · External reference
Heart failure with preserved ejection fraction in humans and mice: embracing clinical complexity in mouse models
10.1093/eurheartj/ehab389 · 2021 · External reference
Association between renal function and cardiovascular structure and function in heart failure with preserved ejection fraction
10.1093/eurheartj/ehu254 · 2014 · External reference
Wild-type transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction
10.1093/eurheartj/ehv338 · 2015 · External reference
Teasing apart heart failure with preserved ejection fraction phenotypes with echocardiographic imaging: potential approach to research and clinical practice
10.1161/circresaha.117.312180 · 2018 · External reference
Clinical phenogroups in heart failure with preserved ejection fraction
10.1016/j.jchf.2019.09.009 · 2020 · External reference
Semaglutide in patients with heart failure with preserved ejection fraction and obesity
10.1056/nejmoa2306963 · 2023 · External reference
SGLT2 inhibitors in patients with heart failure: a comprehensive meta-analysis of five randomised controlled trials
10.1016/s0140-6736(22)01429-5 · 2022 · External reference
The future of heart failure diagnosis, therapy, and management
10.1161/circulationaha.116.023518 · 2016 · External reference
A simple, evidence-based approach to help guide diagnosis of heart failure with preserved ejection fraction
10.1161/circulationaha.118.034646 · 2018 · External reference
Unraveling comorbidities contribution to cardiac diastolic dysfunction and heart failure
10.1161/circheartfailure.124.011724 · 2025 · External reference
Central adiposity or hypertension
10.1016/j.jacc.2025.08.036 · 2025 · External reference
Calcineurin splicing variant calcineurin Aβ1 improves cardiac function after myocardial infarction without inducing hypertrophy
10.1161/circulationaha.110.012211 · 2011 · External reference
Overexpression of wild-type TMEM43 improves cardiac function in arrhythmogenic right ventricular cardiomyopathy type 5
10.1161/circresaha.124.325848 · 2025 · External reference
Protocol for single-nucleus transcriptomics of diploid and tetraploid cardiomyocytes in murine hearts
10.1016/j.xpro.2020.100049 · 2020 · External reference
Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data
10.1093/nar/gkp045 · 2009 · External reference
Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants
10.1038/s41467-020-19230-w · 2020 · External reference
Single-cell transcriptome atlas of murine endothelial cells
10.1016/j.cell.2020.01.015 · 2020 · External reference
Single-cell atlas of cardiac endothelial cell heterogeneity in pressure overload
10.1161/circresaha.125.327108 · 2026 · External reference
A naturally occurring calcineurin variant inhibits FoxO activity and enhances skeletal muscle regeneration
10.1083/jcb.200704179 · 2007 · External reference
Single-cell transcriptomics reveals cell-type-specific diversification in human heart failure
10.1038/s44161-022-00028-6 · 2022 · External reference
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function
10.1038/s41556-019-0446-7 · 2020 · External reference
Single-cell transcriptomics provides insights into hypertrophic cardiomyopathy
10.1016/j.celrep.2022.110809 · 2022 · External reference
A cross-study transcriptional patient map of heart failure defines conserved multicellular coordination in cardiac remodeling
10.1038/s41467-025-62219-6 · 2025 · External reference
Single-cell RNA sequencing reveals metabolic stress-dependent activation of cardiac macrophages in a model of dyslipidemia-induced diastolic dysfunction
10.1161/circulationaha.122.062984 · 2024 · External reference
Myeloid fatty acid metabolism activates neighboring hematopoietic stem cells to promote heart failure with preserved ejection fraction
10.1161/circulationaha.124.070248 · 2025 · External reference
The adipokine hypothesis of heart failure with a preserved ejection fraction
10.1016/j.jacc.2025.06.055 · 2025 · External reference
Conceptual models to explain heart failure with a preserved ejection fraction: a tale of futility, frustration, and perhaps, fruition
10.1161/circulationaha.125.078115 · 2026 · External reference
Mineralocorticoids, glucocorticoids, receptors and response elements
10.1126/science.8382375 · 1993 · External reference
Mineralocorticoid receptor antagonists in heart failure: a systematic review and meta-analysis
10.3389/fcvm.2025.1667236 · 2025 · External reference
Finerenone in heart failure with mildly reduced or preserved ejection fraction
10.1056/nejmoa2407107 · 2024 · External reference
