Research graph
References from Intensive blood-pressure control for the prevention of major cardiovascular events in stroke patients: rationale and design of the OPTIMAL-STROKE trial. Local targets link to admitted publications; unresolved targets remain external evidence.
Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the global burden of disease study 2021
10.1016/s1474-4422(24)00369-7 · 2024 · External reference
Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies
10.1016/s0140-6736(02)11911-8 · 2002 · External reference
Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis
10.1016/s0140-6736(15)01225-8 · 2016 · External reference
A randomized trial of intensive versus standard blood-pressure control
10.1056/nejmoa1511939 · 2015 · External reference
Trial of intensive blood-pressure control in older patients with hypertension
10.1056/nejmoa2111437 · 2021 · External reference
Effects of intensive blood-pressure control in type 2 diabetes mellitus
10.1056/nejmoa1001286 · 2010 · External reference
Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk with and without diabetes or previous stroke: an open-label, blinded-outcome, randomised trial
10.1016/s0140-6736(24)01028-6 · 2024 · External reference
Intensive blood-pressure control in patients with type 2 diabetes
10.1056/nejmoa2412006 · 2025 · External reference
Effectiveness of a non-physician community health-care provider-led intensive blood pressure intervention versus usual care on cardiovascular disease (CRHCP): an open-label, blinded-endpoint, cluster-randomised trial
10.1016/s0140-6736(22)02603-4 · 2023 · External reference
Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack
10.1016/s0140-6736(01)06178-5 · 2001 · External reference
Telmisartan to prevent recurrent stroke and cardiovascular events
10.1056/nejmoa0804593 · 2008 · External reference
Blood-pressure targets in patients with recent lacunar stroke: the SPS3 randomised trial
10.1016/s0140-6736(13)60852-1 · 2013 · External reference
Effect of standard vs intensive blood pressure control on the risk of recurrent stroke
10.1001/jamaneurol.2019.2167 · 2019 · External reference
Three low-dose antihypertensive agents in a single pill after intracerebral hemorrhage
10.1056/nejmoa2515043 · 2026 · External reference
2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on clinical practice guidelines
10.1161/hyp.0000000000000066 · 2018 · External reference
2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement
10.1097/hjh.0000000000002843 · 2021 · External reference
Unresolved reference
2021 · External reference
The win ratio: a new approach to the analysis of composite endpoints in clinical trials based on clinical priorities
10.1093/eurheartj/ehr352 · 2012 · External reference
Association between magnitude of differential blood pressure reduction and secondary stroke prevention
10.1001/jamaneurol.2023.0218 · 2023 · External reference
