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References from Congenital heart disease in adults: evolving health systems and lifelong outcomes. Local targets link to admitted publications; unresolved targets remain external evidence.
From lifespan to healthspan
10.1001/jama.2018.12621 · 2018 · External reference
Lifespan and healthspan: past, present, and promise
10.1093/geront/gnv130 · 2015 · External reference
Born to age: when adult congenital heart disease converges with geroscience
10.1016/j.jacadv.2022.100012 · 2022 · External reference
Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis
10.1016/j.jacc.2011.08.025 · 2011 · External reference
Global birth prevalence of congenital heart defects 1970-2017: updated systematic review and meta-analysis of 260 studies
10.1093/ije/dyz009 · 2019 · External reference
Temporal variation of birth prevalence of congenital heart disease in the United States
10.1111/chd.12176 · 2015 · External reference
Risk of congenital heart defects after ambient heat exposure early in pregnancy
10.1289/ehp171 · 2017 · External reference
Association between maternal chronic conditions and congenital heart defects: a population-based cohort study
10.1161/circulationaha.112.001054 · 2013 · External reference
Congenital malformations in Ecuadorian children: urgent need to create a national registry of birth defects
10.2147/tacg.s8794 · 2010 · External reference
Prevalence of congenital heart defects in Europe, 2008-2015: a registry-based study
10.1002/bdr2.2117 · 2022 · External reference
Descriptive epidemiology of congenital heart disease in Northern England
10.1111/j.1365-3016.2008.00987.x · 2009 · External reference
National time trends in congenital heart defects, Denmark, 1977-2005
10.1016/j.ahj.2008.10.017 · 2009 · External reference
Congenital heart defects and indices of placental and fetal growth in a nationwide study of 924 422 liveborn infants
10.1161/circulationaha.116.021793 · 2016 · External reference
Trends in the prevalences of congenital anomalies and age at motherhood in a Southern European region: a population-based study
10.1136/bmjopen-2013-004244 · 2014 · External reference
Epidemiological characterization of congenital heart disease in Sao Miguel Island, Azores, Portugal
10.1159/000091488 · 2006 · External reference
The congenital malformations in children aged 0-2 in Zielona Góra province (1988-1997) and Lubuskie province (1998-2007) according to the Polish registry of congenital malformations. Part 3. Age of mother and frequency of congenital malformations in children
10.1016/j.pepo.2012.10.001 · 2013 · External reference
[Prevalence, mortality and lethality of congenital heart defects from the Tuscan registry (Tuscany Region, Central Italy), 1992-2009]
2015 · External reference
[The incidence and diagnostics of congenital heart defects in Kaunas infant population during 1999-2005]
10.3390/medicina44020018 · 2008 · External reference
Distribution of congenital heart disease in Croatia and outcome analysis. A Croatian epidemiological study (2002-2007)
2011 · External reference
Congenital heart disease: changes in recorded birth prevalence and cardiac interventions over the past half-century in Sweden
10.1093/eurjpc/zwac227 · 2023 · External reference
Birth prevalence of congenital heart disease in China, 1980–2019: a systematic review and meta-analysis of 617 studies
10.1007/s10654-020-00653-0 · 2020 · External reference
Spatial distribution and birth prevalence of congenital heart disease in Iran: a systematic review and hierarchical Bayesian meta-analysis
10.34172/ijhpm.2024.7931 · 2024 · External reference
The burden of congenital heart disease in Malaysia: a comprehensive review and meta-analytic synthesis, 1970–2024
10.1186/s12889-025-23800-2 · 2025 · External reference
Prevalence of congenital malformations and genetic diseases in Korea
10.1007/s100380050102 · 1999 · External reference
Accuracy of congenital anomaly coding in live birth children recorded in European health care databases, a EUROlinkCAT study
10.1007/s10654-023-00971-z · 2023 · External reference
Variation of prenatal detection of congenital heart disease in infants: updated analysis of The Society of Thoracic Surgeons Congenital Heart Surgery database
10.1016/j.athoracsur.2025.06.049 · 2026 · External reference
Global, regional, and national epidemiology of congenital birth defects in children from 1990 to 2021: a cross-sectional study
10.1186/s12884-025-07612-1 · 2025 · External reference
Burden of fetal anomalies among antenatal mothers attending a public referral hospital: a mixed cohort study
10.25259/ijma_44_2024 · 2025 · External reference
Congenital heart disease in the general population: changing prevalence and age distribution
10.1161/circulationaha.106.627224 · 2007 · External reference
Changing landscape of congenital heart disease
10.1161/circresaha.116.309302 · 2017 · External reference
Survivorship in children and young adults with congenital heart disease in Sweden
10.1001/jamainternmed.2016.7765 · 2017 · External reference
Changing mortality in congenital heart disease
10.1016/j.jacc.2010.03.085 · 2010 · External reference
Mortality associated with adult congenital heart disease: trends in the US population from 1979 to 2005
10.1016/j.ahj.2009.08.014 · 2009 · External reference
Lesion-specific congenital heart disease mortality trends in children: 1999 to 2017
10.1542/peds.2022-056294 · 2022 · External reference
Longitudinal trends in pediatric survival by congenital heart defect in Texas, 1999 to 2017
10.1016/j.jacadv.2025.101812 · 2025 · External reference
Global, regional, and national burden of congenital heart disease, 1990-2017: a systematic analysis for the global burden of disease study 2017
10.1016/s2352-4642(19)30402-x · 2020 · External reference
Unresolved reference
2024 · External reference
Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: comparison between low-income and high-income countries
10.1016/s0140-6736(06)68337-2 · 2006 · External reference
Unresolved reference
2022 · External reference
Recommendations for developing effective and safe paediatric and congenital heart disease services in low-income and middle-income countries: a public health framework
10.1136/bmjgh-2023-012049 · 2023 · External reference
Trends in burden and mortality of congenital birth defects in G20 countries (1990-2021) and predictions for 2022-2040
10.1186/s12884-025-07617-w · 2025 · External reference
Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050
10.3389/fped.2025.1601620 · 2025 · External reference
Long-term outcomes of the arterial switch operation
10.1016/j.jtcvs.2021.01.134 · 2022 · External reference
Lifetime prevalence of congenital heart disease in the general population from 2000 to 2010
10.1161/circulationaha.113.008396 · 2014 · External reference
Projected growth of the adult congenital heart disease population in the United States to 2050: an integrative systems modeling approach
10.1186/s12963-015-0063-z · 2015 · External reference
Adult congenital heart disease in a nationwide population 2000-2014: epidemiological trends, arrhythmia, and standardized mortality ratio
10.1161/jaha.117.007907 · 2018 · External reference
Prevalence of adult patients with congenital heart disease in Japan
10.1016/j.ijcard.2009.05.032 · 2011 · External reference
Changing epidemiology of congenital heart disease: effect on outcomes and quality of care in adults
10.1038/s41569-022-00749-y · 2023 · External reference
Quality of life of adults with congenital heart disease in 15 countries: evaluating country-specific characteristics
10.1016/j.jacc.2016.03.477 · 2016 · External reference
Wellbeing in children and adolescents with Fontan physiology
10.1016/j.jpeds.2024.114156 · 2024 · External reference
Clinical risk assessment and prediction in congenital heart disease across the lifespan: JACC scientific statement
10.1016/j.jacc.2024.02.055 · 2024 · External reference
The care of adults with congenital heart disease across the globe: current assessment and future perspective: a position statement from the International Society for Adult Congenital Heart Disease (ISACHD)
10.1016/j.ijcard.2015.04.230 · 2015 · External reference
The future of adult congenital heart disease research: precision health services delivery for the next decade
10.1016/j.cjca.2019.09.015 · 2019 · External reference
Trajectories of care in congenital heart disease–the long arm of disease in the womb
10.1111/joim.13048 · 2020 · External reference
Improving long-term care and outcomes of congenital heart disease: fulfilling the promise of a healthy life
10.1016/s2352-4642(23)00053-6 · 2023 · External reference
Toward providing equitable care for adults with congenital heart disease: where we are and where we need to be
10.1007/s11886-025-02307-7 · 2025 · External reference
Adults with congenital heart disease: trends in event-free survival past middle age
10.1161/circulationaha.122.060834 · 2023 · External reference
Geriatric congenital heart disease: a new challenge in the care of adults with congenital heart disease?
10.1093/eurheartj/eht358 · 2014 · External reference
Adult congenital heart disease survivors at age 50 years: medical and psychosocial Status
10.1016/j.hlc.2020.05.114 · 2021 · External reference
The burden of cardiovascular risk factors among seniors with congenital heart disease: a single tertiary center experience
10.33963/kp.a2021.0129 · 2021 · External reference
Geriatric congenital heart disease: burden of disease and predictors of mortality
10.1016/j.jacc.2011.06.041 · 2011 · External reference
Lifespan perspective on congenital heart disease research: JACC state-of-the-art review
10.1016/j.jacc.2021.03.012 · 2021 · External reference
Adult congenital heart disease
10.1161/circulationaha.123.066983 · 2024 · External reference
Critical care of the adult with congenital heart disease
10.1016/j.jacadv.2025.102081 · 2025 · External reference
Risk prediction models for heart failure admissions in adults with congenital heart disease
10.1016/j.ijcard.2020.08.039 · 2021 · External reference
Heart failure admissions in adults with congenital heart disease; risk factors and prognosis
10.1016/j.ijcard.2013.03.003 · 2013 · External reference
Incidence and outcomes of advanced heart failure in adults with congenital heart disease
10.1161/circheartfailure.122.009675 · 2022 · External reference
Atrial arrhythmias in adults with congenital heart disease
10.1161/circulationaha.109.866319 · 2009 · External reference
Arrhythmias in congenitally corrected transposition of the great arteries: an international study
10.1093/eurheartj/ehaf466 · 2026 · External reference
Mechanisms, prevention, and treatment of atrial fibrillation after cardiac surgery
10.1016/j.jacc.2007.10.043 · 2008 · External reference
Sudden cardiac death in congenital heart disease
10.1093/eurheartj/ehac104 · 2022 · External reference
Sudden cardiac death in adult congenital heart disease: can the unpredictable be foreseen?
10.1093/europace/euw060 · 2017 · External reference
Sudden cardiac death in adult congenital heart disease
10.1161/circulationaha.112.104786 · 2012 · External reference
Predicting sudden cardiac death in adults with congenital heart disease
10.1136/heartjnl-2020-316791 · 2021 · External reference
Impaired cardiac autonomic nervous activity predicts sudden cardiac death in patients with operated and unoperated congenital cardiac disease
10.1016/j.jtcvs.2006.03.057 · 2006 · External reference
Contemporary prevalence of pulmonary arterial hypertension in adult congenital heart disease following the updated clinical classification
10.1016/j.ijcard.2014.04.072 · 2014 · External reference
Status of adult outpatients with congenital heart disease in Japan: the Japanese network of cardiovascular departments for adult congenital heart disease registry
10.1016/j.jjcc.2022.07.019 · 2022 · External reference
Pulmonary hypertension in adult congenital heart disease in Asia: a distinctive feature of Complex congenital heart disease
10.1161/jaha.121.022596 · 2022 · External reference
Stroke in adults with congenital heart disease: incidence, cumulative risk, and predictors
10.1161/circulationaha.115.011241 · 2015 · External reference
Risk of dementia in adults with congenital heart disease: population-based cohort study
10.1161/circulationaha.117.029686 · 2018 · External reference
Neurocognitive disorders amongst patients with congenital heart disease undergoing procedures in childhood
10.1016/j.ijcard.2021.05.001 · 2021 · External reference
Abnormal brain development in newborns with congenital heart disease
10.1056/nejmoa067393 · 2007 · External reference
Cognitive deficits and associated neurological complications in individuals with Down's syndrome
10.1016/s1474-4422(10)70112-5 · 2010 · External reference
Heart failure and risk of dementia: a Danish nationwide population-based cohort study
10.1002/ejhf.631 · 2017 · External reference
Long-term risk of dementia among survivors of ischemic or hemorrhagic stroke
10.1161/strokeaha.116.015242 · 2017 · External reference
Measures of exercise capacity in adults with congenital heart disease
10.1016/j.ijcard.2010.08.030 · 2011 · External reference
Cardiovascular and cognitive fitness at age 18 and risk of early-onset dementia
10.1093/brain/awu041 · 2014 · External reference
Prevalence of metabolic syndrome in young adults with congenital heart disease
10.1016/j.amjcard.2022.05.031 · 2022 · External reference
Metabolic syndrome in adults with congenital heart disease
10.1161/jaha.114.001132 · 2016 · External reference
Prognosis of chronic kidney disease and metabolic syndrome in adults with congenital heart disease
10.3346/jkms.2023.38.e375 · 2023 · External reference
Congenital heart disease with and without cyanotic potential and the long-term risk of diabetes Mellitus: a population-based follow-up study
10.1161/jaha.115.003076 · 2016 · External reference
Chronic kidney disease in patients with congenital heart disease: a nationwide, register-based cohort study
10.1093/ehjopen/oeac055 · 2022 · External reference
Prevalence, predictors, and prognostic value of renal dysfunction in adults with congenital heart disease
10.1161/circulationaha.107.734921 · 2008 · External reference
Chronic kidney disease in congenital heart disease patients: a narrative review of evidence
10.1186/s40697-015-0063-8 · 2015 · External reference
Prevalence of cancer in adults with congenital heart disease compared with the general population
10.1016/j.amjcard.2016.08.057 · 2016 · External reference
The risk of cancer in patients with congenital heart disease: a nationwide population-based cohort study in Taiwan
10.1371/journal.pone.0116844 · 2015 · External reference
Risk of Cancer among children and young adults with congenital heart disease compared with healthy controls
10.1001/jamanetworkopen.2019.6762 · 2019 · External reference
Exposure to low-dose ionizing radiation from cardiac procedures and malignancy risk in adults with congenital heart disease
10.1161/circulationaha.117.029138 · 2018 · External reference
Flexible modeling of the association between cumulative exposure to low-dose ionizing radiation from cardiac procedures and risk of cancer in adults with congenital heart disease
10.1093/aje/kwz114 · 2019 · External reference
CanCHD study of hematopoietic cancers in children with and without genetic syndromes
10.1161/jaha.122.026604 · 2024 · External reference
Anxiety and depression in adults with congenital heart disease
10.1016/j.jacc.2023.10.043 · 2024 · External reference
Post-traumatic stress disorder, anxiety, and depression among adults with congenital heart defects
10.1002/bdr2.1971 · 2022 · External reference
Prevalence and prognostic association of a clinical diagnosis of depression in adult congenital heart disease: results of the Boston adult congenital heart disease biobank
10.1161/jaha.119.014820 · 2020 · External reference
Prevalence and correlates of post-traumatic stress disorder in adults with congenital heart disease
10.1016/j.amjcard.2015.11.065 · 2016 · External reference
Characteristics of adults with congenital heart defects in the United States
10.1016/j.jacc.2020.05.025 · 2020 · External reference
Neurocognitive impairment and its long-term impact on adults with congenital heart disease
10.1016/j.pcad.2018.08.002 · 2018 · External reference
Canadian Cardiovascular Society 2022 guidelines for cardiovascular interventions in adults with congenital heart disease
10.1016/j.cjca.2022.03.021 · 2022 · External reference
Life's essential 8: updating and enhancing the American Heart Association's construct of cardiovascular health: a presidential advisory from the American Heart Association
10.1161/cir.0000000000001078 · 2022 · External reference
Part 1: quality of care–what is it?
10.1056/nejm199609193351213 · 1996 · External reference
Toronto ACHD program: a 65 year legacy
10.1016/j.ijcchd.2024.100563 · 2025 · External reference
Unresolved reference
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Unresolved reference
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Adult congenital heart disease care in Canada: has quality of care improved in the last decade?
10.1016/j.cjca.2023.08.004 · 2024 · External reference
Recommendations for organization of care for adults with congenital heart disease and for training in the subspecialty of ‘grown-up congenital heart disease’ in Europe: a position paper of the working group on grown-up congenital heart disease of the European Society of Cardiology
10.1093/eurheartj/eht572 · 2014 · External reference
Adult congenital heart disease training in Europe: current status, disparities and potential solutions
10.1136/openhrt-2023-002558 · 2023 · External reference
Adult congenital heart disease in Australia and New Zealand: a call for optimal care
10.1016/j.hlc.2018.10.015 · 2019 · External reference
Unresolved reference
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Unresolved reference
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Position statement for the development of adult congenital heart disease units in Latin America and the Caribbean: recommendations by the adult congenital heart disease chapter and pediatric cardiology council of the interamerican society of cardiology
10.1016/j.ijcchd.2023.100461 · 2023 · External reference
Care of the adult with congenital heart disease: introduction
10.1016/s0735-1097(01)01280-3 · 2001 · External reference
Planning the specialized care of adult congenital heart disease patients: from numbers to guidelines; an epidemiologic approach
10.1016/j.ahj.2008.08.029 · 2009 · External reference
Staffing, activities, and infrastructure in 96 specialised adult congenital heart disease clinics in Europe
10.1016/j.ijcard.2019.04.077 · 2019 · External reference
Adult congenital heart disease: report from a public reference hospital in Northeastern Brazil
10.21470/1678-9741-2023-0039 · 2023 · External reference
2020 ESC guidelines for the management of adult congenital heart disease
10.1093/eurheartj/ehaa554 · 2021 · External reference
2025 ACC/AHA/HRS/ISACHD/SCAI guideline for the management of adults with congenital heart disease: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines
10.1016/j.jacc.2025.09.006 · 2026 · External reference
The use of personal digital assistants in clinical decision making by health care professionals: a systematic review
10.1177/1460458212446761 · 2013 · External reference
Unresolved reference
2025 · External reference
Specialized adult congenital heart disease care: the impact of policy on mortality
10.1161/circulationaha.113.005817 · 2014 · External reference
The future of adult congenital heart care in the United States: are we keeping up with the pace of progress?
10.1016/j.jacc.2025.12.076 · 2026 · External reference
2018 AHA/ACC guideline for the management of adults with congenital heart disease: a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines
10.1161/cir.0000000000000603 · 2019 · External reference
TeleHealth networks: instant messaging and point-to-point communication over the internet
10.1016/j.nima.2006.08.147 · 2006 · External reference
Structure and activities of adult congenital heart disease programmes in Europe
10.1093/eurheartj/ehp551 · 2010 · External reference
Nurse specialists in adult congenital heart disease: the current status in Europe
10.1016/j.ejcnurse.2005.10.010 · 2006 · External reference
Chronic heart failure in congenital heart disease: a scientific statement from the American Heart Association
10.1161/cir.0000000000000352 · 2016 · External reference
Telemedicine in adult congenital heart disease: usefulness of digital health technology in the assistance of critical patients
10.3390/ijerph20105775 · 2023 · External reference
Adult congenital heart disease telemedicine and future directions
10.1016/j.jaccas.2021.04.005 · 2021 · External reference
Artificial intelligence in congenital heart disease: current state and prospects
10.1016/j.jacadv.2022.100153 · 2022 · External reference
The congenital cardiology cloud - optimizing long-term care by connecting ambulatory and hospital medical attendance via telemedicine
10.1055/a-2154-6659 · 2024 · External reference
Building quality indicators to improve care for adults with congenital heart disease
10.1016/j.jacc.2013.07.099 · 2013 · External reference
A framework of deep learning networks provides expert-level accuracy for the detection and prognostication of pulmonary arterial hypertension
10.1093/ehjci/jeac147 · 2022 · External reference
Machine learning algorithms estimating prognosis and guiding therapy in adult congenital heart disease: data from a single tertiary centre including 10 019 patients
10.1093/eurheartj/ehy915 · 2019 · External reference
Deep learning in medicine
10.1016/j.jacadv.2022.100017 · 2022 · External reference
The European health data space can be a boost for research beyond borders
10.1038/s41591-024-03246-6 · 2024 · External reference
Beyond atrial fibrillation: machine learning algorithm predicts stroke in adult patients with congenital heart disease
10.1016/j.mcpdig.2023.12.002 · 2024 · External reference
Electrocardiogram-based deep learning to predict mortality in paediatric and adult congenital heart disease
10.1093/eurheartj/ehae651 · 2025 · External reference
Early hybrid cardiac rehabilitation in congenital heart disease: the QUALIREHAB trial
10.1093/eurheartj/ehae085 · 2024 · External reference
Children's experiences of congenital heart disease: a systematic review of qualitative studies
10.1007/s00431-017-3081-y · 2018 · External reference
Recommendations for advance care planning in adults with congenital heart disease: a position paper from the ESC working group of adult congenital heart disease, the Association of Cardiovascular Nursing and Allied Professions (ACNAP), the European Association for Palliative Care (EAPC), and the International Society for Adult Congenital Heart Disease (ISACHD)
10.1093/eurheartj/ehaa614 · 2020 · External reference
Meaningful patient and public involvement in digital health innovation, implementation and evaluation: a systematic review
10.1111/hex.13506 · 2022 · External reference