Research graph
References from Deep vein thrombosis exacerbated by syndecan-4 shedding and piezo1-dependent endothelial-mesenchymal transition. Local targets link to admitted publications; unresolved targets remain external evidence.
Deep vein thrombosis and pulmonary embolism
10.1016/s0140-6736(16)30514-1 · 2016 · External reference
Epidemiology of deep vein thrombosis
10.1024/0301-1526/a001145 · 2024 · External reference
Venous thromboembolism
10.1016/s0140-6736(20)32658-1 · 2021 · External reference
Venous thromboembolism mortality and trends in older US adults, 2011–2019
10.1002/ajh.26996 · 2023 · External reference
Metabolic pathways in deep vein thrombosis: a new frontier for therapeutic intervention
10.1182/blood.2024027636 · 2025 · External reference
Venous thromboembolism: advances in diagnosis and treatment
10.1001/jama.2018.14346 · 2018 · External reference
Deep vein thrombosis
10.1136/bmj.k351 · 2018 · External reference
Endothelial cell-mediated venous thrombosis
10.1182/blood.2022017938 · 2022 · External reference
Thrombosis and platelets: an update
10.1093/eurheartj/ehw550 · 2017 · External reference
A comprehensive review of risk factors for venous thromboembolism: from epidemiology to pathophysiology
10.3390/ijms24043169 · 2023 · External reference
The pathogenesis of cancer-associated thrombosis
10.1007/s12185-024-03735-x · 2024 · External reference
Endothelial to mesenchymal transition: at the axis of cardiovascular health and disease
10.1093/cvr/cvae021 · 2024 · External reference
Endothelial to mesenchymal transition in health and disease
10.1146/annurev-physiol-032222-080806 · 2023 · External reference
Principal mode of Syndecan-4 mechanotransduction for the endothelial glycocalyx is a scissor-like dimer motion
10.1111/apha.13376 · 2020 · External reference
Roles of Syndecan-4 in cardiac injury and repair
10.1016/j.biocel.2022.106196 · 2022 · External reference
Syndecan-4 shedding impairs macrovascular angiogenesis in diabetes mellitus
10.1016/j.bbrc.2016.03.112 · 2016 · External reference
MMP-9 mediated Syndecan-4 shedding correlates with osteoarthritis severity
10.1016/j.joca.2020.10.009 · 2021 · External reference
Syndecan 4 is a marker of endothelial inflammation in pathological aging and predicts long-term cardiovascular outcomes in type 2 diabetes
10.1186/s13098-024-01431-8 · 2024 · External reference
Shed syndecan-4 and its possible roles in osteoarthritis
10.3390/biomedicines13051037 · 2025 · External reference
Protein kinase C (PKC) delta regulates PKCalpha activity in a Syndecan-4-dependent manner
10.1074/jbc.m202501200 · 2002 · External reference
RANTES/CCL5 mediated-biological effects depend on the syndecan-4/PKCα signaling pathway
10.1242/bio.20148227 · 2014 · External reference
Andrographolide targets syndecan4 to impair its interaction with syntenin and inhibits the biogenesis of small extracellular vesicles
10.1016/j.jbc.2026.111182 · 2026 · External reference
Single-cell RNA sequencing reveals endothelial cell heterogeneity and Sox18-mediated EndMT in abdominal aortic aneurysm
10.7150/thno.110254 · 2025 · External reference
ANGPTL4 prevents atherosclerosis by preserving KLF2 to suppress EndMT and mitigates endothelial dysfunction
10.1161/atvbaha.125.322700 · 2025 · External reference
GDF15 affects venous thrombosis by promoting EndMT through smad2/p-smad2 pathway
10.1186/s12959-023-00547-7 · 2023 · External reference
Semaphorin 7A promotes endothelial to mesenchymal transition through ATF3 mediated TGF-β2/Smad signaling
10.1038/s41419-020-02818-x · 2020 · External reference
Force-induced conformational changes in PIEZO1
10.1038/s41586-019-1499-2 · 2019 · External reference
Piezo1 senses pressure overload and initiates cardiac hypertrophy
10.1038/s41569-022-00746-1 · 2022 · External reference
EPHB4-RASA1 inhibition of PIEZO1 ras activation drives lymphatic valvulogenesis
10.1161/circresaha.124.325383 · 2024 · External reference
VE-PTP inhibition elicits eNOS phosphorylation to blunt endothelial dysfunction and hypertension in diabetes
10.1093/cvr/cvaa213 · 2021 · External reference
Ion channel Piezo1 activation aggravates the endothelial dysfunction under a high glucose environment
10.1186/s12933-024-02238-7 · 2024 · External reference
Alteration of Piezo1 signaling in type 2 diabetic mice: focus on endothelium and BK(Ca) channel
10.1007/s00424-024-02983-4 · 2024 · External reference
Force sensing by piezo channels in cardiovascular health and disease
10.1161/atvbaha.119.313348 · 2019 · External reference
Targeting the tyrosine kinase Src in endothelium attenuates inflammation and atherogenesis induced by disturbed flow
10.1111/bph.17307 · 2025 · External reference
Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure
10.1172/jci123825 · 2019 · External reference
Piezo1-mediated mechanotransduction contributes to disturbed flow-induced atherosclerotic endothelial inflammation
10.1161/jaha.123.035558 · 2024 · External reference
Piezo1 activation accelerates osteoarthritis progression and the targeted therapy effect of artemisinin
10.1016/j.jare.2023.09.040 · 2024 · External reference
Mechanosensing by Piezo1 and its implications for physiology and various pathologies
10.1111/brv.12814 · 2022 · External reference
Piezo1 specific deletion in endothelial cell protects the progression of pulmonary fibrosis in mice
10.1186/s12964-026-02758-7 · 2026 · External reference
Uncoupling the vicious cycle of mechanical stress and inflammation in calcific aortic valve disease
10.3389/fcvm.2022.783543 · 2022 · External reference
