Research graph
References from The SOS response acts as a regulatory switch that balances helicase anti-recombination with transcription–replication conflict resolution activities in Escherichia coli. Local targets link to admitted publications; unresolved targets remain external evidence.
Mechanism of quinolone action and resistance
10.1021/bi5000564 · 2014 · External reference
Hyper-recombination in uvrD mutants of Escherichia coli K-12
10.1007/bf00267368 · 1980 · External reference
Localization of an accessory helicase at the replisome is critical in sustaining efficient genome duplication
10.1093/nar/gkq889 · 2011 · External reference
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection
10.1038/msb4100050 · 2006 · External reference
Definitions and guidelines for research on antibiotic persistence
10.1038/s41579-019-0196-3 · 2019 · External reference
Reca: regulation and mechanism of a molecular search engine
10.1016/j.tibs.2016.04.002 · 2016 · External reference
Uvrd mutations enhance tandem repeat deletion in the Escherichia coli chromosome via SOS induction of the RecF recombination pathway
10.1046/j.1365-2958.1997.6011973.x · 1997 · External reference
Nonoptimal microbial response to antibiotics underlies suppressive drug interactions
10.1016/j.cell.2009.10.025 · 2009 · External reference
The helicases DinG, rep and UvrD cooperate to promote replication across transcription units in vivo
10.1038/emboj.2009.308 · 2010 · External reference
Suppression of genetic defects within the RAD6 pathway by srs2 is specific for error-free post-replication repair but not for damage-induced mutagenesis
10.1093/nar/30.3.732 · 2002 · External reference
Accessory replicative helicases and the replication of protein-bound DNA
10.1016/j.jmb.2014.10.001 · 2014 · External reference
Uvrd limits the number and intensities of RecA-green fluorescent protein structures in Escherichia coli K-12
10.1128/jb.01777-06 · 2007 · External reference
Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli
10.1093/genetics/158.1.41 · 2001 · External reference
Nalidixic acid: an antibacterial paradox
10.1128/aac.8.3.251 · 1975 · External reference
Non-equilibrium repressor binding kinetics link DNA damage dose to transcriptional timing within the SOS gene network Matic I, editor
10.1371/journal.pgen.1007405 · 2018 · External reference
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
10.1073/pnas.120163297 · 2000 · External reference
Superfamily I helicases as modular components of DNA-processing machines
10.1042/bst0390413 · 2011 · External reference
DNA gyrase, topoisomerase IV, and the 4-quinolones
10.1128/mmbr.61.3.377-392.1997 · 1997 · External reference
Break-induced replication promotes formation of lethal joint molecules dissolved by Srs2
10.1038/s41467-017-01987-2 · 2017 · External reference
Alternate pathways involving Sgs1/Top3, Mus81/Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication
10.1073/pnas.252652399 · 2002 · External reference
Mazf endoribonuclease promotes resolution of transcription–replication conflicts at ribosomal RNA genes in Escherichia coli
10.1093/nar/gkaf1034 · 2025 · External reference
rRNA operon multiplicity as a bacterial genome stability insurance policy
10.1093/nar/gkac332 · 2022 · External reference
Determinants of base-pair substitution patterns revealed by whole-genome sequencing of DNA mismatch repair defective Escherichia coli
10.1534/genetics.118.301237 · 2018 · External reference
Transcription–replication conflicts: how they occur and how they are resolved
10.1038/nrm.2016.88 · 2016 · External reference
Isolation and characterization of an operator-constitutive mutation in the recA gene of E. coli K-12
10.1007/bf00384376 · 1982 · External reference
Rep provides a second motor at the replisome to promote duplication of protein-bound DNA
10.1016/j.molcel.2009.11.009 · 2009 · External reference
Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria
10.1093/femsre/fux010 · 2017 · External reference
Recq DNA helicase is a suppressor of illegitimate recombination in Escherichia coli
10.1073/pnas.94.8.3860 · 1997 · External reference
Direct removal of RNA polymerase barriers to replication by accessory replicative helicases
10.1093/nar/gkz170 · 2019 · External reference
Functions that protect Escherichia coli from tightly bound DNA-protein complexes created by mutant EcoRII methyltransferase Sandler SJ, editor
10.1371/journal.pone.0128092 · 2015 · External reference
Damage signaling: RecQ sends an SOS to you
10.1016/j.cub.2004.09.073 · 2004 · External reference
Role of the Escherichia coli RecQ DNA helicase in SOS signaling and genome stabilization at stalled replication forks
10.1101/gad.1223804 · 2004 · External reference
Uvrd helicase suppresses recombination and DNA damage-induced deletions
10.1128/jb.00275-06 · 2006 · External reference
Prokaryotic nucleotide excision repair
10.1101/cshperspect.a012591 · 2013 · External reference
DNA helicase Srs2 disrupts the Rad51 presynaptic filament
10.1038/nature01577 · 2003 · External reference
Uvrd controls the access of recombination proteins to blocked replication forks
10.1038/sj.emboj.7601804 · 2007 · External reference
Rep and PriA helicase activities prevent RecA from provoking unnecessary recombination during replication fork repair
10.1101/gad.382306 · 2006 · External reference
The UvrD helicase and its modulation by the mismatch repair protein MutL
10.1093/nar/gkl450 · 2006 · External reference
Survival of recombination-deficient mutants of Escherichia coli during incubation with nalidixic acid
10.1128/jb.134.3.1195-1198.1978 · 1978 · External reference
Replication–transcription conflicts in bacteria
10.1038/nrmicro2800 · 2012 · External reference
Co-directional replication–transcription conflicts lead to replication restart
10.1038/nature09758 · 2011 · External reference
Recombination proteins and rescue of arrested replication forks
10.1016/j.dnarep.2007.02.016 · 2007 · External reference
Recq helicase and RecJ nuclease provide complementary functions to resect DNA for homologous recombination
10.1073/pnas.1420009111 · 2014 · External reference
Dominant mutations (lex) in Escherichia coli K-12 which affect radiation sensitivity and frequency of ultraviolet light-induced mutations
10.1128/jb.112.2.886-893.1972 · 1972 · External reference
Isolation of SOS constitutive mutants of Escherichia coli
10.1128/jb.186.21.7149-7160.2004 · 2004 · External reference
Mutations in uvrD induce the SOS response in Escherichia coli
10.1128/jb.171.1.303-307.1989 · 1989 · External reference
Mechanistic insights into transcription coupled DNA repair
10.1016/j.dnarep.2017.06.006 · 2017 · External reference
Active displacement of RecA filaments by UvrD translocase activity
10.1093/nar/gkv186 · 2015 · External reference
Order and disorder in bacterial genomes
10.1016/j.mib.2004.08.006 · 2004 · External reference
Suppression of spontaneous genome rearrangements in yeast DNA helicase mutants
10.1073/pnas.0608566103 · 2006 · External reference
Characterization of number, DNA content, viability and cell size of bacteria from natural environments using DAPI/PI dual staining and flow cytometry
1996 · External reference
Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability
10.1042/bj20060450 · 2006 · External reference
The SOS regulatory network
10.1128/ecosalplus.5.4.3 · 2008 · External reference
Single-molecule live cell imaging of Rep reveals the dynamic interplay between an accessory replicative helicase and the replisome
10.1093/nar/gkz298 · 2019 · External reference
The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments
10.1038/nature01585 · 2003 · External reference
Uvrd helicase, unlike Rep helicase, dismantles RecA nucleoprotein filaments in Escherichia coli
10.1038/sj.emboj.7600485 · 2005 · External reference
Lethality of bypass polymerases in Escherichia coli cells with a defective clamp loader complex of DNA polymerase III
10.1046/j.1365-2958.2003.03658.x · 2003 · External reference
The DinG protein from Escherichia coli is a structure-specific helicase
10.1074/jbc.m700376200 · 2007 · External reference
Characterization of the DNA damage-inducible helicase DinG from Escherichia coli
10.1074/jbc.m301188200 · 2003 · External reference
Tetrameric UvrD helicase is located at the E. coli replisome due to frequent replication blocks
10.1016/j.jmb.2023.168369 · 2024 · External reference
Control of ribosome synthesis in bacteria: the important role of rRNA chain elongation rate
10.1007/s11427-020-1742-4 · 2021 · External reference
Recombinant levels of Escherichia coli K-12 mutants deficient in various replication, recombination, or repair genes
10.1128/jb.134.3.958-966.1978 · 1978 · External reference
