Research graph
References from Ribosome-associated chaperones integrate co-translational mitochondrial protein import, stress signaling, and proteostasis in Saccharomyces cerevisiae. Local targets link to admitted publications; unresolved targets remain external evidence.
Interplays of AMPK and TOR in autophagy regulation in yeast
10.3390/cells12040519 · 2023 · External reference
Specific binding of tetratricopeptide repeat proteins to heat shock protein 70 (Hsp70) and heat shock protein 90 (Hsp90) is regulated by affinity and phosphorylation
10.1021/acs.biochem.5b00801 · 2015 · External reference
Positively charged amino acids at the N terminus of select mitochondrial proteins mediate early recognition by import proteins αβ'-NAC and Sam37
10.1016/j.jbc.2022.101984 · 2022 · External reference
From cytosol to mitochondria: the beginning of a protein journey
10.1515/hsz-2020-0110 · 2020 · External reference
Cell organelles and yeast longevity: an intertwined regulation
10.1007/s00294-019-01035-0 · 2020 · External reference
Msp1 cooperates with the proteasome for extraction of arrested mitochondrial import intermediates
10.1091/mbc.e19-06-0329 · 2020 · External reference
Synthesis and sorting of mitochondrial translation products
10.1007/978-1-59745-261-8_7 · 2008 · External reference
Mechanisms by which different functional states of mitochondria define yeast longevity
10.3390/ijms16035528 · 2015 · External reference
The structure of the eukaryotic ribosome at 3.0 Å resolution
10.1126/science.1212642 · 2011 · External reference
The ribosome-associated chaperone Zuo1 controls translation upon TORC1 inhibition
10.15252/embj.2022113240 · 2023 · External reference
Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme
10.1038/s41556-019-0294-5 · 2019 · External reference
How the mitoprotein-induced stress response safeguards the cytosol: a unified view
10.1016/j.tcb.2019.12.003 · 2020 · External reference
Homeostatic adjustment and metabolic remodeling in glucose-limited yeast cultures
10.1091/mbc.e04-11-0968 · 2005 · External reference
Tracing the evolutionary pathway: on the origin of mitochondria and eukaryogenesis
10.1111/febs.70109 · 2025 · External reference
Nutritional control of growth and development in yeast
10.1534/genetics.111.135731 · 2012 · External reference
Mitochondrial signaling: the retrograde response
10.1016/s1097-2765(04)00179-0 · 2004 · External reference
Importing mitochondrial proteins: machineries and mechanisms
10.1016/j.cell.2009.08.005 · 2009 · External reference
Cytoplasmic ribosomes on mitochondria alter the local membrane environment for protein import
10.1083/jcb.202407110 · 2025 · External reference
The principles of protein targeting and transport across cell membranes
10.1007/s10930-019-09847-2 · 2019 · External reference
Yeast petites and small colony variants: for everything there is a season
10.1016/b978-0-12-407672-3.00001-0 · 2013 · External reference
Defining the specificity of cotranslationally acting chaperones by systematic analysis of MRNAs associated with ribosome-nascent chain complexes
10.1371/journal.pbio.1001100 · 2011 · External reference
Quality control of protein import into mitochondria
10.1042/bcj20190584 · 2021 · External reference
Chaperone interactions at the ribosome
10.1101/cshperspect.a033977 · 2019 · External reference
Profiling Ssb-nascent chain interactions reveals principles of Hsp70-assisted folding
10.1016/j.cell.2017.06.038 · 2017 · External reference
Nascent polypeptide-associated complex stimulates protein import into yeast mitochondria
10.1091/mbc.10.10.3289 · 1999 · External reference
Localization of MRNAs coding for mitochondrial proteins in the yeast Saccharomyces cerevisiae
10.1261/rna.2621111 · 2011 · External reference
The principle of antagonism ensures protein targeting specificity at the endoplasmic reticulum
10.1126/science.aaa5335 · 2015 · External reference
The yeast nascent polypeptide-associated complex initiates protein targeting to mitochondria in vivo
10.1073/pnas.95.5.2296 · 1998 · External reference
The nascent polypeptide-associated complex (NAC) promotes interaction of ribosomes with the mitochondrial surface in vivo
10.1016/s0014-5793(02)02528-0 · 2002 · External reference
Visualization of cytosolic ribosomes on the surface of mitochondria by electron cryo-tomography
10.15252/embr.201744261 · 2017 · External reference
Assays for the biochemical and ultrastructural measurement of selective and nonselective types of autophagy in the yeast Saccharomyces cerevisiae
10.1016/j.ymeth.2014.11.023 · 2015 · External reference
Affinity purification of ribosomes to access the translatome
10.1016/j.ymeth.2009.04.003 · 2009 · External reference
Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction
10.1038/ncomms13695 · 2016 · External reference
Transport of proteins into mitochondria
10.1007/s10930-019-09819-6 · 2019 · External reference
Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis
10.1371/journal.pgen.1000407 · 2009 · External reference
Retrograde signaling mediates an adaptive survival response to endoplasmic reticulum stress in Saccharomyces Cerevisiae
10.1242/jcs.241539 · 2020 · External reference
Management of the endoplasmic reticulum stress by activation of the heat shock response in yeast
10.1111/1567-1364.12125 · 2014 · External reference
Global analysis of protein localization in budding yeast
10.1038/nature02026 · 2003 · External reference
Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon
10.1038/ncomms10471 · 2016 · External reference
Cytoplasmic type 80S ribosomes associated with yeast mitochondria. IV. Attachment of ribosomes to the outer membrane of isolated mitochondria
10.1083/jcb.65.1.1 · 1975 · External reference
ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins
10.1016/j.celrep.2024.114473 · 2024 · External reference
Glycerol metabolism and transport in yeast and fungi: established knowledge and ambiguities
10.1111/1462-2920.13617 · 2017 · External reference
Import into mitochondria, folding and retrograde movement of fumarase in yeast
10.1074/jbc.273.40.25587 · 1998 · External reference
A dual function for chaperones SSB-RAC and the NAC nascent polypeptide-associated Complex on ribosomes
10.1083/jcb.200910074 · 2010 · External reference
The mitochondrial outer membrane protein Tom70-mediator in protein traffic, membrane contact sites and innate immunity
10.3390/ijms21197262 · 2020 · External reference
A central role for the peroxisomal membrane in glyoxylate cycle function
10.1016/j.bbamcr.2006.09.009 · 2006 · External reference
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
10.1038/227680a0 · 1970 · External reference
Adaptation to different types of stress converge on mitochondrial metabolism
10.1091/mbc.e16-03-0187 · 2016 · External reference
Rim15-dependent activation of Hsf1 and Msn2/4 transcription factors by direct phosphorylation in Saccharomyces cerevisiae
10.1016/j.febslet.2013.10.004 · 2013 · External reference
OM14 is a mitochondrial receptor for cytosolic ribosomes that supports co-translational import into mitochondria
10.1038/ncomms6711 · 2014 · External reference
Intramitochondrial functions regulate nonmitochondrial citrate synthase (CIT2) expression in Saccharomyces cerevisiae
10.1128/mcb.11.1.38 · 1991 · External reference
A transcriptional switch in the expression of yeast tricarboxylic acid cycle genes in response to a reduction or loss of respiratory function
10.1128/mcb.19.10.6720 · 1999 · External reference
Mitochondrial retrograde signaling
10.1146/annurev.genet.40.110405.090613 · 2006 · External reference
Manganese activation of superoxide dismutase 2 in the mitochondria of Saccharomyces cerevisiae
10.1074/jbc.m504257200 · 2005 · External reference
Buffer modulation of menadione-induced oxidative stress in Saccharomyces cerevisiae
10.1179/135100009x12525712409454 · 2009 · External reference
Cytoplasmic protein misfolding titrates Hsp70 to activate nuclear Hsf1
10.7554/elife.47791 · 2019 · External reference
Msp1 clears mistargeted proteins by facilitating their transfer from mitochondria to the ER
10.1016/j.molcel.2019.07.006 · 2019 · External reference
Optimized mechanical isolation of mitochondria from Saccharomyces cerevisiae preserving Atg32 for quantitative analysis
10.21769/bioprotoc.5610 · 2026 · External reference
Loss of mitochondrial membrane potential triggers the retrograde response extending yeast replicative lifespan
10.3389/fgene.2011.00102 · 2011 · External reference
Yeast chronological lifespan: longevity regulatory genes and mechanisms
10.3390/cells11101714 · 2022 · External reference
TORC1 controls G1-S cell cycle transition in yeast via Mpk1 and the greatwall kinase pathway
10.1038/ncomms9256 · 2015 · External reference
The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway
10.1038/s41467-017-00635-z · 2017 · External reference
Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast
10.1128/mcb.21.13.4347-4368.2001 · 2001 · External reference
SRP samples nascent chains for the presence of signal sequences by interacting with ribosomes at a discrete step during translation elongation
10.1016/s0092-8674(05)80012-1 · 1995 · External reference
Tetrazolium overlay technique for population studies of respiration deficiency in yeast
10.1126/science.125.3254.928 · 1957 · External reference
Functional dissection of the nascent polypeptide-associated complex in Saccharomyces cerevisiae
10.1371/journal.pone.0143457 · 2015 · External reference
Mitochondrial proteins: from biogenesis to functional networks
10.1038/s41580-018-0092-0 · 2019 · External reference
Αβ′-NAC cooperates with Sam37 to mediate early stages of mitochondrial protein import
10.1111/febs.14024 · 2017 · External reference
Evolution of mitochondrial oxa proteins from bacterial YidC. Inherited and acquired functions of a conserved protein insertion machinery
10.1074/jbc.m414093200 · 2005 · External reference
The ribosome-associated complex regulates cytosolic translation upon mitoprotein-induced stress
10.1111/febs.70356 · 2026 · External reference
Identification of fungal cell wall mutants using susceptibility assays based on calcofluor white and Congo red
10.1038/nprot.2006.397 · 2006 · External reference
NAC regulates metabolism and cell fate in intestinal stem cells
10.1126/sciadv.adn9750 · 2025 · External reference
The unfolded protein response: an overview
10.3390/biology10050384 · 2021 · External reference
Dual localization of fumarase is dependent on the integrity of the glyoxylate shunt
10.1111/j.1365-2958.2009.06659.x · 2009 · External reference
The origin and diversification of mitochondria
10.1016/j.cub.2017.09.015 · 2017 · External reference
The tetratricopeptide repeats of receptors involved in protein translocation across membranes
10.1093/molbev/msm211 · 2007 · External reference
Evolution of mitochondrial protein import—lessons from trypanosomes
10.1515/hsz-2019-0444 · 2020 · External reference
Transcriptional control of nonfermentative metabolism in the yeast Saccharomyces cerevisiae
10.1007/s00294-003-0381-8 · 2003 · External reference
Carbon catabolite repression in yeast is not limited to glucose
10.1038/s41598-019-43032-w · 2019 · External reference
Defining the essential function of yeast Hsf1 reveals a compact transcriptional program for maintaining eukaryotic proteostasis
10.1016/j.molcel.2016.05.014 · 2016 · External reference
The Delitto Perfetto approach to in vivo site-directed mutagenesis and chromosome rearrangements with synthetic oligonucleotides in yeast
10.1016/s0076-6879(05)09019-1 · 2006 · External reference
Two alternative binding mechanisms connect the protein translocation Sec71-Sec72 Complex with heat shock proteins
10.1074/jbc.m116.761122 · 2017 · External reference
Transcriptional regulation of nonfermentable carbon utilization in budding yeast
10.1111/j.1567-1364.2009.00555.x · 2010 · External reference
Biology of the heat shock response and protein chaperones: budding yeast (Saccharomyces cerevisiae) as a model system
10.1128/mmbr.05018-11 · 2012 · External reference
MitoCPR-A surveillance pathway that protects mitochondria in response to protein import stress
10.1126/science.aan4146 · 2018 · External reference
SRP meets the ribosome
10.1038/nsmb853 · 2004 · External reference
Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling
10.1126/science.1257522 · 2014 · External reference
Translation-coupled translocation of yeast fumarase into mitochondria in vivo
10.1074/jbc.m704201200 · 2007 · External reference
Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70
10.1016/s0092-8674(02)01250-3 · 2003 · External reference
The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb
10.1038/s41467-020-15313-w · 2020 · External reference
Yeast molecular chaperone gene SSB2 is involved in the endoplasmic reticulum stress response
10.1007/s10482-018-1189-3 · 2019 · External reference
