Research graph
References from Ataxin-2 regulates the synaptonemal complex to ensure chromosome pairing during female meiosis. Local targets link to admitted publications; unresolved targets remain external evidence.
Meiotic chromosome structure, the synaptonemal complex, and infertility
10.1146/annurev-genom-110122-090239 · 2023 · External reference
RNP-granule assembly via ataxin-2 disordered domains is required for long-term memory and neurodegeneration
10.1016/j.neuron.2018.04.032 · 2018 · External reference
SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56
10.1083/jcb.202009167 · 2021 · External reference
The Drosophila CPEB protein orb specifies oocyte fate by a 3′UTR-dependent autoregulatory loop
10.1534/genetics.119.302687 · 2019 · External reference
GCNA preserves genome integrity and fertility across species
10.1016/j.devcel.2019.11.007 · 2020 · External reference
The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin interactions
10.1038/35087045 · 2001 · External reference
A discrete transcriptional silencer in the bam gene determines asymmetric division of the Drosophila germline stem cell
10.1242/dev.00325 · 2003 · External reference
Synaptonemal complex components promote centromere pairing in pre-meiotic germ cells
10.1371/journal.pgen.1004012 · 2013 · External reference
ATX-2, the C. elegans ortholog of ataxin 2, functions in translational regulation in the germline
10.1242/dev.01352 · 2004 · External reference
Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila
10.1016/s1097-2765(00)80368-8 · 1999 · External reference
Rapid and accurate identification of ribosomal RNA sequences via deep learning
10.1093/nar/gkac112 · 2022 · External reference
Polycomb group (PcG) proteins prevent the assembly of abnormal synaptonemal complex structures during meiosis
10.1073/pnas.2204701119 · 2022 · External reference
Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis
10.1016/j.devcel.2010.02.013 · 2010 · External reference
Multiple synaptonemal complexes (polycomplexes): origin, structure and function
10.1016/0309-1651(87)90157-3 · 1987 · External reference
FlyBase: a guided tour of highlighted features
10.1093/genetics/iyac035 · 2022 · External reference
Precipitation of RNA with ethanol
10.1101/pdb.prot101717 · 2020 · External reference
Alternative synaptonemal complex structures: too much of a good thing?
10.1016/j.tig.2020.07.007 · 2020 · External reference
Female meiosis: synapsis, recombination, and segregation in Drosophila melanogaster
10.1534/genetics.117.300081 · 2018 · External reference
Direct evidence that Ataxin-2 is a translational activator mediating cytoplasmic polyadenylation
10.1074/jbc.ra120.013835 · 2020 · External reference
Germline progenitors escape the widespread phenomenon of homolog pairing during Drosophila development
10.1371/journal.pgen.1004013 · 2013 · External reference
IME1, a positive regulator gene of meiosis in S. cerevisiae
10.1016/0092-8674(88)90427-8 · 1988 · External reference
Gprofiler2—an R package for gene list functional enrichment analysis and namespace conversion toolset g:Profiler
10.12688/f1000research.24956.2 · 2020 · External reference
SortMeRNA: fast and accurate filtering of ribosomal RNAs in metatranscriptomic data
10.1093/bioinformatics/bts611 · 2012 · External reference
LSM12 and ME31B/DDX6 define distinct modes of posttranscriptional regulation by ATAXIN-2 protein complex in Drosophila circadian pacemaker neurons
10.1016/j.molcel.2017.03.004 · 2017 · External reference
Synaptonemal complex in human biology and disease
10.3390/cells12131718 · 2023 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
Transgenerational dynamics of rDNA copy number in Drosophila male germline stem cells
10.7554/elife.32421 · 2018 · External reference
Caenorhabditis elegans atx-2 promotes germline proliferation and the oocyte fate
10.1534/genetics.104.029355 · 2004 · External reference
Pbp1p, a factor interacting with Saccharomyces cerevisiae poly(A)-binding protein, regulates polyadenylation
10.1128/mcb.18.12.7383 · 1998 · External reference
The Synaptonemal complex component C(2)M regulates meiotic crossing over in Drosophila
10.1016/s0960-9822(03)00050-2 · 2003 · External reference
Oo-site: a dashboard to visualize gene expression during Drosophila oogenesis suggests meiotic entry is regulated post-transcriptionally
10.1242/bio.059286 · 2022 · External reference
Msl3 promotes germline stem cell differentiation in female Drosophila
10.1242/dev.199625 · 2022 · External reference
Cytological analysis of meiosis in fixed Drosophila ovaries
10.1007/978-1-60761-103-5_12 · 2009 · External reference
10.1101/2025.06.13.659559
10.1101/2025.06.13.659559 · External reference
Ataxin-2, Twenty-four, and Dicer-2 are components of a noncanonical cytoplasmic polyadenylation complex
10.26508/lsa.202201417 · 2022 · External reference
FlyBase: updates to the Drosophila genes and genomes database
10.1093/genetics/iyad211 · 2024 · External reference
Mitochondrial DNA quality control in the female germline requires a unique programmed mitophagy
10.1016/j.cmet.2022.10.005 · 2022 · External reference
Salmon provides fast and bias-aware quantification of transcript expression
10.1038/nmeth.4197 · 2017 · External reference
Structured and disordered regions of Ataxin-2 contribute differently to the specificity and efficiency of mRNP granule formation
10.1371/journal.pgen.1011251 · 2024 · External reference
Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila
10.1073/pnas.1405500111 · 2014 · External reference
The SILVA ribosomal RNA gene database project: improved data processing and web-based tools
10.1093/nar/gks1219 · 2013 · External reference
Fbxo42 promotes the degradation of Ataxin-2 granules to trigger terminal Xbp1 signaling
10.1038/s41467-025-62417-2 · 2025 · External reference
A Drosophila homolog of the polyglutamine disease gene SCA2 is a dosage-sensitive regulator of actin filament formation
10.1093/genetics/162.4.1687 · 2002 · External reference
Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes
10.1093/hmg/ddl173 · 2006 · External reference
Fiji: an open-source platform for biological-image analysis
10.1038/nmeth.2019 · 2012 · External reference
NIH Image to ImageJ: 25 years of image analysis
10.1038/nmeth.2089 · 2012 · External reference
Antagonistic roles for Ataxin-2 structured and disordered domains in RNP condensation
10.7554/elife.60326 · 2021 · External reference
A single-cell atlas reveals unanticipated cell type complexity in Drosophila ovaries
10.1101/gr.274340.120 · 2021 · External reference
Translational control in germline stem cell development
10.1083/jcb.201407102 · 2014 · External reference
Smaug, a novel and conserved protein, contributes to repression of nanos mRNA translation in vitro
10.1017/s1355838299991392 · 1999 · External reference
Smaug protein represses translation of unlocalized nanos mRNA in the Drosophila embryo
10.1101/gad.10.20.2600 · 1996 · External reference
Amplification of genes for chorion proteins during oogenesis in Drosophila melanogaster
10.1073/pnas.77.2.1096 · 1980 · External reference
Synaptonemal complex-dependent centromeric clustering and the initiation of synapsis in Drosophila oocytes
10.1016/j.cub.2011.09.044 · 2011 · External reference
A pathway for synapsis initiation during zygotene in Drosophila oocytes
10.1016/j.cub.2011.10.005 · 2011 · External reference
Transcriptomic analysis of meiotic genes during the mitosis-to-meiosis transition in Drosophila females
10.1093/genetics/iyae130 · 2024 · External reference
Unresolved reference
2020 · External reference
Unresolved reference
2016 · External reference
From conservation to adaptation: understanding the synaptonemal complex's evolutionary dynamics
10.1016/j.gde.2025.102349 · 2025 · External reference
Direct binding of Ataxin-2 to distinct elements in 3′ UTRs promotes mRNA stability and protein expression
10.1016/j.molcel.2014.05.022 · 2014 · External reference
The LSmAD domain of ataxin-2 modulates the structure and RNA binding of its preceding LSm domain
10.3390/cells14050383 · 2025 · External reference
Meiosis: dances between homologs
10.1146/annurev-genet-061323-044915 · 2023 · External reference
