Research graph
References from Impact of naturally occurring target-site polymorphisms on an autonomous Cas9/guide RNA-based gene drive system for population modification of Anopheles gambiae s.l.. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2023 · External reference
Experimental determination of the force of malaria infection reveals a nonlinear relationship to mosquito sporozoite loads
10.1371/journal.ppat.1008181 · 2020 · External reference
Considerations for homology-based DNA repair in mosquitoes: impact of sequence heterology and donor template source
10.1371/journal.pgen.1010060 · 2022 · External reference
Genetic diversity of the African malaria vector Anopheles gambiae
10.1038/nature24995 · 2017 · External reference
Sequencing of Culex quinquefasciatus establishes a platform for mosquito comparative genomics
10.1126/science.1191864 · 2010 · External reference
Differential effects of inbreeding and selection on male reproductive phenotype associated with the colonization and laboratory maintenance of Anopheles gambiae
10.1186/1475-2875-13-19 · 2014 · External reference
Unresolved reference
2024 · External reference
Transmission-blocking interventions eliminate malaria from laboratory populations
10.1038/ncomms2840 · 2013 · External reference
Next-generation gene drive for population modification of the malaria vector mosquito, Anopheles gambiae
10.1073/pnas.2010214117 · 2020 · External reference
Cas9-mediated maternal-effect and derived resistance alleles in a gene-drive strain of the African malaria vector mosquito, Anopheles gambiae
10.1093/genetics/iyac055 · 2022 · External reference
Dual effector population modification gene-drive strains of the African malaria mosquitoes, Anopheles gambiae and Anopheles coluzzii
10.1073/pnas.2221118120 · 2023 · External reference
Mutant allele formation and inheritance during Cas9/guide RNA-mediated gene drive in a population modification mosquito strain for human malaria control
10.1093/genetics/iyaf176 · 2025 · External reference
Compound effector genes suppress malaria parasite infections in gene-drive population modification strains of the African malaria mosquitoes, Anopheles gambiae and Anopheles coluzzii
10.1093/g3journal/jkag014 · 2026 · External reference
Long-term stability and performance of Cas9/guide RNA-based gene drives in anopheline mosquitoes
10.1073/pnas.2605739123 · 2026 · External reference
Population modification of anopheline species to control malaria transmission
10.1080/20477724.2018.1427192 · 2017 · External reference
Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed gRNAs
10.1126/sciadv.aaz0525 · 2020 · External reference
Predicting mosquito infection from Plasmodium falciparum gametocyte density and estimating the reservoir of infection
10.7554/elife.00626 · 2013 · External reference
CRISPResso2 provides accurate and rapid genome editing sequence analysis
10.1038/s41587-019-0032-3 · 2019 · External reference
CRISPR/cas9 gene drives in genetically variable and nonrandomly mating wild populations
10.1126/sciadv.1601910 · 2017 · External reference
Heterosis increases fertility, fecundity, and survival of laboratory-produced F1 hybrid males of the malaria mosquito Anopheles coluzzii
10.1534/g3.115.021436 · 2015 · External reference
Systematic decomposition of sequence determinants governing CRISPR/cas9 specificity
10.1038/s41467-022-28028-x · 2022 · External reference
Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi
10.1073/pnas.1521077112 · 2015 · External reference
Examining the human infectious reservoir for Plasmodium falciparum malaria in areas of differing transmission intensity
10.1038/s41467-017-01270-4 · 2017 · External reference
When is a plasmodium-infected mosquito an infectious mosquito?
10.1016/j.pt.2020.05.011 · 2020 · External reference
Sequence mismatch between gene-drive and target-site flanking regions significantly impairs homing efficiency in Culex quinquefasciatus
10.1093/genetics/iyag013 · 2026 · External reference
DNA targeting specificity of RNA-guided Cas9 nucleases
10.1038/nbt.2647 · 2013 · External reference
Engineered resistance to Plasmodium falciparum development in transgenic Anopheles stephensi
10.1371/journal.ppat.1002017 · 2011 · External reference
Transgenic Anopheles stephensi coexpressing single-chain antibodies resist Plasmodium falciparum development
10.1073/pnas.1207738109 · 2012 · External reference
High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells
10.1038/s41551-019-0505-1 · 2020 · External reference
A CRISPR–cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes
10.1038/nbt.4245 · 2018 · External reference
A thousand fly genomes: an expanded Drosophila genome nexus
10.1093/molbev/msw195 · 2016 · External reference
Improved reference genome of Aedes aegypti informs arbovirus vector control
10.1038/s41586-018-0692-z · 2018 · External reference
Engineering resilient gene drives for sustainable malaria control by predicting, testing and overcoming target site resistance in Anopheles gambiae
10.1371/journal.pbio.3003879 · 2026 · External reference
Unresolved reference
External reference
Measuring the impact of genetic heterogeneity and chromosomal inversions on the efficacy of CRISPR-cas9 gene drives in different strains of Anopheles gambiae
10.1089/crispr.2023.0030 · 2023 · External reference
Directional R-loop formation by the CRISPR-cas surveillance complex cascade provides efficient off-target site rejection
10.1016/j.celrep.2015.02.013 · 2015 · External reference
MGDrivE: a modular simulation framework for the spread of gene drives through spatially explicit mosquito populations
10.1111/2041-210x.13318 · 2020 · External reference
Abundance of conserved CRISPR-cas9 target sites within the highly polymorphic genomes of anopheles and Aedes mosquitoes
10.1038/s41467-020-15204-0 · 2020 · External reference
Plasmodium falciparum gametocyte culture and mosquito infection through artificial membrane feeding
10.3791/61426 · 2020 · External reference
Cas9/guide RNA-based gene-drive dynamics following introduction and introgression into diverse anopheline mosquito genetic backgrounds
10.1186/s12864-024-10952-7 · 2024 · External reference
Tools for Anopheles gambiae transgenesis
10.1534/g3.115.016808 · 2015 · External reference
Unresolved reference
2021 · External reference
10.30875/9789287074560
10.30875/9789287074560 · 2025 · External reference
Target specificity of the CRISPR-Cas9 system
10.1007/s40484-014-0030-x · 2014 · External reference
