Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Beyond clonality: invertons as engines of phenotypic heterogeneity in bacteria. Local targets link to admitted publications; unresolved targets remain external evidence.
An invertible element of DNA controls phase variation of type 1 fimbriae of Escherichia coli
10.1073/pnas.82.17.5724 · 1985 · External reference
Akkermansia muciniphila induces intestinal adaptive immune responses during homeostasis
10.1126/science.aaw7479 · 2019 · External reference
Systematic analysis of REBASE identifies numerous type I restriction-modification systems with duplicated, distinct hsdS specificity genes that can switch system specificity by recombination
10.1128/msystems.00497-20 · 2020 · External reference
100+ years of phase variation: the premier bacterial bet-hedging phenomenon
10.1099/mic.0.001537 · 2025 · External reference
Inflammation and bacteriophages affect DNA inversion states and functionality of the gut microbiota
10.1016/j.chom.2024.02.003 · 2024 · External reference
Bacteriophage-driven DNA inversions shape bacterial functionality and long-term co-existence in Bacteroides fragilis
10.1080/19490976.2025.2501492 · 2025 · External reference
Bistability and biofilm formation in Bacillus subtilis
10.1111/j.1365-2958.2007.06040.x · 2008 · External reference
Intragenic DNA inversions expand bacterial coding capacity
10.1038/s41586-024-07970-4 · 2024 · External reference
Expression of a uniquely regulated extracellular polysaccharide confers a large-capsule phenotype to Bacteroides fragilis
10.1128/jb.01519-07 · 2008 · External reference
A critical perspective on the supplementation of Akkermansia muciniphila: benefits and harms
10.3390/life13061247 · 2023 · External reference
DNA relaxation-dependent phase biasing of the fim genetic switch in Escherichia coli depends on the interplay of H-NS, IHF and LRP
10.1111/j.1365-2958.2009.06919.x · 2009 · External reference
Mpi recombinase globally modulates the surface architecture of a human commensal bacterium
10.1073/pnas.1832655100 · 2003 · External reference
A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility
10.1016/j.cell.2016.10.043 · 2016 · External reference
Phase-variable methylation and epigenetic regulation by type I restriction-modification systems
10.1093/femsre/fux025 · 2017 · External reference
Bistability in bacteria
10.1111/j.1365-2958.2006.05249.x · 2006 · External reference
Stochastic gene expression in a single cell
10.1126/science.1070919 · 2002 · External reference
The long-term stability of the human gut microbiota
10.1126/science.1237439 · 2013 · External reference
Salmonella typhimurium and inflammation: a pathogen-centric affair
10.1038/s41579-021-00561-4 · 2021 · External reference
Systematic identification and quantification of phase variation in commensal and pathogenic Escherichia coli
10.1186/s13073-014-0112-4 · 2014 · External reference
A phase-variable capsule facilitates Akkermansia muciniphila colonization of the intestinal mucus layer
10.1128/mbio.01048-26 · 2026 · External reference
Mechanisms of site-specific recombination
10.1146/annurev.biochem.73.011303.073908 · 2006 · External reference
Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse
10.1038/37925 · 1997 · External reference
Dynamics of phage-host interactions in Bacteroides fragilis resolved by single-cell transcriptomics
10.1038/s41467-026-70381-8 · 2026 · External reference
Asymmetry of shufflon-specific recombination sites in plasmid R64 inhibits recombination between direct sfx sequences
10.1074/jbc.m513654200 · 2006 · External reference
Extensive genomic variation within clonal complexes of Neisseria meningitidis
10.1093/gbe/evr119 · 2011 · External reference
Mechanisms of change in gene copy number
10.1038/nrg2593 · 2009 · External reference
The invertible G segment of phage mu
10.1016/0092-8674(80)90423-7 · 1980 · External reference
Prevalence of phase variable epigenetic invertons among host-associated bacteria
10.1093/nar/gkaa907 · 2020 · External reference
Invertible promoters mediate bacterial phase variation, antibiotic resistance, and host adaptation in the gut
10.1126/science.aau5238 · 2019 · External reference
Comprehensive profiling of genomic invertons in defined gut microbial community reveals associations with intestinal colonization and surface adhesion
10.1186/s40168-025-02052-7 · 2025 · External reference
Site-specific DNA inversion by serine recombinases
10.1128/microbiolspec.mdna3-0047-2014 · 2015 · External reference
Shufflons: multiple inversion systems and integrons
10.1146/annurev.genet.33.1.171 · 1999 · External reference
Extensive surface diversity of a commensal microorganism by multiple DNA inversions
10.1038/35107092 · 2001 · External reference
Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation
10.1073/pnas.0404172101 · 2004 · External reference
Single-cell analysis of multiple invertible promoters reveals differential inversion rates as a strong determinant of bacterial population heterogeneity
10.1126/sciadv.adg5476 · 2023 · External reference
Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing
10.1073/pnas.1210309109 · 2012 · External reference
The population and evolutionary dynamics of homologous gene recombination in bacterial populations
10.1371/journal.pgen.1000601 · 2009 · External reference
Slipped-strand mispairing: a major mechanism for DNA sequence evolution
10.1093/oxfordjournals.molbev.a040442 · 1987 · External reference
An IS-mediated, RecA-dependent, bet-hedging strategy in Burkholderia thailandensis
10.7554/elife.84327 · 2023 · External reference
An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
10.1016/j.cell.2005.05.007 · 2005 · External reference
Multiple interfaces between a serine recombinase and an enhancer control site-specific DNA inversion
10.7554/elife.01211 · 2013 · External reference
Diversity-generating retroelements
10.1016/j.mib.2007.06.004 · 2007 · External reference
Cre recombinase and other tyrosine recombinases
10.1021/acs.chemrev.6b00077 · 2016 · External reference
Systematic identification of gene-altering programmed inversions across the bacterial domain
10.1093/nar/gkac1166 · 2023 · External reference
Bacterial contingency loci: the role of simple sequence DNA repeats in bacterial adaptation
10.1146/annurev.genet.40.110405.090442 · 2006 · External reference
Identification of the site-specific DNA invertase responsible for the phase variation of SusC/SusD family outer membrane proteins in Bacteroides fragilis
10.1128/jb.00687-09 · 2009 · External reference
Epigenetic phase variation in the gut microbiome enhances bacterial adaptation
10.1016/j.chom.2026.04.019 · 2026 · External reference
Akkermansia muciniphila exacerbates food allergy in fibre-deprived mice
10.1038/s41564-023-01464-1 · 2023 · External reference
A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice
10.1038/nm.4236 · 2017 · External reference
Phase-variable capsular polysaccharides and lipoproteins modify bacteriophage susceptibility in Bacteroides thetaiotaomicron
10.1038/s41564-020-0746-5 · 2020 · External reference
A subset of polysaccharide capsules in the human symbiont Bacteroides thetaiotaomicron promote increased competitive fitness in the mouse gut
10.1016/j.chom.2017.08.020 · 2017 · External reference
Bacteroides fragilis synthesizes a DNA invertase affecting both a local and a distant region
10.1128/jb.01362-06 · 2007 · External reference
Salmonella versus the microbiome
10.1128/mmbr.00027-19 · 2021 · External reference
The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
10.1126/science.1206095 · 2011 · External reference
The bacterial epigenome
10.1038/s41579-019-0286-2 · 2020 · External reference
Genome-wide detection of conservative site-specific recombination in bacteria
10.1371/journal.pgen.1007332 · 2018 · External reference
Bacteroides and related species: the keystone taxa of the human gut microbiota
10.1016/j.anaerobe.2024.102819 · 2024 · External reference
The serine recombinases
10.1128/microbiolspec.mdna3-0046-2014 · 2014 · External reference
Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota
10.1371/journal.pbio.0050244 · 2007 · External reference
Evolution of the DNA invertase Gin of phage Mu and related site-specific recombination proteins
10.1002/j.1460-2075.1988.tb02935.x · 1989 · External reference
A phase-variable surface layer from the gut symbiont Bacteroides thetaiotaomicron
10.1128/mbio.01339-15 · 2015 · External reference
Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats
10.1002/bit.24994 · 2014 · External reference
Orientations of the Bacteroides fragilis capsular polysaccharide biosynthesis locus promoters during symbiosis and infection
10.1128/jb.00555-10 · 2010 · External reference
Site-specific recombination—how simple DNA inversions produce complex phenotypic heterogeneity in bacterial populations
10.1016/j.tig.2020.09.004 · 2021 · External reference
Phase and antigenic variation in bacteria
10.1128/cmr.17.3.581-611.2004 · 2004 · External reference
An insider's perspective: bacteroides as a window into the microbiome
10.1038/nmicrobiol.2017.26 · 2017 · External reference
A microbial modified prisoner's dilemma game: how frequency-dependent selection can lead to random phase variation
10.1016/j.jtbi.2004.11.021 · 2005 · External reference
Diversity in times of adversity: probabilistic strategies in microbial survival games
10.1016/j.jtbi.2004.11.020 · 2005 · External reference
Bacteroidales species in the human gut are a reservoir of antibiotic resistance genes regulated by invertible promoters
10.1038/s41522-021-00260-1 · 2022 · External reference
10.64898/2026.04.24.720693
10.64898/2026.04.24.720693 · 2026 · External reference
Analysis of the nucleotide sequence of an invertible controlling element
10.1073/pnas.77.7.4196 · 1980 · External reference