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References from Alterations in Oxygen Consumption, Respiratory Quotient, and Heat Production in Long-Lived GHRKO and Ames Dwarf Mice, and Short-Lived bGH Transgenic Mice. Local targets link to admitted publications; unresolved targets remain external evidence.
Minireview: role of the growth hormone/insulin-like growth factor system in mammalian aging
10.1210/en.2005-0411 · 2005 · External reference
La production de chaleur de la souris. Etude de plusieurs races de souris
1936 · External reference
Reduced levels of thyroid hormones, insulin, and glucose, and lower body core temperature in the growth hormone receptor/binding protein knockout mouse
10.1177/153537020122600607 · 2001 · External reference
Oxidative stress, redox imbalance, and the aging process
10.1089/152308603770310149 · 2003 · External reference
Free radical theory of aging
10.1016/0921-8734(92)90030-s · 1992 · External reference
Effect of growth hormone on susceptibility to diet-induced obesity
10.1210/en.2006-0086 · 2006 · External reference
How does calorie restriction work?
10.1101/gad.1052903 · 2003 · External reference
The retardation of aging by caloric restriction: studies in rodents and primates
10.1177/019262339602400618 · 1996 · External reference
Neuroendocrine and pharmacological manipulations to assess how caloric restriction increases life span
10.1093/gerona/56.suppl_1.34 · 2001 · External reference
Calorie restriction in mice: effects on body composition, daily activity, metabolic rate, mitochondrial reactive oxygen species production, and membrane fatty acid composition
10.1093/gerona/61.8.781 · 2006 · External reference
Modulation of free radicals and superoxide dismutases by age and dietary restriction
1990 · External reference
Does food restriction retard aging by reducing the metabolic rate?
1985 · External reference
Mid-life temperature-transfer effects on life-span of annual fish
10.1093/geronj/30.2.129 · 1975 · External reference
Unresolved reference
1928 · External reference
A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)
10.1073/pnas.94.24.13215 · 1997 · External reference
Tissue-specific expression and dietary regulation of a chimeric phosphoenolpyruvate carboxykinase/bovine growth hormone gene in transgenic mice
10.1016/s0021-9258(18)37977-8 · 1988 · External reference
Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ
1990 · External reference
Fasting respiratory exchange ratio and resting metabolic rate as predictors of weight gain: the Baltimore Longitudinal Study on Aging
1992 · External reference
Respiratory quotient is inversely associated with muscle sympathetic nerve activity
10.1210/jcem.83.11.5265 · 1998 · External reference
Family history of diabetes links impaired substrate switching and reduced mitochondrial content in skeletal muscle
10.2337/db06-0521 · 2007 · External reference
Thermogenic mechanisms and their hormonal regulation
10.1152/physrev.00009.2005 · 2006 · External reference
Expression of human, but not bovine growth hormone genes promotes development of mammary tumors in transgenic mice
1994 · External reference
Unresolved reference
1883 · External reference
Body size and metabolism
10.3733/hilg.v06n11p315 · 1932 · External reference
Long-lived growth hormone receptor knockout mice show a delay in age-related changes of body composition and bone characteristics
10.1093/gerona/61.6.562 · 2006 · External reference
Comparing adiposity profiles in three mouse models with altered GH signaling
10.1016/j.ghir.2004.02.005 · 2004 · External reference
Cellular energy utilization and molecular origin of standard metabolic rate in mammals
10.1152/physrev.1997.77.3.731 · 1997 · External reference
Body composition of prolactin-, growth hormone-, and thyrotropin-deficient Ames dwarf mice
10.1385/endo:20:1-2:149 · 2003 · External reference
Genetic models in the study of anterior pituitary hormones
1979 · External reference
Effects of growth hormone overexpression and growth hormone resistance on neuroendocrine and reproductive functions in transgenic and knock-out mice
10.1046/j.1525-1373.1999.d01-121.x · 1999 · External reference
Growth hormone and metabolism
10.1016/b978-0-12-629055-4.50008-8 · 1993 · External reference
Long-term growth hormone excess induces marked alterations in lipoprotein metabolism in mice
10.1152/ajpendo.2001.281.6.e1230 · 2001 · External reference
Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor 1/insulin signaling and caloric restriction
10.1210/en.2004-1120 · 2005 · External reference
Adipocytokines and lipid levels in Ames dwarf and caloric restricted mice
10.1093/gerona/61.4.323 · 2006 · External reference
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
10.1038/nm788 · 2002 · External reference
Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice
10.1210/en.2006-1313 · 2007 · External reference
Low body temperature in long-lived Ames dwarf mice at rest and during stress
10.1016/s0031-9384(99)00098-0 · 1999 · External reference
Effect of long-term caloric restriction on oxygen consumption and body temperature in two different strains of mice
10.1016/j.mad.2007.07.005 · 2007 · External reference
Enlargement of interscapular brown adipose tissue in growth hormone antagonist transgenic and in growth hormone receptor gene-disrupted dwarf mice
10.1177/153537020322800212 · 2003 · External reference
3,5,3′-Triiodothyronine actively stimulates UCP in brown fat under minimal sympathetic activity
1999 · External reference
T(3) stimulates resting metabolism and UCP-2 and UCP-3 mRNA but not nonphosphorylating mitochondrial respiration in mice
1999 · External reference
Aging: a theory based on free radical and radiation chemistry
10.1093/geronj/11.3.298 · 1956 · External reference
Respiratory chain linked H(2)O(2) production in pigeon heart mitochondria
10.1016/0014-5793(71)80459-3 · 1971 · External reference
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
10.1038/nature00829 · 2002 · External reference
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
10.1073/pnas.0510452103 · 2006 · External reference
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
10.1126/science.1117728 · 2005 · External reference
Uncoupling to survive? The role of mitochondrial inefficiency in ageing
10.1016/s0531-5565(00)00135-2 · 2000 · External reference
Mitochondrial oxidant generation and oxidative damage in Ames dwarf and GH transgenic mice
2001 · External reference
Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice
10.1055/s-2002-34787 · 2002 · External reference
Fat metabolism links germline stem cells and longevity in C. elegans
10.1126/science.1162011 · 2008 · External reference