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References from A Western-style diet exacerbates male infertility in M1ap knockout mice. Local targets link to admitted publications; unresolved targets remain external evidence.
Meiosis I arrest abnormalities lead to severe oligozoospermia in meiosis 1 arresting protein (M1ap)-deficient mice
10.1095/biolreprod.111.098673 · 2013 · External reference
Intergenerational effects of a paternal Western diet during adolescence on offspring gut microbiota, stress reactivity, and social behavior
10.1096/fj.202100920rr · 2022 · External reference
Irreversible male infertility from sleep restriction: a dual hit on testicular steroidogenesis and Keap1-Nrf2-mediated antioxidant defense
10.1016/j.reprotox.2025.109083 · 2025 · External reference
A meiotic XPF-ERCC1-like complex recognizes joint molecule recombination intermediates to promote crossover formation
10.1101/gad.308510.117 · 2018 · External reference
The human testis-specific proteome defined by transcriptomics and antibody-based profiling
10.1093/molehr/gau018 · 2014 · External reference
The katanin A-subunits KATNA1 and KATNAL1 act co-operatively in mammalian meiosis and spermiogenesis to achieve male fertility
10.1242/dev.201956 · 2023 · External reference
KATNB1 is a master regulator of multiple katanin enzymes in male meiosis and haploid germ cell development
10.1242/dev.199922 · 2021 · External reference
Lifestyle causes of male infertility
10.1016/j.aju.2017.12.004 · 2018 · External reference
Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility
10.1210/endo.137.11.8895349 · 1996 · External reference
Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics
10.1074/mcp.m113.035600 · 2014 · External reference
Exposure of mice to environmentally relevant per- and polyfluoroalkyl substances (PFAS) alters the sperm epigenome
10.1038/s42003-025-08865-4 · 2025 · External reference
Investigating the “two-hit hypothesis”: effects of prenatal maternal immune activation and adolescent cannabis use on neurodevelopment in mice
10.1016/j.pnpbp.2022.110642 · 2023 · External reference
A framework for high-resolution phenotyping of candidate male infertility mutants: from human to mouse
10.1007/s00439-020-02159-x · 2021 · External reference
DDB1- and CUL4-associated factor 12-like protein 1 (Dcaf12l1) is not essential for male fertility in mice
10.1016/j.ydbio.2022.07.006 · 2022 · External reference
Genetic mutation of Cep76 results in male infertility due to abnormal sperm tail composition
10.26508/lsa.202302452 · 2024 · External reference
The Sertoli cell expressed gene secernin-1 (Scrn1) is dispensable for male fertility in the mouse
10.1002/dvdy.299 · 2021 · External reference
AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans
10.1038/s41419-024-06874-5 · 2024 · External reference
Probing the origins of 1,800 MHz radio frequency electromagnetic radiation induced damage in mouse immortalized germ cells and spermatozoa in vitro
10.3389/fpubh.2018.00270 · 2018 · External reference
The effects of radiofrequency electromagnetic radiation on sperm function
10.1530/rep-16-0126 · 2016 · External reference
Heat exposure induces oxidative stress and DNA damage in the male germ line
10.1093/biolre/ioy009 · 2018 · External reference
Human INHBB gene variant (c.1079T > C: p.Met360Thr) alters testis germ cell content, but does not impact fertility in mice
10.1210/endocr/bqab269 · 2022 · External reference
A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene-disease relationships
10.1093/humupd/dmab030 · 2021 · External reference
Epididymal cysteine-rich secretory proteins are required for epididymal sperm maturation and optimal sperm function
10.1093/molehr/gay001 · 2018 · External reference
Genome sequencing of Pakistani families with male infertility identifies deleterious genotypes in SPAG6, CCDC9, TKTL1, TUBA3C, and M1AP
10.1111/andr.13570 · 2025 · External reference
Frequency, morbidity and equity—the case for increased research on male fertility
10.1038/s41585-023-00820-4 · 2024 · External reference
Impact of chronic multi-generational exposure to an environmentally relevant atrazine concentration on testicular development and function in mice
10.3390/cells12040648 · 2023 · External reference
Genetics of male infertility
10.1038/s41585-018-0003-3 · 2018 · External reference
Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries
10.1093/humupd/dmac035 · 2023 · External reference
Temporal trends in sperm count: a systematic review and meta-regression analysis
10.1093/humupd/dmx022 · 2017 · External reference
M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination
10.15252/embr.202255778 · 2023 · External reference
Diverse monogenic subforms of human spermatogenic failure
10.1038/s41467-022-35661-z · 2022 · External reference
Unresolved reference
2026 · External reference
CCDC89 is required for optimal sperm motility and male fertility in mammals
10.1093/humrep/deaf126 · 2025 · External reference
Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in micedagger
10.1093/biolre/ioad077 · 2023 · External reference
Exome sequencing reveals variants in known and novel candidate genes for severe sperm motility disorders
10.1093/humrep/deab099 · 2021 · External reference
Exome sequencing reveals novel causes as well as new candidate genes for human globozoospermia
10.1093/humrep/dez246 · 2020 · External reference
A de novo paradigm for male infertility
10.1038/s41467-021-27132-8 · 2022 · External reference
Genotype-specific differences in infertile men due to loss-of-function variants in M1AP or ZZS genes
10.1038/s44321-025-00244-0 · 2025 · External reference
A multitude of genes expressed solely in meiotic or postmeiotic spermatogenic cells offers a myriad of contraceptive targets
10.1073/pnas.1635054100 · 2003 · External reference
Environmental factors in declining human fertility
10.1038/s41574-021-00598-8 · 2022 · External reference
Proteomics. Tissue-based map of the human proteome
10.1126/science.1260419 · 2015 · External reference
Unresolved reference
2022 · External reference
Unresolved reference
2025 · External reference
Bi-allelic mutations in M1AP are a frequent cause of meiotic arrest and severely impaired spermatogenesis leading to male infertility
10.1016/j.ajhg.2020.06.010 · 2020 · External reference
A comparative encyclopedia of DNA elements in the mouse genome
10.1038/nature13992 · 2014 · External reference