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References from Granular assessment of paediatric and adolescent ovaries following low levels of alkylating treatment reveals significant morphologic differences in early stage follicles. Local targets link to admitted publications; unresolved targets remain external evidence.
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Unresolved reference
2022 · External reference
Unresolved reference
2025 · External reference
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Impact of first chemotherapy exposure on follicle activation and survival in human cryopreserved ovarian tissue
10.1093/humrep/dead013 · 2023 · External reference
Evidence of cancer therapy-induced chronic inflammation in the ovary across multiple species: a potential cause of persistent tissue damage and follicle depletion
10.1016/j.jri.2022.103491 · 2022 · External reference
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CD34−/CD133+/VEGFR-2+ endothelial progenitor cell subpopulation with potent vasoregenerative capacities
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The cyclophosphamide equivalent dose as an approach for quantifying alkylating agent exposure: a report from the Childhood Cancer Survivor Study
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Proteomic profiling reveals the molecular signatures of chemotherapy-induced human ovarian damage
10.1093/humrep/deaf203 · 2025 · External reference
Morphological study of the ovaries of leukaemic children
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Low doses of alkylating agents do not harm human ovarian tissue destined for cryopreservation
10.1016/j.fertnstert.2024.12.016 · 2025 · External reference
Dobbs v Jackson and access to fertility care among newly diagnosed adolescents and young adults with cancer in the USA
10.1016/s1470-2045(22)00562-9 · 2022 · External reference
Cyclophosphamide triggers follicle activation and “burnout”; AS101 prevents follicle loss and preserves fertility
10.1126/scitranslmed.3005402 · 2013 · External reference
Increased supply from blood vessels promotes the activation of dormant primordial follicles in mouse ovaries
10.1262/jrd.2019-091 · 2020 · External reference
Establishing the baseline: understanding follicle activation morphometrics in multiple mammalian species
10.1093/biolre/ioaf059 · 2025 · External reference
The control of oocyte survival by intrinsic and extrinsic factors
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When to cryopreserve ovarian tissue: determining the effects of chemotherapy on the ovarian reserve by studying follicular density and apoptosis
10.1111/cyt.13194 · 2023 · External reference
Short-term exposure of human ovarian follicles to cyclophosphamide metabolites seems to promote follicular activation in vitro
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Methods for quantifying fibriliar collagen alignment
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Unresolved reference
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Comprehensive fertility preservation can be offered in a timely manner around gonadotoxic therapy in children and adolescents
10.1002/pbc.31232 · 2024 · External reference
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Cortical fibrosis and blood-vessels damage in human ovaries exposed to chemotherapy. Potential mechanisms of ovarian injury
10.1093/humrep/dem027 · 2007 · External reference
Mechanical stress accompanied with nuclear rotation is involved in the dormant state of mouse oocytes
10.1126/sciadv.aav9960 · 2019 · External reference
Effect of previous alkylating agent exposure on follicle numbers in cryopreserved prepubertal and young adult ovarian tissue after long-term xenografting
10.3390/cancers14020399 · 2022 · External reference
Impact of previous chemotherapy on ovarian production of estradiol, progesterone, and AMH: an in vitro controlled study
10.1016/j.fertnstert.2007.07.066 · 2007 · External reference
Quantitative assessment of the impact of chemotherapy on ovarian follicle reserve and stromal function
10.1002/cncr.23071 · 2007 · External reference
Spatiotemporal changes in mechanical matrisome components of the human ovary from prepuberty to menopause
10.1093/humrep/deaa100 · 2020 · External reference
A blueprint of the topology and mechanics of the human ovary for next-generation bioengineering and diagnosis
10.1038/s41467-021-25934-4 · 2021 · External reference
Chemotherapy-related late adverse effects on ovarian function in female survivors of childhood and young adult cancer: a systematic review
10.1016/j.ctrv.2016.11.006 · 2017 · External reference
Impact of first-line cancer treatment on the follicle quality in cryopreserved ovarian samples from girls and young women
10.1093/humrep/dez125 · 2019 · External reference
Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells
10.1007/s10456-012-9321-x · 2013 · External reference
Functional definition of progenitors versus mature endothelial cells reveals key SoxF-dependent differentiation process
10.1161/circulationaha.116.024754 · 2017 · External reference
Impact of cancer chemotherapy before ovarian cortex cryopreservation on ovarian tissue transplantation
10.1093/humrep/dez047 · 2019 · External reference
Angiogenesis and vascular function in the ovary
10.1530/rep-09-0283 · 2009 · External reference
Acute doxorubicin insult in the mouse ovary is cell- and follicle-type dependent
10.1371/journal.pone.0042293 · 2012 · External reference
Unresolved reference
2023 · External reference
Ovaries of patients recently treated with alkylating agent chemotherapy indicate the presence of acute follicle activation, elucidating its role among other proposed mechanisms of follicle loss
10.1016/j.fertnstert.2020.11.040 · 2021 · External reference
Primordial follicle survival and changes in ovarian vasculature may be independently regulated during chemotherapy
10.1210/endocr/bqaf059 · 2025 · External reference
The impact of chemotherapy on the ovaries: molecular aspects and the prevention of ovarian damage
10.3390/ijms20215342 · 2019 · External reference
Endothelial vascular toxicity from chemotherapeutic agents: preclinical evidence and clinical implications
10.1016/j.ctrv.2011.09.002 · 2012 · External reference
Fertility preservation in people with cancer: ASCO guideline update
10.1200/jco-24-02782 · 2025 · External reference
Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans
10.1126/scitranslmed.3004925 · 2013 · External reference
Individual-oocyte transcriptomic analysis shows that genotoxic chemotherapy depletes human primordial follicle reserve in vivo by triggering proapoptotic pathways without growth activation
10.1038/s41598-020-79643-x · 2021 · External reference
Human ovarian gross morphology and subanatomy across puberty: insights from tissue donated during fertility preservation
2023 · External reference
Creating a common language for the subanatomy of the ovary
10.1093/biolre/ioac199 · 2023 · External reference
Doxorubicin obliterates mouse ovarian reserve through both primordial follicle atresia and overactivation
10.1016/j.taap.2019.114714 · 2019 · External reference
A retrospective study of ovarian tissue cryopreservation in female patients with hematological diseases for fertility preservation
10.1007/s00404-024-07484-4 · 2024 · External reference
Physical properties of alginate hydrogels and their effects on in vitro follicle development
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The importance of DNA repair for maintaining oocyte quality in response to anti-cancer treatments, environmental toxins and maternal ageing
10.1093/humupd/dmy002 · 2018 · External reference
Imaging and tracing the pattern of adult ovarian angiogenesis implies a strategy against female reproductive aging
10.1126/sciadv.abi8683 · 2022 · External reference
Classification system of human ovarian follicle morphology: recommendations of the National Institute of Child Health and Human Development—sponsored ovarian nomenclature workshop
10.1016/j.fertnstert.2024.11.016 · 2025 · External reference
Preservation of fertility in teenagers and young adults treated for haematological malignancies
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