Research graph
References from Host Immune Biosignatures Predict Septic Shock and Mortality in Solid Organ Transplant Recipients With Gram-Negative Bacteremia. Local targets link to admitted publications; unresolved targets remain external evidence.
Bacterial and fungal bloodstream infections in solid organ transplant recipients: results from a Danish cohort with nationwide follow-up
10.1016/j.cmi.2021.07.021 · 2022 · External reference
Gram-negative bacteremia in solid organ transplant recipients: clinical characteristics and outcomes as compared to immunocompetent non-transplant recipients
10.1111/tid.13969 · 2022 · External reference
Sepsis in patients who are immunocompromised: diagnostic challenges and future therapies
10.1016/s2213-2600(25)00124-9 · 2025 · External reference
Factors influencing mortality in solid organ transplant recipients with bloodstream infection
10.1016/j.cmi.2015.07.021 · 2015 · External reference
Bloodstream infection subtypes and characteristics comparing solid organ transplant and non-transplant populations
10.1016/j.ajt.2025.10.019 · 2026 · External reference
Immunosuppressive agents and infectious risk in transplantation: managing the “net state of immunosuppression.”
10.1093/cid/ciaa1189 · 2021 · External reference
Steroid-induced secondary immune deficiency
10.1016/j.anai.2023.01.010 · 2023 · External reference
Bacteremia in solid organ transplant recipients as compared to immunocompetent patients: acute phase cytokines and outcomes in a prospective, matched cohort study
10.1111/ajt.16388 · 2021 · External reference
Calcineurin inhibitors suppress cytokine production from memory T cells and differentiation of naïve T cells into cytokine-producing mature T cells
10.1371/journal.pone.0031465 · 2012 · External reference
Immune regulation by glucocorticoids
10.1038/nri.2017.1 · 2017 · External reference
Cyclosporine and tacrolimus have inhibitory effects on toll-like receptor signaling after liver transplantation
10.1002/lt.23712 · 2013 · External reference
Calcineurin inhibitors dampen humoral immunity by acting directly on naive B cells
10.1111/cei.12604 · 2015 · External reference
American College of Chest Physicians/Society of Critical Care medicine consensus conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
10.1097/00003246-199206000-00025 · 1992 · External reference
The use of multiple imputation for data subject to limits of detection
10.4038/sljastats.v5i4.7792 · 2014 · External reference
Unresolved reference
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The choice of methods in determining the optimal cut-off value for quantitative diagnostic test evaluation
10.1177/0962280216680383 · 2018 · External reference
Pathogen recognition and inflammatory signaling in innate immune defenses
10.1128/cmr.00046-08 · 2009 · External reference
The role of endothelial interleukin-8/NADPH oxidase 1 axis in sepsis
10.1111/j.1365-2567.2010.03303.x · 2010 · External reference
Prognostic value of monocyte chemoattractant protein-1 in sepsis: a systematic review and meta-analysis
10.1186/s12865-025-00783-8 · 2025 · External reference
Interleukin-6 in sepsis and capillary leakage syndrome
10.1089/jir.2011.0062 · 2012 · External reference
The interleukin network in sepsis: from cytokine storm to clinical applications
10.3390/diagnostics15222927 · 2025 · External reference
Interleukin-2 production by dendritic cells and its immuno-regulatory functions
10.3389/fimmu.2012.00161 · 2012 · External reference
Recent advances in the biology of IL-1 family cytokines and their potential roles in development of sepsis
10.1016/j.cytogfr.2018.12.004 · 2019 · External reference
Cytokines in sepsis: a critical review of the literature on systemic inflammation and multiple organ dysfunction
10.3389/fimmu.2025.1682306 · 2025 · External reference
Interleukin-2 inhibits germinal center formation by limiting T follicular helper cell differentiation
10.1016/j.immuni.2012.02.012 · 2012 · External reference
Foxp3+ regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availability
10.1038/ncomms4495 · 2014 · External reference
The regulation of IL-10 production by immune cells
10.1038/nri2711 · 2010 · External reference
Role of cytokines as a double-edged sword in sepsis
2013 · External reference
The regulation of IL-10 expression
2014 · External reference
Independent protective effects for tumor necrosis factor and lymphotoxin alpha in the host response to Listeria monocytogenes infection
10.1128/iai.73.8.4787-4792.2005 · 2005 · External reference
Current and future clinical applications of interferon-gamma in host antimicrobial defense
10.1007/bf01743724 · 1996 · External reference
Low immunoglobulin G level is associated with poor outcomes in patients with sepsis and septic shock
10.1016/j.jmii.2020.08.013 · 2021 · External reference
Lung IFNAR1hi TNFR2 + cDC2 promotes lung regulatory T cells induction and maintains lung mucosal tolerance at steady state
10.1038/s41385-020-0254-1 · 2020 · External reference
Tissue-resident immunity in the lung: a first-line defense at the environmental interface
10.1007/s00281-022-00964-2 · 2022 · External reference
Calcineurin inhibitors affect B cell antibody responses indirectly by interfering with T cell help
10.1111/j.1365-2249.2009.04051.x · 2010 · External reference
The calcineurin inhibitor tacrolimus specifically suppresses human T follicular helper cells
10.3389/fimmu.2018.01184 · 2018 · External reference
Effects of FK506 and cyclosporin A on cytokine production studied in vitro at a single-cell level
1992 · External reference
In vitro cytokine responses in liver transplant recipients treated with cyclosporine A and tacrolimus
10.1111/j.1399-0012.2009.01114.x · 2009 · External reference
Mycophenolate mofetil-based immunosuppression and cytokine genotypes: effects on monokine secretion and antigen presentation in long-term renal transplant recipients
10.1097/01.tp.0000058808.37349.23 · 2003 · External reference
Mycophenolate mofetil-induced hypogammaglobulinemia and infectious disease susceptibility in pediatric patients with chronic rheumatic disorders: a monocentric retrospective study
10.1007/s00431-022-04560-2 · 2022 · External reference
Mycophenolic acid-mediated suppression of human CD4+ T cells: more than mere guanine nucleotide deprivation
10.1111/j.1600-6143.2010.03413.x · 2011 · External reference
Mycophenolic acid suppresses granulopoiesis by inhibition of interleukin-17 production
10.1038/ki.2010.84 · 2010 · External reference
Antiinflammatory action of glucocorticoids—new mechanisms for old drugs
10.1056/nejmra050541 · 2005 · External reference
Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study
10.1016/s2213-2600(17)30294-1 · 2017 · External reference
Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study
10.1016/s2213-2600(16)00046-1 · 2016 · External reference
