References

In vitro bactericidal capacity of human polymorphonuclear leukocytes: diminished activity in chronic granulomatous disease of childhood

10.1172/jci105568 · 1967 · External reference

Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent

10.1172/jci107236 · 1973 · External reference

Arginine-rich proteins of polymorphonuclear leukocyte lysosomes. Antimicrobial specificity and biochemical heterogeneity

10.1084/jem.127.5.927 · 1968 · External reference

Intracellular and extracellular degranulation of human polymorphonuclear azurophil and specific granules induced by immune complexes

10.1128/iai.10.6.1241-1249.1974 · 1974 · External reference

Major cell types in the coronary thrombosis of acute myocardial infarction patients revealed by scRNA-seq

10.1002/ctm2.70181 · 2025 · External reference

Circulating human peripheral blood granulocytes synthesize and secrete tumor necrosis factor alpha

10.1073/pnas.87.17.6758 · 1990 · External reference

Phagocytosing neutrophils produce and release high amounts of the neutrophil-activating peptide 1/interleukin 8

10.1084/jem.173.3.771 · 1991 · External reference

Neutrophil extracellular traps kill bacteria

10.1126/science.1092385 · 2004 · External reference

Neutrophil extracellular traps in immunity and disease

10.1038/nri.2017.105 · 2018 · External reference

Neutrophil granulocyte-committed cells can be driven to acquire dendritic cell characteristics

10.1084/jem.187.7.1019 · 1998 · External reference

B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

10.1038/ni.2194 · 2011 · External reference

APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa

10.1172/jci33760 · 2008 · External reference

Suppression of T-cell functions by human granulocyte arginase

10.1182/blood-2006-11-010389 · 2006 · External reference

Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus

10.4049/jimmunol.1100450 · 2011 · External reference

Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients

10.1186/cc14003 · 2014 · External reference

Phenotypic diversity and plasticity in circulating neutrophil subpopulations in cancer

10.1016/j.celrep.2014.12.039 · 2015 · External reference

Mature CD10(+) and immature CD10(-) neutrophils present in G-CSF-treated donors display opposite effects on T cells

10.1182/blood-2016-04-713206 · 2017 · External reference

Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients

10.1126/sciimmunol.aaf8943 · 2016 · External reference

Target neutrophil heterogeneity and plasticity in cancer

10.1186/s13045-025-01731-0 · 2025 · External reference

RNA-Seq signatures normalized by mRNA abundance allow absolute deconvolution of human immune cell types

10.1016/j.celrep.2019.01.041 · 2019 · External reference

Optimization of methods for the accurate characterization of whole blood neutrophils

10.1038/s41598-022-07455-2 · 2022 · External reference

Ribonuclease activity associated with human eosinophil-derived neurotoxin and eosinophil cationic protein

10.4049/jimmunol.137.9.2913 · 1986 · External reference

Cryopreservation of human granulocytes in liquid nitrogen

10.1136/jcp.30.8.758 · 1977 · External reference

Comparison of single-cell RNA-seq methods to enable transcriptome profiling of neutrophils in clinical samples

10.1016/j.crmeth.2025.101173 · 2025 · External reference

Massively parallel digital transcriptional profiling of single cells

10.1038/ncomms14049 · 2017 · External reference

Abseq protocol using the nano-well cartridge-based rhapsody platform to generate protein and transcript expression data on the single-cell level

10.1016/j.xpro.2020.100092 · 2020 · External reference

High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer

10.1016/j.ccell.2022.10.008 · 2022 · External reference

Comparative analysis of 10X Chromium vs. BD Rhapsody whole transcriptome single-cell sequencing technologies in complex human tissues

10.1016/j.heliyon.2024.e28358 · 2024 · External reference

Integrated analysis of multimodal single-cell data

10.1016/j.cell.2021.04.048 · 2021 · External reference

Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection

10.1038/s41590-020-0736-z · 2020 · External reference

Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress

10.1038/s41590-022-01311-1 · 2022 · External reference

CD66b(-)CD64(dim)CD115(-) cells in the human bone marrow represent neutrophil-committed progenitors

10.1038/s41590-022-01189-z · 2022 · External reference

Primitive genotypic characteristics in umbilical cord neutrophils identified by single-cell transcriptome profiling and functional prediction

10.3389/fimmu.2022.970909 · 2022 · External reference

Uncovering common transcriptional features shared by mature peripheral blood PMN-MDSCs and tumor-infiltrating neutrophils in humans

10.1080/2162402x.2025.2521396 · 2025 · External reference

Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus

10.1073/pnas.1908576116 · 2019 · External reference

Neutrophil single-cell analysis identifies a type II interferon-related subset for predicting relapse of autoimmune small vessel vasculitis

10.1038/s41467-025-58550-7 · 2025 · External reference

Sex-specific circulating unconventional neutrophils determine immunological outcome of auto-inflammatory Behcet's uveitis

10.1038/s41421-024-00671-2 · 2024 · External reference

Spatiotemporal transcriptomics deciphered neutrophil-activated interleukin-36 as driver and effective therapeutic target in sweet syndrome

10.1093/bjd/ljaf396 · 2026 · External reference

Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease

10.1038/s41467-023-40156-6 · 2023 · External reference

Single cell RNA sequencing of human eosinophils from nasal polyps reveals eosinophil heterogeneity in chronic rhinosinusitis tissue

10.1016/j.jaci.2024.05.014 · 2024 · External reference

ALOX15(+) M2 macrophages contribute to epithelial remodeling in eosinophilic chronic rhinosinusitis with nasal polyps

10.1016/j.jaci.2024.04.019 · 2024 · External reference

Analysis of human neutrophils from nasal polyps by single-cell RNA sequencing reveals roles of neutrophils in chronic rhinosinusitis

10.1016/j.jaci.2024.10.032 · 2025 · External reference

Single-cell RNA sequencing of human blood eosinophils reveals plasticity and absence of canonical cell subsets

10.1111/all.16213 · 2025 · External reference

Multi-scaled transcriptomics of chronically inflamed nasal epithelium reveals immune-epithelial dynamics and tissue remodeling in nasal polyp formation

10.1016/j.immuni.2025.08.009 · 2025 · External reference

Severe COVID-19 is marked by a dysregulated myeloid cell compartment

10.1016/j.cell.2020.08.001 · 2020 · External reference

Heterogeneity of neutrophils and inflammatory responses in patients with COVID-19 and healthy controls

10.3389/fimmu.2022.970287 · 2022 · External reference

Global absence and targeting of protective immune states in severe COVID-19

10.1038/s41586-021-03234-7 · 2021 · External reference

Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19

10.1038/s41591-021-01576-3 · 2022 · External reference

Transcriptional reprogramming of infiltrating neutrophils drives lung pathology in severe COVID-19 despite low viral load

10.1182/bloodadvances.2022008834 · 2023 · External reference

Lower respiratory tract single-cell RNA sequencing and neutrophil extracellular trap profiling of COVID-19-associated pulmonary aspergillosis: a single centre, retrospective, observational study

10.1016/s2666-5247(23)00368-3 · 2024 · External reference

Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis

10.1038/s41590-023-01490-5 · 2023 · External reference

Single-cell landscape of bronchoalveolar lavage fluid identifies specific neutrophils during septic immunosuppression

10.1002/advs.202406218 · 2025 · External reference

Single-cell transcriptome profiling reveals heterogeneous neutrophils with prognostic values in sepsis

10.1016/j.isci.2022.105301 · 2022 · External reference

Single-cell atlas of human gingiva unveils a NETs-related neutrophil subpopulation regulating periodontal immunity

10.1016/j.jare.2024.07.028 · 2025 · External reference

Neutrophils as regulators of cardiovascular inflammation

10.1038/s41569-019-0326-7 · 2020 · External reference

Thrombosis as an intravascular effector of innate immunity

10.1038/nri3345 · 2013 · External reference

MMP9(High) neutrophils are critical mediators of neutrophil extracellular traps formation and myocardial ischemia/reperfusion injury

10.1002/advs.202415205 · 2025 · External reference

Neutrophil extracellular traps in ischemia-reperfusion injury-induced myocardial no-reflow: therapeutic potential of DNase-based reperfusion strategy

10.1152/ajpheart.00381.2014 · 2015 · External reference

Integration of bulk RNA-seq and scRNA-Seq reveals transcriptomic signatures associated with deep vein thrombosis

10.3389/fgene.2025.1551879 · 2025 · External reference

Single-cell transcriptome analysis of peripheral neutrophils from patients with idiopathic pulmonary arterial hypertension

10.1161/hypertensionaha.123.21142 · 2023 · External reference

Biologics for chronic rhinosinusitis with nasal polyps

10.1016/j.jaci.2020.01.020 · 2020 · External reference

From complexity to consensus: a roadmap for neutrophil classification

10.1016/j.immuni.2025.07.011 · 2025 · External reference

Architecture of the neutrophil compartment

10.1038/s41586-025-09807-0 · 2026 · External reference

Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses

10.1038/s41467-023-36325-2 · 2023 · External reference