References

Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

10.3322/caac.21834 · 2024 · External reference

Global disparities of cancer and its projected burden in 2050

10.1001/jamanetworkopen.2024.43198 · 2024 · External reference

Lessons from functional analysis of genome-wide association studies

10.1158/0008-5472.can-13-0789 · 2013 · External reference

Demystifying non-coding GWAS variants: an overview of computational tools and methods

10.1093/hmg/ddac198 · 2022 · External reference

Towards functional maps of non-coding variants in cancer

10.3389/fgeed.2024.1481443 · 2024 · External reference

Cell type-specific genetic regulation of gene expression across human tissues

10.1126/science.aaz8528 · 2020 · External reference

Mechanisms of tissue and cell-type specificity in heritable traits and diseases

10.1038/s41576-019-0200-9 · 2020 · External reference

The evolving tumor microenvironment: from cancer initiation to metastatic outgrowth

10.1016/j.ccell.2023.02.016 · 2023 · External reference

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1

10.1016/j.ajhg.2013.10.026 · 2013 · External reference

Context-aware single-cell multiomics approach identifies cell-type-specific lung cancer susceptibility genes

10.1038/s41467-024-52356-9 · 2024 · External reference

Partitioning heritability by functional annotation using genome-wide association summary statistics

10.1038/ng.3404 · 2015 · External reference

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

10.1038/s41588-018-0081-4 · 2018 · External reference

Characterization of single-cell cis-regulatory elements informs implications for cell differentiation

10.1093/gbe/evae241 · 2024 · External reference

Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions

10.1101/gr.152140.112 · 2013 · External reference

Linkage disequilibrium dependent architecture of human complex traits shows action of negative selection

10.1038/ng.3954 · 2017 · External reference

Modeling tissue co-regulation estimates tissue-specific contributions to disease

10.1038/s41588-023-01474-z · 2023 · External reference

10.1101/2024.05.17.24307556

10.1101/2024.05.17.24307556 · 2024 · External reference

Functionally informed fine-mapping and polygenic localization of complex trait heritability

10.1038/s41588-020-00735-5 · 2020 · External reference

An expanded registry of candidate cis-regulatory elements

10.1038/s41586-025-09909-9 · 2026 · External reference

A single-cell atlas of chromatin accessibility in the human genome

10.1016/j.cell.2021.10.024 · 2021 · External reference

Genome-wide enhancer maps link risk variants to disease genes

10.1038/s41586-021-03446-x · 2021 · External reference

Regulatory genomic circuitry of human disease loci by integrative epigenomics

10.1038/s41586-020-03145-z · 2021 · External reference

The chromatin accessibility landscape of primary human cancers

10.1126/science.aav1898 · 2018 · External reference

Association analysis identifies 65 new breast cancer risk loci

10.1038/nature24284 · 2017 · External reference

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

10.1038/ng.3826 · 2017 · External reference

Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants

10.1038/s41588-023-01534-4 · 2023 · External reference

Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

10.1038/s41588-022-01222-9 · 2023 · External reference

Genome-wide association studies in oesophageal adenocarcinoma and Barrett’s oesophagus: a large-scale meta-analysis

10.1016/s1470-2045(16)30240-6 · 2016 · External reference

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

10.1038/ng.3892 · 2017 · External reference

Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions

10.1038/s41588-024-01725-7 · 2024 · External reference

Genome-wide association study of bladder cancer reveals new biological and translational insights

10.1016/j.eururo.2023.04.020 · 2023 · External reference

GWAS meta-analysis identifies five susceptibility loci for endometrial cancer

10.1016/j.ebiom.2025.105830 · 2025 · External reference

A simple new approach to variable selection in regression, with application to genetic fine mapping

10.1111/rssb.12388 · 2020 · External reference

Fine-mapping from summary data with the “sum of single effects” model

10.1371/journal.pgen.1010299 · 2022 · External reference

Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity

10.1038/s41588-022-01087-y · 2022 · External reference

Position-dependent function of human sequence-specific transcription factors

10.1038/s41586-024-07662-z · 2024 · External reference

FORGEdb: a tool for identifying candidate functional variants and uncovering target genes and mechanisms for complex diseases

10.1186/s13059-023-03126-1 · 2024 · External reference

Shared genetics of lung cancer and type 2 diabetes: a large-scale genome-wide cross-trait analysis

10.21037/tlcr-2025-184/prf · 2025 · External reference

Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility

10.7554/elife.95720 · 2024 · External reference

Luminal epithelial cells within the mammary gland can produce basal cells upon oncogenic stress

10.1038/onc.2015.206 · 2016 · External reference

Germline variants that affect tumor progression

10.1016/j.tig.2020.10.005 · 2021 · External reference

Genomic hallmarks and structural variation in metastatic prostate cancer

10.1016/j.cell.2018.06.039 · 2018 · External reference

Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer

10.1016/j.cell.2018.03.022 · 2018 · External reference

Development of the human prostate

10.1016/j.diff.2018.08.005 · 2018 · External reference

Multi-variant pathway association analysis reveals the importance of genetic determinants of estrogen metabolism in breast and endometrial cancer susceptibility

10.1371/journal.pgen.1001012 · 2010 · External reference

LINC-PINT suppresses breast cancer cell proliferation and migration via MEIS2/PPP3CC/NF-κB pathway by sponging miR-576-5p

10.1016/j.amjms.2023.08.013 · 2024 · External reference

CRR9/CLPTM1L regulates cell survival signaling and is required for ras transformation and lung tumorigenesis

10.1158/0008-5472.can-13-1617 · 2014 · External reference

The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling

10.1038/s41467-022-32472-0 · 2022 · External reference

TNS1: emerging insights into its domain function, biological roles, and tumors

10.3390/biology11111571 · 2022 · External reference

The prostatic acid phosphatase (acpp) gene is localized to human chromosome 3q21-q23

10.1006/geno.1993.1403 · 1993 · External reference

The GTEx Consortium atlas of genetic regulatory effects across human tissues

10.1126/science.aaz1776 · 2020 · External reference

Long noncoding RNA KCNQ1OT1 is a prognostic biomarker and mediates CD8+ T cell exhaustion by regulating CD155 expression in colorectal cancer

10.7150/ijbs.59001 · 2021 · External reference

Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility

10.1073/pnas.0902104106 · 2009 · External reference

Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression

10.1038/ng.2416 · 2012 · External reference

Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148

10.1038/ncomms15034 · 2017 · External reference

Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases

10.1038/s41588-024-01870-z · 2024 · External reference