Research graph
References from The NORAD -Pumilio regulatory axis in the evolution of inclusion body myositis. Local targets link to admitted publications; unresolved targets remain external evidence.
Epidemiology of sporadic inclusion body myositis and polymyositis in Olmsted County, Minnesota
2008 · External reference
Epidemiology and natural history of inclusion body myositis: a 40-year population-based study
10.1212/wnl.0000000000012004 · 2021 · External reference
Long-term observational study of sporadic inclusion body myositis
10.1093/brain/awr213 · 2011 · External reference
Amyloid filaments in inclusion body myositis. Novel findings provide insight into nature of filaments
10.1001/archneur.1991.00530240033013 · 1991 · External reference
Inclusion body myositis and myopathies
10.1002/ana.410380504 · 1995 · External reference
Pathogenic considerations in sporadic inclusion-body myositis, a degenerative muscle disease associated with aging and abnormalities of myoproteostasis
10.1097/nen.0b013e31826183c8 · 2012 · External reference
A retrospective cohort study identifying the principal pathological features useful in the diagnosis of inclusion body myositis
10.1136/bmjopen-2013-004552 · 2014 · External reference
Functional relevance of mitochondrial abnormalities in sporadic inclusion body myositis
10.1016/j.jocn.2014.05.051 · 2014 · External reference
Sporadic inclusion body myositis: an acquired mitochondrial disease with extras
10.3390/biom9010015 · 2019 · External reference
Mitochondrial DNA depletion in sporadic inclusion body myositis
10.1016/j.nmd.2019.02.001 · 2019 · External reference
Multiple mitochondrial DNA deletions in sporadic inclusion body myositis: a study of 56 patients
10.1002/ana.410390615 · 1996 · External reference
Mitochondrial DNA variants in inclusion body myositis characterized by deep sequencing
10.1111/bpa.12931 · 2021 · External reference
Light and electron microscopic immunolocalization of presenilin 1 in abnormal muscle fibers of patients with sporadic inclusion-body myositis and autosomal-recessive inclusion-body myopathy
1998 · External reference
Sporadic inclusion-body myositis and its similarities to Alzheimer disease brain. Recent approaches to diagnosis and pathogenesis, and relation to aging
10.1080/030097498442208 · 1998 · External reference
Sporadic inclusion-body myositis: conformational multifactorial ageing-related degenerative muscle disease associated with proteasomal and lysosomal inhibition, endoplasmic reticulum stress, and accumulation of amyloid-beta42 oligomers and phosphorylated tau
10.1016/j.lpm.2010.11.024 · 2011 · External reference
Immune and myodegenerative pathomechanisms in inclusion body myositis
10.1002/acn3.419 · 2017 · External reference
Inclusion body myositis: update on pathogenesis and treatment
10.1007/s13311-018-0658-8 · 2018 · External reference
Pathogenesis of inclusion body myositis
10.1097/bor.0000000000000752 · 2020 · External reference
Biologically stressed muscle fibers in sporadic IBM: a clue for the enigmatic etiology?
10.1212/wnl.54.5.1020 · 2000 · External reference
Proinflammatory cell stress in sporadic inclusion body myositis muscle: overexpression of alphaB-crystallin is associated with amyloid precursor protein and accumulation of beta-amyloid
10.1136/jnnp.2009.174276 · 2009 · External reference
Autoantibodies to cytosolic 5'-nucleotidase 1A in inclusion body myositis
10.1002/ana.23822 · 2013 · External reference
Sporadic inclusion-body myositis: a degenerative muscle disease associated with aging, impaired muscle protein homeostasis and abnormal mitophagy
10.1016/j.bbadis.2014.09.005 · 2015 · External reference
Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis
10.1126/scitranslmed.abi9196 · 2022 · External reference
Follistatin gene therapy for sporadic inclusion body myositis improves functional outcomes
10.1016/j.ymthe.2017.02.015 · 2017 · External reference
Noncoding RNA NORAD regulates genomic stability by sequestering PUMILIO proteins
10.1016/j.cell.2015.12.017 · 2016 · External reference
PUMILIO hyperactivity drives premature aging of Norad-deficient mice
10.7554/elife.42650 · 2019 · External reference
NORAD-induced Pumilio phase separation is required for genome stability
10.1038/s41586-021-03633-w · 2021 · External reference
Post-transcriptional regulatory functions of mammalian Pumilio proteins
10.1016/j.tig.2018.09.006 · 2018 · External reference
Simultaneous multicolor detection of RNA and proteins using super-resolution microscopy
10.1016/j.ymeth.2015.11.007 · 2016 · External reference
Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone
10.1093/hmg/ddq050 · 2010 · External reference
Inclusion-body myositis: muscle-fiber molecular pathology and possible pathogenic significance of its similarity to Alzheimer’s and Parkinson’s disease brains
10.1007/s00401-008-0449-0 · 2008 · External reference
Inclusion body myositis: a degenerative muscle disease associated with intra-muscle fiber multi-protein aggregates, proteasome inhibition, endoplasmic reticulum stress and decreased lysosomal degradation
10.1111/j.1750-3639.2009.00290.x · 2009 · External reference
Sporadic inclusion body myositis at the crossroads between muscle degeneration, inflammation, and aging
10.3390/ijms25052742 · 2024 · External reference
The mitochondrial basis of aging
10.1016/j.molcel.2016.01.028 · 2016 · External reference
Premature ageing in mice expressing defective mitochondrial DNA polymerase
10.1038/nature02517 · 2004 · External reference
Post-transcriptional regulation of mouse neurogenesis by Pumilio proteins
10.1101/gad.298752.117 · 2017 · External reference
Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels
10.1016/j.cell.2015.02.012 · 2015 · External reference
A mild PUM1 mutation is associated with adult-onset ataxia, whereas haploinsufficiency causes developmental delay and seizures
10.1016/j.cell.2018.02.006 · 2018 · External reference
The RNA-binding protein PUM2 impairs mitochondrial dynamics and mitophagy during aging
10.1016/j.molcel.2018.11.034 · 2019 · External reference
RNA binding protein PUM2 promotes IL-1beta-induced apoptosis of chondrocytes via regulating FOXO3 expression
10.1016/j.heliyon.2024.e25080 · 2024 · External reference
Muscle biopsies from human muscle diseases with myopathic pathology reveal common alterations in mitochondrial function
10.1111/jnc.13626 · 2016 · External reference
IFN-beta-induced reactive oxygen species and mitochondrial damage contribute to muscle impairment and inflammation maintenance in dermatomyositis
10.1007/s00401-017-1731-9 · 2017 · External reference
Perifascicular atrophic fibers in childhood dermatomyositis with particular reference to mitochondrial changes
10.1016/0022-510x(88)90211-0 · 1988 · External reference
Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels
10.1016/j.neuron.2013.02.028 · 2013 · External reference
Valosin-containing protein (VCP/p97) inhibitors relieve Mitofusin-dependent mitochondrial defects due to VCP disease mutants
10.7554/elife.17834 · 2017 · External reference
