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References from Effects of phytocannabinoids, synthetic and semi-synthetic cannabinoids on microglia and astrocytes: Review of neuroinflammatory mechanisms. Local targets link to admitted publications; unresolved targets remain external evidence.
Long-term hippocampal glutamate synapse and astrocyte dysfunctions underlying the altered phenotype induced by adolescent THC treatment in male rats
10.1016/j.phrs.2016.07.008 · 2016 · External reference
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2025 · External reference
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2025 · External reference
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2026 · External reference
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2023 · External reference
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2024 · External reference
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2025 · External reference
The effects of cannabinoids on executive functions: evidence from cannabis and synthetic cannabinoids-a systematic review
10.3390/brainsci8030040 · 2018 · External reference
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2026 · External reference
Endocannabinoid-mediated control of synaptic transmission
10.1152/physrev.00019.2008 · 2009 · External reference
Molecular characterization of a peripheral receptor for cannabinoids
10.1038/365061a0 · 1993 · External reference
Identification and functional characterization of brainstem cannabinoid CB2 receptors
10.1126/science.1115740 · 2005 · External reference
Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli
10.1111/j.1471-4159.2005.03380.x · 2005 · External reference
Epilepsy and astrocyte energy metabolism
10.1002/glia.23247 · 2018 · External reference
Cellular specificity and inter-cellular coordination in the brain bioenergetic system: implications for aging and neurodegeneration
10.3389/fphys.2019.01531 · 2019 · External reference
Reciprocal interactions between microglia and neurons: from survival to neuropathology
10.1515/revneuro.2002.13.3.221 · 2002 · External reference
Exposure of adolescent mice to Delta-9-tetrahydrocannabinol induces long-lasting modulation of pro- and anti-inflammatory cytokines in hypothalamus and hippocampus similar to that observed for peripheral macrophages
10.1007/s11481-015-9592-2 · 2015 · External reference
Microglia: intrinsic immuneffector cell of the brain
10.1016/0165-0173(94)00015-h · 1995 · External reference
Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes
10.1186/s40035-020-00221-2 · 2020 · External reference
Identification of glial cell proliferation in early multiple sclerosis lesions
10.1046/j.1365-2990.1998.00131.x · 1998 · External reference
Role of microglia in senile plaque formation
10.1016/0197-4580(95)00092-s · 1995 · External reference
Macrophages/microglia and the pathophysiology of CNS injuries in AIDS
10.1002/jlb.56.3.387 · 1994 · External reference
Microglia in diseases of the central nervous system
10.1080/078538902321117698 · 2002 · External reference
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2026 · External reference
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2025 · External reference
Dementia prevalence and risk factors in people with and without HIV in Malawi: a medical record review
10.1002/alz.70009 · 2025 · External reference
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2023 · External reference
Antioxidant and neuroprotective effects induced by cannabidiol and cannabigerol in rat CTX-TNA2 astrocytes and isolated cortexes
10.3390/ijms21103575 · 2020 · External reference
Microglial activation underlies cerebellar deficits produced by repeated cannabis exposure
10.1172/jci67569 · 2013 · External reference
Anti-inflammatory effects of the cannabidiol derivative dimethylheptyl-cannabidiol - studies in BV-2 microglia and encephalitogenic T cells
10.1515/jbcpp-2015-0071 · 2016 · External reference
Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide
10.1002/glia.10177 · 2003 · External reference
MAM-2201, one of the most potent-naphthoyl indole derivative-synthetic cannabinoids, exerts toxic effects on human cell-based models of neurons and astrocytes
10.1007/s12640-021-00369-3 · 2021 · External reference
Δ9-tetrahydrocannabinol suppresses monocyte-mediated astrocyte production of monocyte chemoattractant protein 1 and interleukin-6 in a toll-like receptor 7-stimulated human coculture
10.1124/jpet.119.260661 · 2019 · External reference
Human astrocyte spheroids as suitable in vitro screening model to evaluate synthetic cannabinoid MAM2201-induced effects on CNS
10.3390/ijms24021421 · 2023 · External reference
Neuronal and astrocytic morphological alterations driven by prolonged exposure with Δ9-tetrahydrocannabinol but not cannabidiol
10.3390/toxics10020048 · 2022 · External reference
Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation
10.1186/1742-2094-2-29 · 2005 · External reference
Cannabisin F from hemp (Cannabis sativa) seed suppresses lipopolysaccharide-induced inflammatory responses in BV2 microglia as SIRT1 modulator
10.3390/ijms20030507 · 2019 · External reference
Immune and glial cell alterations in the rat brain after repeated exposure to the synthetic cannabinoid JWH-018
10.1016/j.jneuroim.2024.578325 · 2024 · External reference
The phenylpropionamide extract of hemp (Cannabis sativa L.) seed improves learning memory ability and survival rate by attenuating microglia activation and reducing amyloid deposition via the SIRT1-AMAD10 pathway in APP/PS1 mice
10.1016/j.phyplu.2024.100573 · 2024 · External reference
Cannabidiol prevents LPS-induced inflammation by inhibiting the NLRP3 inflammasome and iNOS activity in BV2 microglia cells via CB2 receptors and PPARγ
10.1016/j.neuint.2024.105769 · 2024 · External reference
The two synthetic cannabinoid compounds 4’-F-CBD and HU-910 efficiently restrain inflammatory responses of brain microglia and astrocytes
10.1002/glia.24489 · 2024 · External reference
Synthetic cannabinoids reduce the inflammatory activity of microglia and subsequently improve neuronal survival in vitro
10.1016/j.bbi.2022.06.011 · 2022 · External reference
Non-psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors-, endocannabinoids-, and NF-κB-mediated signaling
10.1002/ptr.7458 · 2022 · External reference
Δ9-tetrahydrocannabinol (THC) impairs CD8+ T cell-mediated activation of astrocytes
10.1007/s11481-020-09912-z · 2020 · External reference
Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia
10.1371/journal.pone.0251677 · 2021 · External reference
Abnormal cannabidiol affects production of pro-inflammatory mediators and astrocyte wound closure in primary astrocytic-microglial cocultures
2020 · External reference
Cannabidiol prevents LPS-induced microglial inflammation by inhibiting ROS/NF-κB-dependent signaling and glucose consumption
10.1002/glia.23738 · 2020 · External reference
Cannabinoids prevent lipopolysaccharide-induced neurodegeneration in the rat substantia nigra in vivo through inhibition of microglial activation and NADPH oxidase
10.1016/j.brainres.2012.02.058 · 2012 · External reference
Anti-neuroinflammatory activity of a novel cannabinoid derivative by inhibiting the NF-κB signaling pathway in lipopolysaccharide-induced BV-2 microglial cells
10.1254/jphs.12170fp · 2013 · External reference
Cannabinoids prevent the opposite regulation of astroglial connexin43 hemichannels and gap junction channels induced by pro-inflammatory treatments
10.1111/j.1471-4159.2009.06407.x · 2009 · External reference
Prolonged oral cannabinoid administration prevents neuroinflammation, lowers β-amyloid levels and improves cognitive performance in Tg APP 2576 mice
10.1186/1742-2094-9-8 · 2012 · External reference
Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice
10.1111/j.1476-5381.2011.01379.x · 2011 · External reference
Cannabinoid effects on β amyloid fibril and aggregate formation, neuronal and microglial-activated neurotoxicity in vitro
10.1007/s10571-013-9984-x · 2014 · External reference
A cannabigerol quinone alleviates neuroinflammation in a chronic model of multiple sclerosis
10.1007/s11481-012-9399-3 · 2012 · External reference
Cannabinoids attenuate the effects of aging upon neuroinflammation and neurogenesis
10.1016/j.nbd.2009.01.014 · 2009 · External reference
Microglia states and nomenclature: a field at its crossroads
10.1016/j.neuron.2022.10.020 · 2022 · External reference
