References

Global prevalence of hyperuricemia: a systematic review of population-based epidemiological studies

2015 · External reference

Comparative efficacy and safety of urate-lowering therapy for the treatment of hyperuricemia: a systematic review and network meta-analysis

10.1038/srep33082 · 2016 · External reference

The effect of mild hyperuricemia on urinary transforming growth factor beta and the progression of chronic kidney disease

10.1159/000105142 · 2007 · External reference

Hypersensitivity and cardiovascular risks related to allopurinol and febuxostat therapy in asians: a population-based cohort study and meta-analysis

10.1002/cpt.1377 · 2019 · External reference

Gout

10.1016/s0140-6736(21)00569-9 · 2021 · External reference

Research progress in the mechanism of traditional Chinese medicine and natural products for hyperuricemia and gout

2024 · External reference

A brief analysis of the current clinical application status of Shuxuening injection

2017 · External reference

Observation on 30 cases of nephrotic syndrome complicated with acute renal insufficiency treated by prednisone combined with Shuxuening injection

2014 · External reference

Efficacy and safety of Shuxuening injection as an adjuvant therapy for patients with diabetic nephropathy

2025 · External reference

Discovery of the mechanisms and major bioactive compounds responsible for the protective effects of Gualou Xiebai decoction on coronary heart disease by network pharmacology analysis

10.1016/j.phymed.2018.11.010 · 2019 · External reference

Network pharmacology databases for traditional Chinese medicine: review and assessment

10.3389/fphar.2019.00123 · 2019 · External reference

Mass spectrometry-based metabolomics in microbiome investigations

10.1038/s41579-021-00621-9 · 2022 · External reference

Anti-Alzheimers molecular mechanism of icariin: insights from gut microbiota, metabolomics, and network pharmacology

10.1186/s12967-023-04137-z · 2023 · External reference

Unresolved reference

2020 · External reference

Analysis of chemical components of ginkgo biloba leaves based on UPLC-Q-TOF-MS technology

2025 · External reference

Integrated bioinformatics and multi-omics reveal astragalus extract's gut-kidney axis mechanism in hyperuricemic nephropathy via purine metabolism

10.1016/j.phymed.2025.157121 · 2025 · External reference

GC-MS analysis of short-chain fatty acids in Feces, cecum content, and blood samples

10.1007/978-1-4939-7592-1_17 · 2018 · External reference

Effects and mechanisms of total flavones of Abelmoschus manihot in improving insulin resistance and podocyte epithelial-mesenchymal transition in diabetic kidney disease based on IRS1/PI3K/Akt pathway

10.19540/j.cnki.cjcmm.20221111.703 · 2023 · External reference

Apigenin protects against renal tubular epithelial cell injury and oxidative stress by high glucose via regulation of NF-E2-related factor 2 (Nrf2) pathway

10.12659/msm.915038 · 2019 · External reference

Protective effect of pueraria lobata flavonoids on the kidney in type 1 diabetic rats via the Nrf2/HO-1 signaling pathway

2021 · External reference

Icariin ameliorates streptozocin-induced diabetic nephropathy through suppressing the TLR4/NF-κB signal pathway

10.1039/d0fo02335c · 2021 · External reference

Protective effect and mechanism of apigenin on renal function in diabetic rats

2023 · External reference

Quercetin treats renal fibrosis in diabetic nephropathy via regulating P2X7R/NLRP3 pathway in mice

2023 · External reference

Effect of quercetin on tubular epithelial-mesenchymal transition in type 1 diabetic nephropathy

2022 · External reference

Quercetin ameliorates diabetic kidney injury by inhibiting ferroptosis via activating Nrf2/HO-1 signaling pathway

10.1142/s0192415x23500465 · 2023 · External reference

Vitexin ameliorated diabetic nephropathy via suppressing GPX4-mediated ferroptosis

10.1016/j.ejphar.2023.175787 · 2023 · External reference

Quercetin prevented diabetic nephropathy by inhibiting renal tubular epithelial cell apoptosis via the PI3K/Akt pathway

10.1002/ptr.8227 · 2024 · External reference

The effects of puerarin on autophagy through regulating of the PERK/eIF2α/ATF4 signaling pathway influences renal function in diabetic nephropathy

10.2147/dmso.s256457 · 2020 · External reference

Glycosides and flavonoids from the extract of Pueraria thomsonii Benth leaf alleviate type 2 diabetes in high-fat diet plus streptozotocin-induced mice by modulating the gut microbiota

10.1039/d1fo04170c · 2022 · External reference

Hyperuricemia is associated with impaired intestinal permeability in mice

10.1152/ajpgi.00151.2019 · 2019 · External reference

Strategies to reduce uric acid through gut microbiota intervention

10.3389/fmicb.2025.1654152 · 2025 · External reference

The gut microbiome in hyperuricemia and gout

10.1002/art.43118 · 2025 · External reference

Blockade of enhancer of zeste homolog 2 alleviates renal injury associated with hyperuricemia

10.1152/ajprenal.00234.2018 · 2019 · External reference

Short-chain fatty acids in diseases

10.1186/s12964-023-01219-9 · 2023 · External reference

The interplay between gut microbiota, short-chain fatty acids, and implications for host health and disease

10.1080/19490976.2024.2393270 · 2024 · External reference

Host-derived lactobacillus plantarum alleviates hyperuricemia by improving gut microbial community and hydrolase-mediated degradation of purine nucleosides

10.7554/elife.100068 · 2024 · External reference

Imperata cylindrica polysaccharide ameliorates intestinal dysbiosis and damage in hyperuricemic nephropathy

10.1016/j.ijbiomac.2024.134432 · 2024 · External reference

Effective extract of wild chrysanthemum modulates lipid emulsion gavage-induced hyperuricaemia model in rats via XOD/XDH pathway

2025 · External reference

Study on anti-trioxypurine effect and mechanism of dendrobium candidum simiao prescription on hyperuricemia rats

2019 · External reference

Electron transport chain inhibition increases cellular dependence on purine transport and salvage

10.1016/j.cmet.2024.05.014 · 2024 · External reference

Xanthine oxidoreductase inhibitors

10.1007/164_2020_383 · 2020 · External reference