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References from Paradoxical enhancement of oxidative stress-induced DNA damage and impaired redox homeostasis by Glutaredoxin 1 overexpression in human HeLa cells. Local targets link to admitted publications; unresolved targets remain external evidence.
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Targeted disruption of the glutaredoxin 1 gene does not sensitize adult mice to tissue injury induced by ischemia/reperfusion and hyperoxia
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1987 · External reference
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Deficiency of GRX1 leads to high sensitivity of HeLaS3 cells to oxidative stress via excessive accumulation of intracellular oxidants including ROS
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Glutaredoxin-1 silencing induces cell senescence via p53/p21/p16 signaling axis
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DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1
10.1038/sj.onc.1208875 · 2005 · External reference
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2008 · External reference
Constitutive histone H2AX phosphorylation and ATM activation, the reporters of DNA damage by endogenous oxidants
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ATM activates the pentose phosphate pathway promoting anti-oxidant defense and DNA repair
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The ataxia telangiectasia gene product is required for oxidative stress-induced G1 and G2 checkpoint function in human fibroblasts
10.1074/jbc.m011303200 · 2001 · External reference
Regulation of oxidative stress by ATM is required for self-renewal of hematopoietic stem cells
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p53R2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced DNA damage
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Glucose-6-phosphate dehydrogenase and the oxidative pentose phosphate cycle protect cells against apoptosis induced by low doses of ionizing radiation
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