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References from A MYCN–GAL–SREBP1 lipogenic axis drives proliferation in silent corticotroph adenomas. Local targets link to admitted publications; unresolved targets remain external evidence.
CBTRUS statistical report: American brain tumor association & NCI neuro-oncology branch adolescent and young adult primary brain and other central nervous system tumors diagnosed in the United States in 2016-2020
10.1093/neuonc/noae047 · 2024 · External reference
CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2017-2021
10.1093/neuonc/noae145 · 2024 · External reference
An update on silent corticotroph adenomas: diagnosis, mechanisms, clinical features, and management
10.3390/cancers13236134 · 2021 · External reference
The 2017 world health organization classification of tumors of the pituitary gland: a summary
10.1007/s00401-017-1769-8 · 2017 · External reference
Relevance of mutations in protein deubiquitinases genes and TP53 in corticotroph pituitary tumors
10.3389/fendo.2024.1302667 · 2024 · External reference
Recurrence in silent corticotroph adenomas after primary treatment: a systematic review and meta-analysis
10.1210/jc.2018-01956 · 2018 · External reference
Silent corticotroph adenomas
10.1007/s11102-018-0864-8 · 2018 · External reference
Treatment strategies and long-term outcomes in silent corticotroph adenomas: a single-center retrospective study of 367 cases
10.1227/neu.0000000000003142 · 2025 · External reference
Silent corticotroph adenomas after stereotactic radiosurgery: a case-control study
10.1016/j.ijrobp.2014.07.013 · 2014 · External reference
PCSK1N as a tumor size marker and an ER stress response protein in corticotroph pituitary adenomas
10.1210/clinem/dgae643 · 2025 · External reference
E-cadherin expression and gene expression profiles in corticotroph pituitary neuroendocrine tumor subtypes
10.1093/jnen/nlae034 · 2024 · External reference
Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity
10.1124/pr.112.006536 · 2015 · External reference
Coexpression of galanin and adrenocorticotropic hormone in human pituitary and pituitary adenomas
1991 · External reference
Galanin in human pituitary adenomas: frequency and clinical significance
10.1046/j.1365-2265.2002.01486.x · 2002 · External reference
Galanin suppresses proliferation of human U251 and T98G glioma cells via its subtype 1 receptor
10.1515/hsz-2016-0320 · 2017 · External reference
Galanin, neurotensin, and phorbol esters rapidly stimulate activation of mitogen-activated protein kinase in small cell lung cancer cells
1996 · External reference
Identification of galanin and its receptor GalR1 as novel determinants of resistance to chemotherapy and potential biomarkers in colorectal cancer
10.1158/1078-0432.ccr-12-1780 · 2012 · External reference
Transgenic mice over-expressing galanin exhibit pituitary adenomas and increased secretion of galanin, prolactin and growth hormone
10.1677/joe.0.1790145 · 2003 · External reference
Harnessing lipid metabolism modulation for improved immunotherapy outcomes in lung adenocarcinoma
10.1136/jitc-2024-008811 · 2024 · External reference
Lactate rewires lipid metabolism and sustains a metabolic-epigenetic axis in prostate cancer
10.1158/0008-5472.can-21-0914 · 2022 · External reference
The biology of cancer: metabolic reprogramming fuels cell growth and proliferation
10.1016/j.cmet.2007.10.002 · 2008 · External reference
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy
10.1126/scisignal.2000446 · 2009 · External reference
An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway
10.1158/2159-8290.cd-11-0102 · 2011 · External reference
Dysregulation of sterol response element-binding proteins and downstream effectors in prostate cancer during progression to androgen independence
10.1158/0008-5472.can-2148-2 · 2004 · External reference
UPLC-MS/MS-based lipidomic profiles revealed aberrant lipids associated with invasiveness of silent corticotroph adenoma
10.1210/clinem/dgaa708 · 2021 · External reference
Single-cell RNA sequencing in silent corticotroph tumors confirms impaired POMC processing and provides new insights into their invasive behavior
10.1530/eje-21-1183 · 2022 · External reference
Integrating single-cell transcriptomic data across different conditions, technologies, and species
10.1038/nbt.4096 · 2018 · External reference
Fast, sensitive and accurate integration of single-cell data with harmony
10.1038/s41592-019-0619-0 · 2019 · External reference
Dimensionality reduction for visualizing single-cell data using UMAP
10.1038/nbt.4314 · 2018 · External reference
Single-cell mRNA quantification and differential analysis with census
10.1038/nmeth.4150 · 2017 · External reference
The UCSC genome browser database: 2025 update
10.1093/nar/gkae974 · 2025 · External reference
JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
10.1093/nar/gkad1059 · 2024 · External reference
AlphaFold3: an overview of applications and performance insights
10.3390/ijms26083671 · 2025 · External reference
Single-cell transcriptomics reveal distinct immune-infiltrating phenotypes and macrophage-tumor interaction axes among different lineages of pituitary neuroendocrine tumors
10.1186/s13073-024-01325-4 · 2024 · External reference
Pangenomic classification of pituitary neuroendocrine tumors
10.1016/j.ccell.2019.11.002 · 2020 · External reference
The roles and mechanisms of SREBP1 in cancer development and drug response
10.1016/j.gendis.2023.04.022 · 2024 · External reference
Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma
10.1038/s41419-023-05738-8 · 2023 · External reference
Fatostatin suppresses growth and enhances apoptosis by blocking SREBP-regulated metabolic pathways in endometrial carcinoma
10.3892/or.2018.6265 · 2018 · External reference
Fatostatin displays high antitumor activity in prostate cancer by blocking SREBP-regulated metabolic pathways and androgen receptor signaling
10.1158/1535-7163.mct-13-0797 · 2014 · External reference
Neuroblastoma and MYCN
10.1101/cshperspect.a014415 · 2013 · External reference
MYC: connecting selective transcriptional control to global RNA production
10.1038/nrc3984 · 2015 · External reference
Role of MYCN in retinoblastoma: a review of current literature
10.1016/j.survophthal.2024.05.009 · 2024 · External reference
Computational and in vitro investigation of miRNA-gene regulations in retinoblastoma pathogenesis: miRNA mimics strategy
10.4137/bbi.s21742 · 2015 · External reference
The oncogene MYCN modulates glycolytic and invasive genes to enhance cell viability and migration in human retinoblastoma
10.3390/cancers13205248 · 2021 · External reference
