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References from The endeavor of total synthesis and its impact on chemistry, biology and medicine. Local targets link to admitted publications; unresolved targets remain external evidence.
The emergence of the structure of the molecule and the art of its synthesis
10.1002/anie.201207081 · 2013 · External reference
Unresolved reference
2011 · External reference
The art and science of total synthesis at the dawn of the twenty-first century
10.1002/(sici)1521-3773(20000103)39:1<44::aid-anie44>3.0.co;2-l · 2000 · External reference
Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance
10.1039/c2cs35116a · 2012 · External reference
Unresolved reference
1996 · External reference
Unresolved reference
2003 · External reference
Self-medication in animals
10.1126/science.1235824 · 2013 · External reference
Lessons from natural molecules
10.1038/nature03194 · 2004 · External reference
Unresolved reference
2008 · External reference
Ueber künstliche bildung des harnstoffs
10.1002/andp.18280880206 · 1828 · External reference
Beiträge zur kenntniss der gepaarten verbindungen.
10.1002/jlac.18450540202 · 1845 · External reference
Synthese des indigblaus
10.1002/cber.18780110206 · 1878 · External reference
Synthese des traubenzuckers
10.1002/cber.189002301126 · 1890 · External reference
The synthesis of monoterpenes
10.1002/9780470129654.ch1 · 1973 · External reference
Experiments on the synthesis of the terpenes: part I. Synthesis of terpin, inactive terpineol, and dipentene
10.1039/ct9048500654 · 1904 · External reference
A synthesis of tropinone
10.1039/ct9171100762 · 1917 · External reference
Synthese des hämatoporphyrins, protoporphyrins und hämins
10.1002/jlac.19294680104 · 1929 · External reference
The total synthesis of quinone
1944 · External reference
The total synthesis of strychnine
10.1021/ja01647a088 · 1954 · External reference
The synthesis of morphine
10.1021/ja01124a538 · 1952 · External reference
The total synthesis of penicillin V
10.1021/ja01562a063 · 1957 · External reference
Stereo-controlled synthesis of prostaglandins F2α and E2 (dl)
10.1021/ja01048a062 · 1969 · External reference
A novel synthesis of prostaglandin F2α
10.1021/ja00801a066 · 1973 · External reference
Acetylenic bond participation in biogenetic-like olefinic cyclizations. II. Synthesis of dl-progesterone
10.1021/ja00746a062 · 1971 · External reference
The total synthesis of vitamin B12
10.1351/pac197333010145 · 1973 · External reference
Synthetic studies on tetrodotoxin and related compounds. IV. Stereospecific total syntheses of DL-tetrodotoxin
10.1021/ja00781a039 · 1972 · External reference
Synthetic studies on polyether antibiotics. 6. Total synthesis of monensin. 3. Stereocontrolled total synthesis of monensin
10.1021/ja00495a066 · 1979 · External reference
Total synthesis of erythromycins. 4. Total synthesis of erythronolide B
10.1021/ja00482a063 · 1978 · External reference
The endiandric acid cascade. Electrocyclizations in organic synthesis. I. Stepwise, stereocontrolled total synthesis of endiandric acids A and B
10.1021/ja00384a077 · 1982 · External reference
The endiandric acid cascade. Electrocyclizations in organic synthesis. 2. Stepwise, stereocontrolled total synthesis of endiandric acids C–G
10.1021/ja00384a078 · 1982 · External reference
The endiandric acid cascade. Electrocyclizations in organic synthesis. 3. “Biomimetic” approach to endiandric acids A–G. Synthesis of precursors
10.1021/ja00384a079 · 1982 · External reference
The endiandric acid cascade. Electrocyclizations in organic synthesis. 4. Biomimetic approach to endiandric acids A–G. Total synthesis and thermal studies
10.1021/ja00384a080 · 1982 · External reference
Total synthesis of amphotericin B
10.1021/ja00243a043 · 1987 · External reference
Total synthesis of (±)-ginkgolide B
10.1021/ja00210a083 · 1988 · External reference
Total synthesis of rapamycin
10.1021/ja00063a093 · 1993 · External reference
Total synthesis of (–)-rapamycin using an Evans–Tischenko fragment coupling
10.1021/ja00070a058 · 1993 · External reference
Total synthesis of rapamycin via a novel titanium-mediated aldol macrocyclization reaction
10.1021/ja00073a083 · 1993 · External reference
Total synthesis of rapamycin and demethoxyrapamycin
10.1021/ja00124a043 · 1995 · External reference
Total synthesis of rapamycin
10.1002/anie.200604053 · 2007 · External reference
Enantioselective total synthesis of ecteinascidin 743
10.1021/ja962480t · 1996 · External reference
Total synthesis of ecteinascidin 743
10.1021/ja026216d · 2002 · External reference
Total synthesis of ecteinascidin 743
10.1021/ja0571794 · 2006 · External reference
Total synthesis of ecteinascidin 743
10.1021/ja408034x · 2013 · External reference
Stereospecific formal total synthesis of ecteinascidin 743
10.1002/anie.200503983 · 2006 · External reference
Synthetic studies on Et-743. Assembly of the pentacyclic core and a formal total synthesis
10.1021/jo801159k · 2008 · External reference
Synthetic studies toward ecteinascidin 743 (trabectedin)
10.1055/s-0032-1316579 · 2012 · External reference
Synthesis of palytoxin from palytoxin carboxylic acid
10.1021/ja00103a065 · 1994 · External reference
Total synthesis of halichondrin B and norhalichondrin B
10.1021/ja00034a086 · 1992 · External reference
Total synthesis of calicheamicin γ1I
10.1021/ja00051a063 · 1992 · External reference
A convergent total synthesis of calicheamicin γ1I
10.1002/anie.199408581 · 1994 · External reference
Total synthesis of (–)-epothilone A
10.1002/anie.199628011 · 1996 · External reference
Total synthesis of (–)-epothilone B: an extension of the Suzuki coupling method and insights into structure–activity relationships of the epothilones
10.1002/anie.199707571 · 1997 · External reference
Total synthesis of epothilone A: the olefin metathesis approach
10.1002/anie.199701661 · 1997 · External reference
Total synthesis of epothilone A: the macrolactonization approach
10.1002/anie.199705251 · 1997 · External reference
Total synthesis of (–)-epothilone A
10.1002/anie.199705231 · 1997 · External reference
Total synthesis of brevetoxin B. 1. CDEFG framework
10.1021/ja00108a051 · 1995 · External reference
Total synthesis of brevetoxin B. 2. Completion
10.1021/ja00108a052 · 1995 · External reference
Total synthesis of brevetoxin A
10.1038/32623 · 1998 · External reference
Total synthesis of brevetoxin A
10.1021/ol802710u · 2009 · External reference
Total synthesis of the CP molecules CP-225,917 and CP-263,114: part 2. Evolution of the final strategy
10.1002/(sici)1521-3773(19990601)38:11<1676::aid-anie1676>3.0.co;2-t · 1999 · External reference
Synthesis of (+)-CP-263,114
10.1021/ja001958x · 2000 · External reference
Total synthesis of (–)-CP-263,114 (phomoidride B)
10.1021/ja001664b · 2000 · External reference
The synthesis of CP-263,114 and CP-225,917: striking long-range stereocontrol in the fashioning of C7
10.1002/1521-3773(20001215)39:24<4509::aid-anie4509>3.0.co;2-f · 2000 · External reference
Total synthesis of vancomycin aglycon: part 3. Final stages
10.1002/(sici)1521-3773(19981016)37:19<2717::aid-anie2717>3.0.co;2-i · 1998 · External reference
Total synthesis of vancomycin
10.1002/(sici)1521-3773(19990115)38:1/2<240::aid-anie240>3.0.co;2-5 · 1999 · External reference
Total syntheses of vancomycin and eremomycin aglycons
10.1002/(sici)1521-3773(19981016)37:19<2700::aid-anie2700>3.0.co;2-p · 1998 · External reference
Diastereoselective total synthesis of the vancomycin aglycon with ordered atropisomer equilibrations
10.1021/ja990189i · 1999 · External reference
Total synthesis of everninomycin 13,384-1: part 1. Synthesis of the A1B(A)C fragment
10.1002/(sici)1521-3773(19991115)38:22<3334::aid-anie3334>3.0.co;2-h · 1999 · External reference
Total synthesis of everninomycin 13,384-1: part 2. Synthesis of the FGHA2 fragment
10.1002/(sici)1521-3773(19991115)38:22<3340::aid-anie3340>3.0.co;2-2 · 1999 · External reference
Total synthesis of everninomycin 13,384-1: part 3. Synthesis of the DE fragment and completion of the total synthesis
10.1002/(sici)1521-3773(19991115)38:22<3345::aid-anie3345>3.0.co;2-9 · 1999 · External reference
The first total synthesis of natural (–)-tetracycline
10.1246/cl.2000.646 · 2000 · External reference
Synthesis of (–)-tetracycline
10.1021/ja052151d · 2005 · External reference
Stereocontrolled total synthesis of (+)-vinblastine
10.1021/ja0177049 · 2002 · External reference
Direct coupling of catharanthine and vindoline to provide vinblastine: total synthesis of (+) and ent-(–)-vinblastine
10.1021/ja078192m · 2008 · External reference
Total synthesis of diazonamide A
10.1002/1521-3773(20020916)41:18<3495::aid-anie3495>3.0.co;2-7 · 2002 · External reference
The second total synthesis of diazonamide A
10.1002/anie.200351112 · 2003 · External reference
A concise and flexible total synthesis of (–)-diazonamide A
10.1002/anie.200352577 · 2003 · External reference
An expedient formal total synthesis of (–)-diazonamide A via a powerful, stereoselective O-aryl to C-aryl migration to form the C10 quaternary center
10.1021/ja0744448 · 2007 · External reference
A concise formal synthesis of diazonamide A by the stereoselective construction of the C10 quaternary center
10.1002/anie.200906318 · 2010 · External reference
Total synthesis of diazonamide A
10.1039/c0sc00577k · 2011 · External reference
Enantioselective total synthesis of quadrigemine C and psycholeine
10.1021/ja0267425 · 2002 · External reference
Structural revision and total synthesis of azaspiracid-1: part 1. Intelligence gathering and tentative proposal
10.1002/anie.200460695 · 2004 · External reference
Structural revision and total synthesis of azaspiracid-1: part 2. Definition of the ABCD domain and total synthesis
10.1002/anie.200460696 · 2004 · External reference
Total synthesis of (+)-azaspiracid-1: part I. Synthesis of the fully elaborated ABCD aldehyde
10.1002/anie.200701515 · 2007 · External reference
Total synthesis of (+)-azaspiracid-1: part II. Synthesis of the EFGHI sulfone and completion of the synthesis
10.1002/anie.200701520 · 2007 · External reference
Total synthesis of thiostrepton: part 1. Construction of the dehydropiperidine/thiazoline-containing macrocycle
10.1002/anie.200461340 · 2004 · External reference
Total synthesis of thiostrepton: part 2. Construction of the quinaldic acid macrocycle and final stages of the synthesis
10.1002/anie.200461341 · 2004 · External reference
The true structures of the vannusals: part 1. Initial forays into suspected structures and intelligence gathering
10.1002/anie.200902028 · 2009 · External reference
The true structures of the vannusals: part 2. Total synthesis and revised structure of vannusal B
10.1002/anie.200902029 · 2009 · External reference
Total synthesis and absolute configuration of the bisanthraquinone antibiotic BE-43472B
10.1002/anie.200900058 · 2009 · External reference
Total synthesis of the antibiotic BE-43472B
10.1002/anie.201301591 · 2013 · External reference
Total synthesis of (+)-haplophytine
10.1002/anie.200904588 · 2009 · External reference
Total synthesis of (+)-haplophytine
10.1002/anie.200902192 · 2009 · External reference
Total synthesis of vinigrol
10.1021/ja908194b · 2009 · External reference
A formal synthesis of vinigrol
10.1002/anie.201108779 · 2012 · External reference
Total synthesis of vinigrol
10.1002/anie.201304624 · 2013 · External reference
Total synthesis of a chlorosulpholipid cytotoxin associated with seafood poisoning
10.1038/nature07734 · 2009 · External reference
A synthesis of the chlorosulfolipid mytilipin A via a longest linear sequence of seven steps
10.1002/anie.201304565 · 2013 · External reference
Total synthesis of (+)-11,11’-dideoxyverticillin A
10.1126/science.1170777 · 2009 · External reference
Total synthesis of (+)-chaetocin and its analogues: their histone methyltransferase G9a inhibitory activity
10.1021/ja101280p · 2010 · External reference
Total synthesis of palau'amine
10.1002/anie.200907112 · 2010 · External reference
Total synthesis of (±) maoecrystal V
10.1021/ja108907x · 2010 · External reference
Total synthesis of (±)-maoecrystal V
10.1021/ja309905j · 2012 · External reference
Diastereoselective total synthesis of (±)-schindilactone A
10.1002/anie.201103088 · 2011 · External reference
A concise total synthesis of (–)-maoecrystal Z
10.1021/ja2073356 · 2011 · External reference
11-Step enantioselective synthesis of (–)-lomaiviticin aglycon
10.1021/ja200034b · 2011 · External reference
Total synthesis of (–)-fusarisetin A and reassignment of the absolute configuration of its natural counterpart
10.1021/ja211444m · 2012 · External reference
Nature-inspired total synthesis of (–)-fusarisetin A
10.1021/ja300807e · 2012 · External reference
Asymmetric total synthesis and biosynthetic implications of (+)-fusarisetin A
10.1002/anie.201202455 · 2012 · External reference
Asymmetric total synthesis of (+)-fusarisetin A via the intramolecular Pauson–Khand reaction
10.1021/ol401831w · 2013 · External reference
Component-based syntheses of trioxacarcin A, DC-45-A1 and structural analogues
10.1038/nchem.1746 · 2013 · External reference
Total synthesis of (–)-tirandamycin C
10.1021/ol203161u · 2012 · External reference
Enantioselective total synthesis of (–)-acetylaranotin, a dihydrooxepine epidithiodiketopiperazine
10.1021/ja209354e · 2012 · External reference
Total synthesis of (–)-acetylaranotin
10.1002/anie.201207307 · 2012 · External reference
Strategic redox relay enables a scalable synthesis of ouabagenin, a bioactive cardenolide
10.1126/science.1230631 · 2013 · External reference
Total synthesis and structural revision of viridicatumtoxin B
10.1002/anie.201304691 · 2013 · External reference
Endiandric acid, a novel carboxylic acid from Endiandra introrsa(Lauraceae): X-ray structure determination
10.1039/c39800000162 · 1980 · External reference
Postulated electrocyclic reactions leading to endiandric acid and related natural products
10.1039/c39800000902 · 1980 · External reference
Cascade reactions in total synthesis
10.1002/anie.200601872 · 2006 · External reference
p-Benzyne. Generation as an intermediate in a thermal isomerization reaction and trapping evidence for the 1, 4-benzenediyl structure
10.1021/ja00757a071 · 1972 · External reference
Calichemicins, a novel family of antitumor antibiotics: part 1. Chemistry and partial structure of calichemicin γ1I
10.1021/ja00245a050 · 1987 · External reference
Calichemicins, a novel family of antitumor antibiotics: part 2. Chemistry and structure of calichemicin γ1I
10.1021/ja00245a051 · 1987 · External reference
Chemistry and biology of the enediyne anticancer antibiotics
10.1002/anie.199113873 · 1991 · External reference
Chemistry and biology of natural and designed enediynes
10.1073/pnas.90.13.5881 · 1993 · External reference
The enediyne antibiotics
10.1021/jm9600398 · 1996 · External reference
Uncialamycin, a new enediyne antibiotic
10.1021/ol052081f · 2005 · External reference
Total synthesis and stereochemistry of uncialamycin
10.1002/anie.200700917 · 2007 · External reference
Asymmetric synthesis and biological properties of uncialamycin and 25-epi-uncialamycin
10.1002/anie.200704577 · 2007 · External reference
Plant antitumor agents. VI. Isolation and structure of Taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
10.1021/ja00738a045 · 1971 · External reference
Total synthesis of Taxol
10.1038/367630a0 · 1994 · External reference
First total synthesis of Taxol: part 1. Functionalization of the B ring
10.1021/ja00083a066 · 1994 · External reference
First total synthesis of Taxol: part 2. Completion of the C and D rings
10.1021/ja00083a067 · 1994 · External reference
A total synthesis of Taxol
10.1002/anie.199517231 · 1995 · External reference
The pinene path to taxanes: part 5. Stereocontrolled synthesis of a versatile taxane precursor
10.1021/ja9635387 · 1997 · External reference
The pinene path to taxanes: part 6. A concise stereocontrolled synthesis of Taxol
10.1021/ja963539z · 1997 · External reference
Asymmetric total synthesis of Taxol®
10.2183/pjab.73.95 · 1997 · External reference
Enantioselective total synthesis of Taxol
10.1021/ja9824932 · 1998 · External reference
A formal total synthesis of Taxol aided by an automated synthesizer
10.1002/asia.200600156 · 2006 · External reference
Isolation and structure of brevetoxin B from the “red tide” dinoflagellate Ptychodiscus brevis (Gymnodinium breve)
10.1021/ja00412a053 · 1981 · External reference
The total synthesis of brevetoxin B: a twelve-year odyssey in organic synthesis
10.1002/anie.199605881 · 1996 · External reference
Total synthesis of brevetoxin-B
10.1021/ja0449269 · 2004 · External reference
Total synthesis of brevetoxin B
10.1021/ja051171c · 2005 · External reference
The continuing saga of the marine polyether biotoxins
10.1002/anie.200801696 · 2008 · External reference
Maitotoxin: an inspiration for synthesis
10.1002/ijch.201100003 · 2011 · External reference
Vancomycin, a new antibiotic: part I. Chemical and biologic properties
External reference
Target-accelerated combinatorial synthesis and discovery of highly potent antibiotics effective against vancomycin-resistant bacteria
10.1002/1521-3773(20001103)39:21<3823::aid-anie3823>3.0.co;2-3 · 2000 · External reference
New synthetic technology for the synthesis of aryl ethers: construction of C-O-D and D-O-E ring model systems of vancomycin
10.1021/ja9636350 · 1997 · External reference
New selenium-based safety-catch linkers: solid-phase semisynthesis of vancomycin
10.1002/(sici)1521-3773(20000317)39:6<1084::aid-anie1084>3.0.co;2-o · 2000 · External reference
CP-225,917 and CP-263,114, novel ras farnesylation inhibitors from an unidentified fungus
10.7164/antibiotics.50.1 · 1997 · External reference
CP-225,917 and CP-263,114, novel ras farnesylation inhibitors from an unidentified fungus. 2. Structure elucidation
10.1021/ja961000v · 1997 · External reference
The CP molecule labyrinth: a paradigm of how endeavors in total synthesis lead to discoveries and invention in organic synthesis
10.1002/1521-3773(20020802)41:15<2678::aid-anie2678>3.0.co;2-v · 2002 · External reference
A novel route to the fused maleic anhydride moiety of CP molecules
10.1002/(sici)1521-3773(19990215)38:4<549::aid-anie549>3.0.co;2-o · 1999 · External reference
Novel strategies to construct the γ-hydroxy lactone moiety of the CP molecules. Synthesis of the CP-225,917 core skeleton
10.1021/ol990551y · 1999 · External reference
New synthetic technology for the rapid construction of novel heterocycles: part 1. The reaction of Dess–Martin periodinane with anilides and related compounds
10.1002/(sici)1521-3773(20000204)39:3<622::aid-anie622>3.0.co;2-b · 2000 · External reference
New synthetic technology for the rapid construction of novel heterocycles: part 2. The reaction of IBX with anilides and related compounds
10.1002/(sici)1521-3773(20000204)39:3<625::aid-anie625>3.0.co;2-# · 2000 · External reference
A new method for the one-step synthesis of α,β-unsaturated carbonyl systems from saturated alcohols and carbonyl compounds
10.1021/ja001825b · 2000 · External reference
Selective oxidation at carbon adjacent to aromatic systems with IBX
10.1021/ja004218x · 2001 · External reference
o-Iodoxybenzoic acid (IBX) as a viable reagent in the manipulation of nitrogen- and sulfur-containing substrates: scope, generality, and mechanism of IBX-mediated amine oxidations and dithiane deprotections
10.1021/ja0400382 · 2004 · External reference
New synthetic technology for the synthesis of hindered α-diazoketones via acyl mesylates
10.1021/ol990790l · 1999 · External reference
New synthetic technology for the mild and selective one-carbon homologation of hindered aldehydes in the presence of ketones
10.1021/ol000102u · 2000 · External reference
Azaspiracid, a new marine toxin having unique spiro ring assemblies, isolated from Irish mussels, Mytilus edulis
10.1021/ja981413r · 1998 · External reference
Total synthesis of the proposed azaspiracid-1 structure: part 1. Construction of the enantiomerically pure C1–C20, C21–C27, and C28–C40 fragments
10.1002/anie.200351825 · 2003 · External reference
Total synthesis of the proposed azaspiracid-1 structure: part 2. Coupling of the C1–C20, C21–C27, and C28–C40 fragments and completion of the synthesis
10.1002/anie.200351826 · 2003 · External reference
Irreversible cytoskeletal disarrangement is independent of caspase activation during in vitro azaspiracid toxicity in human neuroblastoma cells
10.1016/j.bcp.2007.04.004 · 2007 · External reference
Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3
10.1002/anie.200600295 · 2006 · External reference
Second-generation total synthesis of azaspiracids-1, -2, and -3
10.1002/asia.200600059 · 2006 · External reference
Thiostrepton, a new antibiotic. I. In vitro studies
External reference
Thiostrepton, a new antibiotic. II. Isolation and chemical characterization
External reference
Thiostrepton, a new antibiotic. III. In vivo studies
External reference
How thiostrepton was made in the laboratory
10.1002/anie.201205576 · 2012 · External reference
From amino acids to heteroaromatics—thiopeptide antibiotics, nature's heterocyclic peptides
10.1002/anie.200700728 · 2007 · External reference
Total synthesis of antibiotics GE2270A and GE2270T
10.1002/anie.200602798 · 2006 · External reference
Total synthesis of thiopeptide antibiotics GE2270A, GE2270T, and GE2270C1
10.1002/asia.200700361 · 2008 · External reference
Total syntheses of amythiamicins A, B, and C
10.1039/b805069b · 2008 · External reference
Sporolides A and B: structurally unprecedented halogenated macrolides from the marine actinomycete salinispora tropica
10.1021/ol050901i · 2005 · External reference
Genome sequencing reveals complex secondary metabolome in the marine actinomycete salinispora tropica
10.1073/pnas.0700962104 · 2007 · External reference
Total synthesis of sporolide B
10.1002/anie.200900264 · 2009 · External reference
2,5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural products
10.1021/cr200398y · 2012 · External reference
Total synthesis of epicoccin G
10.1021/ja2032635 · 2011 · External reference
Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8′-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimalarial agents
10.1021/ja308429f · 2012 · External reference
SYP. A practical sulfenylation of 2,5-diketopiperazines
10.1002/anie.201107623 · 2012 · External reference
Viridicatumtoxin B, a new anti-MRSA agent from penicillium sp FR11
10.1038/ja.2008.84 · 2008 · External reference
