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References from Causal Relationship of Polyunsaturated Fatty Acids With Mental Disorders: A Systematic Review and Meta-analysis. Local targets link to admitted publications; unresolved targets remain external evidence.
What is a mental disorder? An exemplar-focused approach
10.1017/s0033291721001185 · 2021 · External reference
Age of onset and cumulative risk of mental disorders: a cross-national analysis of population surveys from 29 countries
10.1016/s2215-0366(23)00193-1 · 2023 · External reference
Antidepressant and antipsychotic side-effects and personalised prescribing: a systematic review and digital tool development
10.1016/s2215-0366(23)00262-6 · 2023 · External reference
Treatment considerations in severe mental illness: caring for the whole patient
10.1001/jamapsychiatry.2019.0903 · 2019 · External reference
Treatment rates for mental disorders among children and adolescents: a systematic review and meta-analysis
10.1001/jamanetworkopen.2023.38174 · 2023 · External reference
Food and mood: how do diet and nutrition affect mental wellbeing?
10.1136/bmj.m2382 · 2020 · External reference
Effectiveness of nutrition and dietary interventions for people with serious mental illness: systematic review and meta-analysis
2022 · External reference
Diet-derived fatty acids, brain inflammation, and mental health
10.3389/fnins.2019.00265 · 2019 · External reference
Dietary lipids from body to brain
10.1016/j.plipres.2021.101144 · 2022 · External reference
Polyunsaturated fatty acids and their metabolites in brain function and disease
10.1038/nrn3820 · 2014 · External reference
Efficacy of polyunsaturated fatty acids (PUFAs) on impulsive behaviours and aggressiveness in psychiatric disorders
10.3390/ijms22020620 · 2021 · External reference
Mendelian randomization as an approach to assess causality using observational data
10.1681/asn.2016010098 · 2016 · External reference
Omega-3 polyunsaturated fatty acids in youths with attention deficit hyperactivity disorder: a systematic review and meta-analysis of clinical trials and biological studies
10.1038/npp.2017.160 · 2018 · External reference
Omega-3 polyunsaturated fatty acid supplementation and cognition: a systematic review and meta-analysis
10.1177/0269881115587958 · 2015 · External reference
N-3 polyunsaturated fatty acids in elderly with mild cognitive impairment: a systemic review and meta-analysis
10.3233/jad-220863 · 2024 · External reference
Polyunsaturated fatty acids and risk of Alzheimer’s disease: a Mendelian randomization study
10.1007/s00394-019-02126-x · 2020 · External reference
Unsaturated fatty acids in mental disorders: an umbrella review of meta-analyses
10.1093/advances/nmac084 · 2022 · External reference
Metabolomic investigation of major depressive disorder identifies a potentially causal association with polyunsaturated fatty acids
10.1016/j.biopsych.2023.01.027 · 2023 · External reference
A role for vitamin D and omega-3 fatty acids in major depression? An exploration using genomics
10.1038/s41398-019-0554-y · 2019 · External reference
Meta-analysis and Mendelian randomization: a review
10.1002/jrsm.1346 · 2019 · External reference
The PRISMA 2020 statement: an updated guideline for reporting systematic reviews
10.1136/bmj.n71 · 2021 · External reference
Mendelian randomization studies on coronary artery disease: a systematic review and meta-analysis
10.1186/s13643-023-02442-8 · 2024 · External reference
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10.1146/annurev-psych-010418-102803 · 2019 · External reference
Causal role of high body mass index in multiple chronic diseases: a systematic review and meta-analysis of Mendelian randomization studies
10.1186/s12916-021-02188-x · 2021 · External reference
Omega-3 fatty acids and major depression: a Mendelian randomization study
10.1038/s41398-024-02932-w · 2024 · External reference
Circulating metabolite abundances associated with risks of bipolar disorder, schizophrenia, and depression: a Mendelian randomization study
10.1016/j.biopsych.2024.04.016 · 2024 · External reference
Assessment of causal relationships between omega-3 and omega-6 polyunsaturated fatty acids in bipolar disorder: a 2-sample bidirectional Mendelian randomization study
10.1039/d3fo00265a · 2023 · External reference
Mendelian randomization of the causal relationship between omega-3 polyunsaturated fatty acids and major depression]
2023 · External reference
Mendelian randomization found no causal relationship between omega-6 fatty acids and attention deficit hyperactivity disorder (ADHD)
10.21037/amj-22-74 · 2023 · External reference
Causal effects of fatty acids on depression: Mendelian randomization study
10.3389/fnut.2022.1010476 · 2022 · External reference
Associations of genetically predicted fatty acid levels across the phenome: a Mendelian randomisation study
10.1371/journal.pmed.1004141 · 2022 · External reference
Disentangling independent and mediated causal relationships between blood metabolites, cognitive factors, and Alzheimer’s disease
10.1016/j.bpsgos.2021.07.010 · 2022 · External reference
Omega-3 fatty acids and major depression: a Mendelian randomization study
10.1038/s41398-024-02932-w · 2024 · External reference
Importance of EPA and DHA blood levels in brain structure and function
10.3390/nu13041074 · 2021 · External reference
Non-pharmacological interventions for attention-deficit hyperactivity disorder in children and adolescents
10.1016/s2352-4642(22)00381-9 · 2023 · External reference
Nutritional interventions for autism spectrum disorder
10.1093/nutrit/nuz092 · 2020 · External reference
Polyunsaturated fatty acids and recurrent mood disorders: phenomenology, mechanisms, and clinical application
10.1016/j.plipres.2017.01.001 · 2017 · External reference
Omega-3 polyunsaturated fatty acids protect against inflammation through production of LOX and CYP450 lipid mediators: relevance for major depression and for human hippocampal neurogenesis
10.1038/s41380-021-01160-8 · 2021 · External reference
Lack of evidence for efficacy of omega-3 fatty acids in depression
10.1111/acps.13357 · 2021 · External reference
A pilot randomized controlled trial testing supplements of omega-3 fatty acids, probiotics, combination or placebo on symptoms of depression, anxiety and stress
2021 · External reference
Possible antidepressant mechanisms of omega-3 polyunsaturated fatty acids acting on the central nervous system
10.3389/fpsyt.2022.933704 · 2022 · External reference
Effects of long-chain omega-3 polyunsaturated fatty acids on reducing anxiety and/or depression in adults: a systematic review and meta-analysis of randomised controlled trials
10.1016/j.plefa.2023.102572 · 2023 · External reference
Marine omega-3 fatty acid supplementation for borderline personality disorder: a meta-analysis
10.4088/jcp.20r13613 · 2021 · External reference
Relevance of omega-6 GLA added to omega-3 PUFAs supplements for ADHD: a narrative review
10.3390/nu14163273 · 2022 · External reference
Omega-6 to omega-3 polyunsaturated fatty acid ratio and subsequent mood disorders in young people with at-risk mental states: a 7-year longitudinal study
10.1038/tp.2017.190 · 2017 · External reference
Omega-3 polyunsaturated fatty acid levels and dysregulations in biological stress systems
10.1016/j.psyneuen.2018.07.002 · 2018 · External reference
Nutritional omega-3 deficiency alters glucocorticoid receptor-signaling pathway and neuronal morphology in regionally distinct brain structures associated with emotional deficits
10.1155/2016/8574830 · 2016 · External reference
The role of omega-3 polyunsaturated fatty acids eicosapentaenoic and docosahexaenoic acids in the treatment of major depression and Alzheimer’s disease: acting separately or synergistically?
10.1016/j.plipres.2015.12.003 · 2016 · External reference
Intake and metabolism of omega-3 and omega-6 polyunsaturated fatty acids: nutritional implications for cardiometabolic diseases
10.1016/s2213-8587(20)30148-0 · 2020 · External reference
CRHR1 antagonist alleviated depression-like behavior by downregulating p62 in a rat model of post-stroke depression
10.1016/j.expneurol.2024.114822 · 2024 · External reference
HPA axis in the pathomechanism of depression and schizophrenia: new therapeutic strategies based on its participation
10.3390/brainsci11101298 · 2021 · External reference
The effects and mechanisms of n-3 and n-6 polyunsaturated fatty acids in the central nervous system
10.1007/s10571-025-01543-3 · 2025 · External reference
Gut microbiota and neuropsychiatric disorders: implications for neuroendocrine-immune regulation
10.1016/j.phrs.2021.105909 · 2021 · External reference
The importance of marine omega-3s for brain development and the prevention and treatment of behavior, mood, and other brain disorders
10.3390/nu12082333 · 2020 · External reference
Omega-3 polyunsaturated fatty acids suppress the inflammatory responses of lipopolysaccharide-stimulated mouse microglia by activating SIRT1 pathways
10.1016/j.bbalip.2017.02.010 · 2017 · External reference
Protective effect of alpha-linoleic acid on Abeta-induced oxidative stress, neuroinflammation, and memory impairment by alteration of alpha7 nAChR and NMDAR gene expression in the hippocampus of rats
10.1016/j.neuro.2021.06.002 · 2021 · External reference
Omega-3 and folic acid act against depressive-like behavior and oxidative damage in the brain of rats subjected to early- or late-life stress
10.1016/j.nut.2018.03.006 · 2018 · External reference
Infrared image construction with computer-generated reflection holograms
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n-3 Fatty acids: role in neurogenesis and neuroplasticity
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Depression and adult neurogenesis: positive effects of the antidepressant fluoxetine and of physical exercise
10.1016/j.brainresbull.2018.09.002 · 2018 · External reference
Modulation of neuroinflammation and oxidative stress by targeting GPR55—new approaches in the treatment of psychiatric disorders
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