Research graph
References from Chlorogenic Acid–Gut Microbiota Interactions: New Insights for Alleviating Chronic Diseases and Health Disorders. Local targets link to admitted publications; unresolved targets remain external evidence.
Chlorogenic acids: a pharmacological systematic review on their hepatoprotective effects
10.1016/j.phymed.2023.154961 · 2023 · External reference
Chlorogenic acid: a dietary phenolic acid with promising pharmacotherapeutic potential
10.2174/0929867329666220816154634 · 2023 · External reference
Chlorogenic acid derivatives: structural modifications, drug design, and biological activities: a review
10.2174/1389557523666230822095959 · 2024 · External reference
Chlorogenic acid ameliorates post-infectious irritable bowel syndrome by regulating extracellular vesicles of gut microbes
10.1002/advs.202302798 · 2023 · External reference
Moderation of gut microbiota and bile acid metabolism by chlorogenic acid improves high-fructose-induced salt-sensitive hypertension in mice
10.1039/d2fo00038e · 2022 · External reference
Feeding gut microbes to nourish the brain: unravelling the diet-microbiota-gut-brain axis
10.1038/s42255-024-01108-6 · 2024 · External reference
Chlorogenic acid inhibits trimethylamine-N-oxide formation and remodels intestinal microbiota to alleviate liver dysfunction in high L-carnitine feeding mice
10.1039/d1fo01778k · 2021 · External reference
Chlorogenic acid/linoleic acid-fortified wheat-resistant starch ameliorates high-fat diet-induced gut barrier damage by modulating gut metabolism
10.1021/acs.jafc.4c01595 · 2024 · External reference
Nutritional assessment in patients with chronic diseases: tools, challenges, and future directions
10.3390/nu15224794 · 2023 · External reference
Fast, sensitive, and sustainable colorimetric detection of chlorogenic acid in artichoke waste material
10.1016/j.foodchem.2024.141505 · 2025 · External reference
Chlorogenic acids and the acyl-quinic acids: discovery, biosynthesis, bioavailability and bioactivity
10.1039/c7np00030h · 2017 · External reference
Chlorogenic acid: a comprehensive review of the dietary sources, processing effects, bioavailability, beneficial properties, mechanisms of action, and future directions
10.1111/1541-4337.12620 · 2020 · External reference
Coffee bean and its chemical constituent caffeine and chlorogenic acid as promising chemoprevention agents: updated biological studies against cancer cells
10.3390/molecules29143302 · 2024 · External reference
Glutathionyl-S-chlorogenic acid is present in fruit of Vaccinium species, potato tubers and apple juice
10.1016/j.foodchem.2020.127227 · 2020 · External reference
Quantitative determination of phenolic compounds in artichoke-based dietary supplements and pharmaceuticals by high-performance liquid chromatography
10.1021/jf062009b · 2006 · External reference
Simultaneous separation and determination of five chlorogenic acid isomers in honeysuckle by capillary electrophoresis using self-synthesized ionic liquid [N-methylimidazole-β-cyclodextrin] [bromide] as separation selector
10.1002/jssc.202200352 · 2022 · External reference
Activity and concentration of polyphenolic antioxidants in apple juice. 2. Effect of novel production methods
10.1021/jf0306800 · 2004 · External reference
Microencapsulation by spray-drying and freeze-drying of extract of phenolic compounds obtained from Ciriguela peel
10.1038/s41598-023-40390-4 · 2023 · External reference
Bioavailability and metabolism of chlorogenic acids (acyl-quinic acids) in humans
10.1111/1541-4337.12518 · 2020 · External reference
Caffeoylquinic acids: chemistry, biosynthesis, occurrence, analytical challenges, and bioactivity
10.1111/tpj.15390 · 2021 · External reference
Chlorogenic acid is absorbed in its intact form in the stomach of rats
10.1093/jn/136.5.1192 · 2006 · External reference
Current advances in naturally occurring caffeoylquinic acids: structure, bioactivity, and synthesis
10.1021/acs.jafc.0c03804 · 2020 · External reference
Optimization of ultrasonic pretreatment and analysis of chlorogenic acid in potato leaves
10.1038/s41598-024-61139-7 · 2024 · External reference
Bioavailability of coffee chlorogenic acids and green tea flavan-3-ols
10.3390/nu2080820 · 2010 · External reference
Bioavailability of chlorogenic acids in rats after acute ingestion of maté tea (Ilex paraguariensis) or 5-caffeoylquinic acid
10.1007/s00394-016-1290-1 · 2017 · External reference
Absorption and metabolism of caffeic acid and chlorogenic acid in the small intestine of rats
10.1079/bjn20061714 · 2006 · External reference
Absorption of chlorogenic acid and caffeic acid in rats after oral administration
10.1021/jf000483q · 2000 · External reference
Enzymatic mitigation of 5-O-chlorogenic acid for an improved digestibility of coffee
10.1016/j.foodchem.2018.03.061 · 2018 · External reference
Chlorogenic acid compounds from coffee are differentially absorbed and metabolized in humans
10.1093/jn/137.10.2196 · 2007 · External reference
Chlorogenic acid and quercetin in a diet with fermentable fiber influence multiple processes involved in DSS-induced ulcerative colitis but do not reduce injury
10.3390/nu14183706 · 2022 · External reference
Coffee chlorogenic acids incorporation for bioactivity enhancement of foods: a review
10.3390/molecules27113400 · 2022 · External reference
An insight into gut microbiota and its functionalities
10.1007/s00018-018-2943-4 · 2019 · External reference
Gut Bacteroides species in health and disease
10.1080/19490976.2020.1848158 · 2021 · External reference
Gut bacteria: an etiological agent in human pathological conditions
10.3389/fcimb.2024.1291148 · 2024 · External reference
(Dis)Trust your gut: the gut microbiome in age-related inflammation, health, and disease
10.1186/s40168-017-0296-0 · 2017 · External reference
Dietary chlorogenic acid regulates gut microbiota, serum-free amino acids and colonic serotonin levels in growing pigs
10.1080/09637486.2017.1394449 · 2018 · External reference
In vitro transformation of chlorogenic acid by human gut microbiota
10.1002/mnfr.201300441 · 2014 · External reference
Microbial metabolism of caffeic acid and its esters chlorogenic and caftaric acids by human faecal microbiota in vitro
10.1016/j.biopha.2006.07.084 · 2006 · External reference
Chlorogenic acid versus amaranth’s caffeoylisocitric acid—gut microbial degradation of caffeic acid derivatives
10.1016/j.foodres.2017.06.013 · 2017 · External reference
Apple polyphenol extract modulates bile acid metabolism and gut microbiota by regulating the circadian rhythms in daytime-restricted high fat diet feeding C57BL/6 male mice
10.1039/d1fo04116a · 2022 · External reference
In vitro colonic metabolism of coffee and chlorogenic acid results in selective changes in human faecal microbiota growth
10.1017/s0007114514003948 · 2015 · External reference
Caffeic acid and its derivatives: antimicrobial drugs toward microbial pathogens
10.1021/acs.jafc.0c07579 · 2021 · External reference
Caffeic acid supplement alleviates colonic inflammation and oxidative stress potentially through improved gut microbiota community in mice
10.3389/fmicb.2021.784211 · 2021 · External reference
Caffeic acid prevents non-alcoholic fatty liver disease induced by a high-fat diet through gut microbiota modulation in mice
10.1016/j.foodres.2021.110240 · 2021 · External reference
Novel tricyclic-alpha-alkyloxyphenylpropionic acids: dual PPARalpha/gamma agonists with hypolipidemic and antidiabetic activity
10.1021/jm010964g · 2002 · External reference
Resveratrol reduces obesity in high-fat diet-fed mice via modulating the composition and metabolic function of the gut microbiota
10.1016/j.freeradbiomed.2020.04.013 · 2020 · External reference
Osteogenic mechanism of chlorogenic acid and its application in clinical practice
10.3389/fphar.2024.1396354 · 2024 · External reference
In vitro gut metabolism of [U-13 C]-quinic acid, the other hydrolysis product of chlorogenic acid
10.1002/mnfr.201800396 · 2018 · External reference
The gut microbiome drives inter- and intra-individual differences in metabolism of bioactive small molecules
10.1038/s41598-020-76558-5 · 2020 · External reference
Changes of porcine gut microbiota in response to dietary chlorogenic acid supplementation
10.1007/s00253-019-10025-8 · 2019 · External reference
Grafting chlorogenic acid enhanced the antioxidant activity of curdlan oligosaccharides and modulated gut microbiota
10.1016/j.fochx.2023.101075 · 2024 · External reference
Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.)
10.3389/fmicb.2022.977292 · 2022 · External reference
Effects of dietary chlorogenic acid on ileal intestinal morphology, barrier function, immune factors and gut microbiota of broilers under high stocking density stress
10.3389/fphys.2023.1169375 · 2023 · External reference
Effects of dietary chlorogenic acid on cecal microbiota and metabolites in broilers during lipopolysaccharide-induced immune stress
10.3389/fmicb.2024.1347053 · 2024 · External reference
Dietary supplementation with chlorogenic acid enhances antioxidant capacity, which promotes growth, jejunum barrier function, and cecum microbiota in broilers under high stocking density stress
10.3390/ani13020303 · 2023 · External reference
Responses of intestinal antioxidant capacity, morphology, barrier function, immunity, and microbial diversity to chlorogenic acid in late-peak laying hens
10.3390/ani14202957 · 2024 · External reference
Global incidence and prevalence of nonalcoholic fatty liver disease
10.3350/cmh.2022.0365 · 2023 · External reference
Polyphenols improve non-alcoholic fatty liver disease via gut microbiota: a comprehensive review
10.1002/fsn3.4178 · 2024 · External reference
Amelioration of non-alcoholic steatohepatitis by Atractylodes macrocephala polysaccharide, chlorogenic acid, and geniposide combination is associated with reducing endotoxin gut leakage
10.3389/fcimb.2022.827516 · 2022 · External reference
Chlorogenic acid alleviated liver fibrosis in methionine and choline deficient diet-induced nonalcoholic steatohepatitis in mice and its mechanism
10.1016/j.jnutbio.2022.109020 · 2022 · External reference
The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota
10.1002/hep.28356 · 2016 · External reference
Chlorogenic acid improves NAFLD by regulating gut microbiota and GLP-1
10.3389/fphar.2021.693048 · 2021 · External reference
Apple polyphenol extract improves high-fat diet-induced hepatic steatosis by regulating bile acid synthesis and gut microbiota in C57BL/6 male mice
10.1021/acs.jafc.1c02532 · 2021 · External reference
Geniposide and chlorogenic acid combination ameliorates non-alcoholic steatohepatitis involving the protection on the gut barrier function in mouse induced by high-fat diet
10.3389/fphar.2018.01399 · 2018 · External reference
Short term effects of coffee components consumption on gut microbiota in patients with non-alcoholic fatty liver and diabetes: a pilot randomized placebo-controlled, clinical trial
2020 · External reference
Indole-3-carbinol and chlorogenic acid combination modulates gut microbiome and attenuates nonalcoholic steatohepatitis in a murine model
10.1016/j.foodres.2023.113513 · 2023 · External reference
Effects of dicaffeoylquinic acids from ilex kudingcha on lipid metabolism and intestinal microbiota in high-fat-diet-fed mice
10.1021/acs.jafc.8b05444 · 2019 · External reference
Interaction between phenolics and gut microbiota: role in human health
10.1021/jf902107d · 2009 · External reference
Dietary chlorogenic acid alleviates high-fat diet-induced steatotic liver disease by regulating metabolites and gut microbiota
10.1080/09637486.2024.2318590 · 2024 · External reference
Contemporary medical, device, and surgical therapies for obesity in adults
10.1016/s0140-6736(22)02403-5 · 2023 · External reference
Chlorogenic acid alleviates obesity and modulates gut microbiota in high-fat-fed mice
10.1002/fsn3.868 · 2019 · External reference
Chlorogenic acid improves anti-lipogenic activity of metformin by positive regulating of AMPK signaling in HepG2 cells
10.1007/s12013-022-01077-1 · 2022 · External reference
Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice
10.1016/j.fct.2010.01.003 · 2010 · External reference
Chlorogenic acid ameliorates obesity by preventing energy balance shift in high-fat diet induced obese mice
10.1002/jsfa.10675 · 2021 · External reference
Chlorogenic acid-induced gut microbiota improves metabolic endotoxemia
10.3389/fendo.2021.762691 · 2021 · External reference
Chlorogenic acid in green bean coffee on body weight: a systematic review and meta-analysis of randomized controlled trials
10.1186/s13643-023-02311-4 · 2023 · External reference
Gut microbiota and predicted metabolic pathways in a sample of Mexican women affected by obesity and obesity plus metabolic syndrome
10.3390/ijms20020438 · 2019 · External reference
Alteration of the gut microbiota associated with childhood obesity by 16S rRNA gene sequencing
10.7717/peerj.8317 · 2020 · External reference
The gut microbiome of Mexican children affected by obesity
10.1016/j.anaerobe.2018.10.009 · 2019 · External reference
The gut microbiota and its relationship to diet and obesity: new insights
10.4161/gmic.20168 · 2012 · External reference
Obesity influences the microbiotic biotransformation of chlorogenic acid
10.1016/j.jpba.2021.114550 · 2022 · External reference
High phenolics Rutgers Scarlet Lettuce improves glucose metabolism in high fat diet-induced obese mice
10.1002/mnfr.201600290 · 2016 · External reference
Effects of baicalin and chlorogenic acid on growth performance, slaughter performance, antioxidant capacity, immune function and intestinal health of broilers
10.1016/j.psj.2024.104251 · 2024 · External reference
Chlorogenic acid protects against indomethacin-induced inflammation and mucosa damage by decreasing Bacteroides-derived LPS
10.3389/fimmu.2020.01125 · 2020 · External reference
Polyphenol-rich diet mediates interplay between macrophage-neutrophil and gut microbiota to alleviate intestinal inflammation
10.1038/s41419-023-06190-4 · 2023 · External reference
Chlorogenic acid ameliorates intestinal inflammation via miRNA-microbe axis in db/db mice
10.1096/fj.202400382r · 2024 · External reference
Chlorogenic acid ameliorates experimental colitis by promoting growth of Akkermansia in mice
10.3390/nu9070677 · 2017 · External reference
Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice
10.1039/d2fo03306b · 2023 · External reference
Dietary chlorogenic acid supplementation affects gut morphology, antioxidant capacity and intestinal selected bacterial populations in weaned piglets
10.1039/c8fo01126e · 2018 · External reference
Chlorogenic acid enhances the intestinal health of weaned piglets by inhibiting the TLR4/NF-κB pathway and activating the Nrf2 pathway
10.3390/ijms25189954 · 2024 · External reference
An update on chronic complications of diabetes mellitus: from molecular mechanisms to therapeutic strategies with a focus on metabolic memory
10.1186/s10020-024-00824-9 · 2024 · External reference
Myofibrillar protein-chlorogenic acid complexes ameliorate glucose metabolism via modulating gut microbiota in a type 2 diabetic rat model
10.1016/j.foodchem.2022.135195 · 2023 · External reference
Chlorogenic acid improves glucose tolerance, lipid metabolism, inflammation and microbiota composition in diabetic db/db mice
10.3389/fendo.2022.1042044 · 2022 · External reference
Kidney aging and chronic kidney disease
10.3390/ijms25126585 · 2024 · External reference
Chlorogenic acid prevents hyperuricemia nephropathy via regulating TMAO-related gut microbes and inhibiting the PI3K/AKT/mTOR pathway
10.1021/acs.jafc.2c03099 · 2022 · External reference
Chlorogenic acid relieves lead-induced cognitive impairments and hepato-renal damage via regulating the dysbiosis of the gut microbiota in mice
10.1039/c8fo01755g · 2019 · External reference
Chlorogenic acid supplementation ameliorates hyperuricemia, relieves renal inflammation, and modulates intestinal homeostasis
10.1039/d0fo03199b · 2021 · External reference
Protection mechanisms underlying oral administration of chlorogenic acid against cadmium-induced hepatorenal injury related to regulating intestinal flora balance
10.1021/acs.jafc.0c06698 · 2021 · External reference
Diet, inflammation and the gut microbiome: mechanisms for obesity-associated cognitive impairment
10.1016/j.bbadis.2020.165767 · 2020 · External reference
Polyphenols and neuroprotection: therapeutic implications for cognitive decline
10.1016/j.pharmthera.2021.108013 · 2022 · External reference
Chlorogenic acid ameliorates high-fat and high-fructose diet-induced cognitive impairment via mediating the microbiota-gut-brain axis
10.1021/acs.jafc.1c07479 · 2022 · External reference
Gut microbiota in combination with blood metabolites reveals characteristics of the disease cluster of coronary artery disease and cognitive impairment: a Mendelian randomization study
10.3389/fimmu.2023.1308002 · 2023 · External reference
Chlorogenic acid improves the cognitive deficits of sleep-deprived mice via regulation of immunity function and intestinal flora
10.1016/j.phymed.2023.155194 · 2024 · External reference
Protective effects of chlorogenic acid on trimethyltin chloride-induced neurobehavioral dysfunctions in mice relying on the gut microbiota
10.1039/d1fo03334d · 2022 · External reference
A flower-like brain targeted selenium nanocluster lowers the chlorogenic acid dose for ameliorating cognitive impairment in APP/PS1 mice
10.1021/acs.jafc.2c06809 · 2023 · External reference
The bidirectional relationship of depression and inflammation: double trouble
10.1016/j.neuron.2020.06.002 · 2020 · External reference
Modulation of gut microbiota by chlorogenic acid pretreatment on rats with adrenocorticotropic hormone induced depression-like behavior
10.1039/c8fo02599a · 2019 · External reference
Cuscutae semen alleviates CUS-induced depression-like behaviors in mice via the gut microbiota-neuroinflammation axis
10.3389/fphar.2023.1107781 · 2023 · External reference
Apple polyphenol extract ameliorates sugary-diet-induced depression-like behaviors in male C57BL/6 mice by inhibiting the inflammation of the gut-brain axis
10.1039/d3fo04606k · 2024 · External reference
Apple polyphenol extracts attenuated depressive-like behaviors of high-sucrose diet feeding mice by farnesoid X receptor-mediated modulation of bile acid circulation within the liver-gut-brain axis
10.1021/acs.jafc.4c07035 · 2024 · External reference
Chlorogenic acid: a systematic review on the biological functions, mechanistic actions, and therapeutic potentials
10.3390/nu16070924 · 2024 · External reference
Geniposide plus chlorogenic acid reverses non-alcoholic steatohepatitis via regulation of gut microbiota and bile acid signaling in a mouse model in vivo
10.3389/fphar.2023.1148737 · 2023 · External reference
Multi-targeting therapeutic mechanisms of the Chinese herbal medicine QHD in the treatment of non-alcoholic fatty liver disease
10.18632/oncotarget.15482 · 2017 · External reference
The ameliorating effects of apple polyphenol extract on high-fat-diet-induced hepatic steatosis are SIRT1-dependent: evidence from hepatic-specific SIRT1 heterozygous mutant C57BL/6 mice
10.1021/acs.jafc.2c01461 · 2022 · External reference
The combination of sodium alginate and chlorogenic acid enhances the therapeutic effect on ulcerative colitis by the regulation of inflammation and the intestinal flora
10.1039/d2fo01619b · 2022 · External reference
Chlorogenic acid alleviates colon mucosal damage induced by a high-fat diet via gut microflora adjustment to increase short-chain fatty acid accumulation in rats
10.1155/2021/3456542 · 2021 · External reference
Supplemental plant extracts from Flos lonicerae in combination with Baikal skullcap attenuate intestinal disruption and modulate gut microbiota in laying hens challenged by Salmonella pullorum
10.3389/fmicb.2019.01681 · 2019 · External reference
Lycium barbarum L. leaves ameliorate type 2 diabetes in rats by modulating metabolic profiles and gut microbiota composition
10.1016/j.biopha.2019.109559 · 2020 · External reference