Research graph
References from Relationship Between Hypovitaminosis C, Obesity, and Features of Metabolic Syndrome—A Narrative Review. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Unresolved reference
2020 · External reference
Dietary fiber in the prevention of obesity and obesity-related chronic diseases: from epidemiological evidence to potential molecular mechanisms
10.1080/10408398.2022.2061909 · 2023 · External reference
Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
10.1016/s0140-6736(20)30752-2 · 2020 · External reference
Economic impacts of overweight and obesity: current and future estimates for 161 countries
10.1136/bmjgh-2022-009773 · 2022 · External reference
Nutritional load in post-prandial oxidative stress and the pathogeneses of diabetes mellitus
10.1038/s41538-024-00282-x · 2024 · External reference
Global impacts of Western diet and its effects on metabolism and health: a narrative review
10.3390/nu15122749 · 2023 · External reference
Regulation of glucose and lipid metabolism in health and disease
10.1007/s11427-019-1563-3 · 2019 · External reference
Vitamin C—a scoping review for Nordic Nutrition Recommendations 2023
10.29219/fnr.v67.10300 · 2023 · External reference
Inadequate vitamin C status in prediabetes and type 2 diabetes mellitus: associations with glycaemic control, obesity, and smoking
10.3390/nu9090997 · 2017 · External reference
Abnormal urinary loss of vitamin C in diabetes: prevalence and clinical characteristics of a vitamin C renal leak
10.1093/ajcn/nqac063 · 2022 · External reference
Vitamin C status in people with types 1 and 2 diabetes mellitus and varying degrees of renal dysfunction: relationship to body weight
10.3390/antiox11020245 · 2022 · External reference
Estimating vitamin C intake requirements in diabetes mellitus: analysis of NHANES 2017-2018 and EPIC-Norfolk cohorts
10.3390/antiox12101863 · 2023 · External reference
Vitamin C status and its change in relation to glucose-lipid metabolism in overweight and obesity patients following laparoscopic sleeve gastrectomy
10.1038/s41430-022-01134-1 · 2022 · External reference
Decreasing vitamin C intake, low serum vitamin C level and risk for US adults with diabetes
10.3390/nu14193902 · 2022 · External reference
A Healthy diet rich in calcium and vitamin C is inversely associated with metabolic syndrome risk in Korean adults from the KNHANES 2013-2017
10.3390/nu13041312 · 2021 · External reference
A systematized review of the relationship between obesity and vitamin C requirements
10.1016/j.cdnut.2024.102152 · 2024 · External reference
Global vitamin C status and prevalence of deficiency: a cause for concern?
10.3390/nu12072008 · 2020 · External reference
Vitamin C deficiency in an Australian cohort of metropolitan surgical patients
10.1016/j.pathol.2018.07.004 · 2018 · External reference
Prevalence, risk factors, and clinical outcomes of vitamin C deficiency in adult hospitalized patients in high-income countries: a scoping review
10.1093/nutrit/nuad157 · 2024 · External reference
A simple method for plasma total vitamin C analysis suitable for routine clinical laboratory use
10.1186/s12937-016-0158-9 · 2016 · External reference
Vitamin C status of Canadian adults: findings from the 2012/2013 Canadian Health Measures Survey
2016 · External reference
Vitamin C deficiency in a university teaching hospital
10.1080/07315724.2008.10719721 · 2008 · External reference
Re: “Vitamin C deficiency in a population of young Canadian adults.”
10.1093/aje/kwp400 · 2010 · External reference
Serum vitamin C status of people in New South Wales: retrospective analysis of findings at a public referral hospital
10.5694/mja2.52132 · 2023 · External reference
Vitamin C status of US adults assessed as part of the National Health and Nutrition Examination Survey remained unchanged between 2003-2006 and 2017-2018
10.1093/jalm/jfac093 · 2023 · External reference
The IDF definition is better suited for screening metabolic syndrome and estimating risks of diabetes in Asian American adults: evidence from NHANES 2011-2016
10.3390/jcm9123871 · 2020 · External reference
Molecular mechanisms of Western diet-induced obesity and obesity-related carcinogenesis—a narrative review
10.3390/metabo13050675 · 2023 · External reference
Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis
10.1080/15592294.2023.2211361 · 2023 · External reference
Racial disparities in methylation of NRF1, FTO, and LEPR gene in childhood obesity
10.3390/genes13112030 · 2022 · External reference
Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes
10.1038/s41467-023-38439-z · 2023 · External reference
An overview of epigenetics in obesity: the role of lifestyle and therapeutic interventions
10.3390/ijms23031341 · 2022 · External reference
Association between metabolic syndrome and mortality: prospective cohort study
10.2196/44073 · 2023 · External reference
Unresolved reference
2022 · External reference
Vitamin C—sources, physiological role, kinetics, deficiency, use, toxicity, and determination
10.3390/nu13020615 · 2021 · External reference
The genetics of vitamin C loss in vertebrates
10.2174/138920211796429736 · 2011 · External reference
Vitamin C in the treatment and/or prevention of obesity
10.3177/jnsv.60.367 · 2014 · External reference
Vitamin C: From nutrition to oxygen sensing and epigenetics
10.1016/j.redox.2023.102753 · 2023 · External reference
Vitamin C, biosynthesis, recycling and degradation in mammals
10.1111/j.1742-4658.2006.05607.x · 2007 · External reference
Vitamin C in human health and disease is still a mystery? An overview
10.1186/1475-2891-2-7 · 2003 · External reference
Ascorbic acid and connective tissue
10.1007/978-1-4613-0325-1_13 · 1996 · External reference
Vitamin C supplementation promotes mental vitality in healthy young adults: results from a cross-sectional analysis and a randomized, double-blind, placebo-controlled trial
10.1007/s00394-021-02656-3 · 2022 · External reference
Effects of different diets used in diet-induced obesity models on insulin resistance and vascular dysfunction in C57BL/6 mice
10.1038/s41598-019-55987-x · 2019 · External reference
The pharmacokinetics of vitamin C
10.3390/nu11102412 · 2019 · External reference
Vitamin C pharmacokinetics in healthy volunteers: evidence for a Recommended Dietary Allowance
10.1073/pnas.93.8.3704 · 1996 · External reference
New insights into the physiology and pharmacology of vitamin C
2001 · External reference
Vitamin C: the known and the unknown and Goldilocks
10.1111/odi.12446 · 2016 · External reference
Structure, function and regulation of mammalian glucose transporters of the SLC2 family
10.1007/s00424-020-02411-3 · 2020 · External reference
Abrupt termination of vitamin C from ICU patients may increase mortality: secondary analysis of the LOVIT trial
10.1038/s41430-022-01254-8 · 2023 · External reference
People with diabetes and hypovitaminosis C fail to conserve urinary vitamin C
10.1016/j.jcte.2023.100316 · 2023 · External reference
Ascorbic acid clearance in diabetic nephropathy
10.1016/s1056-8727(97)00125-6 · 1998 · External reference
Factors affecting the vitamin C dose-concentration relationship: implications for global vitamin C dietary recommendations
10.3390/nu15071657 · 2023 · External reference
Discrepancies in global vitamin C recommendations: a review of RDA criteria and underlying health perspectives
10.1080/10408398.2020.1744513 · 2021 · External reference
Renal excretion of ascorbic acid in insulin dependent diabetes mellitus
1994 · External reference
Concentrations of water-soluble vitamins in blood and urinary excretion in patients with diabetes mellitus
10.4137/nmi.s40595 · 2016 · External reference
Vitamin C and scar strength: analysis of a historical trial and implications for collagen-related pathologies
10.1093/ajcn/nqab262 · 2022 · External reference
Ascorbic acid requirements of adults: 30 mg or 75 mg?
10.1093/ajcn/6.2.146 · 1958 · External reference
Experimental scurvy in man
10.1093/ajcn/22.5.535 · 1969 · External reference
Unresolved reference
1989 · External reference
Are Recommended Daily Allowances for vitamin C adequate?
10.1073/pnas.71.11.4442 · 1974 · External reference
Factors affecting vitamin C status and prevalence of deficiency: a global health perspective
10.3390/nu12071963 · 2020 · External reference
Estimation of vitamin C intake requirements based on body weight: implications for obesity
10.3390/nu14071460 · 2022 · External reference
An increasing proportion of the population is not covered by the current RDA for vitamin C—interrogation of EPIC-Norfolk and NHANES 2017/2018 cohorts
10.1080/10408398.2024.2356760 · 2025 · External reference
Unresolved reference
2006 · External reference
10.17226/9810
10.17226/9810 · 2000 · External reference
Scientific opinion on dietary reference values for vitamin C
10.2903/j.efsa.2013.3418 · 2013 · External reference
The association between vitamin C dietary intake and its serum levels with anthropometric indices: a systematic review and meta-analysis
10.1016/j.ctcp.2023.101733 · 2023 · External reference
Emerging evidence on neutrophil motility supporting its usefulness to define vitamin C intake requirements
10.3390/nu9050503 · 2017 · External reference
Enhanced human neutrophil vitamin C status, chemotaxis and oxidant generation following dietary supplementation with vitamin C-rich SunGold kiwifruit
10.3390/nu7042574 · 2015 · External reference
Vitamin C modulates the interaction between adipocytes and macrophages
10.1002/mnfr.201100296 · 2011 · External reference
Effects of antioxidants in reducing accumulation of fat in hepatocyte
10.3390/ijms19092563 · 2018 · External reference
Ascorbic acid attenuates cell stress by activating the fibroblast growth factor 21/fibroblast growth factor receptor 2/adiponectin pathway in HepG2 cells
10.3892/mmr.2019.10457 · 2019 · External reference
Vitamins E and C do not effectively inhibit low density lipoprotein oxidation by ferritin at lysosomal pH
10.1080/10715762.2021.1964494 · 2021 · External reference
Efficacy of antioxidant treatment in reducing resistin serum levels: a randomized study
10.1371/journal.pctr.0020017 · 2007 · External reference
Antioxidant effects of vitamins in type 2 diabetes: a meta-analysis of randomized controlled trials
10.1186/s13098-018-0318-5 · 2018 · External reference
Contribution of a high dose of L-ascorbic acid to carnitine synthesis in guinea pigs fed high-fat diets
10.3177/jnsv.45.163 · 1999 · External reference
Vitamin C depletion is associated with alterations in blood histamine and plasma free carnitine in adults
10.1080/07315724.1996.10718634 · 1996 · External reference
Marginal vitamin C status is associated with reduced fat oxidation during submaximal exercise in young adults
10.1186/1743-7075-3-35 · 2006 · External reference
Vitamin C suppresses TNF alpha-induced NF kappa B activation by inhibiting I kappa B alpha phosphorylation
10.1021/bi0263210 · 2002 · External reference
Synergistic effects of ascorbic acid and thiazolidinedione on secretion of high molecular weight adiponectin from human adipocytes
10.1111/j.1463-1326.2010.01297.x · 2010 · External reference
Vitamin C inhibits leptin secretion and some glucose/lipid metabolic pathways in primary rat adipocytes
10.1677/jme-09-0160 · 2010 · External reference
Vitamin C protects against hypoxia, inflammation, and ER stress in primary human preadipocytes and adipocytes
10.1016/j.mce.2022.111740 · 2022 · External reference
Dietary factors associated with subclinical inflammation among girls
10.1038/ejcn.2013.196 · 2013 · External reference
Effect of ascorbic acid and alpha-tocopherol supplementations on serum leptin, tumor necrosis factor alpha, and serum amyloid A levels in individuals with type 2 diabetes mellitus
2015 · External reference
Effects of oral vitamin C supplementation on liver health and associated parameters in patients with non-alcoholic fatty liver disease: a randomized clinical trial. Clinical trial
10.3389/fnut.2021.745609 · 2021 · External reference
Vitamin C inhibits visceral adipocyte hypertrophy and lowers blood glucose levels in high-fat-diet-induced obese C57BL/6J mice
10.15616/bsl.2018.24.4.311 · 2018 · External reference
Ascorbic acid reduces insulin resistance and pancreatic steatosis by regulating adipocyte hypertrophy in obese ovariectomized mice
10.1139/cjpp-2022-0339 · 2023 · External reference
Combined effect of metformin with ascorbic acid versus acetyl salicylic acid on diabetes-related cardiovascular complication; a 12-month single blind multicenter randomized control trial
10.1186/s12933-017-0584-9 · 2017 · External reference
Effects of vitamin C supplementation on glycemic control and cardiovascular risk factors in people with type 2 diabetes: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials
10.2337/dc20-1893 · 2021 · External reference
Hypovitaminosis C and cholelithiasis in guinea pigs
10.1016/s0006-291x(77)80081-8 · 1977 · External reference
The effect of vitamin C in high doses on plasma and biliary lipid composition in patients with cholesterol gallstones: prolongation of the nucleation time
10.1046/j.1365-2362.1997.1240670.x · 1997 · External reference
Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression
10.1074/jbc.ra120.015623 · 2020 · External reference
Lack of effect of experimental ascorbic acid deficiency on bile acid metabolism, sterol balance, and biliary lipid composition in man
10.1016/s0022-2275(20)37902-5 · 1983 · External reference
Vitamin C supplement use may protect against gallstones: an observational study on a randomly selected population
10.1186/1471-230x-9-74 · 2009 · External reference
Vitamin C and vitamin D(3) alleviate metabolic-associated fatty liver disease by regulating the gut microbiota and bile acid metabolism via the gut-liver axis
10.3389/fphar.2023.1163694 · 2023 · External reference
Collagen release by human hepatic stellate cells requires vitamin C and is efficiently blocked by hydroxylase inhibition
10.1096/fj.202001564rr · 2021 · External reference
Ascorbic acid inhibits transcriptional activities of LXRα to ameliorate lipid metabolism disorder
10.1016/j.jff.2021.104901 · 2022 · External reference
Amelioration of diet-induced nonalcoholic steatohepatitis in rats by Mn-salen complexes via reduction of oxidative stress
10.1186/1423-0127-19-26 · 2012 · External reference
Mega-dose vitamin C ameliorates nonalcoholic fatty liver disease in a mouse fast-food diet model
10.3390/nu14112195 · 2022 · External reference
Liver histological improvement after administration of high-dose vitamin C in guinea pig with nonalcoholic steatohepatitis
10.1024/0300-9831/a000515 · 2018 · External reference
Prophylactic and therapeutic effects of different doses of vitamin C on high-fat-diet-induced non-alcoholic fatty liver disease in mice
10.1016/j.biopha.2020.110792 · 2020 · External reference
Vitamin C deficiency inhibits nonalcoholic fatty liver disease progression through impaired de novo lipogenesis
10.1016/j.ajpath.2021.05.020 · 2021 · External reference
Vitamin C deficiency may delay diet-induced NASH regression in the guinea pig
10.3390/antiox11010069 · 2021 · External reference
Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis
10.1016/j.amjgastroenterol.2003.08.005 · 2003 · External reference
A cross-sectional study assessing dietary intake and physical activity in Canadian patients with nonalcoholic fatty liver disease vs healthy controls
10.1016/j.jand.2014.01.009 · 2014 · External reference
Comparative analysis of efficiency of ursodeoxycholic acid combination of vitamin E and vitamin C in treatment of non-diabetic nonalcoholic steatohepatitis
2019 · External reference
Association of serum vitamin C with NAFLD and MAFLD among adults in the United States
10.3389/fnut.2021.795391 · 2021 · External reference
A double blind placebo controlled trial of ascorbic acid in obesity
10.1177/026010618500400104 · 1985 · External reference
Metabolic benefits deriving from chronic vitamin C supplementation in aged non-insulin dependent diabetics
10.1080/07315724.1995.10718526 · 1995 · External reference
Zinc, vitamin A, and vitamin C status are associated with leptin concentrations and obesity in Mexican women: results from a cross-sectional study
10.1186/1743-7075-9-59 · 2012 · External reference
Dietary ascorbic acid and subsequent change in body weight and waist circumference: associations may depend on genetic predisposition to obesity—a prospective study of three independent cohorts
10.1186/1475-2891-13-43 · 2014 · External reference
Vitamin C and metabolic syndrome: a meta-analysis of observational studies
10.3389/fnut.2021.728880 · 2021 · External reference
Association of serum water-soluble vitamin exposures with the risk of metabolic syndrome: results from NHANES 2003-2006
10.3389/fendo.2023.1167317 · 2023 · External reference
A high vitamin C micronutrient supplement is unable to attenuate inflammation in people with metabolic syndrome but may improve metabolic health indices: a randomised controlled trial
10.3390/antiox13040404 · 2024 · External reference
Effect of vitamin C supplementation on blood pressure level in type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial
10.13005/bbra/2031 · 2016 · External reference
Ascorbic acid supplementation improves postprandial glycaemic control and blood pressure in individuals with type 2 diabetes: findings of a randomized cross-over trial
10.1111/dom.13571 · 2019 · External reference
Nuclear and cytoplasmic functions of vitamin C
10.1021/acs.chemrestox.0c00348 · 2020 · External reference
Defining ROS in biology and medicine
10.20455/ros.2016.803 · 2016 · External reference
Superoxide radicals in the execution of cell death
10.3390/antiox11030501 · 2022 · External reference
Vitamin C in health and disease: its role in the metabolism of cells and redox state in the brain
10.3389/fphys.2015.00397 · 2015 · External reference
Oxidative stress in obesity: a critical component in human diseases
10.3390/ijms16010378 · 2014 · External reference
Roles of reactive oxygen species on insulin resistance in adipose tissue
10.4093/dmj.2016.40.4.272 · 2016 · External reference
From flies to men: ROS and the NADPH oxidase in phagocytes
10.3389/fcell.2021.628991 · 2021 · External reference
Cellular senescence and its role in white adipose tissue
10.1038/s41366-021-00757-x · 2021 · External reference
Oxidative stress and potential interventions to reduce oxidative stress in overweight and obesity
10.1111/j.1463-1326.2007.00692.x · 2007 · External reference
Systemic oxidative alterations are associated with visceral adiposity and liver steatosis in patients with metabolic syndrome
10.1093/jn/136.12.3022 · 2006 · External reference
Two faces of vitamin C-antioxidative and pro-oxidative agent
10.3390/nu12051501 · 2020 · External reference
Mechanism of chemiluminescence in Fenton reaction
10.4236/jbpc.2012.31011 · 2012 · External reference
The roles of vitamin C in skin health
10.3390/nu9080866 · 2017 · External reference
The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate
10.1006/abbi.1993.1074 · 1993 · External reference
The effects of hormone replacement therapy combined with vitamins C and E on antioxidants levels and lipid profiles in postmenopausal women with type 2 diabetes
10.1016/j.cccn.2004.01.031 · 2004 · External reference
Redox balance in type 2 diabetes: therapeutic potential and the challenge of antioxidant-based therapy
10.3390/antiox12050994 · 2023 · External reference
Intracellular sources of ROS/H(2)O(2) in health and neurodegeneration: spotlight on endoplasmic reticulum
10.3390/cells10020233 · 2021 · External reference
The role of ascorbate in protein folding
10.1007/s00709-013-0560-5 · 2014 · External reference
Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury
10.1016/j.febslet.2005.04.058 · 2005 · External reference
The role of the Nrf2 signaling in obesity and insulin resistance
10.3390/ijms21186973 · 2020 · External reference
Two distinct faces of vitamin C: AA vs. DHA
10.3390/antiox10020215 · 2021 · External reference
Vitamin C supplementation slightly improves physical activity levels and reduces cold incidence in men with marginal vitamin C status: a randomized controlled trial
10.3390/nu6072572 · 2014 · External reference
Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism
10.1196/annals.1320.003 · 2004 · External reference
Metabolic interactions between peroxisomes and mitochondria with a special focus on acylcarnitine metabolism
10.1016/j.bbadis.2020.165720 · 2020 · External reference
The carnitine system and body composition
10.1007/s00592-003-0040-z · 2003 · External reference
The role of carnitine in normal and altered fatty acid metabolism
10.1016/s0272-6386(03)00112-4 · 2003 · External reference
Ascorbic acid and carnitine biosynthesis
10.1093/ajcn/54.6.1147s · 1991 · External reference
Ascorbate indirectly stimulates fatty acid utilization in primary cultured guinea pig hepatocytes by enhancing carnitine synthesis
10.1093/jn/124.5.732 · 1994 · External reference
High vitamin C status is associated with elevated mood in male tertiary students
10.3390/antiox7070091 · 2018 · External reference
Vitamin C status and perception of effort during exercise in obese adults adhering to a calorie-reduced diet
10.1016/j.nut.2012.01.021 · 2013 · External reference
The ability of guinea pigs to synthesize carnitine at a normal rate from epsilon-N-trimethyllysine or gamma-butyrobetaine in vivo is not compromised by experimental vitamin C deficiency
10.1016/0026-0495(95)90120-5 · 1995 · External reference
Vitamin C is not essential for carnitine biosynthesis in vivo: verification in vitamin C-depleted senescence marker protein-30/gluconolactonase knockout mice
10.1248/bpb.31.1673 · 2008 · External reference
Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease
10.1186/s13073-022-01071-5 · 2022 · External reference
The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes
10.1038/ijo.2015.31 · 2015 · External reference
PPARγ-induced PARylation promotes local DNA demethylation by production of 5-hydroxymethylcytosine
10.1038/ncomms3262 · 2013 · External reference
Vitamin C inhibits the metabolic changes induced by Tet1 insufficiency under high fat diet stress
10.1002/mnfr.202100417 · 2021 · External reference
5mC profiling characterized TET2 as an anti-adipogenic demethylase
10.1016/j.gene.2019.144265 · 2020 · External reference
Emerging roles of epigenetic regulation in obesity and metabolic disease
10.1016/j.jbc.2021.101296 · 2021 · External reference
Loss of adipose TET proteins enhances β-adrenergic responses and protects against obesity by epigenetic regulation of β3-AR expression
10.1073/pnas.2205626119 · 2022 · External reference
Adipokines mediate inflammation and insulin resistance
10.3389/fendo.2013.00071 · 2013 · External reference
Role of innate and adaptive immunity in obesity-associated metabolic disease
10.1172/jci88876 · 2017 · External reference
Beneficial effects of adiponectin on glucose and lipid metabolism and atherosclerotic progression: mechanisms and perspectives
10.3390/ijms20051190 · 2019 · External reference
Adiponectin and adiponectin receptors
10.1210/er.2005-0005 · 2005 · External reference
Plasma vitamin C is inversely related to body mass index and waist circumference but not to plasma adiponectin in nonsmoking adults
10.1093/jn/137.7.1757 · 2007 · External reference
Modulation of hypoxia-inducible factor-1 alpha in cultured primary cells by intracellular ascorbate
10.1016/j.freeradbiomed.2006.11.023 · 2007 · External reference
Regulation of HIF-1{alpha} activity in adipose tissue by obesity-associated factors: adipogenesis, insulin, and hypoxia
10.1152/ajpendo.00626.2010 · 2011 · External reference
HIF-1α as a mediator of insulin resistance, T2DM, and its complications: potential links with obstructive sleep apnea
10.3389/fphys.2020.01035 · 2020 · External reference
Hypoxia-inducible factor 1α regulates a SOCS3-STAT3-adiponectin signal transduction pathway in adipocytes
10.1074/jbc.m112.426338 · 2013 · External reference
The role of leptin in the control of insulin-glucose axis
10.3389/fnins.2013.00051 · 2013 · External reference
The endoplasmic reticulum stress-autophagy pathway controls hypothalamic development and energy balance regulation in leptin-deficient neonates
10.1038/s41467-020-15624-y · 2020 · External reference
Dehydroascorbic acid-induced endoplasmic reticulum stress and leptin resistance in neuronal cells
10.1016/j.bbrc.2016.08.013 · 2016 · External reference
Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes
10.2337/diabetes.47.10.1562 · 1998 · External reference
Exercise-stimulated ROS sensitive signaling pathways in skeletal muscle
10.3390/antiox10040537 · 2021 · External reference
Ascorbic acid supplementation in type 2 diabetes mellitus: a protocol for systematic review and meta-analysis
10.1097/md.0000000000023125 · 2020 · External reference
Cellular senescence and extracellular vesicles in the pathogenesis and treatment of obesity—a narrative review
10.3390/ijms25147943 · 2024 · External reference
Ascorbic acid is a stimulatory cofactor for mitochondrial glycerol-3-phosphate dehydrogenase
10.1006/bbrc.1997.7438 · 1997 · External reference
The GAPDH redox switch safeguards reductive capacity and enables survival of stressed tumour cells
10.1038/s42255-023-00781-3 · 2023 · External reference
Mitochondrial management of reactive oxygen species
10.3390/antiox10111824 · 2021 · External reference
Pathogenesis of chronic hyperglycemia: from reductive stress to oxidative stress
10.1155/2014/137919 · 2014 · External reference
Involvement of senescence marker protein-30 in glucose metabolism disorder and non-alcoholic fatty liver disease
10.1111/ggi.12722 · 2016 · External reference
The fructose survival hypothesis for obesity
10.1098/rstb.2022.0230 · 2023 · External reference
Therapeutic interventions and oxidative stress in diabetes
10.2741/3240 · 2009 · External reference
Oxidative stress in type 2 diabetes: impacts from pathogenesis to lifestyle modifications
10.3390/cimb45080420 · 2023 · External reference
Unresolved reference
2025 · External reference
A causal relationship between vitamin C intake with hyperglycemia and metabolic syndrome risk: a two-sample Mendelian randomization study
10.3390/antiox11050857 · 2022 · External reference
Enhanced oxidative stress and damage in glycated erythrocytes
10.1371/journal.pone.0235335 · 2020 · External reference
Erythrocyte osmotic fragility is not linked to vitamin C nutriture in adults with well-controlled type 2 diabetes
10.3389/fnut.2022.954010 · 2022 · External reference
Pathophysiology of red blood cell dysfunction in diabetes and its complications
10.3390/pathophysiology30030026 · 2023 · External reference
Vegetarian diet improves insulin resistance and oxidative stress markers more than conventional diet in subjects with type 2 diabetes
10.1111/j.1464-5491.2010.03209.x · 2011 · External reference
Could nutrient supplements provide additional glycemic control in diabetes management? A systematic review and meta-analysis of randomized controlled trials of as an add-on nutritional supplementation therapy
10.1007/s12272-022-01374-6 · 2022 · External reference
Effects of vitamin C supplementation on glycaemic control: a systematic review and meta-analysis of randomised controlled trials
10.1038/ejcn.2017.24 · 2017 · External reference
Multivitamins, individual vitamin and mineral supplements, and risk of diabetes among older U.S. adults
10.2337/dc10-1260 · 2011 · External reference
Ascorbic acid supplementation improves skeletal muscle oxidative stress and insulin sensitivity in people with type 2 diabetes: findings of a randomized controlled study
10.1016/j.freeradbiomed.2016.01.006 · 2016 · External reference
Vitamin C attenuates predisposition to high-fat diet-induced metabolic dysregulation in GLUT10-deficient mouse model
10.1186/s12263-022-00713-y · 2022 · External reference
Arterial tortuosity syndrome: an ascorbate compartmentalization disorder?
10.1089/ars.2019.7843 · 2021 · External reference
Cellular compartmentalization, glutathione transport and its relevance in some pathologies
10.3390/antiox12040834 · 2023 · External reference
The association of metabolic syndrome and its factors with gallstone disease
10.1186/1471-2296-15-138 · 2014 · External reference
Causal association between metabolic syndrome and cholelithiasis: a Mendelian randomization study
10.3389/fendo.2023.1180903 · 2023 · External reference
Cholesterol: vitamin C controls its transformation to bile acids
10.1126/science.179.4074.702 · 1973 · External reference
Discovery of farnesoid X receptor and its role in bile acid metabolism
10.1016/j.mce.2022.111618 · 2022 · External reference
Vitamin C and plasma cholesterol
10.1080/10408399209527579 · 1992 · External reference
Human cholesterol 7alpha-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype
10.1172/jci15387 · 2002 · External reference
Associations of the CYP7A1 gene polymorphisms located in the promoter and enhancer regions with the risk of acute coronary syndrome, plasma cholesterol, and the incidence of diabetes
10.3390/biomedicines12030617 · 2024 · External reference
Role of marginal vitamin C deficiency in atherogenesis: in vivo models and clinical studies
10.1111/j.1742-7843.2009.00420.x · 2009 · External reference
Vitamin C deficiency, cholesterol metabolism, and atherosclerosis
1991 · External reference
A high-fat diet is associated with endotoxemia that originates from the gut
10.1053/j.gastro.2012.01.034 · 2012 · External reference
The role of short-chain fatty acids in the interplay between gut microbiota and diet in cardio-metabolic health
10.1080/19490976.2021.1897212 · 2021 · External reference
Health effects and sources of prebiotic dietary fiber
10.1093/cdn/nzy005 · 2018 · External reference
Endotoxin producers overgrowing in human gut microbiota as the causative agents for nonalcoholic fatty liver disease
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