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References from Patient‑specific profiling of TCR‑T cell efficacy enabled by a rapid and standardized reporter system. Local targets link to admitted publications; unresolved targets remain external evidence.
Jurkat T cells and development of the T-cell receptor signalling paradigm
10.1038/nri1330 · 2004 · External reference
FDA approval summary: Afamitresgene autoleucel for adults with HLA-Restricted, MAGE-A4-Positive unresectable or metastatic synovial sarcoma after prior chemotherapy
10.1158/1078-0432.ccr-25-0595 · 2025 · External reference
TCR-engineered T cell therapy in solid tumors: state of the art and perspectives
10.1126/sciadv.adf3700 · 2023 · External reference
The genomic landscape of 2,023 colorectal cancers
10.1038/s41586-024-07747-9 · 2024 · External reference
A few good peptides: MHC class I-based cancer immunosurveillance and immunoevasion
10.1038/s41577-020-0390-6 · 2021 · External reference
Detection of cancer cells and tumor margins during colorectal cancer surgery by intraoperative flow cytometry
10.1016/j.ijsu.2022.106717 · 2022 · External reference
The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity
10.1016/j.ccell.2023.05.014 · 2023 · External reference
Regulatory mechanisms of PD-1/PD-L1 in cancers
10.1186/s12943-024-02023-w · 2024 · External reference
Immunologic recognition of a shared p53 mutated neoantigen in a patient with metastatic colorectal cancer
10.1158/2326-6066.cir-18-0686 · 2019 · External reference
TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers
10.1038/s41591-020-01225-1 · 2021 · External reference
T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
10.1038/mt.2010.272 · 2011 · External reference
TCR catch bonds nonlinearly control CD8 cooperation to shape T cell specificity
10.1038/s41422-025-01077-9 · 2025 · External reference
BATF and IRF4 cooperate to counter exhaustion in tumor-infiltrating CAR T cells
10.1038/s41590-021-00964-8 · 2021 · External reference
Prospective derivation of a living organoid biobank of colorectal cancer patients
10.1016/j.cell.2015.03.053 · 2015 · External reference
