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References from Dimethyl Fumarate Mediates Glutathione Metabolism to Drive Cuproptosis and Activate the Antitumor Function of CD8+ T Cells Against Liver Cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Recent trends in liver cancer: epidemiology, risk factors, and diagnostic techniques
2024 · External reference
Advances in the surgical treatment of liver cancer
10.5582/bst.2022.01245 · 2022 · External reference
Immunotherapy in liver cancer: overcoming the tolerogenic liver microenvironment
10.3389/fimmu.2024.1460282 · 2024 · External reference
Exploring markers of exhausted CD8 T cells to predict response to immune checkpoint inhibitor therapy for hepatocellular carcinoma
10.1159/000515305 · 2021 · External reference
Cross-talk between cuproptosis and ferroptosis regulators defines the tumor microenvironment for the prediction of prognosis and therapies in lung adenocarcinoma
10.3389/fimmu.2022.1029092 · 2022 · External reference
Copper homeostasis and cuproptosis in health and disease
10.1038/s41392-022-01229-y · 2022 · External reference
Cuproptosis and copper as potential mechanisms and intervention targets in Alzheimer’s disease
10.1016/j.biopha.2025.117814 · 2025 · External reference
Nano-drug design based on the physiological properties of glutathione
10.3390/molecules26185567 · 2021 · External reference
NFE2L2 and SLC25A39 drive cuproptosis resistance through GSH metabolism
10.1038/s41598-024-81317-x · 2024 · External reference
Nanoenhanced-cuproptosis results from the synergy of calcium overload and GSH depletion with the increasing of intracellular Ca/Mn/Cu ions
10.1002/advs.202412067 · 2025 · External reference
Dimethyl fumarate and intestine: from main suspect to potential ally against gut disorders
10.3390/ijms24129912 · 2023 · External reference
Dimethyl fumarate ameliorates doxorubicin-induced cardiotoxicity by activating the Nrf2 pathway
10.3389/fphar.2022.872057 · 2022 · External reference
Developmental impacts of Nrf2 activation by dimethyl fumarate (DMF) in the developing zebrafish (Danio rerio) embryo
10.1016/j.freeradbiomed.2022.12.013 · 2023 · External reference
Dimethyl fumarate ameliorates erectile dysfunction in bilateral cavernous nerve injury rats by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis of nerve via activation of Nrf2/HO-1 signaling pathway
10.1016/j.redox.2023.102938 · 2023 · External reference
Dimethyl fumarate controls the NRF2/DJ-1 axis in cancer cells: therapeutic applications
10.1158/1535-7163.mct-16-0405 · 2017 · External reference
Retinoid X receptor alpha (RXRalpha)-mediated erythroid-2-related factor-2 (NRF2) inactivation contributes to N,N-dimethylformamide (DMF)-induced oxidative stress in HL-7702 and HuH6 cells
10.1002/jat.3919 · 2020 · External reference
Dimethyl fumarate, a two-edged drug: current status and future directions
10.1002/med.21567 · 2019 · External reference
Utilization of dimethyl fumarate and related molecules for treatment of multiple sclerosis, cancer, and other diseases
10.3389/fimmu.2016.00278 · 2016 · External reference
Nrf2 signaling in the oxidative stress response after spinal cord injury
10.1016/j.neuroscience.2022.06.007 · 2022 · External reference
Tanshinone I induces mitochondrial protection by a mechanism involving the Nrf2/GSH axis in the human neuroblastoma SH-SY5Y cells exposed to methylglyoxal
10.1007/s12640-019-00091-1 · 2019 · External reference
Dynamic modeling of Nrf2 pathway activation in liver cells after toxicant exposure
10.1038/s41598-022-10857-x · 2022 · External reference
Dimethyl fumarate reduces methylglyoxal-derived carbonyl stress through Nrf2/GSH activation in SH-SY5Y Cells
10.1007/s11064-024-04255-0 · 2024 · External reference
Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway
10.1111/bph.13184 · 2015 · External reference
Cuproptosis scoring system to predict the clinical outcome and immune response in bladder cancer
10.3389/fimmu.2022.958368 · 2022 · External reference
High expression of cuproptosis-related gene FDX1 in relation to good prognosis and immune cells infiltration in colon adenocarcinoma (COAD)
10.1007/s00432-022-04382-7 · 2023 · External reference
Cuproptosis in microsatellite stable colon cancer cells affects the cytotoxicity of CD8(+)T through the WNT signaling pathway
10.1016/j.cbi.2024.111239 · 2024 · External reference
Cytotoxic CD4(+) T cells in cancer: expanding the immune effector toolbox
10.1016/j.immuni.2021.11.015 · 2021 · External reference
