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References from Comprehensive analysis and external validation of a glycolysis-related gene signature as a prognostic index for skin cutaneous melanoma. Local targets link to admitted publications; unresolved targets remain external evidence.
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Evaluation of the agreement between TNM 7th and 8th in a population-based series of cutaneous melanoma.
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A second cohort of CHD3 patients expands the molecular mechanisms known to cause Snijders Blok-Campeau syndrome.
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Bulk and single-cell transcriptome profiling reveal the metabolic heterogeneity in human breast cancers.
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PML-regulated mitochondrial metabolism enhances chemosensitivity in human ovarian cancers.
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Linking tumor glycolysis and immune evasion in cancer: emerging concepts and therapeutic opportunities.
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Recent advances in immunotherapy for the treatment of malignant melanoma.
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A role of immunotherapy in metastatic malignant melanoma.
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Systematic pan-cancer analysis reveals immune cell interactions in the tumor microenvironment.
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Five-year survival outcomes for patients with advanced melanoma treated with pembrolizumab in KEYNOTE-001.
10.1093/annonc/mdz011 · 2019 · External reference
Five-year survival with combined nivolumab and ipilimumab in advanced melanoma.
10.1056/nejmoa1910836 · 2019 · External reference
Combined BRAF and MEK inhibition with PD-1 blockade immunotherapy in BRAF-mutant melanoma.
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Neoadjuvant checkpoint immunotherapy and melanoma: the time is now.
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Emerging therapeutic targets for patients with advanced prostate cancer.
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Mechanisms and implications of metabolic heterogeneity in cancer.
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Integrating canonical and metabolic signalling programmes in the regulation of T cell responses.
10.1038/nri3701 · 2014 · External reference
Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond.
10.1016/j.pharmthera.2008.09.005 · 2009 · External reference
Development and validation of a novel T cell proliferation-related prognostic model for predicting survival and immunotherapy benefits in melanoma.
10.18632/aging.204748 · 2023 · External reference
Immunotherapy in the treatment of metastatic melanoma: current knowledge and future directions.
10.1155/2020/9235638 · 2020 · External reference
Melanoma treatment in review.
10.2147/itt.s134842 · 2018 · External reference
Tumor glycolysis as a target for cancer therapy: progress and prospects.
10.1186/1476-4598-12-152 · 2013 · External reference
Increased glycolysis correlates with elevated immune activity in tumor immune microenvironment.
10.1016/j.ebiom.2019.03.068 · 2019 · External reference
CD4(+) T-cell differentiation and function: unifying glycolysis, fatty acid oxidation, polyamines NAD mitochondria.
10.1016/j.jaci.2021.03.033 · 2021 · External reference
Ablation of proton/glucose exporter SLC45A2 enhances melanosomal glycolysis to inhibit melanin biosynthesis and promote melanoma metastasis.
10.1016/j.jid.2022.04.008 · 2022 · External reference
Glycolysis regulator PFKP induces human melanoma cell proliferation and tumor growth.
10.1007/s12094-023-03096-7 · 2023 · External reference
Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context.
10.7554/elife.73245 · 2022 · External reference
GOT2: an unexpected mediator of immunosuppression in pancreatic cancer.
10.1158/2159-8290.cd-22-0845 · 2022 · External reference
Combining single-cell and transcriptomic analysis revealed the immunomodulatory effect of GOT2 on a glutamine-dependent manner in cutaneous melanoma.
10.3389/fphar.2023.1241454 · 2023 · External reference
Flupirtine blocks apoptosis in batten patient lymphoblasts and in human postmitotic CLN3- and CLN2-deficient neurons.
10.1002/ana.10143 · 2002 · External reference
TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma.
10.1126/science.abq0607 · 2022 · External reference
Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells.
10.1016/j.cmet.2012.10.017 · 2012 · External reference
Metabolic reprogramming in metastatic melanoma with acquired resistance to targeted therapies: integrative metabolomic and proteomic analysis.
10.3390/cancers12051323 · 2020 · External reference
Glycogen synthase 1 targeting reveals a metabolic vulnerability in triple-negative breast cancer.
10.1186/s13046-023-02715-z · 2023 · External reference
Mucopolysaccharidoses type I gene therapy.
10.1002/jimd.12414 · 2021 · External reference
GYS1 induces glycogen accumulation and promotes tumor progression via the NF-kappaB pathway in clear cell renal carcinoma.
10.7150/thno.46825 · 2020 · External reference
A metabolism-driven prognostic model and PSMD14-SP1-GYS1 axis reveal therapeutic vulnerabilities in melanoma.
10.1016/j.jid.2025.08.044 · 2026 · External reference
Tertiary lymphoid structures improve immunotherapy and survival in melanoma.
10.1038/s41586-019-1914-8 · 2020 · External reference
B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma.
10.1038/s41467-019-12160-2 · 2019 · External reference
Innate stimulation of B cells ex vivo enhances antibody secretion and identifies tumour-reactive antibodies from cancer patients.
10.1093/cei/uxab005 · 2022 · External reference
Neoadjuvant versus adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma.
10.1038/s41591-018-0198-0 · 2018 · External reference
Immunomodulation of the tumor microenvironment: turn foe into friend.
10.3389/fimmu.2018.02909 · 2018 · External reference
The role of myeloid-derived suppressor cells (MDSC) in cancer progression.
10.3390/vaccines4040036 · 2016 · External reference
Escape from NK cell tumor surveillance by NGFR-induced lipid remodeling in melanoma.
10.1126/sciadv.adc8825 · 2023 · External reference
The clinical role of the TME in solid cancer.
10.1038/s41416-018-0327-z · 2019 · External reference
Multiplex quantitative analysis of cancer-associated fibroblasts and immunotherapy outcome in metastatic melanoma.
10.1186/s40425-019-0675-0 · 2019 · External reference
Melanoma.
10.1016/s0140-6736(18)31559-9 · 2018 · External reference
Treatment of metastatic uveal melanoma with intravenous fotemustine.
10.1097/cmr.0b013e3283610586 · 2013 · External reference
Is there still a role for cytotoxic chemotherapy after targeted therapy and immunotherapy in metastatic melanoma? A case report and literature review.
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