Research graph
References from Machine Learning Models Integrating CYP2C19 Genotypes for Long-Term Risk Prediction and Personalized Antiplatelet Therapy Selection in Myocardial Infarction. Local targets link to admitted publications; unresolved targets remain external evidence.
Acute coronary syndromes
10.1016/s0140-6736(21)02391-6 · 2022 · External reference
Transforming cardiovascular care with artificial intelligence: from discovery to practice: JACC state-of-the-art review
10.1016/j.jacc.2024.05.003 · 2024 · External reference
CYP2C19 activity and cardiovascular risk factors in patients with an acute coronary syndrome
10.1016/j.medcli.2017.02.035 · 2017 · External reference
Updated expert consensus statement on platelet function and genetic testing for guiding P2Y(12) receptor inhibitor treatment in percutaneous coronary intervention
10.1016/j.jcin.2019.03.034 · 2019 · External reference
Residual inflammatory risk: a common and important risk factor for recurrent cardiovascular events
10.1016/j.jacc.2019.02.056 · 2019 · External reference
The comprehensive complication index is related to frailty in elderly surgical patients
10.1016/j.jss.2019.06.011 · 2019 · External reference
MLxtend: providing machine learning and data science utilities and extensions to Python's scientific computing stack
10.21105/joss.00638 · 2018 · External reference
CatBoost: unbiased boosting with categorical features
2018 · External reference
A unified approach to interpreting model predictions
2017 · External reference
CYP2C19*2 and prognosis after an acute coronary syndrome: insights from a Portuguese center
10.1016/j.repc.2012.02.001 · 2012 · External reference
Association of different CYP2C19 genotypes with clopidogrel efficacy and adverse cardiovascular events during hospitalization in patients with ACS
2020 · External reference
Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis
10.1001/jama.2010.1543 · 2010 · External reference
Genetic polymorphism of CYP2C19 gene in the stanislas cohort. A link with inflammation
10.1111/j.1469-1809.2007.00417.x · 2008 · External reference
CYP2C19 poor metabolizer status and high system inflammation response index are independent risk factors for premature myocardial infarction: a hospital-based retrospective study
10.2147/ijgm.s489235 · 2024 · External reference
The combination of CYP2C19 polymorphism and inflammatory cell ratios in prognosis cardiac adverse events after acute coronary syndrome
2023 · External reference
Role of genetic polymorphisms in clopidogrel response variability: a systematic review
10.1136/openhrt-2023-002436 · 2023 · External reference
The efficacy and safety of CYP2C19 genotype-guided antiplatelet therapy compared with conventional antiplatelet therapy in patients with acute coronary syndrome or undergoing percutaneous coronary intervention: a meta-analysis of randomized controlled trials
10.1080/09537104.2020.1780205 · 2020 · External reference
Effect of CYP2C19 genotype on ischemic outcomes during oral P2Y(12) inhibitor therapy: a meta-analysis
10.1016/j.jcin.2021.01.024 · 2021 · External reference
A genotype-guided strategy for oral P2Y(12) inhibitors in primary PCI
10.1056/nejmoa1907096 · 2019 · External reference
Effect of genotype-guided oral P2Y12 inhibitor selection vs conventional clopidogrel therapy on ischemic outcomes after percutaneous coronary intervention: the TAILOR-PCI randomized clinical trial
10.1001/jama.2020.12443 · 2020 · External reference
Ticagrelor is more effective than clopidogrel in carrier of nonfunctional CYP2C19 allele who has diabetes and acute coronary syndrome-case report and literature review
10.3934/molsci.2022004 · 2022 · External reference
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
10.1056/nejmoa0904327 · 2009 · External reference
Machine learning-based prediction of adverse events following an acute coronary syndrome (PRAISE): a modelling study of pooled datasets
10.1016/s0140-6736(20)32519-8 · 2021 · External reference
Prediction of longitudinal clinical outcomes after acute myocardial infarction using a dynamic machine learning algorithm
10.3389/fcvm.2024.1340022 · 2024 · External reference
A benchmark study of deep learning-based multi-omics data fusion methods for cancer
10.1186/s13059-022-02739-2 · 2022 · External reference