Research graph
References from Prospective study of reproductive span and menopausal hormone therapy and cognitive decline over 8 years in the Nurses’ Health Study. Local targets link to admitted publications; unresolved targets remain external evidence.
Sex differences in cognitive decline among US adults
10.1001/jamanetworkopen.2021.0169 · 2021 · External reference
The role of estrogen in brain and cognitive aging
10.1007/s13311-019-00766-9 · 2019 · External reference
Neurotrophic and neuroprotective actions of estrogen: basic mechanisms and clinical implications
10.1016/j.steroids.2007.02.003 · 2007 · External reference
Neuroprotective effects of estrogens: potential mechanisms of action
10.1016/s0736-5748(00)00017-4 · 2000 · External reference
Estrogen effects on the hippocampus and frontal lobes
2005 · External reference
Estrogen-induced plasticity from cells to circuits: predictions for cognitive function
10.1016/j.tips.2008.12.006 · 2009 · External reference
Lifelong estrogen exposure and cognitive performance in elderly women
10.1006/brcg.1999.1078 · 1999 · External reference
Reproductive factors and the risk of incident dementia: a cohort study of UK Biobank participants
10.1371/journal.pmed.1003955 · 2022 · External reference
Associations between reproductive history, hormone use, APOE ε4 genotype and cognition in middle- to older-aged women from the UK Biobank
10.3389/fnagi.2022.1014605 · 2023 · External reference
Life long endogenous estrogen exposure and later adulthood cognitive function in a population of naturally postmenopausal women from Southern China: the Guangzhou Biobank Cohort Study
10.1016/j.psyneuen.2010.11.009 · 2011 · External reference
Effect of reproductive history and exogenous hormone use on cognitive function in mid- and late life
10.1111/jgs.14658 · 2016 · External reference
Reproductive history and risk of cognitive impairment in elderly women: a cross-sectional study in eastern China
10.3233/jad-150444 · 2015 · External reference
Reproductive and hormonal factors and risk of cognitive impairment among Singapore Chinese women
10.1016/j.ajog.2020.02.032 · 2020 · External reference
Female reproductive factors and risk of mild cognitive impairment and dementia: the HUNT Study
10.14283/jpad.2024.46 · 2024 · External reference
Reproductive period duration and cognitive function in postmenopausal Latina women in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
10.1016/j.maturitas.2023.04.270 · 2023 · External reference
Reproductive period and dementia: a 44-year longitudinal population study of Swedish women
10.1002/alz.12118 · 2020 · External reference
Reproductive period, endogenous estrogen exposure and dementia incidence among women in Latin America and China; a 10/66 population-based cohort study
10.1371/journal.pone.0192889 · 2018 · External reference
Reproductive period and cognitive function in a representative sample of naturally postmenopausal women aged 60–64 years
10.1080/13697130500345240 · 2005 · External reference
Endogenous sex hormones and cognitive function in older women
10.1016/j.jalz.2015.12.010 · 2016 · External reference
Associations of reproductive factors and exogenous estrogens with global and domain-specific cognition in later life
10.1002/alz.13394 · 2024 · External reference
Postmenopausal hormone therapy and cognitive outcomes: the Women’s Health Initiative Memory Study (WHIMS)
10.1016/j.jsbmb.2009.11.007 · 2010 · External reference
Critical window hypothesis of hormone therapy and cognition: a scientific update on clinical studies
10.1097/gme.0b013e3182960cf8 · 2013 · External reference
Hormone therapy, timing of initiation, and cognition in women aged older than 60 years: the REMEMBER pilot study
10.1097/01.gme.0000191204.38664.61 · 2006 · External reference
Hormone therapy and cognitive function
10.1093/humupd/dmp022 · 2009 · External reference
Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County study
10.1001/jama.288.17.2123 · 2002 · External reference
Postmenopausal hormone therapy, timing of initiation, APOE and cognitive decline
10.1016/j.neurobiolaging.2010.10.007 · 2012 · External reference
Timing of hormone therapy and dementia: the critical window theory revisited
10.1002/ana.22239 · 2011 · External reference
Postmenopausal hormone therapy and risk of cognitive decline in community-dwelling aging women
10.1212/01.wnl.0000132522.13574.67 · 2004 · External reference
Origin, methods, and evolution of the three nurses’ health studies
10.2105/ajph.2016.303338 · 2016 · External reference
Reproducibility and validity of self-reported menopausal status in a prospective cohort study
10.1093/aje/126.2.319 · 1987 · External reference
Bias due to misclassification in the estimation of relative risk
10.1093/oxfordjournals.aje.a112408 · 1977 · External reference
Cumulative risk of breast cancer to age 70 years according to risk factor status: data from the Nurses’ Health Study
10.1093/aje/152.10.950 · 2000 · External reference
Apolipoprotein E, cardiovascular disease and cognitive function in aging women
10.1016/j.neurobiolaging.2004.05.003 · 2005 · External reference
A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts
10.1371/journal.pone.0173997 · 2017 · External reference
The telephone interview for cognitive status
1988 · External reference
Use of brief cognitive tests to identify individuals in the community with clinically diagnosed Alzheimer’s disease
10.3109/00207459109150691 · 1991 · External reference
The Consortium to Establish a Registry for Alzheimer’s Disease (CERAD). Part V. A normative study of the neuropsychological battery
10.1212/wnl.44.4.609 · 1994 · External reference
A randomized trial of beta carotene supplementation and cognitive function in men: the Physicians’ Health Study II
10.1001/archinte.167.20.2184 · 2007 · External reference
Interaction between apolipoprotein E genotype and hypertension on cognitive function in older women in the Nurses’ Health Study
10.1371/journal.pone.0224975 · 2019 · External reference
Performance of a Five-Item Mental Health Screening Test
10.1097/00005650-199102000-00008 · 1991 · External reference
Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years
10.1136/bmj.37977.495729.ee · 2004 · External reference
Brain meets body: the blood-brain barrier as an endocrine interface
10.1210/en.2012-1435 · 2012 · External reference
Effects of long-term ovariectomy and estrogen treatment on maze learning in aged mice
10.1016/j.exger.2004.05.005 · 2004 · External reference
Cognitive effects of diphenyl diselenide and estradiol treatments in ovariectomized mice
10.1016/j.nlm.2012.10.005 · 2013 · External reference
Galanthamine plus estradiol treatment enhances cognitive performance in aged ovariectomized rats
10.1016/j.yhbeh.2011.08.010 · 2011 · External reference
Reproductive senescence predicts cognitive decline in aged female monkeys
10.1097/00001756-199705260-00048 · 1997 · External reference
Synaptic correlates of memory and menopause in the hippocampal dentate gyrus in rhesus monkeys
10.1016/j.neurobiolaging.2010.09.014 · 2012 · External reference
A “mitochondrial cascade hypothesis” for sporadic Alzheimer’s disease
10.1016/j.mehy.2003.12.045 · 2004 · External reference
The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity
10.1016/j.neurobiolaging.2015.03.013 · 2015 · External reference
Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition
10.1038/s41598-021-90084-y · 2021 · External reference
Menopause accelerates biological aging
10.1073/pnas.1604558113 · 2016 · External reference
Age at menopause, cause-specific mortality and total life expectancy
10.1097/01.ede.0000165392.35273.d4 · 2005 · External reference
Reproductive period and risk of dementia in a diverse cohort of health care members
10.1212/wnl.0000000000007326 · 2019 · External reference
Reproductive factors and cognitive impairment in natural menopausal women: a cross-sectional study
10.3389/fendo.2022.893901 · 2022 · External reference
Endogenous and exogenous hormone exposure and risk of cognitive impairment in Swedish twins: a preliminary study
10.1016/j.psyneuen.2005.01.004 · 2005 · External reference
Late menarche, not reproductive period, is associated with poor cognitive function in postmenopausal women in Taiwan
10.3390/ijerph18052345 · 2021 · External reference
Connections between reproductive health and cognitive aging among women enrolled in the HCHS/SOL and SOL-INCA
10.1002/alz.13575 · 2024 · External reference
Reproductive period and risk of dementia in postmenopausal women
10.1001/jama.285.11.1475 · 2001 · External reference
Effect of estrogen plus progestin on global cognitive function in postmenopausal women: the Women’s Health Initiative Memory Study: a Randomized Controlled Trial
10.1001/jama.289.20.2663 · 2003 · External reference
Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women: the Women’s Health Initiative Memory Study: a randomized controlled trial
10.1001/jama.289.20.2651 · 2003 · External reference
Hormone therapy use and risk of chronic disease in the Nurses’ Health Study: a comparative analysis with the women’s health initiative
10.1093/aje/kwx131 · 2017 · External reference
Systematic review and meta-analysis of the effects of menopause hormone therapy on risk of Alzheimer’s disease and dementia
10.3389/fnagi.2023.1260427 · 2023 · External reference
Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling
10.1073/pnas.1334098100 · 2003 · External reference
Estrogen plus progestin and the risk of coronary heart disease
10.1056/nejmoa030808 · External reference
Menopausal vasomotor symptoms and white matter hyperintensities in midlife women
10.1212/wnl.0000000000201401 · 2023 · External reference
Nulliparity and late menopause are associated with decreased cognitive decline
10.1176/jnp.15.2.161 · 2003 · External reference
Associations of parity with change in global cognition and incident cognitive impairment in older women
10.3389/fnagi.2022.864128 · 2022 · External reference
Oral contraceptives and cognition: a systematic review
10.1016/j.yfrne.2022.101052 · 2023 · External reference
Surgical menopause in association with cognitive function and risk of dementia: a systematic review and meta-analysis
10.1016/j.psyneuen.2019.03.013 · 2019 · External reference
Age at menopause and duration of reproductive period in association with dementia and cognitive function: a systematic review and meta-analysis
10.1016/j.psyneuen.2016.08.003 · 2016 · External reference