Research graph
References from National mortality trends due to OSA and respiratory failure in U.S adults from 1999–2023. Local targets link to admitted publications; unresolved targets remain external evidence.
Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis.
10.1016/s2213-2600(19)30198-5 · 2019 · External reference
The global burden of obstructive sleep apnea.
10.3390/diagnostics15091088 · 2025 · External reference
Rising cardiovascular mortality among obstructive sleep apnea patients: United States epidemiological trends (1999–2019).
10.1016/j.hrtlng.2025.01.005 · 2025 · External reference
Health care savings: the economic value of diagnostic and therapeutic care for obstructive sleep apnea.
10.5664/jcsm.6034 · 2016 · External reference
Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017.
10.1016/s2213-2600(20)30105-3 · 2020 · External reference
The Epidemiology of respiratory failure in the United States 2002-2017: a serial cross-sectional study.
10.1097/cce.0000000000000128 · 2020 · External reference
Trends and geographic variation in acute respiratory failure and ARDS mortality in the United States.
10.1016/j.chest.2020.10.042 · 2021 · External reference
Influence of sleep on tensor palatini EMG and upper airway resistance in normal men.
10.1152/jappl.1991.70.6.2574 · 1991 · External reference
Influences of NREM sleep on the activity of tonic vs. inspiratory phasic muscles in normal men.
10.1152/jappl.1992.73.3.1058 · 1992 · External reference
The role of obstructive sleep apnea in hypercapnic respiratory failure identified in critical care, inpatient, and outpatient settings.
10.1016/j.jsmc.2024.02.012 · 2024 · External reference
The pathophysiology of respiratory failure: control of breathing.
10.1159/000494063 · 2019 · External reference
Sleep in chronic respiratory disease: COPD and hypoventilation disorders.
10.1183/16000617.0064-2019 · 2019 · External reference
Rising U.S. mortality associated with coexisting obstructive sleep apnea and obesity, 1999-2019.
10.1016/j.sleep.2026.108783 · 2026 · External reference
Incidence and outcomes of patients hospitalized with COPD exacerbation with and without pneumonia.
10.2147/copd.s96179 · 2016 · External reference
408 Validation of claim based algorithms for sleep apnea using ICD codes.
10.1093/sleep/zsab072.407 · 2021 · External reference
The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies.
10.1016/j.jclinepi.2007.11.008 · 2008 · External reference
Rural-urban disparities: diabetes, hypertension, heart disease, and stroke mortality among black and white adults, 1999-2018.
10.1016/j.jacc.2021.01.032 · 2021 · External reference
2013 NCHS urban-rural classification scheme for counties.
2014 · External reference
Rising dementia mortality among tobacco users in the US, 2005-2020: insights from CDC-WONDER database.
2026 · External reference
Rising mortality and post-COVID shifts due to stroke in adults with dyslipidemia in the U.S. from 1999 to 2023: analysis of the CDC WONDER database.
10.1080/00207454.2026.2639360 · 2026 · External reference
The silent epidemic: cardiovascular mortality among patients with thyroid disorders-insights from CDC-WONDER database (1999-2023).
10.1177/10815589261448842 · 2026 · External reference
Age standardization of death rates: implementation of the year 2000 standard.
1998 · External reference
OSA and chronic respiratory disease: mechanisms and epidemiology.
10.3390/ijerph19095473 · 2022 · External reference
How important is obesity as a risk factor for respiratory failure, intensive care admission and death in hospitalised COVID-19 patients? Results from a single Italian centre.
10.1530/eje-20-0541 · 2020 · External reference
Respiratory disorders and their association with clinical outcomes in COVID-19: a narrative review of current literature.
10.21037/apm-22-1427 · 2023 · External reference
Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American academy of sleep medicine clinical practice guideline.
10.5664/jcsm.6506 · 2017 · External reference
The overlap syndrome of obstructive sleep apnea and chronic obstructive pulmonary disease: a systematic review.
10.3390/biomedicines11010016 · 2022 · External reference
Trends in CPAP adherence over twenty years of data collection: a flattened curve.
10.1186/s40463-016-0156-0 · 2016 · External reference
Association between obstructive sleep apnea (OSA) and COVID-19 severity.
10.1111/jsr.14260 · 2025 · External reference
Deaths: final data for 2021.
2024 · External reference
Sex differences in obstructive sleep apnoea.
10.1183/16000617.0030-2019 · 2019 · External reference
Gender differences in obstructive sleep apnea and treatment implications.
10.1016/j.smrv.2007.11.003 · 2008 · External reference
Sex differences in sleep and sleep-disordered breathing.
10.1097/mcp.0000000000001116 · 2024 · External reference
Sex-related differences in mortality, acute kidney injury, and respiratory failure among critically ill patients with COVID-19.
10.1097/md.0000000000028302 · 2021 · External reference
Association between occupational exposure and lung function, respiratory symptoms, and high-resolution computed tomography imaging in COPDGene.
10.1164/rccm.201403-0493oc · 2014 · External reference
Racial/ethnic disparities in sleep health and potential interventions among women in the United States.
10.1089/jwh.2020.8329 · 2020 · External reference
Racial disparity in obstructive sleep apnea care and its impact on cardiovascular health.
10.1007/s40675-024-00308-6 · 2024 · External reference
Prevalence and correlates of obstructive sleep apnea among African Americans: the Jackson Heart Sleep Study.
10.1093/sleep/zsy154 · 2018 · External reference
The association of age, insomnia, and self-efficacy with continuous positive airway pressure adherence in black, white, and Hispanic U.S. Veterans.
10.5664/jcsm.2988 · 2013 · External reference
Racial disparities in obstructive sleep apnea care in the United States.
10.1093/sleep/zsaf078 · 2025 · External reference
Racial differences in mortality from severe acute respiratory failure in the United States, 2008-2012.
10.1513/annalsats.201605-359oc · 2016 · External reference
Significant impacts of the COVID-19 pandemic on race/ethnic differences in US mortality.
10.1073/pnas.2205813119 · 2022 · External reference
Disparities among patients with respiratory failure.
2023 · External reference
Racial disparity in sleep apnea-related mortality in the United States.
10.1016/j.sleep.2021.11.014 · 2022 · External reference
Smoking histories by state in the U.S.
10.1016/j.amepre.2022.08.018 · 2023 · External reference
Tobacco product use among adults - United States, 2021.
10.15585/mmwr.mm7218a1 · 2023 · External reference
Rural-urban disparity in mortality in the US from 1999 to 2019.
10.1001/jama.2021.5334 · 2021 · External reference
Trends in rural and urban cigarette smoking quit ratios in the US From 2010 to 2020.
10.1001/jamanetworkopen.2022.25326 · 2022 · External reference
The burden of obesity in the rural adult population of America.
2021 · External reference
Occupational exposure to vapor-gas, dust, and fumes in a cohort of rural adults in iowa compared with a cohort of urban adults.
10.15585/mmwr.ss6621a1 · 2017 · External reference
First steps toward implementing primary care obstructive sleep apnea management in rural West Virginia.
10.1513/annalsats.202505-496ed · 2025 · External reference
Veterans Health Administration TeleSleep enterprise-wide initiative 2017–2020: bringing sleep care to our nation’s veterans.
10.5664/jcsm.10488 · 2023 · External reference
The epidemiology of mechanical ventilation use in the United States.
10.1097/ccm.0b013e3181ef4460 · 2010 · External reference
Sleep apnea and sudden cardiac death.
10.1253/circrep.cr-19-0085 · 2019 · External reference
Hematological biomarkers of the obstructive sleep apnea syndrome: a machine learning-based diagnostic and prognostic model.
10.3390/jcm14238437 · 2025 · External reference
Rural-urban disparity in mortality in the US from 1999 to 2019.
10.1001/jama.2021.5334 · ExternalCitation · doi-reference
Trends in rural and urban cigarette smoking quit ratios in the US From 2010 to 2020.
10.1001/jamanetworkopen.2022.25326 · ExternalCitation · doi-reference
Racial disparity in obstructive sleep apnea care and its impact on cardiovascular health.
10.1007/s40675-024-00308-6 · ExternalCitation · doi-reference
Smoking histories by state in the U.S.
10.1016/j.amepre.2022.08.018 · ExternalCitation · doi-reference
Trends and geographic variation in acute respiratory failure and ARDS mortality in the United States.
10.1016/j.chest.2020.10.042 · ExternalCitation · doi-reference
Rising cardiovascular mortality among obstructive sleep apnea patients: United States epidemiological trends (1999–2019).
10.1016/j.hrtlng.2025.01.005 · ExternalCitation · doi-reference
Rural-urban disparities: diabetes, hypertension, heart disease, and stroke mortality among black and white adults, 1999-2018.
10.1016/j.jacc.2021.01.032 · ExternalCitation · doi-reference
The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies.
10.1016/j.jclinepi.2007.11.008 · ExternalCitation · doi-reference
The role of obstructive sleep apnea in hypercapnic respiratory failure identified in critical care, inpatient, and outpatient settings.
10.1016/j.jsmc.2024.02.012 · ExternalCitation · doi-reference
Racial disparity in sleep apnea-related mortality in the United States.
10.1016/j.sleep.2021.11.014 · ExternalCitation · doi-reference
Rising U.S. mortality associated with coexisting obstructive sleep apnea and obesity, 1999-2019.
10.1016/j.sleep.2026.108783 · ExternalCitation · doi-reference
Gender differences in obstructive sleep apnea and treatment implications.
10.1016/j.smrv.2007.11.003 · ExternalCitation · doi-reference
Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis.
10.1016/s2213-2600(19)30198-5 · ExternalCitation · doi-reference
Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017.
10.1016/s2213-2600(20)30105-3 · ExternalCitation · doi-reference
Significant impacts of the COVID-19 pandemic on race/ethnic differences in US mortality.
10.1073/pnas.2205813119 · ExternalCitation · doi-reference
Rising mortality and post-COVID shifts due to stroke in adults with dyslipidemia in the U.S. from 1999 to 2023: analysis of the CDC WONDER database.
10.1080/00207454.2026.2639360 · ExternalCitation · doi-reference
Racial/ethnic disparities in sleep health and potential interventions among women in the United States.
10.1089/jwh.2020.8329 · ExternalCitation · doi-reference
408 Validation of claim based algorithms for sleep apnea using ICD codes.
10.1093/sleep/zsab072.407 · ExternalCitation · doi-reference
Racial disparities in obstructive sleep apnea care in the United States.
10.1093/sleep/zsaf078 · ExternalCitation · doi-reference
Prevalence and correlates of obstructive sleep apnea among African Americans: the Jackson Heart Sleep Study.
10.1093/sleep/zsy154 · ExternalCitation · doi-reference
The Epidemiology of respiratory failure in the United States 2002-2017: a serial cross-sectional study.
10.1097/cce.0000000000000128 · ExternalCitation · doi-reference
The epidemiology of mechanical ventilation use in the United States.
10.1097/ccm.0b013e3181ef4460 · ExternalCitation · doi-reference
Sex differences in sleep and sleep-disordered breathing.
10.1097/mcp.0000000000001116 · ExternalCitation · doi-reference
Sex-related differences in mortality, acute kidney injury, and respiratory failure among critically ill patients with COVID-19.
10.1097/md.0000000000028302 · ExternalCitation · doi-reference
Association between obstructive sleep apnea (OSA) and COVID-19 severity.
10.1111/jsr.14260 · ExternalCitation · doi-reference
Influence of sleep on tensor palatini EMG and upper airway resistance in normal men.
10.1152/jappl.1991.70.6.2574 · ExternalCitation · doi-reference
Influences of NREM sleep on the activity of tonic vs. inspiratory phasic muscles in normal men.
10.1152/jappl.1992.73.3.1058 · ExternalCitation · doi-reference
The pathophysiology of respiratory failure: control of breathing.
10.1159/000494063 · ExternalCitation · doi-reference
Association between occupational exposure and lung function, respiratory symptoms, and high-resolution computed tomography imaging in COPDGene.
10.1164/rccm.201403-0493oc · ExternalCitation · doi-reference
The silent epidemic: cardiovascular mortality among patients with thyroid disorders-insights from CDC-WONDER database (1999-2023).
10.1177/10815589261448842 · ExternalCitation · doi-reference
Sex differences in obstructive sleep apnoea.
10.1183/16000617.0030-2019 · ExternalCitation · doi-reference
Sleep in chronic respiratory disease: COPD and hypoventilation disorders.
10.1183/16000617.0064-2019 · ExternalCitation · doi-reference
Trends in CPAP adherence over twenty years of data collection: a flattened curve.
10.1186/s40463-016-0156-0 · ExternalCitation · doi-reference
Sleep apnea and sudden cardiac death.
10.1253/circrep.cr-19-0085 · ExternalCitation · doi-reference
Racial differences in mortality from severe acute respiratory failure in the United States, 2008-2012.
10.1513/annalsats.201605-359oc · ExternalCitation · doi-reference
First steps toward implementing primary care obstructive sleep apnea management in rural West Virginia.
10.1513/annalsats.202505-496ed · ExternalCitation · doi-reference
How important is obesity as a risk factor for respiratory failure, intensive care admission and death in hospitalised COVID-19 patients? Results from a single Italian centre.
10.1530/eje-20-0541 · ExternalCitation · doi-reference
Tobacco product use among adults - United States, 2021.
10.15585/mmwr.mm7218a1 · ExternalCitation · doi-reference
Occupational exposure to vapor-gas, dust, and fumes in a cohort of rural adults in iowa compared with a cohort of urban adults.
10.15585/mmwr.ss6621a1 · ExternalCitation · doi-reference
Respiratory disorders and their association with clinical outcomes in COVID-19: a narrative review of current literature.
10.21037/apm-22-1427 · ExternalCitation · doi-reference
Incidence and outcomes of patients hospitalized with COPD exacerbation with and without pneumonia.
10.2147/copd.s96179 · ExternalCitation · doi-reference
The overlap syndrome of obstructive sleep apnea and chronic obstructive pulmonary disease: a systematic review.
10.3390/biomedicines11010016 · ExternalCitation · doi-reference
The global burden of obstructive sleep apnea.
10.3390/diagnostics15091088 · ExternalCitation · doi-reference
OSA and chronic respiratory disease: mechanisms and epidemiology.
10.3390/ijerph19095473 · ExternalCitation · doi-reference
Hematological biomarkers of the obstructive sleep apnea syndrome: a machine learning-based diagnostic and prognostic model.
10.3390/jcm14238437 · ExternalCitation · doi-reference
Veterans Health Administration TeleSleep enterprise-wide initiative 2017–2020: bringing sleep care to our nation’s veterans.
10.5664/jcsm.10488 · ExternalCitation · doi-reference
The association of age, insomnia, and self-efficacy with continuous positive airway pressure adherence in black, white, and Hispanic U.S. Veterans.
10.5664/jcsm.2988 · ExternalCitation · doi-reference
Health care savings: the economic value of diagnostic and therapeutic care for obstructive sleep apnea.
10.5664/jcsm.6034 · ExternalCitation · doi-reference
Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American academy of sleep medicine clinical practice guideline.
10.5664/jcsm.6506 · ExternalCitation · doi-reference
