Research graph
References from Evaluating potential risk factors linked to endometriosis. Local targets link to admitted publications; unresolved targets remain external evidence.
Endometriosis: pathogenesis and treatment.
10.1038/nrendo.2013.255 · 2014 · External reference
Endometriosis is a chronic systemic disease: clinical challenges and novel innovations.
10.1016/s0140-6736(21)00389-5 · 2021 · External reference
Endometriosis: a review.
10.1001/jama.2025.2975 · 2025 · External reference
Oxidative stress and endometriosis.
10.1093/humrep/dei001 · 2005 · External reference
Risk for and consequences of endometriosis: a critical epidemiologic review.
10.1016/j.bpobgyn.2018.06.001 · 2018 · External reference
The association between exposure to multiple toxic metals and the risk of endometriosis: evidence from the results of blood and follicular fluid.
10.1016/j.scitotenv.2022.158882 · 2023 · External reference
Early-life factors and endometriosis risk.
10.1016/j.fertnstert.2015.06.040 · 2015 · External reference
Leukocyte telomere length is associated with increased risk of endometriosis: a bidirectional two-sample Mendelian randomization study.
10.3389/fendo.2023.1272200 · 2023 · External reference
Obesity and risk of female reproductive conditions: a Mendelian randomisation study.
10.1371/journal.pmed.1003679 · 2022 · External reference
Circulating inflammatory cytokines and female reproductive diseases: a mendelian randomization analysis.
10.1210/clinem/dgad376 · 2023 · External reference
Causal effects of gut microbiome on endometriosis: a two-sample mendelian randomization study.
10.1186/s12905-023-02742-0 · 2023 · External reference
Association between gut microbiota and endometriosis: a two-sample Mendelian randomization study.
10.3389/fmicb.2023.1188458 · 2023 · External reference
Separating the direct effects of traits on atherosclerotic cardiovascular disease from those mediated by type 2 diabetes.
10.1007/s00125-022-05653-1 · 2022 · External reference
The MR-Base platform supports systematic causal inference across the human phenome.
10.7554/elife.34408 · 2018 · External reference
Avoiding bias from weak instruments in Mendelian randomization studies.
10.1093/ije/dyr036 · 2011 · External reference
Assessing causal associations of hyperparathyroidism with blood counts and biochemical indicators: a Mendelian randomization study.
10.3389/fendo.2023.1295040 · 2023 · External reference
Exploring the causal relationships between type 2 diabetes and neurological disorders using a Mendelian randomization strategy.
10.1097/md.0000000000040412 · 2024 · External reference
Causal associations between HbA1c and multiple diseases unveiled through a Mendelian randomization phenome-wide association study in East Asian populations.
10.1097/md.0000000000041861 · 2025 · External reference
Assessment of potential risk factors associated with gestational diabetes mellitus: evidence from a Mendelian randomization study.
10.3389/fendo.2023.1276836 · 2023 · External reference
Assessing causal associations of bile acids with obesity indicators: a Mendelian randomization study.
10.1097/md.0000000000038610 · 2024 · External reference
Peripheral blood leukocyte telomere length and endometriosis.
10.1007/s43032-020-00214-6 · 2020 · External reference
Endometriosis and uterine fibroids and their associations with elevated C-reactive protein and leukocyte telomere length among a representative sample of U.S. women: data from the national health and nutrition examination survey, 1999-2002.
10.1089/jwh.2021.0044 · 2022 · External reference
Endometriosis is associated with aberrant endometrial expression of telomerase and increased telomere length.
10.1093/humrep/den172 · 2008 · External reference
Telomeres and telomerase in the control of stem cells.
10.3390/biomedicines10102335 · 2022 · External reference
UFMylation of MRE11 is essential for telomere length maintenance and hematopoietic stem cell survival.
10.1126/sciadv.abc7371 · 2021 · External reference
Serum paraoxonase-1 activity in women with endometriosis and its relationship with the stage of the disease.
10.1093/humrep/dem340 · 2008 · External reference
Association of dyslipidemia with endometriosis: a case control study.
2023 · External reference
Unfavorable lipid profile in women with endometriosis.
10.1016/j.fertnstert.2009.08.043 · 2010 · External reference
Elevated serum lipoprotein(a) levels in young women with endometriosis.
10.1016/s0026-0495(97)90115-3 · 1997 · External reference
Correlations between endometriosis, lipid profile, and estrogen levels.
10.1097/md.0000000000034348 · 2023 · External reference
Cell cycle, apoptosis, cell differentiation, and lipid metabolism gene expression in endometriotic tissue and exposure to parabens and benzophenones.
10.1016/j.scitotenv.2023.163014 · 2023 · External reference
Increased ApoE expression in follicular fluid and the ApoE genotype are associated with endometriosis in Chinese women.
10.3389/fendo.2021.779183 · 2021 · External reference
Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.
10.1038/s41588-018-0151-7 · 2018 · External reference
Epidemiologic and genetic associations of endometriosis with depression, anxiety, and eating disorders.
10.1001/jamanetworkopen.2022.51214 · 2023 · External reference
Dissecting the mediating and moderating effects of depression on the associations between traits and coronary artery disease: a two-step Mendelian randomization and phenome-wide interaction study.
10.1016/j.ijchp.2023.100394 · 2023 · External reference
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
10.1038/s41588-018-0309-3 · 2019 · External reference
Metabolomic profiling and biochemical evaluation of the follicular fluid of endometriosis patients.
10.1039/c7mb00181a · 2017 · External reference
Effects of dysregulated glucose metabolism on the occurrence and ART outcome of endometriosis.
10.1186/s40001-023-01280-7 · 2023 · External reference
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis.
10.1038/s41419-022-05241-6 · 2022 · External reference
Deep quantitative proteomics reveals extensive metabolic reprogramming and cancer-like changes of ectopic endometriotic stromal cells.
10.1021/acs.jproteome.5b00965 · 2016 · External reference
Repurposing dichloroacetate for the treatment of women with endometriosis.
10.1073/pnas.1916144116 · 2019 · External reference
Walking pace and the risk of stroke: a meta-analysis of prospective cohort studies.
10.1016/j.jshs.2019.09.005 · 2020 · External reference
Objectively measured physical capability levels and mortality: systematic review and meta-analysis.
10.1136/bmj.c4467 · 2010 · External reference
Markers of inflammation and their association with muscle strength and mass: a systematic review and meta-analysis.
10.1016/j.arr.2020.101185 · 2020 · External reference
Human cystatin C monomer, dimer, oligomer, and amyloid structures are related to health and disease.
10.1002/1873-3468.12463 · 2016 · External reference
Cystatin C and cardiovascular risk.
10.1373/clinchem.2009.128397 · 2009 · External reference
Cystatin C and cardiovascular or all-cause mortality risk in the general population: a meta-analysis.
10.1016/j.cca.2015.07.016 · 2015 · External reference
The potential of cystatin C as a predictive biomarker in breast cancer.
10.1080/14737140.2020.1829481 · 2020 · External reference
Role of cystatin C in urogenital malignancy.
10.3389/fendo.2022.1082871 · 2022 · External reference
Role of cystatin C levels as an inflammatory marker in predicting endometriosis.
10.1590/1806-9282.20230613 · 2023 · External reference
Cathepsin protease inhibition reduces endometriosis lesion establishment.
10.1177/1933719115611752 · 2016 · External reference
Phosphate toxicity: new insights into an old problem.
10.1042/cs20100377 · 2011 · External reference
Association between serum phosphate and in-hospital mortality of patients with AECOPD: a retrospective analysis on eICU database.
10.1016/j.heliyon.2023.e19748 · 2023 · External reference
Phosphate burden and inflammation.
10.1007/978-3-030-91623-7_2 · 2022 · External reference
The regulation of FGF23 under physiological and pathophysiological conditions.
10.1007/s00424-022-02668-w · 2022 · External reference
Estrogen downregulates the proximal tubule type IIa sodium phosphate cotransporter causing phosphate wasting and hypophosphatemia.
10.1038/ki.2008.33 · 2008 · External reference
Estrogen directly and specifically downregulates NaPi-IIa through the activation of both estrogen receptor isoforms (ERα and ERβ) in rat kidney proximal tubule.
10.1152/ajprenal.00386.2014 · 2015 · External reference
Is intracrinology of endometriosis relevant in clinical practice? A systematic review on estrogen metabolism.
10.3389/fendo.2022.950866 · 2022 · External reference
Anemia of chronic diseases: wider diagnostics-better treatment?
10.3390/nu12061784 · 2020 · External reference
The nexus of iron, senescence, and fibrosis in endometriosis: a narrative review.
10.1007/s43032-025-01999-0 · 2025 · External reference
Potential involvement of iron in the pathogenesis of peritoneal endometriosis.
10.1093/molehr/gan033 · 2008 · External reference
Disrupted iron metabolism in peritoneal fluid may induce oxidative stress in the peritoneal cavity of women with endometriosis.
10.26444/aaem/75802 · 2018 · External reference
Neural contributions to reduced fluid intelligence across the adult lifespan.
10.1523/jneurosci.0148-22.2022 · 2023 · External reference
Autonomic nervous system and inflammation interaction in endometriosis-associated pain.
10.1186/s12974-020-01752-1 · 2020 · External reference
Endometriosis: a review.
10.1001/jama.2025.2975 · ExternalCitation · doi-reference
Epidemiologic and genetic associations of endometriosis with depression, anxiety, and eating disorders.
10.1001/jamanetworkopen.2022.51214 · ExternalCitation · doi-reference
Human cystatin C monomer, dimer, oligomer, and amyloid structures are related to health and disease.
10.1002/1873-3468.12463 · ExternalCitation · doi-reference
Phosphate burden and inflammation.
10.1007/978-3-030-91623-7_2 · ExternalCitation · doi-reference
Separating the direct effects of traits on atherosclerotic cardiovascular disease from those mediated by type 2 diabetes.
10.1007/s00125-022-05653-1 · ExternalCitation · doi-reference
The regulation of FGF23 under physiological and pathophysiological conditions.
10.1007/s00424-022-02668-w · ExternalCitation · doi-reference
Peripheral blood leukocyte telomere length and endometriosis.
10.1007/s43032-020-00214-6 · ExternalCitation · doi-reference
The nexus of iron, senescence, and fibrosis in endometriosis: a narrative review.
10.1007/s43032-025-01999-0 · ExternalCitation · doi-reference
Markers of inflammation and their association with muscle strength and mass: a systematic review and meta-analysis.
10.1016/j.arr.2020.101185 · ExternalCitation · doi-reference
Risk for and consequences of endometriosis: a critical epidemiologic review.
10.1016/j.bpobgyn.2018.06.001 · ExternalCitation · doi-reference
Cystatin C and cardiovascular or all-cause mortality risk in the general population: a meta-analysis.
10.1016/j.cca.2015.07.016 · ExternalCitation · doi-reference
Unfavorable lipid profile in women with endometriosis.
10.1016/j.fertnstert.2009.08.043 · ExternalCitation · doi-reference
Early-life factors and endometriosis risk.
10.1016/j.fertnstert.2015.06.040 · ExternalCitation · doi-reference
Association between serum phosphate and in-hospital mortality of patients with AECOPD: a retrospective analysis on eICU database.
10.1016/j.heliyon.2023.e19748 · ExternalCitation · doi-reference
Dissecting the mediating and moderating effects of depression on the associations between traits and coronary artery disease: a two-step Mendelian randomization and phenome-wide interaction study.
10.1016/j.ijchp.2023.100394 · ExternalCitation · doi-reference
Walking pace and the risk of stroke: a meta-analysis of prospective cohort studies.
10.1016/j.jshs.2019.09.005 · ExternalCitation · doi-reference
The association between exposure to multiple toxic metals and the risk of endometriosis: evidence from the results of blood and follicular fluid.
10.1016/j.scitotenv.2022.158882 · ExternalCitation · doi-reference
Cell cycle, apoptosis, cell differentiation, and lipid metabolism gene expression in endometriotic tissue and exposure to parabens and benzophenones.
10.1016/j.scitotenv.2023.163014 · ExternalCitation · doi-reference
Elevated serum lipoprotein(a) levels in young women with endometriosis.
10.1016/s0026-0495(97)90115-3 · ExternalCitation · doi-reference
Endometriosis is a chronic systemic disease: clinical challenges and novel innovations.
10.1016/s0140-6736(21)00389-5 · ExternalCitation · doi-reference
Deep quantitative proteomics reveals extensive metabolic reprogramming and cancer-like changes of ectopic endometriotic stromal cells.
10.1021/acs.jproteome.5b00965 · ExternalCitation · doi-reference
Estrogen downregulates the proximal tubule type IIa sodium phosphate cotransporter causing phosphate wasting and hypophosphatemia.
10.1038/ki.2008.33 · ExternalCitation · doi-reference
Endometriosis: pathogenesis and treatment.
10.1038/nrendo.2013.255 · ExternalCitation · doi-reference
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis.
10.1038/s41419-022-05241-6 · ExternalCitation · doi-reference
Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.
10.1038/s41588-018-0151-7 · ExternalCitation · doi-reference
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
10.1038/s41588-018-0309-3 · ExternalCitation · doi-reference
Metabolomic profiling and biochemical evaluation of the follicular fluid of endometriosis patients.
10.1039/c7mb00181a · ExternalCitation · doi-reference
Phosphate toxicity: new insights into an old problem.
10.1042/cs20100377 · ExternalCitation · doi-reference
Repurposing dichloroacetate for the treatment of women with endometriosis.
10.1073/pnas.1916144116 · ExternalCitation · doi-reference
The potential of cystatin C as a predictive biomarker in breast cancer.
10.1080/14737140.2020.1829481 · ExternalCitation · doi-reference
Endometriosis and uterine fibroids and their associations with elevated C-reactive protein and leukocyte telomere length among a representative sample of U.S. women: data from the national health and nutrition examination survey, 1999-2002.
10.1089/jwh.2021.0044 · ExternalCitation · doi-reference
Oxidative stress and endometriosis.
10.1093/humrep/dei001 · ExternalCitation · doi-reference
Serum paraoxonase-1 activity in women with endometriosis and its relationship with the stage of the disease.
10.1093/humrep/dem340 · ExternalCitation · doi-reference
Endometriosis is associated with aberrant endometrial expression of telomerase and increased telomere length.
10.1093/humrep/den172 · ExternalCitation · doi-reference
Avoiding bias from weak instruments in Mendelian randomization studies.
10.1093/ije/dyr036 · ExternalCitation · doi-reference
Potential involvement of iron in the pathogenesis of peritoneal endometriosis.
10.1093/molehr/gan033 · ExternalCitation · doi-reference
Correlations between endometriosis, lipid profile, and estrogen levels.
10.1097/md.0000000000034348 · ExternalCitation · doi-reference
Assessing causal associations of bile acids with obesity indicators: a Mendelian randomization study.
10.1097/md.0000000000038610 · ExternalCitation · doi-reference
Exploring the causal relationships between type 2 diabetes and neurological disorders using a Mendelian randomization strategy.
10.1097/md.0000000000040412 · ExternalCitation · doi-reference
Causal associations between HbA1c and multiple diseases unveiled through a Mendelian randomization phenome-wide association study in East Asian populations.
10.1097/md.0000000000041861 · ExternalCitation · doi-reference
UFMylation of MRE11 is essential for telomere length maintenance and hematopoietic stem cell survival.
10.1126/sciadv.abc7371 · ExternalCitation · doi-reference
Objectively measured physical capability levels and mortality: systematic review and meta-analysis.
10.1136/bmj.c4467 · ExternalCitation · doi-reference
Estrogen directly and specifically downregulates NaPi-IIa through the activation of both estrogen receptor isoforms (ERα and ERβ) in rat kidney proximal tubule.
10.1152/ajprenal.00386.2014 · ExternalCitation · doi-reference
Cathepsin protease inhibition reduces endometriosis lesion establishment.
10.1177/1933719115611752 · ExternalCitation · doi-reference
Causal effects of gut microbiome on endometriosis: a two-sample mendelian randomization study.
10.1186/s12905-023-02742-0 · ExternalCitation · doi-reference
Autonomic nervous system and inflammation interaction in endometriosis-associated pain.
10.1186/s12974-020-01752-1 · ExternalCitation · doi-reference
Effects of dysregulated glucose metabolism on the occurrence and ART outcome of endometriosis.
10.1186/s40001-023-01280-7 · ExternalCitation · doi-reference
Circulating inflammatory cytokines and female reproductive diseases: a mendelian randomization analysis.
10.1210/clinem/dgad376 · ExternalCitation · doi-reference
Obesity and risk of female reproductive conditions: a Mendelian randomisation study.
10.1371/journal.pmed.1003679 · ExternalCitation · doi-reference
Cystatin C and cardiovascular risk.
10.1373/clinchem.2009.128397 · ExternalCitation · doi-reference
Neural contributions to reduced fluid intelligence across the adult lifespan.
10.1523/jneurosci.0148-22.2022 · ExternalCitation · doi-reference
Role of cystatin C levels as an inflammatory marker in predicting endometriosis.
10.1590/1806-9282.20230613 · ExternalCitation · doi-reference
Disrupted iron metabolism in peritoneal fluid may induce oxidative stress in the peritoneal cavity of women with endometriosis.
10.26444/aaem/75802 · ExternalCitation · doi-reference
Increased ApoE expression in follicular fluid and the ApoE genotype are associated with endometriosis in Chinese women.
10.3389/fendo.2021.779183 · ExternalCitation · doi-reference
Role of cystatin C in urogenital malignancy.
10.3389/fendo.2022.1082871 · ExternalCitation · doi-reference
Is intracrinology of endometriosis relevant in clinical practice? A systematic review on estrogen metabolism.
10.3389/fendo.2022.950866 · ExternalCitation · doi-reference
Leukocyte telomere length is associated with increased risk of endometriosis: a bidirectional two-sample Mendelian randomization study.
10.3389/fendo.2023.1272200 · ExternalCitation · doi-reference
Assessment of potential risk factors associated with gestational diabetes mellitus: evidence from a Mendelian randomization study.
10.3389/fendo.2023.1276836 · ExternalCitation · doi-reference
Assessing causal associations of hyperparathyroidism with blood counts and biochemical indicators: a Mendelian randomization study.
10.3389/fendo.2023.1295040 · ExternalCitation · doi-reference
Association between gut microbiota and endometriosis: a two-sample Mendelian randomization study.
10.3389/fmicb.2023.1188458 · ExternalCitation · doi-reference
Telomeres and telomerase in the control of stem cells.
10.3390/biomedicines10102335 · ExternalCitation · doi-reference
Anemia of chronic diseases: wider diagnostics-better treatment?
10.3390/nu12061784 · ExternalCitation · doi-reference
The MR-Base platform supports systematic causal inference across the human phenome.
10.7554/elife.34408 · ExternalCitation · doi-reference