Research graph
References from Bidirectional associations between brain functional networks and sleep disorders. Local targets link to admitted publications; unresolved targets remain external evidence.
The translational neuroscience of sleep: a contextual framework.
10.1126/science.abj8188 · 2021 · External reference
Estimation of the global prevalence and burden of insomnia: a systematic literature review-based analysis.
10.1016/j.smrv.2025.102121 · 2025 · External reference
International Classification of Sleep Disorders-Third Edition: highlights and modifications.
10.1378/chest.14-0970 · 2014 · External reference
The neurobiology, investigation, and treatment of chronic insomnia.
10.1016/s1474-4422(15)00021-6 · 2015 · External reference
Poor sleep and shift work associate with increased blood pressure and inflammation in UK Biobank participants.
10.1038/s41467-023-42758-6 · 2023 · External reference
Implications of sleep disturbance and inflammation for Alzheimer’s disease dementia.
10.1016/s1474-4422(18)30450-2 · 2019 · External reference
Habitual short sleep duration, diet, and development of type 2 diabetes in adults.
10.1001/jamanetworkopen.2024.1147 · 2024 · External reference
Sleep abnormalities in different clinical stages of psychosis: a systematic review and meta-analysis.
10.1001/jamapsychiatry.2022.4599 · 2023 · External reference
Sleep duration, brain structure, and psychiatric and cognitive problems in children.
10.1038/s41380-020-0663-2 · 2021 · External reference
Poor sleep quality is associated with increased cortical atrophy in community-dwelling adults.
10.1212/wnl.0000000000000774 · 2014 · External reference
Sleep duration and subsequent cortical thinning in cognitively normal older adults.
10.5665/sleep.5768 · 2016 · External reference
Reduced orbitofrontal and parietal gray matter in chronic insomnia: a voxel-based morphometric study.
10.1016/j.biopsych.2009.08.003 · 2010 · External reference
Hypothalamic gray matter changes in narcoleptic patients.
10.1038/nm1102-1186 · 2002 · External reference
Causal associations between sleep traits and brain structure: a bidirectional Mendelian randomization study.
10.1186/s12993-023-00220-z · 2023 · External reference
Sleep disorders causally affect the brain cortical structure: a Mendelian randomization study.
10.1016/j.sleep.2023.08.013 · 2023 · External reference
Sleep traits causally affect the brain cortical structure: a Mendelian randomization study.
10.3390/biomedicines11082296 · 2023 · External reference
Mendelian randomization analyses reveal causal relationships between brain functional networks and risk of psychiatric disorders.
10.1038/s41562-024-01879-8 · 2024 · External reference
Functional connectome fingerprinting: identifying individuals using patterns of brain connectivity.
10.1038/nn.4135 · 2015 · External reference
Causal interactions between fronto-parietal central executive and default-mode networks in humans.
10.1073/pnas.1311772110 · 2013 · External reference
Altered functional connectivity of anterior cingulate cortex in chronic insomnia: a resting-state fMRI study.
10.1016/j.sleep.2022.11.036 · 2023 · External reference
Alterations in sympathetic and parasympathetic brain networks in obstructive sleep apnea.
10.1016/j.sleep.2020.05.038 · 2020 · External reference
Altered cerebrocerebellar functional connectivity in patients with obstructive sleep apnea and its association with cognitive function.
10.1093/sleep/zsab209 · 2022 · External reference
Altered resting-state hippocampal and caudate functional networks in patients with obstructive sleep apnea.
10.1002/brb3.994 · 2018 · External reference
Beyond sleepy: structural and functional changes of the default-mode network in idiopathic hypersomnia.
10.1093/sleep/zsz156 · 2019 · External reference
Mapping the changed hubs and corresponding functional connectivity in idiopathic restless legs syndrome.
10.1016/j.sleep.2017.12.016 · 2018 · External reference
Distinct neural responses of morningness and eveningness chronotype to homeostatic sleep pressure revealed by resting-state functional magnetic resonance imaging.
10.1111/cns.13887 · 2022 · External reference
Mendelian randomization.
10.1001/jama.2017.17219 · 2017 · External reference
A robust and efficient method for Mendelian randomization with hundreds of genetic variants.
10.1038/s41467-019-14156-4 · 2020 · External reference
Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians.
10.1136/bmj.k601 · 2018 · External reference
Common variants contribute to intrinsic human brain functional networks.
10.1038/s41588-022-01039-6 · 2022 · External reference
Recent developments in Mendelian randomization studies.
10.1007/s40471-017-0128-6 · 2017 · External reference
Tobacco-induced sleep disturbances: a systematic review and meta-analysis.
10.1016/j.smrv.2021.101544 · 2021 · External reference
Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank.
10.1038/s41467-020-14625-1 · 2020 · External reference
Sleep disturbance and psychiatric disorders: a bidirectional Mendelian randomisation study.
10.1017/s2045796021000810 · 2022 · External reference
Effects of acute stress and depression on functional connectivity between prefrontal cortex and the amygdala.
10.1038/s41380-023-02056-5 · 2023 · External reference
Alterations of resting state functional network connectivity in the brain of nicotine and alcohol users.
10.1016/j.neuroimage.2016.11.012 · 2017 · External reference
Association of body mass index and waist circumference with imaging metrics of brain integrity and functional connectivity in children aged 9 to 10 years in the US, 2016–2018.
10.1001/jamanetworkopen.2023.14193 · 2023 · External reference
LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants.
10.1093/bioinformatics/btv402 · 2015 · External reference
The MR-Base platform supports systematic causal inference across the human phenome.
10.7554/elife.34408 · 2018 · External reference
Novel susceptibility genes and biomarkers for obstructive sleep apnea: insights from genetic and inflammatory proteins.
10.1093/sleep/zsae169 · 2025 · External reference
Guidelines for performing Mendelian randomization investigations: update for summer 2023.
10.12688/wellcomeopenres.15555.1 · 2019 · External reference
Interpreting findings from Mendelian randomization using the MR-Egger method.
10.1007/s10654-017-0255-x · 2017 · External reference
Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression.
10.1093/ije/dyy265 · 2018 · External reference
Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption.
10.1093/ije/dyx102 · 2017 · External reference
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression.
10.1093/ije/dyv080 · 2015 · External reference
Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases.
10.1038/s41588-018-0099-7 · 2018 · External reference
Genetic estimates of correlation and causality between blood-based biomarkers and psychiatric disorders.
10.1126/sciadv.abj8969 · 2022 · External reference
Distinguishing genetic correlation from causation across 52 diseases and complex traits.
10.1038/s41588-018-0255-0 · 2018 · External reference
Genome-wide association studies of brain imaging phenotypes in UK Biobank.
10.1038/s41586-018-0571-7 · 2018 · External reference
Sleep apnea syndrome.
10.1056/nejm200202073460602 · 2002 · External reference
Resting-state functional connectivity changes in older adults with sleep disturbance and the role of amyloid burden.
10.1038/s41380-023-02214-9 · 2023 · External reference
Early fMRI responses to somatosensory and optogenetic stimulation reflect neural information flow.
10.1073/pnas.2023265118 · 2021 · External reference
Worldwide and regional prevalence rates of co-occurrence of insomnia and insomnia symptoms with obstructive sleep apnea: a systematic review and meta-analysis.
10.1016/j.smrv.2019.01.004 · 2019 · External reference
The default mode network in cognition: a topographical perspective.
10.1038/s41583-021-00474-4 · 2021 · External reference
Basal forebrain contributes to default mode network regulation.
10.1073/pnas.1712431115 · 2018 · External reference
Abnormal resting-state functional connectivity within the default mode network subregions in male patients with obstructive sleep apnea.
10.2147/ndt.s97449 · 2016 · External reference
Altered resting-state brain activity in obstructive sleep apnea.
10.5665/sleep.2620 · 2013 · External reference
Covariance patterns between sleep health domains and distributed intrinsic functional connectivity.
10.1038/s41467-023-42945-5 · 2023 · External reference
Default mode network disturbances in restless legs syndrome/Willis-Ekbom disease.
10.1016/j.sleep.2016.05.007 · 2016 · External reference
Sleep improvements and associations with default mode network functional connectivity following rTMS for generalized anxiety disorder.
10.1016/j.brs.2018.09.004 · 2019 · External reference
Sleep deprivation reduces default mode network connectivity and anti-correlation during rest and task performance.
10.1016/j.neuroimage.2011.08.026 · 2012 · External reference
Deficits in brain default mode network connectivity mediate the relationship between poor sleep quality and anxiety severity.
10.1093/sleep/zsad296 · 2024 · External reference
Disruption of circadian rhythm genes in obstructive sleep apnea patients-possible mechanisms involved and clinical implication.
10.3390/ijms23020709 · 2022 · External reference
Circadian rhythm sleep-wake disturbances and depression in young people: implications for prevention and early intervention.
10.1016/s2215-0366(21)00034-1 · 2021 · External reference
Towards a universal taxonomy of macro-scale functional human brain networks.
10.1007/s10548-019-00744-6 · 2019 · External reference
Large-scale brain networks and psychopathology: a unifying triple network model.
10.1016/j.tics.2011.08.003 · 2011 · External reference
Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets.
10.1164/rccm.201303-0448oc · 2013 · External reference
Stress and the brain: perceived stress mediates the impact of the superior frontal gyrus spontaneous activity on depressive symptoms in late adolescence.
10.1002/hbm.24752 · 2019 · External reference
The mediation effect of depression and alcohol use disorders on the association between post-traumatic stress disorder and obstructive sleep apnea risk in 51,149 Korean firefighters: PTSD and OSA in Korean firefighters.
10.1016/j.jad.2021.05.077 · 2021 · External reference
Association of disrupted circadian rhythmicity with mood disorders, subjective wellbeing, and cognitive function: a cross-sectional study of 91 105 participants from the UK Biobank.
10.1016/s2215-0366(18)30139-1 · 2018 · External reference
Genetically proxied diurnal preference, sleep timing, and risk of major depressive disorder.
10.1001/jamapsychiatry.2021.0959 · 2021 · External reference
The cerebellum and cognitive function: 25 years of insight from anatomy and neuroimaging.
10.1016/j.neuron.2013.10.044 · 2013 · External reference
Role of the cerebellar deep nuclei in respiratory modulation.
10.1080/147342202753203078 · 2002 · External reference
Cerebellum and nonmotor function.
10.1146/annurev.neuro.31.060407.125606 · 2009 · External reference
Enhanced functional connectome of cerebellum in chronic insomnia patients.
10.1002/brb3.3103 · 2023 · External reference
Brain function in children with obstructive sleep apnea: a resting-state fMRI study.
10.1093/sleep/zsab047 · 2021 · External reference
Mendelian randomization.
10.1001/jama.2017.17219 · ExternalCitation · doi-reference
Association of body mass index and waist circumference with imaging metrics of brain integrity and functional connectivity in children aged 9 to 10 years in the US, 2016–2018.
10.1001/jamanetworkopen.2023.14193 · ExternalCitation · doi-reference
Habitual short sleep duration, diet, and development of type 2 diabetes in adults.
10.1001/jamanetworkopen.2024.1147 · ExternalCitation · doi-reference
Genetically proxied diurnal preference, sleep timing, and risk of major depressive disorder.
10.1001/jamapsychiatry.2021.0959 · ExternalCitation · doi-reference
Sleep abnormalities in different clinical stages of psychosis: a systematic review and meta-analysis.
10.1001/jamapsychiatry.2022.4599 · ExternalCitation · doi-reference
Enhanced functional connectome of cerebellum in chronic insomnia patients.
10.1002/brb3.3103 · ExternalCitation · doi-reference
Altered resting-state hippocampal and caudate functional networks in patients with obstructive sleep apnea.
10.1002/brb3.994 · ExternalCitation · doi-reference
Stress and the brain: perceived stress mediates the impact of the superior frontal gyrus spontaneous activity on depressive symptoms in late adolescence.
10.1002/hbm.24752 · ExternalCitation · doi-reference
Towards a universal taxonomy of macro-scale functional human brain networks.
10.1007/s10548-019-00744-6 · ExternalCitation · doi-reference
Interpreting findings from Mendelian randomization using the MR-Egger method.
10.1007/s10654-017-0255-x · ExternalCitation · doi-reference
Recent developments in Mendelian randomization studies.
10.1007/s40471-017-0128-6 · ExternalCitation · doi-reference
Reduced orbitofrontal and parietal gray matter in chronic insomnia: a voxel-based morphometric study.
10.1016/j.biopsych.2009.08.003 · ExternalCitation · doi-reference
Sleep improvements and associations with default mode network functional connectivity following rTMS for generalized anxiety disorder.
10.1016/j.brs.2018.09.004 · ExternalCitation · doi-reference
The mediation effect of depression and alcohol use disorders on the association between post-traumatic stress disorder and obstructive sleep apnea risk in 51,149 Korean firefighters: PTSD and OSA in Korean firefighters.
10.1016/j.jad.2021.05.077 · ExternalCitation · doi-reference
Sleep deprivation reduces default mode network connectivity and anti-correlation during rest and task performance.
10.1016/j.neuroimage.2011.08.026 · ExternalCitation · doi-reference
Alterations of resting state functional network connectivity in the brain of nicotine and alcohol users.
10.1016/j.neuroimage.2016.11.012 · ExternalCitation · doi-reference
The cerebellum and cognitive function: 25 years of insight from anatomy and neuroimaging.
10.1016/j.neuron.2013.10.044 · ExternalCitation · doi-reference
Default mode network disturbances in restless legs syndrome/Willis-Ekbom disease.
10.1016/j.sleep.2016.05.007 · ExternalCitation · doi-reference
Mapping the changed hubs and corresponding functional connectivity in idiopathic restless legs syndrome.
10.1016/j.sleep.2017.12.016 · ExternalCitation · doi-reference
Alterations in sympathetic and parasympathetic brain networks in obstructive sleep apnea.
10.1016/j.sleep.2020.05.038 · ExternalCitation · doi-reference
Altered functional connectivity of anterior cingulate cortex in chronic insomnia: a resting-state fMRI study.
10.1016/j.sleep.2022.11.036 · ExternalCitation · doi-reference
Sleep disorders causally affect the brain cortical structure: a Mendelian randomization study.
10.1016/j.sleep.2023.08.013 · ExternalCitation · doi-reference
Worldwide and regional prevalence rates of co-occurrence of insomnia and insomnia symptoms with obstructive sleep apnea: a systematic review and meta-analysis.
10.1016/j.smrv.2019.01.004 · ExternalCitation · doi-reference
Tobacco-induced sleep disturbances: a systematic review and meta-analysis.
10.1016/j.smrv.2021.101544 · ExternalCitation · doi-reference
Estimation of the global prevalence and burden of insomnia: a systematic literature review-based analysis.
10.1016/j.smrv.2025.102121 · ExternalCitation · doi-reference
Large-scale brain networks and psychopathology: a unifying triple network model.
10.1016/j.tics.2011.08.003 · ExternalCitation · doi-reference
The neurobiology, investigation, and treatment of chronic insomnia.
10.1016/s1474-4422(15)00021-6 · ExternalCitation · doi-reference
Implications of sleep disturbance and inflammation for Alzheimer’s disease dementia.
10.1016/s1474-4422(18)30450-2 · ExternalCitation · doi-reference
Association of disrupted circadian rhythmicity with mood disorders, subjective wellbeing, and cognitive function: a cross-sectional study of 91 105 participants from the UK Biobank.
10.1016/s2215-0366(18)30139-1 · ExternalCitation · doi-reference
Circadian rhythm sleep-wake disturbances and depression in young people: implications for prevention and early intervention.
10.1016/s2215-0366(21)00034-1 · ExternalCitation · doi-reference
Sleep disturbance and psychiatric disorders: a bidirectional Mendelian randomisation study.
10.1017/s2045796021000810 · ExternalCitation · doi-reference
Hypothalamic gray matter changes in narcoleptic patients.
10.1038/nm1102-1186 · ExternalCitation · doi-reference
Functional connectome fingerprinting: identifying individuals using patterns of brain connectivity.
10.1038/nn.4135 · ExternalCitation · doi-reference
Sleep duration, brain structure, and psychiatric and cognitive problems in children.
10.1038/s41380-020-0663-2 · ExternalCitation · doi-reference
Effects of acute stress and depression on functional connectivity between prefrontal cortex and the amygdala.
10.1038/s41380-023-02056-5 · ExternalCitation · doi-reference
Resting-state functional connectivity changes in older adults with sleep disturbance and the role of amyloid burden.
10.1038/s41380-023-02214-9 · ExternalCitation · doi-reference
A robust and efficient method for Mendelian randomization with hundreds of genetic variants.
10.1038/s41467-019-14156-4 · ExternalCitation · doi-reference
Insights into the aetiology of snoring from observational and genetic investigations in the UK Biobank.
10.1038/s41467-020-14625-1 · ExternalCitation · doi-reference
Poor sleep and shift work associate with increased blood pressure and inflammation in UK Biobank participants.
10.1038/s41467-023-42758-6 · ExternalCitation · doi-reference
Covariance patterns between sleep health domains and distributed intrinsic functional connectivity.
10.1038/s41467-023-42945-5 · ExternalCitation · doi-reference
Mendelian randomization analyses reveal causal relationships between brain functional networks and risk of psychiatric disorders.
10.1038/s41562-024-01879-8 · ExternalCitation · doi-reference
The default mode network in cognition: a topographical perspective.
10.1038/s41583-021-00474-4 · ExternalCitation · doi-reference
Genome-wide association studies of brain imaging phenotypes in UK Biobank.
10.1038/s41586-018-0571-7 · ExternalCitation · doi-reference
Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases.
10.1038/s41588-018-0099-7 · ExternalCitation · doi-reference
Distinguishing genetic correlation from causation across 52 diseases and complex traits.
10.1038/s41588-018-0255-0 · ExternalCitation · doi-reference
Common variants contribute to intrinsic human brain functional networks.
10.1038/s41588-022-01039-6 · ExternalCitation · doi-reference
Sleep apnea syndrome.
10.1056/nejm200202073460602 · ExternalCitation · doi-reference
Causal interactions between fronto-parietal central executive and default-mode networks in humans.
10.1073/pnas.1311772110 · ExternalCitation · doi-reference
Basal forebrain contributes to default mode network regulation.
10.1073/pnas.1712431115 · ExternalCitation · doi-reference
Early fMRI responses to somatosensory and optogenetic stimulation reflect neural information flow.
10.1073/pnas.2023265118 · ExternalCitation · doi-reference
Role of the cerebellar deep nuclei in respiratory modulation.
10.1080/147342202753203078 · ExternalCitation · doi-reference
LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants.
10.1093/bioinformatics/btv402 · ExternalCitation · doi-reference
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression.
10.1093/ije/dyv080 · ExternalCitation · doi-reference
Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption.
10.1093/ije/dyx102 · ExternalCitation · doi-reference
Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression.
10.1093/ije/dyy265 · ExternalCitation · doi-reference
Brain function in children with obstructive sleep apnea: a resting-state fMRI study.
10.1093/sleep/zsab047 · ExternalCitation · doi-reference
Altered cerebrocerebellar functional connectivity in patients with obstructive sleep apnea and its association with cognitive function.
10.1093/sleep/zsab209 · ExternalCitation · doi-reference
Deficits in brain default mode network connectivity mediate the relationship between poor sleep quality and anxiety severity.
10.1093/sleep/zsad296 · ExternalCitation · doi-reference
Novel susceptibility genes and biomarkers for obstructive sleep apnea: insights from genetic and inflammatory proteins.
10.1093/sleep/zsae169 · ExternalCitation · doi-reference
Beyond sleepy: structural and functional changes of the default-mode network in idiopathic hypersomnia.
10.1093/sleep/zsz156 · ExternalCitation · doi-reference
Distinct neural responses of morningness and eveningness chronotype to homeostatic sleep pressure revealed by resting-state functional magnetic resonance imaging.
10.1111/cns.13887 · ExternalCitation · doi-reference
Genetic estimates of correlation and causality between blood-based biomarkers and psychiatric disorders.
10.1126/sciadv.abj8969 · ExternalCitation · doi-reference
The translational neuroscience of sleep: a contextual framework.
10.1126/science.abj8188 · ExternalCitation · doi-reference
Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians.
10.1136/bmj.k601 · ExternalCitation · doi-reference
Cerebellum and nonmotor function.
10.1146/annurev.neuro.31.060407.125606 · ExternalCitation · doi-reference
Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets.
10.1164/rccm.201303-0448oc · ExternalCitation · doi-reference
Causal associations between sleep traits and brain structure: a bidirectional Mendelian randomization study.
10.1186/s12993-023-00220-z · ExternalCitation · doi-reference
Poor sleep quality is associated with increased cortical atrophy in community-dwelling adults.
10.1212/wnl.0000000000000774 · ExternalCitation · doi-reference
Guidelines for performing Mendelian randomization investigations: update for summer 2023.
10.12688/wellcomeopenres.15555.1 · ExternalCitation · doi-reference
International Classification of Sleep Disorders-Third Edition: highlights and modifications.
10.1378/chest.14-0970 · ExternalCitation · doi-reference
Abnormal resting-state functional connectivity within the default mode network subregions in male patients with obstructive sleep apnea.
10.2147/ndt.s97449 · ExternalCitation · doi-reference
Sleep traits causally affect the brain cortical structure: a Mendelian randomization study.
10.3390/biomedicines11082296 · ExternalCitation · doi-reference
Disruption of circadian rhythm genes in obstructive sleep apnea patients-possible mechanisms involved and clinical implication.
10.3390/ijms23020709 · ExternalCitation · doi-reference
Altered resting-state brain activity in obstructive sleep apnea.
10.5665/sleep.2620 · ExternalCitation · doi-reference
Sleep duration and subsequent cortical thinning in cognitively normal older adults.
10.5665/sleep.5768 · ExternalCitation · doi-reference
The MR-Base platform supports systematic causal inference across the human phenome.
10.7554/elife.34408 · ExternalCitation · doi-reference
