Research graph
References from Dynamic 99mTc-MIBI uptake and washout as functional biomarkers of glycyrrhizic acid-induced mitochondrial dysfunction and P-glycoprotein activity in HepG2 cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Public health strategies for hepatocellular carcinoma: from risk factors to prevention and control.
10.17998/jlc.2025.07.25 · 2025 · External reference
Changing treatment landscape of hepatocellular carcinoma: a real-world retrospective analysis of treatment algorithms and outcomes of patients over 10 years.
10.1007/s11523-026-01239-8 · 2026 · External reference
Toward oral nanomaterial-based drug delivery systems for hepatocellular carcinoma therapy: evidence mapping, route-specific validation, and translational challenges.
10.3389/fphar.2026.1854700 · 2026 · External reference
Glycyrrhizic acid attenuates the malignant biological properties of nonalcoholic fatty liver disease-related hepatocellular carcinoma.
10.1002/tox.24295 · 2024 · External reference
Glycyrrhizic acid enhances the anticancer activity of cisplatin in the human ovarian cancer cell line.
10.1016/j.tiv.2023.105687 · 2023 · External reference
Research progress of glycyrrhizic acid on antiviral activity.
10.2174/1389557519666190119111125 · 2019 · External reference
Glycyrrhizinic acid as an antiviral and anticancer agent in the treatment of human papillomavirus.
10.3390/jpm13121639 · 2023 · External reference
Licorice and cancer.
10.1207/s15327914nc391_1 · 2001 · External reference
Intravenous glycyrrhizin for the treatment of chronic hepatitis C: a double-blind, randomized, placebo-controlled phase I/II trial.
10.1046/j.1440-1746.1999.02008.x · 1999 · External reference
Mechanism of inhibitory effect of glycyrrhizin on replication of human immunodeficiency virus (HIV).
10.1016/0166-3542(88)90047-2 · 1988 · External reference
A prospective comparative study between 99mTc MIBI myocardial perfusion single-photon emission computed tomography and dobutamine stress echocardiography to detect viable myocardium in patients with coronary artery disease.
10.4103/ijnm.ijnm_91_22 · 2023 · External reference
Utility of (99m)Tc-Sestamibi Heart/Liver uptake ratio in screening nonalcoholic fatty liver disease during myocardial perfusion imaging.
2023 · External reference
Assessment of P-glycoprotein in patients with malignant bone and soft-tissue tumors using technetium-99m-MIBI scintigraphy.
1998 · External reference
Pgp inhibition by UIC2 antibody can be followed in vitro by using tumor-diagnostic radiotracers, 99mTc-MIBI and 18FDG.
10.1016/j.ejps.2010.09.009 · 2010 · External reference
Evaluating benign and malignant bone and soft-tissue lesions with technetium-99m-MIBI scintigraphy.
1997 · External reference
In vivo detection of multidrug-resistance-related proteins in locally advanced breast cancer using 99mTc-MIBI SPECT/CT imaging: correlation with clinical outcomes.
10.31557/apjcp.2024.25.9.3125 · 2024 · External reference
Non-invasive imaging correlates with histological and molecular characteristics of an osteosarcoma model: application for early detection and follow-up of MDR phenotype.
2007 · External reference
Glycyrrhizic acid modulates apoptosis through extrinsic/intrinsic pathways and inhibits protein kinase B- and extracellular signal-regulated kinase-mediated metastatic potential in hepatocellular carcinoma in vitro and in vivo.
10.1142/s0192415x20500123 · 2020 · External reference
Effects of glycyrrhetinic acid and liquorice extract on cell proliferation and prostate-specific antigen secretion in LNCaP prostate cancer cells.
10.1211/jpp.60.5.0013 · 2008 · External reference
Glycyrrhizic acid suppresses 1,2-dimethylhydrazine-induced colon tumorigenesis in Wistar rats: alleviation of inflammatory, proliferation, angiogenic, and apoptotic markers.
10.1002/tox.22635 · 2018 · External reference
Glycyrrhizin induces apoptosis in human stomach cancer KATO III and human promyelotic leukemia HL-60 cells.
2005 · External reference
Naturally occurring glycyrrhizin triterpene exerts anticancer effects on colorectal cancer cells via induction of apoptosis and autophagy and suppression of cell migration and invasion by targeting MMP-9 and MMP-2 expression.
2020 · External reference
Glycyrrhizic acid exerts protective effects against hypoxia/reoxygenation-induced human coronary artery endothelial cell damage by regulating mitochondria.
2020 · External reference
Antifibrotic effects of high-mobility group box 1 protein inhibitor (glycyrrhizin) on keloid fibroblasts and keloid spheroids through reduction of autophagy and induction of apoptosis.
10.3390/ijms20174134 · 2019 · External reference
Engineering of glycyrrhizin-loaded chitosan nanogel for pulmonary immunomodulation via regulation of NF-κB signaling and macrophage polarization in lung inflammation.
10.1016/j.ijbiomac.2026.152117 · 2026 · External reference
Glycyrrhizic acid inhibited inflammatory response in LPS-stimulated microglial BV2 cells via MAPK, Akt, and NF-κB signaling pathways.
10.31083/ph.2025.5532 · 2025 · External reference
Glycyrrhizic acid attenuates sorafenib resistance by inducing ferroptosis via targeting mTOR signaling in hepatocellular carcinoma.
10.1080/00365521.2024.2315317 · 2024 · External reference
Enhanced differentiation of amiodarone-induced thyrotoxicosis types using semi-quantitative 99mTc-MIBI uptake analysis: a pilot study.
10.12659/msm.945444 · 2024 · External reference
Hepatic technetium Tc 99m-labeled sestamibi elimination rate and ABCB1 (MDR1) genotype as indicators of ABCB1 (P-glycoprotein) activity in patients with cancer.
10.1016/j.clpt.2004.09.002 · 2005 · External reference
Functional imaging of multidrug resistance in breast cancer.
10.1016/s1120-1797(06)80019-0 · 2006 · External reference
99mTc-MIBI uptake as a marker of mitochondrial membrane potential in cancer cells and effects of MDR1 and verapamil.
10.1371/journal.pone.0228848 · 2020 · External reference
Spontaneous mitochondrial membrane potential change during apoptotic induction by quercetin in K562 and K562/adr cells.
10.1139/y04-113 · 2004 · External reference
