References

Application of persistent inflammation, immunosuppression, and catabolism syndrome to critically ill children: Single-center retrospective cohort, 2019-2023.

10.1097/pcc.0000000000003625 · 2025 · External reference

Persistent inflammation, immunosuppression, and catabolism: Evolution of multiple organ dysfunction.

10.1089/sur.2015.184 · 2016 · External reference

Persistent inflammation, immunosuppression and catabolism syndrome (PICS) after polytrauma: A rare syndrome with major consequences.

10.3390/jcm9010191 · 2020 · External reference

Risk factors, biomarkers, and mechanisms for persistent inflammation, immunosuppression, and catabolism syndrome (PICS): A systematic review and meta-analysis.

10.1016/j.bja.2024.03.038 · 2024 · External reference

Pediatric sepsis phenotypes and outcome: 5-Year retrospective cohort in a single center in India (2017-2022).

10.1097/pcc.0000000000003449 · 2024 · External reference

Biomarker assessment of a high-risk, data-driven pediatric sepsis phenotype characterized by persistent hypoxemia, encephalopathy, and shock.

10.1097/pcc.0000000000003499 · 2024 · External reference

Pediatric sepsis phenotype in a single-center cohort covering 2010-2020: evolution in day 1 – Day 3 trajectory and potential prognostic value.

10.1097/pcc.0000000000003708 · 2025 · External reference

Derivation and validation of pediatric sepsis-associated acute kidney injury subphenotypes with prognostic relevance.

10.1097/pcc.0000000000003789 · 2025 · External reference

Plasma linoleic acid is associated with pediatric sepsis phenotype and acute kidney injury.

10.1097/pcc.0000000000003902 · 2026 · External reference

Persistent inflammation, immunosuppression and catabolism syndrome (PICS) in critically ill children is associated with clinical outcomes: A prospective longitudinal study.

10.1111/jhn.12798 · 2021 · External reference

Clinical criteria for persistent inflammation, immunosuppression, and catabolism syndrome: An exploratory analysis of optimal cut-off values for biomarkers.

10.3390/jcm11195790 · 2022 · External reference

Pediatric persistent inflammation, immunosuppression, and catabolism syndrome prevalence in sepsis-related mortalities: A 23-year institutional history.

10.1016/j.chest.2023.05.002 · 2023 · External reference

The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies.

10.1016/s0140-6736(07)61602-x · 2007 · External reference

Early biomarker signatures in surgical sepsis.

10.1016/j.jss.2022.04.052 · 2022 · External reference

Part 14: pediatric advanced life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

2010 · External reference

Intravesical chemotherapy for maximum prophylaxis of new early phase superficial bladder carcinoma treated by transurethral resection: A combined analysis of trials by the Japanese Urological Cancer Research Group using smoothed hazard function.

10.1002/(sici)1097-0142(19991101)86:9<1818::aid-cncr25>3.0.co;2-0 · 1999 · External reference

Some diagnostic methods for Cox regression models through hazard smoothing.

10.2307/2531633 · 1990 · External reference

PRISM III: An updated Pediatric Risk of Mortality score.

10.1097/00003246-199605000-00004 · 1996 · External reference

Organ dysfunction in children with blood culture-proven sepsis: Comparative performance of four scores in a national cohort study.

10.1097/pcc.0000000000003388 · 2024 · External reference

The zonulin pathway as a potential mediator of gastrointestinal dysfunction in critical illness.

10.1097/pcc.0000000000002985 · 2022 · External reference

Multi-compartmental profiling of bacterial and host metabolites identifies intestinal dysbiosis and its functional consequences in the critically ill child.

10.1097/ccm.0000000000003841 · 2019 · External reference

Profiling gut microbiota and bile acid metabolism in critically ill children.

10.1038/s41598-022-13640-0 · 2022 · External reference

Temporal and spatial changes in the microbiome following pediatric severe traumatic brain injury.

10.1097/pcc.0000000000002929 · 2022 · External reference

Lower gastrointestinal tract dysbiosis in persistent critical illness: A systematic review.

10.1099/jmm.0.001888 · 2024 · External reference

A review of gut failure as a cause and consequence of critical illness.

10.1186/s13054-025-05309-7 · 2025 · External reference

Automated calculator for the pediatric sequential organ failure assessment score: Development and external validation in a single-center 7-year cohort, 2015-2021.

10.1097/pcc.0000000000003458 · 2024 · External reference

Dynamic prediction of mortality using longitudinally measured pediatric sequential organ failure assessment scores: A joint modeling approach.

10.1097/pcc.0000000000003457 · 2024 · External reference

Assessing bedside measures of autonomic nervous system dysregulation in the PICU.

10.1038/s41390-024-03778-0 · 2025 · External reference

Heart rate variability discriminates outcome after pediatric cardiac arrest.

10.1097/pcc.0000000000003904 · 2026 · External reference

Heart rate variability in the prediction of mortality: A systematic review and meta-analysis of healthy and patient populations.

10.1016/j.neubiorev.2022.104907 · 2022 · External reference

Heart rate variability as a marker and predictor of inflammation, nosocomial infection, and sepsis – A systematic review.

10.1016/j.autneu.2023.103116 · 2023 · External reference

Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier.

10.1172/jci149633 · 2021 · External reference

Zonulin as a biomarker and potential therapeutic target in multisystem inflammatory syndrome in children.

10.1172/jci151467 · 2021 · External reference

Regulation of intestinal permeability in health and disease: Possible therapeutic applications.

10.1016/j.arcmed.2025.103321 · 2026 · External reference