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References from TEAD4 Regulates apical domain homeostasis and cell-positioning to maintain the trophectoderm lineage during mouse blastocyst development. Local targets link to admitted publications; unresolved targets remain external evidence.
Lineage specification in the mouse preimplantation embryo
10.1242/dev.128314 · 2016 · External reference
The genetic regulation of cell fate during preimplantation mouse development
10.1016/bs.ctdb.2016.04.006 · 2016 · External reference
Common principles of early mammalian embryo self-organisation
10.1242/dev.183079 · 2020 · External reference
Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo
10.1038/nrg2564 · 2009 · External reference
Allocation of cells to inner cell mass and trophectoderm lineages in preimplantation mouse embryos
10.1016/0012-1606(82)90384-0 · 1982 · External reference
A quantitative analysis of cell allocation to trophectoderm and inner cell mass in the mouse blastocyst
10.1016/0012-1606(87)90055-8 · 1987 · External reference
Origin and formation of the first two distinct cell types of the inner cell mass in the mouse embryo
10.1073/pnas.0915063107 · 2010 · External reference
Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway
10.1016/j.devcel.2006.02.020 · 2006 · External reference
Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst
10.1016/j.ydbio.2009.04.036 · 2009 · External reference
Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst
10.1242/dev.021519 · 2008 · External reference
Asymmetric division of contractile domains couples cell positioning and fate specification
10.1038/nature18958 · 2016 · External reference
Cortical tension allocates the first inner cells of the mammalian embryo
10.1016/j.devcel.2015.07.004 · 2015 · External reference
Induction of polarity in mouse 8-cell blastomeres: specificity, geometry, and stability
10.1083/jcb.91.1.303 · 1981 · External reference
Ezrin becomes restricted to outer cells following asymmetrical division in the preimplantation mouse embryo
10.1006/dbio.1996.0186 · 1996 · External reference
Asymmetric distribution of PAR proteins in the mouse embryo begins at the 8-cell stage during compaction
10.1016/j.ydbio.2005.03.001 · 2005 · External reference
Developmental clock and mechanism of de novo polarization of the mouse embryo
10.1126/science.abd2703 · 2020 · External reference
Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo
10.1038/s41467-017-00977-8 · 2017 · External reference
Initiation of Hippo signaling is linked to polarity rather than to cell position in the pre-implantation mouse embryo
10.1242/dev.107276 · 2014 · External reference
Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo
10.1242/jcs.01666 · 2005 · External reference
Inactivation of aPKClambda reveals a context dependent allocation of cell lineages in preimplantation mouse embryos
10.1371/journal.pone.0007117 · 2009 · External reference
Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos
10.1016/j.cub.2013.05.014 · 2013 · External reference
The Hippo signaling pathway components lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass
10.1016/j.devcel.2009.02.003 · 2009 · External reference
HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst
10.1371/journal.pgen.1004618 · 2014 · External reference
Keratins are asymmetrically inherited fate determinants in the mammalian embryo
10.1038/s41586-020-2647-4 · 2020 · External reference
Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos
10.1016/j.mod.2007.11.002 · 2008 · External reference
Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development
10.1242/dev.010223 · 2007 · External reference
The first two cell-fate decisions of preimplantation mouse embryo development are not functionally independent
10.1038/srep15034 · 2015 · External reference
The first cell-fate decision of mouse preimplantation embryo development: integrating cell position and polarity
10.1098/rsob.170210 · 2017 · External reference
Cell polarity regulator PARD6B is essential for trophectoderm formation in the preimplantation mouse embryo
10.1095/biolreprod.110.084400 · 2010 · External reference
Two PAR6 proteins become asymmetrically localized during establishment of polarity in mouse oocytes
10.1016/j.cub.2004.02.061 · 2004 · External reference
Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2
10.1242/dev.038828 · 2010 · External reference
Transcription factor AP–2γ induces early Cdx2 expression and represses HIPPO signaling to specify the trophectoderm lineage
2015 · External reference
Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst
10.1242/dev.01801 · 2005 · External reference
A global double-fluorescent Cre reporter mouse
10.1002/dvg.20335 · 2007 · External reference
The apical domain is required and sufficient for the first lineage segregation in the mouse embryo
10.1016/j.devcel.2017.01.006 · 2017 · External reference
Par-aPKC-dependent and -independent mechanisms cooperatively control cell polarity, Hippo signaling, and cell positioning in 16-cell stage mouse embryos
10.1111/dgd.12235 · 2015 · External reference
Inhibition of RHO-ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst
10.1016/j.ydbio.2014.06.023 · 2014 · External reference
Rho-associated protein kinase regulates subcellular localisation of Angiomotin and Hippo-signalling during preimplantation mouse embryo development
10.1016/j.rbmo.2016.06.028 · 2016 · External reference
Asynchronous mouse embryo polarization leads to heterogeneity in cell fate specification
2025 · External reference
Transcription factor AP–2γ is a core regulator of tight junction biogenesis and cavity formation during mouse early embryogenesis
10.1242/dev.086645 · 2012 · External reference
Maternal beta-catenin and E-cadherin in mouse development
10.1242/dev.01316 · 2004 · External reference
TEAD4 regulates KRT8 and YAP in preimplantation embryos in mice but not in cattle
10.1530/rep-23-0322 · 2024 · External reference
Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment
10.1073/pnas.1201595109 · 2012 · External reference
Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst
10.1016/j.devcel.2010.02.012 · 2010 · External reference
Lineage establishment and progression within the inner cell mass of the mouse blastocyst requires FGFR1 and FGFR2
10.1016/j.devcel.2017.05.003 · 2017 · External reference
Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal
10.1101/gad.1833510 · 2010 · External reference
The transcription factor GATA6 is essential for early extraembryonic development
10.1242/dev.126.9.723 · 1999 · External reference
GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo
10.1101/gad.12.22.3579 · 1998 · External reference
TEAD4, YAP1 and WWTR1 prevent the premature onset of pluripotency prior to the 16-cell stage
10.1242/dev.179861 · 2019 · External reference
Intermediate filaments: from cell architecture to nanomechanics
10.1038/nrm2197 · 2007 · External reference
Function and regulation of Rnd proteins
10.1038/nrm1788 · 2006 · External reference
A RhoA and Rnd3 cycle regulates actin reassembly during membrane blebbing
10.1073/pnas.1600968113 · 2016 · External reference
RhoE function is regulated by ROCK I-mediated phosphorylation
10.1038/sj.emboj.7600612 · 2005 · External reference
RhoE inhibits cell cycle progression and Ras-induced transformation
10.1128/mcb.24.18.7829-7840.2004 · 2004 · External reference
Rnd proteins function as RhoA antagonists by activating p190 RhoGAP
10.1016/s0960-9822(03)00418-4 · 2003 · External reference
Type II keratins precede type I keratins during early embryonic development
10.1016/j.ejcb.2005.04.001 · 2005 · External reference
Cytokeratin filament assembly in the preimplantation mouse embryo
10.1242/dev.101.3.565 · 1987 · External reference
Disruption of the cytokeratin filament network in the preimplantation mouse embryo
10.1242/dev.104.2.219 · 1988 · External reference
Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo
10.1016/j.ydbio.2007.10.054 · 2008 · External reference
Jasplakinolide: an actin-specific reagent that promotes actin polymerization
10.1007/978-1-60761-376-3_4 · 2009 · External reference
Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo
10.7554/elife.22906 · 2017 · External reference
Angiomotin prevents pluripotent lineage differentiation in mouse embryos via Hippo pathway-dependent and -independent mechanisms
10.1038/ncomms3251 · 2013 · External reference
Membrane blebbing during apoptosis results from caspase–mediated activation of ROCK I
10.1038/35070009 · 2001 · External reference
Death for life: a path from apoptotic signaling to tissue-scale effects of apoptotic epithelial extrusion
10.1007/s00018-019-03153-x · 2019 · External reference
Epiblast formation by TEAD-YAP-dependent expression of pluripotency factors and competitive elimination of unspecified cells
10.1016/j.devcel.2019.05.024 · 2019 · External reference
Efficient generation of targeted large insertions by microinjection into two-cell-stage mouse embryos
10.1038/nbt.4166 · 2018 · External reference
E-RNAi: a web application for the multi-species design of RNAi reagents–2010 update
10.1093/nar/gkq317 · 2010 · External reference
Role of Cdx2 and cell polarity in cell allocation and specification of trophectoderm and inner cell mass in the mouse embryo
10.1101/gad.486108 · 2008 · External reference
Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis
10.1016/0092-8674(95)90373-9 · 1995 · External reference
Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint
10.1016/j.cub.2009.01.064 · 2009 · External reference
p38-MAPK-mediated translation regulation during early blastocyst development is required for primitive endoderm differentiation in mice
10.1038/s42003-021-02290-z · 2021 · External reference
Fiji: an open-source platform for biological-image analysis
10.1038/nmeth.2019 · 2012 · External reference
Unresolved reference
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Unresolved reference
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FactoMineR: an R package for multivariate analysis
10.18637/jss.v025.i01 · 2008 · External reference
10.32614/cran.package.factoextra
10.32614/cran.package.factoextra · External reference
CDC25B is required for the metaphase I-metaphase II transition in mouse oocytes
10.1242/jcs.252924 · 2022 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT method
10.1006/meth.2001.1262 · 2001 · External reference
Supplementary material from: TEAD4 Regulates apical domain homeostasis and cell-positioning to maintain the trophectoderm lineage during mouse blastocyst development
2026 · External reference