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References from Traumatic brain injury induces cell-type-specific remodelling of the proteostasis network. Local targets link to admitted publications; unresolved targets remain external evidence.
Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
10.1016/s1474-4422(18)30499-x · 2019 · External reference
Neuroimmunology of traumatic brain injury: time for a paradigm shift
10.1016/j.neuron.2017.07.010 · 2017 · External reference
Traumatic brain injury and risk of neurodegenerative disorder
10.1016/j.biopsych.2021.05.025 · 2022 · External reference
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy
10.1186/s13024-025-00842-z · 2025 · External reference
Traumatic brain injury and neurodegenerative diseases: the role of axonal injury and amyloid-β
10.1016/j.brainres.2025.149873 · 2025 · External reference
Epidemiology of mild traumatic brain injury and neurodegenerative disease
10.1016/j.mcn.2015.03.001 · 2015 · External reference
Changes in autophagy after traumatic brain injury
10.1038/sj.jcbfm.9600587 · 2008 · External reference
Synergistic effects of brain injury and aging: common mechanisms of proteostatic dysfunction
10.1016/j.tins.2021.06.003 · 2021 · External reference
Endoplasmic reticulum stress contributes to the loss of newborn hippocampal neurons after traumatic brain injury
10.1523/jneurosci.1756-17.2018 · 2018 · External reference
Inhibition of endoplasmic reticulum stress alleviates secondary injury after traumatic brain injury
10.4103/1673-5374.232477 · 2018 · External reference
Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury
10.1016/j.freeradbiomed.2008.04.038 · 2008 · External reference
Mitochondrial dysfunction early after traumatic brain injury in immature rats
10.1111/j.1471-4159.2007.04489.x · 2007 · External reference
Mitochondrial dysfunction and calcium perturbation induced by traumatic brain injury
10.1089/neu.1997.14.23 · 1997 · External reference
Expression of brain-derived neurotrophic factor, nerve growth factor, and heat shock protein HSP70 following fluid percussion brain injury in rats
10.1089/neu.1999.16.471 · 1999 · External reference
Subcellular stress response after traumatic brain injury
10.1089/neu.2006.0186 · 2007 · External reference
Patterns of heat-shock protein 70 biosynthesis following human traumatic brain injury
10.1089/neu.1998.15.411 · 1998 · External reference
Ubiquitin and ubiquitin-conjugated protein expression in the rat cerebral cortex and hippocampus following traumatic brain injury (TBI)
10.1016/j.brainres.2007.08.076 · 2007 · External reference
Pharmacological induction of the 70-kDa heat shock protein protects against brain injury
10.1016/j.neuroscience.2014.11.010 · 2015 · External reference
A comprehensive enumeration of the human proteostasis network. 1. Components of translation, protein folding, and organelle-specific systems
2022 · External reference
A comprehensive enumeration of the human proteostasis network. 2. Components of the autophagy–lysosome pathway
2023 · External reference
Single-cell expression predicts neuron-specific protein homeostasis networks
10.1098/rsob.230386 · 2024 · External reference
Proteostasis signatures in human diseases
10.1371/journal.pcbi.1013155 · 2025 · External reference
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
10.1073/pnas.0506580102 · 2005 · External reference
Prolonged activation of NF-κb following traumatic brain injury in rats
10.1089/neu.1999.16.1023 · 1999 · External reference
Activation of NF-κb mediates astrocyte swelling and brain edema in traumatic brain injury
10.1089/neu.2013.3169 · 2014 · External reference
Bioenergetic analysis of oxidative metabolism following traumatic brain injury in rats
10.1089/neu.1994.11.265 · 1994 · External reference
Comprehensive evaluation of mitochondrial redox profile, calcium dynamics, membrane integrity and apoptosis markers in a preclinical model of severe penetrating traumatic brain injury
10.1016/j.freeradbiomed.2023.02.001 · 2023 · External reference
Complement activation contributes to hypoxic-ischemic brain injury in neonatal rats
10.1523/jneurosci.23-28-09459.2003 · 2003 · External reference
Human brain trauma severity is associated with lectin complement pathway activation
10.1177/0271678x18758881 · 2019 · External reference
Coagulopathy in severe traumatic brain injury: a prospective study
10.1097/ta.0b013e318190c3c0 · 2009 · External reference
Chaperone-mediated autophagy after traumatic brain injury
10.1089/neu.2014.3694 · 2015 · External reference
Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury
10.4161/15548627.2014.981787 · 2014 · External reference
A single-cell atlas deconstructs heterogeneity across multiple models in murine traumatic brain injury and identifies novel cell-specific targets
10.1016/j.neuron.2024.06.021 · 2024 · External reference
Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
10.1016/j.celrep.2023.113395 · 2023 · External reference
A cross-disease resource of living human microglia identifies disease-enriched subsets and tool compounds recapitulating microglial states
10.1038/s41593-024-01764-7 · 2024 · External reference
N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling
10.1038/s41420-024-01913-8 · 2024 · External reference
The NEDD4-binding protein N4BP1 degrades mRNA substrates through the coding sequence independent of nonsense-mediated decay
10.1016/j.jbc.2024.107954 · 2024 · External reference
Serum GFAP and UCH-L1 for prediction of absence of intracranial injuries on head CT (ALERT-TBI): a multicentre observational study
10.1016/s1474-4422(18)30231-x · 2018 · External reference
Single cell molecular alterations reveal target cells and pathways of concussive brain injury
10.1038/s41467-018-06222-0 · 2018 · External reference
Shaping proteostasis at the cellular, tissue, and organismal level
10.1083/jcb.201612111 · 2017 · External reference
Disentangling neural cell diversity using single-cell transcriptomics
10.1038/nn.4366 · 2016 · External reference
Alpha-2-macroglobulin in inflammation, immunity and infections
10.3389/fimmu.2021.803244 · 2021 · External reference
Microglia/macrophage polarization dynamics in white matter after traumatic brain injury
10.1038/jcbfm.2013.146 · 2013 · External reference
Evolutionary conservation and divergence of the human brain transcriptome
10.1186/s13059-020-02257-z · 2021 · External reference
Dictionary learning for integrative, multimodal and scalable single-cell analysis
10.1038/s41587-023-01767-y · 2024 · External reference
Mapping identifiers for the integration of genomic datasets with the R/bioconductor package biomaRt
10.1038/nprot.2009.97 · 2009 · External reference
Clustering trees: a visualization for evaluating clusterings at multiple resolutions
10.1093/gigascience/giy083 · 2018 · External reference
Cell type hierarchy reconstruction via reconciliation of multi-resolution cluster tree
10.1093/nar/gkab481 · 2021 · External reference
Fast gene set enrichment analysis
2016 · External reference
Supplementary material from: Traumatic brain injury induces cell-type-specific remodelling of the proteostasis network
2026 · External reference
