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References from Glucagon‐Like Peptide‐1 Receptor Agonists in Pregnancy: Periconception Exposure and Perinatal Outcomes. Local targets link to admitted publications; unresolved targets remain external evidence.
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Assessing the Global Burden of Type 2 Diabetes in Women of Reproductive Age
10.1371/journal.pone.0322787 · 2025 · External reference
The Effect of Obesity on Fertility: A Systematic Review
10.1016/j.semerg.2025.102670 · 2026 · External reference
The Effect of Weight Loss Before In Vitro Fertilization on Reproductive Outcomes in Women With Obesity: A Systematic Review and Meta‐Analysis
10.7326/annals-24-01025 · 2025 · External reference
Risk of Major Congenital Malformations in Relation to Maternal Overweight and Obesity Severity: Cohort Study of 1.2 Million Singletons
10.1136/bmj.j2563 · 2017 · External reference
Periconception Glycemic Control and Congenital Anomalies in Women With Pregestational Diabetes
10.1136/bmjdrc-2020-001966 · 2021 · External reference
Fetal and Perinatal Consequences of Maternal Obesity
10.1136/adc.2009.170928 · 2011 · External reference
Effectiveness of Behavioural Weight Loss Interventions Delivered in a Primary Care Setting: A Systematic Review and Meta‐Analysis
10.1093/fampra/cmu064 · 2014 · External reference
Pregnancy After Metabolic Bariatric Surgery: Risks and Rewards for Mother and Child
10.1111/1471-0528.18032 · 2025 · External reference
Bariatric Surgery, Gestational Diabetes and Perinatal Outcomes: A Population‐Based Study
10.1111/1471-0528.70226 · 2026 · External reference
Adverse Pregnancy Outcomes Among Mothers With Hypertensive Disorders in Pregnancy: A Meta‐Analysis of Cohort Studies
10.1016/j.preghy.2021.03.001 · 2021 · External reference
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Effects of GLP‐1 Agonists and SGLT2 Inhibitors During Pregnancy and Lactation on Offspring Outcomes: A Systematic Review of the Evidence
10.3389/fendo.2023.1215356 · 2023 · External reference
Evaluation of GLP‐1 Receptor Agonists in Obstetrics and Perinatal Outcomes: A Systematic Review and Meta‐Analysis
10.1016/j.jogoh.2025.103046 · 2025 · External reference
Prescribing Trends in Glucagon‐Like Peptide‐1 Medications Among Pregnant and Postpartum Persons
10.1097/aog.0000000000006161 · 2026 · External reference
Glucagon‐Like Peptide 1 (GLP‐1) Receptor Agonists' Use During Pregnancy: Safety Data From Regulatory Clinical Trials
10.1111/dom.16437 · 2025 · External reference
Incidence of GLP‐1 Receptor Agonist Use by Women of Reproductive Age Attending General Practices in Australia, 2011‐2022: A Retrospective Open Cohort Study
10.5694/mja2.70026 · 2025 · External reference
Mechanisms of GLP‐1 Receptor Agonist‐Induced Weight Loss: A Review of Central and Peripheral Pathways in Appetite and Energy Regulation
10.1016/j.amjmed.2025.01.021 · 2025 · External reference
Gastric Inhibitory Polypeptide: The Neglected Incretin Revisited
10.1016/s0167-0115(02)00039-3 · 2002 · External reference
Glucagon‐Like Peptide‐1 7‐36: A Physiological Incretin in Man
10.1016/s0140-6736(87)91194-9 · 1987 · External reference
The Physiology of Glucagon‐Like Peptide 1
10.1152/physrev.00034.2006 · 2007 · External reference
Glucagon‐Like Peptide‐1 Cells in the Gastrointestinal Tract and Pancreas of Rat, Pig and Man
10.1111/j.1365-2362.1992.tb01464.x · 1992 · External reference
Cellular Localization of Gastric Inhibitory Polypeptide in the Duodenum and Jejunum
10.1136/gut.14.4.284 · 1973 · External reference
Mechanisms Underlying the Rapid Degradation and Elimination of the Incretin Hormones GLP‐1 and GIP
10.1016/j.beem.2009.03.005 · 2009 · External reference
GIP and GLP‐1, the Two Incretin Hormones: Similarities and Differences
10.1111/j.2040-1124.2010.00022.x · 2010 · External reference
Biological Effects and Metabolic Rates of Glucagonlike Peptide‐1 7‐36 Amide and Glucagonlike Peptide‐1 7‐37 in Healthy Subjects Are Indistinguishable
10.2337/diab.42.5.658 · 1993 · External reference
Central Administration of GLP‐1‐(7‐36) Amide Inhibits Food and Water Intake in Rats
1996 · External reference
Truncated GLP‐1 (Proglucagon 78‐107‐Amide) Inhibits Gastric and Pancreatic Functions in Man
10.1007/bf01316798 · 1993 · External reference
Effects of GLP‐1 on Gastric Emptying, Antropyloric Motility, and Transpyloric Flow in Response to a Nonnutrient Liquid
10.1023/a:1018863716749 · 1998 · External reference
Neuronal Control of Energy Homeostasis
10.1016/j.febslet.2007.11.063 · 2008 · External reference
Dipeptidyl Peptidase IV Inhibition Reduces the Degradation and Clearance of GIP and Potentiates Its Insulinotropic and Antihyperglycemic Effects in Anesthetized Pigs
10.2337/diabetes.50.7.1588 · 2001 · External reference
Secretion, Degradation, and Elimination of Glucagon‐Like Peptide 1 and Gastric Inhibitory Polypeptide in Patients With Chronic Renal Insufficiency and Healthy Control Subjects
10.2337/diabetes.53.3.654 · 2004 · External reference
Glucagon‐Like Peptide‐1 Receptor: Mechanisms and Advances in Therapy
10.1038/s41392-024-01931-z · 2024 · External reference
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Semaglutide and Cardiovascular Outcomes in Obesity Without Diabetes
10.1056/nejmoa2307563 · 2023 · External reference
Long‐Term Kidney Outcomes of Semaglutide in Obesity and Cardiovascular Disease in the SELECT Trial
10.1038/s41591-024-03015-5 · 2024 · External reference
Semaglutide in Patients With Heart Failure With Preserved Ejection Fraction and Obesity
10.1056/nejmoa2306963 · 2023 · External reference
GLP‐1 Receptor Agonists for the Reduction of Atherosclerotic Cardiovascular Risk in Patients With Type 2 Diabetes
10.1161/circulationaha.122.059595 · 2022 · External reference
The Cardiovascular Biology of Glucagon‐Like Peptide‐1
10.1016/j.cmet.2016.06.009 · 2016 · External reference
Glucagon‐Like Receptor Agonists and Next‐Generation Incretin‐Based Medications: Metabolic, Cardiovascular, and Renal Benefits
10.1016/s0140-6736(25)02105-1 · 2026 · External reference
Drug Transfer and Metabolism by the Human Placenta
10.2165/00003088-200443080-00001 · 2004 · External reference
GLP‐1‐Mediated Pregnancy and Neonatal Complications in Mice
10.3390/jdb13030029 · 2025 · External reference
Maternal GLP‐1 Receptor Activation Inhibits Fetal Growth
10.1152/ajpendo.00361.2023 · 2024 · External reference
Inflammation‐Induced Adverse Pregnancy and Neonatal Outcomes Can be Improved by the Immunomodulatory Peptide Exendin‐4
10.3389/fimmu.2018.01291 · 2018 · External reference
Long‐Term Functional Alterations Following Prenatal GLP‐1R Activation
10.1016/j.ntt.2021.106984 · 2021 · External reference
The Challenges of Obesity for Fertility: A FIGO Literature Review
10.1002/ijgo.14538 · 2023 · External reference
Obesity and Female Reproductive Health; Is There a Role for Glucagon‐Like Peptide‐1 Receptor Agonists?
10.1111/obr.70015 · 2026 · External reference
Female Obesity and Infertility
10.1016/j.bpobgyn.2014.10.014 · 2015 · External reference
Obesity, Polycystic Ovary Syndrome, and Infertility: A New Avenue for GLP‐1 Receptor Agonists
10.1210/clinem/dgaa285 · 2020 · External reference
Association Between Body Mass Index, Weight Loss and the Chance of Pregnancy in Women With Polycystic Ovary Syndrome and Overweight or Obesity: A Retrospective Cohort Study in the UK
10.1093/humrep/deac267 · 2023 · External reference
Efficacy of Exenatide on Weight Loss, Metabolic Parameters and Pregnancy in Overweight/Obese Polycystic Ovary Syndrome
10.1111/cen.13454 · 2017 · External reference
Liraglutide Increases IVF Pregnancy Rates in Obese PCOS Women With Poor Response to First‐Line Reproductive Treatments: A Pilot Randomized Study
10.1530/eje-18-0175 · 2018 · External reference
Glucagon‐Like Peptide‐1 Receptor Agonists Among Pregnancies With Pregestational Diabetes and Its Relationship With Congenital Malformations
2025 · External reference
Efficacy and Safety of Glucagon‐Like Peptide‐1 Receptor Agonist Use During the First Trimester in Pregnant Women With Type 2 Diabetes
10.1016/j.amjcard.2025.03.013 · 2025 · External reference
Safety of GLP‐1 Receptor Agonists and Other Second‐Line Antidiabetics in Early Pregnancy
10.1001/jamainternmed.2023.6663 · 2024 · External reference
Use of GLP1 Receptor Agonists in Early Pregnancy and Reproductive Safety: A Multicentre, Observational, Prospective Cohort Study Based on the Databases of Six Teratology Information Services
10.1136/bmjopen-2023-083550 · 2024 · External reference
Unintentional Periconceptional Exposure to Glucagon‐Like Peptide‐1 Receptor Agonists and Adverse Pregnancy Outcomes: A Nationwide Cohort Study in Taiwan
10.1111/dom.70334 · 2026 · External reference
Pregnancy Outcomes After Semaglutide Exposure
10.1111/bcpt.70021 · 2025 · External reference
Physiological Changes and Cardiovascular Investigations in Pregnancy
10.1016/j.hlc.2020.10.001 · 2021 · External reference
Gestational Weight Gain and Pregnancy Outcomes After GLP‐1 Receptor Agonist Discontinuation
10.1001/jama.2025.20951 · 2025 · External reference
The Safety Profile of Usage of Glucagon‐Like Peptide‐1 Receptor Agonists in Pregnancy: A Pharmacovigilance Analysis Based on the Food and Drug Administration Adverse Event Reporting System
10.1111/bcp.16354 · 2025 · External reference
Gestational Weight Gain and Hypertensive Disorders of Pregnancy With Prepregnancy and Early Pregnancy Glucagon‐Like Peptide‐1 Receptor Agonist Exposure
10.1097/aog.0000000000005995 · 2025 · External reference
Preconception Glucagon‐Like Peptide‐1 Receptor Agonist Use Associated With Decreased Risk of Adverse Obstetrical Outcomes
10.1016/j.ajog.2025.01.019 · 2025 · External reference
Periconceptional GLP‐1 Receptor Agonist Exposure and Obstetric Outcomes: A Danish Nationwide Cohort Study
10.1093/hropen/hoag015 · 2026 · External reference
10.1038/s41366‐026‐02111‐5
10.1038/s41366‐026‐02111‐5 · External reference
Prepregnancy GLP‐1RA Exposure and Risk of Hypertensive Disorders of Pregnancy Among Women With Obesity and Diabetes
10.1002/oby.70221 · 2026 · External reference
Congenital Malformation Risk According to Hemoglobin A1c Values in a Contemporary Cohort With Pregestational Diabetes
10.1055/s-0041-1730435 · 2021 · External reference
Estimating Global Burden of Disease due to Congenital Anomaly: An Analysis of European Data
10.1136/archdischild-2016-311845 · 2018 · External reference
GLP‐1 Receptor Agonist Exposure During Pregnancy: A Systematic Review and Meta‐Analysis of Adverse Pregnancy Outcomes
2026 · External reference
Pregnancy Outcomes Following First Trimester Exposure to Semaglutide
10.1177/1753495x251346330 · 2025 · External reference
Case Report: Exenatide Use During Pregnancy
10.1097/ten.0b013e3181a5875e · 2009 · External reference
Normal Pregnancy Outcome After First‐Trimester Exposure to Liraglutide in a Woman With Type 2 Diabetes
10.1111/dme.12726 · 2015 · External reference
Pregnancy Outcome and Liraglutide Levels in Serum and Umbilical Vein Blood of a Woman With Type 2 Diabetes. A Case Report
2018 · External reference
Semaglutide and Pregnancy
10.1002/ijgo.15092 · 2023 · External reference
Case Series: Exposure to Glucagon‐Like Peptide‐1 Receptor Agonist in the First Trimester of Pregnancy in Two Siblings
10.2174/0118715303252109231023115112 · 2024 · External reference
A Case Report on Use of Dulaglutide During the First Weeks of Pregnancy in Woman Affected by Type 2 Diabetes Mellitus
10.1007/s00592-022-01954-4 · 2023 · External reference
Gestational Weight Gain: Update on Outcomes and Interventions
10.1007/s11892-020-1296-1 · 2020 · External reference
Pre‐Pregnancy GLP‐1 Receptor Agonist or Tirzepatide Use and Gestational Diabetes Risk: Evaluating Pharmacodynamic Carry‐Over Versus Post‐Discontinuation Metabolic Rebound in a Multinational Federated Cohort
10.1111/dom.70853 · 2026 · External reference
Gestational Weight Gain Particularly Affects the Risk of Large for Gestational Age Infants in Non‐Obese Mothers
10.1055/a-0891-0919 · 2019 · External reference
The Impact of Gestational Weight Gain on Fetal and Neonatal Outcomes: The Araraquara Cohort Study
10.1186/s12884-024-06523-x · 2024 · External reference
Nutritional Deficiencies and Muscle Loss in Adults With Type 2 Diabetes Using GLP‐1 Receptor Agonists: A Retrospective Observational Study
10.1016/j.obpill.2025.100186 · 2025 · External reference
The Effect of Semaglutide on Intestinal Iron Absorption in Patients With Type 2 Diabetes Mellitus—A Pilot Study
10.1111/dom.16368 · 2025 · External reference
Investigating Nutrient Intake During Use of Glucagon‐Like Peptide‐1 Receptor Agonist: A Cross‐Sectional Study
10.3389/fnut.2025.1566498 · 2025 · External reference
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Pharmacologically Relevant Drug Interactions of Glucagon‐Like Peptide‐1 Receptor Agonists
10.15406/japlr.2019.08.00311 · 2019 · External reference
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Subcutaneous Semaglutide During Breastfeeding: Infant Safety Regarding Drug Transfer Into Human Milk
10.3390/nu16172886 · 2024 · External reference
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10.2139/ssrn.5387250
10.2139/ssrn.5387250 · External reference
An Overview of Links Between Obesity and Mental Health
10.1007/s13679-015-0164-9 · 2015 · External reference
Prevalence of Use and Interest in Using Glucagon‐Like Peptide‐1 Receptor Agonists for Weight Loss: A Population Study in Great Britain
10.1186/s12916-025-04528-7 · 2026 · External reference
Maternal Mental Health During Pregnancy: A Critical Review
2022 · External reference
Weight Regain After Cessation of Medication for Weight Management: Systematic Review and Meta‐Analysis
10.1136/bmj-2025-085304 · 2026 · External reference
Weight Regain and Cardiometabolic Effects After Withdrawal of Semaglutide: The STEP 1 Trial Extension
10.1111/dom.14725 · 2022 · External reference
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