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References from N 6 ‐Methyladenosine Demethylase FTO Protects Pancreatic ΒTC6 Cells From Cholesterol‐Triggered Damage by Regulating Nfatc4 : Insights From RNA ‐Seq Analysis. Local targets link to admitted publications; unresolved targets remain external evidence.
FTO Regulates Myoblast Proliferation by Controlling CCND1 Expression in an m6A‐YTHDF2‐Dependent Manner
10.1016/j.yexcr.2021.112524 · 2021 · External reference
FTO Inhibits Insulin Secretion and Promotes NF‐κB Activation Through Positively Regulating ROS Production in Pancreatic β Cells
10.1371/journal.pone.0127705 · 2015 · External reference
Cholesterol Metabolism and Pancreatic β‐Cell Function
10.1097/mol.0b013e32832ac180 · 2009 · External reference
Cholesterol Redistribution in Pancreatic β‐Cells: A Flexible Path to Regulate Insulin Secretion
10.3390/biom13020224 · 2023 · External reference
Targeting FTO Suppresses Pancreatic Carcinogenesis via Regulating Stem Cell Maintenance and EMT Pathway
10.3390/cancers14235919 · 2022 · External reference
Calcineurin/NFAT Signalling Regulates Pancreatic Beta‐Cell Growth and Function
10.1038/nature05097 · 2006 · External reference
NFATc4 Regulates Sox9 Gene Expression in Acinar Cell Plasticity and Pancreatic Cancer Initiation
10.1155/2016/5272498 · 2016 · External reference
Cholesterol Induces Inflammation and Reduces Glucose Utilization
10.1515/med-2023-0701 · 2023 · External reference
Molecular Mechanisms and Functions of Pyroptosis in Inflammation and Antitumor Immunity
10.1016/j.molcel.2021.09.003 · 2021 · External reference
Inflammation‐Related Pyroptosis, a Novel Programmed Cell Death Pathway, and Its Crosstalk With Immune Therapy in Cancer Treatment
10.7150/thno.62521 · 2021 · External reference
The Emerging Role of RNA N6‐Methyladenosine Modification in Pancreatic Cancer
10.3389/fonc.2022.927640 · 2022 · External reference
FTO Promotes Cervical Cancer Cell Proliferation, Colony Formation, Migration and Invasion via the Regulation of the BMP4/Hippo/YAP1/TAZ Pathway
10.1016/j.yexcr.2023.113585 · 2023 · External reference
The Role of m6A Modification in the Biological Functions and Diseases
10.1038/s41392-020-00450-x · 2021 · External reference
Inflammation and Wnt Signaling: Target for Immunomodulatory Therapy?
10.3389/fcell.2020.615131 · 2020 · External reference
Downregulation of NFAT3 due to Lack of T‐Box Transcription Factor TBX5 Is Crucial for Cytokine Expression in T Cells
10.4049/jimmunol.1602113 · 2018 · External reference
m6A RNA Modification and Its Emerging Roles in Diseases: Recent Advances and Therapeutic Implications
10.1186/s12967-026-07805-y · 2026 · External reference
Primers on Molecular Pathways —The NFAT Transcription Pathway in Pancreatic Cancer
10.1159/000315035 · 2010 · External reference
N(6)‐Methyladenosine (m(6)A) in Pancreatic Cancer: Regulatory Mechanisms and Future Direction
10.7150/ijbs.60115 · 2021 · External reference
Trends in Insulin Resistance: Insights Into Mechanisms and Therapeutic Strategy
10.1038/s41392-022-01073-0 · 2022 · External reference
N6‐Methyladenosine Demethylase FTO Enhances Chemo‐Resistance in Colorectal Cancer Through SIVA1‐Mediated Apoptosis
10.1016/j.ymthe.2022.10.012 · 2023 · External reference
m6A Methylation Regulates Hypoxia‐Induced Pancreatic Cancer Glycolytic Metabolism Through ALKBH5‐HDAC4‐HIF1α Positive Feedback Loop
10.1038/s41388-023-02704-8 · 2023 · External reference
ApoA‐I Protects Pancreatic β‐Cells From Cholesterol‐Induced Mitochondrial Damage and Restores Their Ability to Secrete Insulin
10.1161/atvbaha.123.319378 · 2024 · External reference
The Role of Mitogen‐Activated Protein Kinase‐Activated Protein Kinases (MAPKAPKs) in Inflammation
10.3390/genes4020101 · 2013 · External reference
Transcriptional Profiling of Hypoxic Neural Stem Cells Identifies Calcineurin‐NFATc4 Signaling as a Major Regulator of Neural Stem Cell Biology
10.1016/j.stemcr.2015.06.008 · 2015 · External reference
NFAT, Immunity and Cancer: A Transcription Factor Comes of Age
10.1038/nri2818 · 2010 · External reference
NFAT Gene Family in Inflammation and Cancer
10.2174/1566524011313040007 · 2013 · External reference
Cholesterol Metabolism, Pancreatic β‐Cell Function and Diabetes
10.1016/j.bbadis.2019.04.012 · 2019 · External reference
Detailed Resume of RNA m6A Demethylases
10.1016/j.apsb.2022.01.003 · 2022 · External reference
FTO Overexpression Inhibits Apoptosis of Hypoxia/Reoxygenation‐Treated Myocardial Cells by Regulating m6A Modification of Mhrt
10.1007/s11010-021-04069-6 · 2021 · External reference
FTO Represses NLRP3‐Mediated Pyroptosis and Alleviates Myocardial Ischemia‐Reperfusion Injury via Inhibiting CBL‐Mediated Ubiquitination and Degradation of β‐Catenin
10.1096/fj.202201793rr · 2023 · External reference
RNA N6‐Methyladenosine Demethylase FTO Promotes Pancreatic Cancer Progression by Inducing the Autocrine Activity of PDGFC in an m6A‐YTHDF2‐Dependent Manner
10.1038/s41388-022-02306-w · 2022 · External reference
The Role of the Fat Mass and Obesity‐Associated Protein in the Proliferation of Pancreatic Cancer Cells
2019 · External reference
The m6A Demethylase Fat Mass and Obesity‐Associated Protein Mitigates Pyroptosis and Inflammation in Doxorubicin‐Induced Heart Failure via the Toll‐Like Receptor 4/NF‐κB Pathway
10.21037/cdt-23-326 · 2024 · External reference
NFAT Control of Immune Function: New Frontiers for an Abiding Trooper
10.12688/f1000research.13426.1 · 2018 · External reference
The RNA m6A Methyltransferase METTL3 Promotes Pancreatic Cancer Cell Proliferation and Invasion
10.1016/j.prp.2019.152666 · 2019 · External reference
FTO Promotes Multiple Myeloma Progression by Posttranscriptional Activation of HSF1 in an m(6)A‐YTHDF2‐Dependent Manner
10.1016/j.ymthe.2021.12.012 · 2022 · External reference
Dynamic Transcriptomic m6A Decoration: Writers, Erasers, Readers and Functions in RNA Metabolism
10.1038/s41422-018-0040-8 · 2018 · External reference
Recent Knowledge of NFATc4 in Oncogenesis and Cancer Prognosis
10.1186/s12935-022-02619-6 · 2022 · External reference
Oncogenic and Tumor‐Suppressive Functions of the RNA Demethylase FTO
10.1158/0008-5472.can-21-3710 · 2022 · External reference
