Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Rethinking the Oligodendrocyte Progenitor Cell: One Cell, Many Functions. Local targets link to admitted publications; unresolved targets remain external evidence.
Cell of All Trades: Oligodendrocyte Precursor Cells in Synaptic, Vascular, and Immune Function
10.1101/gad.344218.120 · 2021 · External reference
Molecular and Spatial Signatures of Mouse Brain Ageing at Single‐Cell Resolution
10.1016/j.cell.2022.12.010 · 2023 · External reference
Oligodendrocyte Precursor Cells Engulf Synapses During Circuit Remodeling in Mice
10.1038/s41593-022-01170-x · 2022 · External reference
Motor Learning Drives Dynamic Patterns of Intermittent Myelination on Learning‐Activated Axons
10.1038/s41593-022-01169-4 · 2022 · External reference
Changes in Oligodendroglial Subpopulations in Parkinson's Disease
10.1186/s13041-023-01055-5 · 2023 · External reference
Glial Patchwork: Oligodendrocyte Progenitor Cells and Astrocytes Blanket the Central Nervous System
2022 · External reference
Transfer of Myelin‐Reactive Th17 Cells Impairs Endogenous Remyelination in the Central Nervous System of Cuprizone‐Fed Mice
10.1523/jneurosci.3817-14.2015 · 2015 · External reference
CNS Myelin Sheath Lengths Are an Intrinsic Property of Oligodendrocytes
10.1016/j.cub.2015.07.056 · 2015 · External reference
Dynamic Changes in Myelin Aberrations and Oligodendrocyte Generation in Chronic Amyloidosis in Mice and Men
10.1002/glia.22432 · 2013 · External reference
Glutamatergic Synapses on Oligodendrocyte Precursor Cells in the Hippocampus
10.1038/35012083 · 2000 · External reference
Efficient Central Nervous System Remyelination Requires T Cells
10.1002/ana.10578 · 2003 · External reference
Molecular and Functional Heterogeneity in Dorsal and Ventral Oligodendrocyte Progenitor Cells of the Mouse Forebrain in Response to DNA Damage
10.1038/s41467-022-30010-6 · 2022 · External reference
Age Changes in Myelinated Nerve Fibres of the Cingulate Bundle and Corpus Callosum in the Rhesus Monkey
10.1002/cne.22379 · 2010 · External reference
Activity‐Driven Myelin Sheath Growth Is Mediated by mGluR5
10.1038/s41593-025-01956-9 · 2025 · External reference
Emerging Roles of Oligodendrocyte Precursor Cells in Neural Circuit Development and Remodeling
10.1016/j.tins.2023.05.007 · 2023 · External reference
Oligodendrocyte Precursor Cells Ingest Axons in the Mouse Neocortex
10.1073/pnas.2202580119 · 2022 · External reference
Cellular Mechanisms of Adaptive Myelination: Bridging the Gap Between Animal Studies and Human Cognition
10.1080/17588928.2016.1206070 · 2017 · External reference
10.64898/2026.05.11.724385
10.64898/2026.05.11.724385 · External reference
Immune–Stem Cell Crosstalk in the Central Nervous System: How Oligodendrocyte Progenitor Cells Interact With Immune Cells
10.1111/imcb.12610 · 2023 · External reference
Defective Cholesterol Clearance Limits Remyelination in the Aged Central Nervous System
10.1126/science.aan4183 · 2018 · External reference
Disease‐Associated Oligodendroglia: A Putative Nexus in Neurodegeneration
10.1016/j.it.2024.08.003 · 2024 · External reference
Wnt‐Dependent Oligodendroglial‐Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury
10.1016/j.neuron.2020.09.033 · 2020 · External reference
Voltage‐Gated and Chemogenetic Modulation of Calcium Signalling in Oligodendrocyte Development and Synaptic Integration
10.1111/jnc.70259 · 2025 · External reference
Astrocytes Mediate Synapse Elimination Through MEGF10 and MERTK Pathways
10.1038/nature12776 · 2013 · External reference
Oligodendrocyte Progenitors: Adult Stem Cells of the Central Nervous System?
10.1016/j.expneurol.2014.04.027 · 2014 · External reference
Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age‐Associated Functional Decline
10.1016/j.celrep.2016.03.069 · 2016 · External reference
NG2‐Expressing Glial Progenitor Cells: An Abundant and Widespread Population of Cycling Cells in the Adult Rat CNS
10.1016/s1044-7431(03)00210-0 · 2003 · External reference
Changes in the Oligodendrocyte Progenitor Cell Proteome With Ageing
10.1074/mcp.ra120.002102 · 2020 · External reference
Early Oligodendrocyte/Myelin Pathology in Alzheimer's Disease Mice Constitutes a Novel Therapeutic Target
10.2353/ajpath.2010.100087 · 2010 · External reference
Progeny of Olig2‐Expressing Progenitors in the Gray and White Matter of the Adult Mouse Cerebral Cortex
10.1523/jneurosci.2831-08.2008 · 2008 · External reference
Diversity of Oligodendrocytes and Their Progenitors
10.1016/j.conb.2017.09.015 · 2017 · External reference
Ageing Compromises Oligodendrocyte Precursor Cell Maturation and Efficient Remyelination in the Monkey Brain
10.1007/s11357-022-00621-4 · 2023 · External reference
Regulatory T Cells Promote Myelin Regeneration in the Central Nervous System
10.1038/nn.4528 · 2017 · External reference
Adaptive Human Immunity Drives Remyelination in a Mouse Model of Demyelination
10.1093/brain/awx008 · 2017 · External reference
Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity
10.1523/jneurosci.0908-16.2016 · 2016 · External reference
Oligodendrocyte Precursor Cells Facilitate Neuronal Lysosome Release
10.1038/s41467-025-56484-8 · 2025 · External reference
The Active Contribution of OPCs to Neuroinflammation Is Mediated by LRP1
10.1007/s00401-019-02073-1 · 2020 · External reference
Adult Oligodendrocyte Progenitor Cells—Multifaceted Regulators of the CNS in Health and Disease
10.1016/j.bbi.2016.01.005 · 2016 · External reference
Proliferating Bipotential Glial Progenitor Cells in Adult Rat Optic Nerve
10.1038/319499a0 · 1986 · External reference
The Oligodendrocyte‐Type‐2 Astrocyte Cell Lineage Is Specialised for Myelination
10.1038/323335a0 · 1986 · External reference
Developmental Origin of Oligodendrocytes Determines Their Function in the Adult Brain
10.1038/s41593-024-01666-8 · 2024 · External reference
Regenerating CNS Myelin—From Mechanisms to Experimental Medicines
10.1038/nrn.2017.136 · 2017 · External reference
Neuroprotection and Repair in Multiple Sclerosis
10.1038/nrneurol.2012.200 · 2012 · External reference
Endogenous Progenitors Remyelinate Demyelinated Axons in the Adult CNS
10.1016/s0896-6273(00)80359-1 · 1997 · External reference
Neuronal Activity Promotes Oligodendrogenesis and Adaptive Myelination in the Mammalian Brain
10.1126/science.1252304 · 2014 · External reference
Aging and Senescent Fates of Oligodendrocyte Precursor Cells in the Mouse Brain
10.1038/s41514-024-00176-y · 2024 · External reference
Review: Leucocyte‐Endothelial Cell Crosstalk at the Blood–Brain Barrier: A Prerequisite for Successful Immune Cell Entry to the Brain
10.1111/j.1365-2990.2010.01140.x · 2011 · External reference
White Matter Aging and Its Impact on Brain Function
10.1016/j.neuron.2024.10.019 · 2025 · External reference
Granzyme B‐Inhibitor Serpina3n Induces Neuroprotection In Vitro and In Vivo
10.1186/s12974-015-0376-7 · 2015 · External reference
MHC Class I and MHC Class II Reporter Mice Enable Analysis of Immune Oligodendroglia in Mouse Models of Multiple Sclerosis
10.7554/elife.82938 · 2023 · External reference
Transcriptional Profiles of Mouse Oligodendrocyte Precursor Cells Across the Lifespan
10.1038/s43587-025-00840-2 · 2025 · External reference
Lifelong Cortical Myelin Plasticity and Age‐Related Degeneration in the Live Mammalian Brain
10.1038/s41593-018-0120-6 · 2018 · External reference
Oligodendrocyte Progenitors Balance Growth With Self‐Repulsion to Achieve Homeostasis in the Adult Brain
10.1038/nn.3390 · 2013 · External reference
Young CSF Restores Oligodendrogenesis and Memory in Aged Mice via Fgf17
10.1038/s41586-022-04722-0 · 2022 · External reference
Altered Human Oligodendrocyte Heterogeneity in Multiple Sclerosis
10.1038/s41586-019-0903-2 · 2019 · External reference
Single‐Nucleus Epigenomic Profiling of the Adult Human Central Nervous System Unveils Epigenetic Memory of Developmental Programs
10.1038/s41593-026-02208-0 · 2026 · External reference
Myelin Plasticity and Behaviour—Connecting the Dots
10.1016/j.conb.2017.09.014 · 2017 · External reference
Oligodendrocyte Precursor Cell AMPA Receptors Differ With Age and Brain Region While Kainate Receptors Remain Stable
10.1016/j.isci.2025.113560 · 2025 · External reference
NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and Following Neurodegeneration
10.1016/j.neuron.2010.09.009 · 2010 · External reference
NMDA Receptors Are Expressed in Oligodendrocytes and Activated in Ischaemia
10.1038/nature04302 · 2005 · External reference
Spiking and Nonspiking Classes of Oligodendrocyte Precursor Glia in CNS White Matter
10.1038/nn2060 · 2008 · External reference
CD8+ T Cells Induce Interferon‐Responsive Oligodendrocytes and Microglia in White Matter Aging
10.1038/s41593-022-01183-6 · 2022 · External reference
A Shared Disease‐Associated Oligodendrocyte Signature Among Multiple CNS Pathologies
10.1038/s41593-022-01104-7 · 2022 · External reference
Competing Waves of Oligodendrocytes in the Forebrain and Postnatal Elimination of an Embryonic Lineage
10.1038/nn1620 · 2005 · External reference
In Vivo Time‐Lapse Imaging Shows Dynamic Oligodendrocyte Progenitor Behavior During Zebrafish Development
10.1038/nn1803 · 2006 · External reference
Oligodendrocyte Precursor Cells Present Antigen and Are Cytotoxic Targets in Inflammatory Demyelination
10.1038/s41467-019-11638-3 · 2019 · External reference
Macrophage‐Depletion Induced Impairment of Experimental CNS Remyelination Is Associated With a Reduced Oligodendrocyte Progenitor Cell Response and Altered Growth Factor Expression
10.1016/j.nbd.2004.09.019 · 2005 · External reference
Signalling Through AMPA Receptors on Oligodendrocyte Precursors Promotes Myelination by Enhancing Oligodendrocyte Survival
10.7554/elife.28080 · 2017 · External reference
Cellular Architecture of Evolving Neuroinflammatory Lesions and Multiple Sclerosis Pathology
10.1016/j.cell.2024.02.030 · 2024 · External reference
Vesicular Glutamate Release From Axons in White Matter
10.1038/nn1850 · 2007 · External reference
Electrophysiological Properties of NG2+ Cells: Matching Physiological Studies With Gene Expression Profiles
10.1016/j.brainres.2015.09.010 · 2016 · External reference
Disease‐Associated Astrocyte Epigenetic Memory Promotes CNS Pathology
10.1038/s41586-024-07187-5 · 2024 · External reference
TREM2‐Independent Oligodendrocyte, Astrocyte, and T Cell Responses to Tau and Amyloid Pathology in Mouse Models of Alzheimer Disease
10.1016/j.celrep.2021.110158 · 2021 · External reference
Oligodendrocyte Precursors Guide Interneuron Migration by Unidirectional Contact Repulsion
10.1126/science.abn6204 · 2022 · External reference
Synaptic Signaling Between GABAergic Interneurons and Oligodendrocyte Precursor Cells in the Hippocampus
10.1038/nn1162 · 2004 · External reference
NG2 Glia Are Required for Maintaining Microglia Homeostatic State
10.1002/glia.23721 · 2020 · External reference
Functionally Distinct Subgroups of Oligodendrocyte Precursor Cells Integrate Neural Activity and Execute Myelin Formation
10.1038/s41593-019-0581-2 · 2020 · External reference
Transcriptional Convergence of Oligodendrocyte Lineage Progenitors During Development
10.1016/j.devcel.2018.07.005 · 2018 · External reference
Oligodendrocyte Heterogeneity in the Mouse Juvenile and Adult Central Nervous System
10.1126/science.aaf6463 · 2016 · External reference
Motor Skill Learning Requires Active Central Myelination
10.1126/science.1254960 · 2014 · External reference
Disease‐Specific Oligodendrocyte Lineage Cells Arise in Multiple Sclerosis
10.1038/s41591-018-0236-y · 2018 · External reference
Epigenomic Priming of Immune Genes Implicates Oligodendroglia in Multiple Sclerosis Susceptibility
10.1016/j.neuron.2021.12.034 · 2022 · External reference
M2 Microglia and Macrophages Drive Oligodendrocyte Differentiation During CNS Remyelination
10.1038/nn.3469 · 2013 · External reference
Myelin Is Repaired by Constitutive Differentiation of Oligodendrocyte Progenitors
10.1126/science.adu2896 · 2026 · External reference
Direct and Indirect Effects of Immune and Central Nervous System‐Resident Cells on Human Oligodendrocyte Progenitor Cell Differentiation
10.4049/jimmunol.1401156 · 2015 · External reference
Wrapped to Adapt: Experience‐Dependent Myelination
10.1016/j.neuron.2017.07.009 · 2017 · External reference
Demyelination Causes Adult CNS Progenitors to Revert to an Immature State and Express Immune Cues That Support Their Migration
10.1523/jneurosci.0849-14.2015 · 2015 · External reference
Inflammatory Memory and Tissue Adaptation in Sickness and in Health
10.1038/s41586-022-04919-3 · 2022 · External reference
NG2 Glial Cells Regulate Neuroimmunological Responses to Maintain Neuronal Function and Survival
10.1038/srep42041 · 2017 · External reference
Defining Trained Immunity and Its Role in Health and Disease
10.1038/s41577-020-0285-6 · 2020 · External reference
Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells
10.1016/j.stem.2019.08.015 · 2019 · External reference
Remyelination and Ageing: Reversing the Ravages of Time
2019 · External reference
Myc Determines the Functional Age State of Oligodendrocyte Progenitor Cells
10.1038/s43587-021-00109-4 · 2020 · External reference
Cellular Senescence in Progenitor Cells Contributes to Diminished Remyelination Potential in Progressive Multiple Sclerosis
2019 · External reference
Aberrant Oligodendroglial‐Vascular Interactions Disrupt the Blood–Brain Barrier, Triggering CNS Inflammation
2019 · External reference
Interneurons and Oligodendrocyte Progenitors Form a Structured Synaptic Network in the Developing Neocortex
10.7554/elife.06953 · 2015 · External reference
Dynamics of Mature Myelin
10.1038/s41593-024-01642-2 · 2024 · External reference
Disease‐Associated Oligodendrocyte Responses Across Neurodegenerative Diseases
10.1016/j.celrep.2022.111189 · 2022 · External reference
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
10.1126/science.1202529 · 2011 · External reference
Accelerated Cellular Senescence in Progressive Multiple Sclerosis: A Histopathological Study
10.1002/ana.27195 · 2025 · External reference
Cell Cycle Dynamics of NG2 Cells in the Postnatal and Ageing Brain
10.1017/s1740925x09990354 · 2009 · External reference
Myelin Plasticity in the Central Nervous System
10.1016/j.neuropharm.2015.08.001 · 2016 · External reference
Nonlinear Associations of Neurite Density and Myelin Content With Age Revealed Using Multicomponent Diffusion and Relaxometry Magnetic Resonance Imaging
2020 · External reference
A Glial Progenitor Cell That Develops In Vitro Into an Astrocyte or an Oligodendrocyte Depending on Culture Medium
10.1038/303390a0 · 1983 · External reference
The Injury Response of Oligodendrocyte Precursor Cells Is Induced by Platelets, Macrophages and Inflammation‐Associated Cytokines
10.1016/j.neuroscience.2006.01.055 · 2006 · External reference
Oligodendrocyte Wars
2006 · External reference
PDGFRA/NG2 Glia Generate Myelinating Oligodendrocytes and Piriform Projection Neurons in Adult Mice
10.1038/nn.2220 · 2008 · External reference
Rejuvenation of Regeneration in the Aging Central Nervous System
10.1016/j.stem.2011.11.019 · 2012 · External reference
Brain Borders at the Central Stage of Neuroimmunology
10.1038/s41586-022-05474-7 · 2022 · External reference
White Matter Aging Drives Microglial Diversity
10.1016/j.neuron.2021.01.027 · 2021 · External reference
Age‐Related Myelin Degradation Burdens the Clearance Function of Microglia During Aging
10.1038/nn.4325 · 2016 · External reference
Oligodendrocyte Precursor Cells Modulate the Neuronal Network by Activity‐Dependent Ectodomain Cleavage of Glial NG2
10.1371/journal.pbio.1001993 · 2014 · External reference
Glia: Victims or Villains of the Aging Brain?
10.1016/j.nbd.2020.105008 · 2020 · External reference
Motor Skill Learning Induces Changes in White Matter Microstructure and Myelination
10.1523/jneurosci.3048-13.2013 · 2013 · External reference
Training Induces Changes in White Matter Architecture
10.1038/nn.2412 · 2009 · External reference
Niche Stiffness Underlies the Ageing of Central Nervous System Progenitor Cells
10.1038/s41586-019-1484-9 · 2019 · External reference
Oligodendrocyte Precursor Cells Support Blood‐Brain Barrier Integrity via TGF‐β Signaling
10.1371/journal.pone.0103174 · 2014 · External reference
Oligodendrocyte Precursors Induce Early Blood–Brain Barrier Opening After White Matter Injury
2013 · External reference
Remyelination Occurs as Extensively but More Slowly in Old Rats Compared to Young Rats Following Fliotoxin‐Induced CNS Demyelination
10.1002/(sici)1098-1136(20000101)29:1<102::aid-glia12>3.0.co;2-1 · 2000 · External reference
The Age‐Related Decrease in CNS Remyelination Efficiency Is Attributable to an Impairment of Both Oligodendrocyte Progenitor Recruitment and Differentiation
10.1523/jneurosci.22-07-02451.2002 · 2002 · External reference
Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous With Age
10.1016/j.neuron.2018.12.020 · 2019 · External reference
Disruption of Oligodendrogenesis Impairs Memory Consolidation in Adult Mice
10.1016/j.neuron.2019.10.013 · 2020 · External reference
The Classical Complement Cascade Mediates CNS Synapse Elimination
10.1016/j.cell.2007.10.036 · 2007 · External reference
Lack of Replicative Senescence in Cultured Rat Oligodendrocyte Precursor Cells
10.1126/science.1056780 · 2001 · External reference
Long‐Term In Vivo Three‐Photon Imaging Reveals Region‐Specific Differences in Healthy and Regenerative Oligodendrogenesis
10.1038/s41593-024-01613-7 · 2024 · External reference
Neuron‐Oligodendroglia Interactions: Activity‐Dependent Regulation of Cellular Signalling
10.1016/j.neulet.2020.134916 · 2020 · External reference
Innate Immune Training Restores Pro‐Reparative Myeloid Functions to Promote Remyelination in the Aged Central Nervous System
10.1016/j.immuni.2024.07.001 · 2024 · External reference
Dorsally and Ventrally Derived Oligodendrocytes Have Similar Electrical Properties but Myelinate Preferred Tracts
10.1523/jneurosci.6474-10.2011 · 2011 · External reference
NG2 Glia Generate New Oligodendrocytes but Few Astrocytes in a Murine Experimental Autoimmune Encephalomyelitis Model of Demyelinating Disease
10.1523/jneurosci.3411-10.2010 · 2010 · External reference
Oligodendrocyte Precursors Migrate Along Vasculature in the Developing Nervous System
10.1126/science.aad3839 · 2016 · External reference
Transplantation Reveals Regional Differences in Oligodendrocyte Differentiation in the Adult Brain
2013 · External reference
Myelin Degeneration and Diminished Myelin Renewal Contribute to Age‐Related Deficits in Memory
2020 · External reference
Oligodendroglial Precursor Cells Modulate Immune Response and Early Demyelination in a Murine Model of Multiple Sclerosis
10.1126/scitranslmed.adn9980 · 2025 · External reference
Innate Immune Memory in the Brain Shapes Neurological Disease Hallmarks
10.1038/s41586-018-0023-4 · 2018 · External reference
Myelin Dynamics Throughout Life: An Ever‐Changing Landscape?
10.3389/fncel.2018.00424 · 2018 · External reference
Physiological Aging and Inflammation‐Induced Cellular Senescence May Contribute to Oligodendroglial Dysfunction in MS
10.1007/s00401-024-02733-x · 2024 · External reference
Alterations of Myelin Morphology and Oligodendrocyte Development in Early Stage of Alzheimer's Disease Mouse Model
10.1016/j.neulet.2017.02.007 · 2017 · External reference
Myelination‐Independent Functions of Oligodendrocyte Precursor Cells in Health and Disease
10.1038/s41593-023-01423-3 · 2023 · External reference
Oligodendrocyte Precursor Cells Sculpt the Visual System by Regulating Axonal Remodeling
10.1038/s41593-022-01023-7 · 2022 · External reference
Single‐Cell Transcriptomic Profiling of the Aging Mouse Brain
10.1038/s41593-019-0491-3 · 2019 · External reference
Myelin Plasticity: Sculpting Circuits in Learning and Memory
10.1038/s41583-020-00379-8 · 2020 · External reference
Myelin Plasticity in the Ventral Tegmental Area Is Required for Opioid Reward
10.1038/s41586-024-07525-7 · 2024 · External reference
Oligodendrocyte‐Encoded HIF Function Couples Postnatal Myelination and White Matter Angiogenesis
10.1016/j.cell.2014.04.052 · 2014 · External reference
CNS‐Resident Glial Progenitor/Stem Cells Produce Schwann Cells as Well as Oligodendrocytes During Repair of CNS Demyelination
10.1016/j.stem.2010.04.002 · 2010 · External reference
Senolytic Therapy Alleviates Aβ‐Associated Oligodendrocyte Progenitor Cell Senescence and Cognitive Deficits in an Alzheimer's Disease Model
10.1038/s41593-019-0372-9 · 2019 · External reference
NG2 Glia Regulate Brain Innate Immunity via TGF‐β2/TGFBR2 Axis
10.1186/s12916-019-1439-x · 2019 · External reference
Astrocytes and Oligodendrocytes Can Be Generated From NG2+ Progenitors After Acute Brain Injury: Intracellular Localization of Oligodendrocyte Transcription Factor 2 Is Associated With Their Fate Choice
10.1111/j.1460-9568.2009.06736.x · 2009 · External reference
Distinct Transcriptomic and Epigenomic Responses of Mature Oligodendrocytes During Disease Progression in a Mouse Model of Multiple Sclerosis
10.1038/s41593-025-02100-3 · 2025 · External reference
NG2 Cells Generate Both Oligodendrocytes and Gray Matter Astrocytes
10.1242/dev.004895 · 2008 · External reference
Cerebrospinal Fluid of Progressive Multiple Sclerosis Patients Reduces Differentiation and Immune Functions of Oligodendrocyte Progenitor Cells
10.1002/glia.24165 · 2022 · External reference
The Interplay of Inflammation and Remyelination: Rethinking MS Treatment With a Focus on Oligodendrocyte Progenitor Cells
10.1186/s13024-024-00742-8 · 2024 · External reference