Research graph
References from Neural Cell Models of Specific Reading Disabilities: Identification of Cellular and Transcriptome Alterations. Local targets link to admitted publications; unresolved targets remain external evidence.
Incidence of Reading Disability in a Population‐Based Birth Cohort, 1976‐1982, Rochester, Minn
10.4065/76.11.1081 · 2001 · External reference
Developmental Dyslexia
10.1016/s0140-6736(12)60198-6 · 2012 · External reference
10.1037/10131-006
10.1037/10131-006 · 1993 · External reference
The Genetics of Dyslexia
10.1111/j.1469-7610.1990.tb01561.x · 1990 · External reference
Developmental Dyslexia: An Update on Genes, Brains, and Environments
10.1111/1469-7610.00704 · 2001 · External reference
Unresolved reference
2008 · External reference
The Heritability of Reading and Reading‐Related Neurocognitive Components: A Multi‐Level Meta‐Analysis
10.1016/j.neubiorev.2020.11.016 · 2021 · External reference
Unresolved reference
External reference
Remediating the Core Deficits of Developmental Reading Disability: A Double Deficit Perspective
10.1177/002221940003300406 · 2000 · External reference
Multiple‐Component Remediation for Developmental Reading Disabilities: IQ, Socioeconomic Status, and Race as Factors in Remedial Outcome
10.1177/0022219409355472 · 2012 · External reference
Recognizing Psychiatric Comorbidity With Reading Disorders
10.3389/fpsyt.2018.00101 · 2018 · External reference
Developmental Dyslexia: Four Consecutive Patients With Cortical Anomalies
10.1002/ana.410180210 · 1985 · External reference
Developmental Dyslexia in Women: Neuropathological Findings in Three Patients
10.1002/ana.410280602 · 1990 · External reference
The Neuronal Migration Hypothesis of Dyslexia: A Critical Evaluation 30 Years on
10.1111/ejn.14149 · 2018 · External reference
Hypothesis‐Driven Genome‐Wide Association Studies Provide Novel Insights Into Genetics of Reading Disabilities
10.1038/s41398-022-02250-z · 2022 · External reference
Genome‐Wide Association Study of Word Reading: Overlap With Risk Genes for Neurodevelopmental Disorders
10.1111/gbb.12648 · 2020 · External reference
Genome‐Wide Analyses of Individual Differences in Quantitatively Assessed Reading‐ and Language‐Related Skills in up to 34,000 People
10.1073/pnas.2202764119 · 2022 · External reference
Discovery of 42 Genome‐Wide Significant Loci Associated With Dyslexia
10.1038/s41588-022-01192-y · 2022 · External reference
Unresolved reference
2011 · External reference
Unresolved reference
1993 · External reference
Association of the ROBO1 Gene With Reading Disabilities in a Family‐Based Analysis
10.1111/gbb.12126 · 2014 · External reference
Association of Reading Disabilities With Regions Marked by Acetylated H3 Histones in KIAA0319
2010 · External reference
Genetic Variation in the KIAA0319 5' Region as a Possible Contributor to Dyslexia
10.1007/s10519-010-9434-1 · 2011 · External reference
Unresolved reference
1997 · External reference
Evaluation of the Revised Ontario Child Health Study Scales
10.1111/j.1469-7610.1993.tb00979.x · 1993 · External reference
Children's Interview for Psychiatric Syndromes (ChIPS)
2000 · External reference
Unresolved reference
2002 · External reference
PennCNV: An Integrated Hidden Markov Model Designed for High‐Resolution Copy Number Variation Detection in Whole‐Genome SNP Genotyping Data
10.1101/gr.6861907 · 2007 · External reference
Integrated Study of Copy Number States and Genotype Calls Using High‐Density SNP Arrays
10.1093/nar/gkp493 · 2009 · External reference
Altered Proliferation and Networks in Neural Cells Derived From Idiopathic Autistic Individuals
10.1038/mp.2016.95 · 2017 · External reference
A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells
10.1016/j.cell.2010.10.016 · 2010 · External reference
Phenotypic Differences in hiPSC NPCs Derived From Patients With Schizophrenia
10.1038/mp.2014.22 · 2015 · External reference
NIH Image to ImageJ: 25 Years of Image Analysis
10.1038/nmeth.2089 · 2012 · External reference
FASTP: An Ultra‐Fast All‐in‐One FASTQ Preprocessor
10.1093/bioinformatics/bty560 · 2018 · External reference
STAR: Ultrafast Universal RNA‐seq Aligner
10.1093/bioinformatics/bts635 · 2013 · External reference
HTSeq – A Python Framework to Work With High‐Throughput Sequencing Data
10.1093/bioinformatics/btu638 · 2015 · External reference
Moderated Estimation of Fold Change and Dispersion for RNA‐Seq Data With DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
Unresolved reference
2024 · External reference
10.1007/978-3-319-24277-4
10.1007/978-3-319-24277-4 · 2016 · External reference
Gene Set Enrichment Analysis: A Knowledge‐Based Approach for Interpreting Genome‐Wide Expression Profiles
10.1073/pnas.0506580102 · 2005 · External reference
Genome‐Wide Copy Number Scan Identifies Disruption of PCDH11X in Developmental Dyslexia
10.1002/ajmg.b.32199 · 2013 · External reference
Critical Periods in Speech Perception: New Directions
10.1146/annurev-psych-010814-015104 · 2015 · External reference
Re‐Opening Windows: Manipulating Critical Periods for Brain Development
2012 · External reference
Insulin‐Like Growth Factor 1 (IGF‐1) Mediates the Effects of Enriched Environment (EE) on Visual Cortical Development
10.1371/journal.pone.0000475 · 2007 · External reference
Characterization of a Novel OTX2‐Driven Stem Cell Program in Group 3 and Group 4 Medulloblastoma
10.1002/1878-0261.12177 · 2018 · External reference
Genome‐Wide Target Analyses of Otx2 Homeoprotein in Postnatal Cortex
10.3389/fnins.2017.00307 · 2017 · External reference
OTX2 Regulates CFTR Expression During Endoderm Differentiation and Occupies 3′ Cis‐Regulatory Elements
10.1002/dvdy.293 · 2021 · External reference
OTX2 Homeoprotein Functions in Adult Choroid Plexus
10.3390/ijms22168951 · 2021 · External reference
Dysregulation of miRNA‐9 in a Subset of Schizophrenia Patient‐Derived Neural Progenitor Cells
10.1016/j.celrep.2016.03.090 · 2016 · External reference
Stem‐Cell Derived Neurosphere Assay Highlights the Effects of Viral Infection on Human Cortical Development
10.1016/j.bbi.2023.11.017 · 2024 · External reference
Dysregulation of mTOR Signaling Mediates Common Neurite and Migration Defects in Both Idiopathic and 16p11.2 Deletion Autism Neural Precursor Cells
10.7554/elife.82809 · 2024 · External reference
Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation
10.3389/ftox.2022.816370 · 2022 · External reference
Species‐Specific Maturation Profiles of Human, Chimpanzee and Bonobo Neural Cells
10.7554/elife.37527 · 2019 · External reference
Mechanisms and Disturbances of Neuronal Migration
10.1203/00006450-200012000-00004 · 2000 · External reference
Divergence and Inheritance of Neocortical Heterotopia in Inbred and Genetically‐Engineered Mice
10.1016/j.neulet.2016.12.038 · 2017 · External reference
Position of Neocortical Neurons Transfected at Different Gestational Ages With shRNA Targeted Against Candidate Dyslexia Susceptibility Genes
10.1371/journal.pone.0065179 · 2013 · External reference
Essential Role of the Nuclear Isoform of RBFOX1, a Candidate Gene for Autism Spectrum Disorders, in the Brain Development
10.1038/srep30805 · 2016 · External reference
Genetic Compensation Induced by Deleterious Mutations but Not Gene Knockdowns
10.1038/nature14580 · 2015 · External reference
Genes, Brain, and Cognition: A Roadmap for the Cognitive Scientist
10.1016/j.cognition.2006.04.003 · 2006 · External reference
Language Comprehension in Language‐Learning Impaired Children Improved With Acoustically Modified Speech
10.1126/science.271.5245.81 · 1996 · External reference
Does Successful Training of Temporal Processing of Sound and Phoneme Stimuli Improve Reading and Spelling?
10.1007/s00787-006-0500-4 · 2006 · External reference
Plastic Neural Changes and Reading Improvement Caused by Audiovisual Training in Reading‐Impaired Children
10.1073/pnas.181589198 · 2001 · External reference
Working Memory, Short‐Term Memory, and Reading Disabilities: A Selective Meta‐Analysis of the Literature
10.1177/0022219409331958 · 2009 · External reference
Executive Working Memory Processes in Dyslexia: Behavioral and fMRI Evidence
10.1111/j.1467-9450.2010.00808.x · 2010 · External reference
Mutation of Dcdc2 in Mice Leads to Impairments in Auditory Processing and Memory Ability
10.1111/gbb.12170 · 2014 · External reference
Gene Discovery and Polygenic Prediction From a Genome‐Wide Association Study of Educational Attainment in 1.1 Million Individuals
10.1038/s41588-018-0147-3 · 2018 · External reference
The Genetic Architecture of Human Cortical Folding
10.1126/sciadv.abj9446 · 2021 · External reference
Vertex‐Wise Multivariate Genome‐Wide Association Study Identifies 780 Unique Genetic Loci Associated With Cortical Morphology
10.1016/j.neuroimage.2021.118603 · 2021 · External reference
10.1126/sciadv.abj9446
10.1126/sciadv.abj9446 · External reference
Brain Structure, Phenotypic and Genetic Correlates of Reading Performance
10.1038/s41562-023-01583-z · 2023 · External reference
Aberrant Otx2 Expression Enhances Migration and Induces Ectopic Proliferation of Hindbrain Neuronal Progenitor Cells
10.1371/journal.pone.0036211 · 2012 · External reference
Layer I Ectopias and Increased Excitability in Murine Neocortex
10.1152/jn.2002.87.5.2471 · 2002 · External reference
Neuronal Migration Disorders: Focus on the Cytoskeleton and Epilepsy
10.1016/j.nbd.2015.08.003 · 2016 · External reference
Neural Noise Hypothesis of Developmental Dyslexia
10.1016/j.tics.2017.03.008 · 2017 · External reference
Excitatory Projection Neuron Subtypes Control the Distribution of Local Inhibitory Interneurons in the Cerebral Cortex
10.1016/j.neuron.2011.01.015 · 2011 · External reference
Cell Migration Promotes Dynamic Cellular Interactions to Control Cerebral Cortex Morphogenesis
10.1038/s41583-019-0148-y · 2019 · External reference
Glutamate and Choline Levels Predict Individual Differences in Reading Ability in Emergent Readers
10.1523/jneurosci.3907-13.2014 · 2014 · External reference
Greater Reading Gain Following Intervention Is Associated With Low Magnetic Resonance Spectroscopy Derived Concentrations in the Anterior Cingulate Cortex in Children With Dyslexia
10.1016/j.brainres.2021.147386 · 2021 · External reference
Unstable Representation of Sound: A Biological Marker of Dyslexia
10.1523/jneurosci.4205-12.2013 · 2013 · External reference
Reevaluating the Neural Noise in Dyslexia Using Biomarkers From Electroencephalography and High‐Resolution Magnetic Resonance Spectroscopy
10.7554/elife.99920.4 · 2025 · External reference
Neural Excitation/Inhibition Imbalance and Neurodevelopmental Pathology in Human Copy Number Variant Syndromes: A Systematic Review
10.1186/s11689-025-09614-8 · 2025 · External reference
Increased Glutamate Concentration in the Auditory Cortex of Persons With Autism and First‐Degree Relatives: A (1)H‐MRS Study
10.1002/aur.1260 · 2013 · External reference
Model of Autism: Increased Ratio of Excitation/Inhibition in Key Neural Systems
10.1034/j.1601-183x.2003.00037.x · 2003 · External reference
Excitation/Inhibition Imbalance in Animal Models of Autism Spectrum Disorders
10.1016/j.biopsych.2016.05.011 · 2017 · External reference
Neural Hyperexcitability in Autism Spectrum Disorders
10.3390/brainsci7100129 · 2017 · External reference
Striatal Creatine and Glutamate/Glutamine in Attention‐Deficit/Hyperactivity Disorder
10.1089/cap.2006.0008 · 2007 · External reference
Brain Biochemical Effects of Methylphenidate Treatment Using Proton Magnetic Spectroscopy in Youth With Attention‐Deficit Hyperactivity Disorder: A Controlled Pilot Study
10.1111/j.1755-5949.2010.00226.x · 2012 · External reference
Genetics of Attention Deficit Hyperactivity Disorder
10.1038/s41380-018-0070-0 · 2019 · External reference
Sensitive and Critical Periods During Neurotypical and Aberrant Neurodevelopment: A Framework for Neurodevelopmental Disorders
10.1016/j.neubiorev.2014.12.001 · 2015 · External reference
Critical Aspects of Neurodevelopment
10.1016/j.nlm.2021.107415 · 2021 · External reference
The Shape of the Human Language‐Ready Brain
10.3389/fpsyg.2014.00282 · 2014 · External reference
The Role of GABAergic Inhibition in Ocular Dominance Plasticity
10.1155/2011/391763 · 2011 · External reference
Experience‐Dependent Transfer of Otx2 Homeoprotein Into the Visual Cortex Activates Postnatal Plasticity
10.1016/j.cell.2008.05.054 · 2008 · External reference
Developmental Pathway Genes and Neural Plasticity Underlying Emotional Learning and Stress‐Related Disorders
10.1101/lm.044271.116 · 2017 · External reference
Choroid‐Plexus‐Derived Otx2 Homeoprotein Constrains Adult Cortical Plasticity
10.1016/j.celrep.2013.05.014 · 2013 · External reference
Otx2 Binding to Perineuronal Nets Persistently Regulates Plasticity in the Mature Visual Cortex
10.1523/jneurosci.0394-12.2012 · 2012 · External reference
OTX2 Signaling in Retinal Dysfunction, Degeneration and Regeneration
10.4103/1673-5374.308094 · 2021 · External reference
Exogenous Otx2 Protects Midbrain Dopaminergic Neurons From MPP
10.1016/j.neuro.2022.05.013 · 2022 · External reference
The Role of Insulin/IGF1 Signalling in Neurodevelopmental and Neuropsychiatric Disorders ‐ Evidence From Human Neuronal Cell Models
10.1016/j.neubiorev.2023.105330 · 2023 · External reference
Insulin‐Like Growth Factor 1 and Related Compounds in the Treatment of Childhood‐Onset Neurodevelopmental Disorders
10.3389/fnins.2016.00450 · 2016 · External reference
Clinical Trial of Insulin‐Like Growth Factor‐1 in Phelan‐McDermid Syndrome
10.1186/s13229-022-00493-7 · 2022 · External reference
Identification of Brain Cell Types Underlying Genetic Association With Word Reading and Correlated Traits
10.1038/s41380-023-01970-y · 2023 · External reference
