Research graph
References from Topical and systemic antibiotics in the management of periodontal diseases. Local targets link to admitted publications; unresolved targets remain external evidence.
Suppression of the periodontopathic microflora in localized juvenile periodontitis by systemic tetracycline
10.1111/j.1600-051x.1983.tb02179.x · 1983 · External reference
Microbiological and clinical effects of surgical treatment of localized juvenile periodontitis
10.1111/j.1600-051x.1985.tb01382.x · 1985 · External reference
Clinical and microbiological evaluation of therapy for juvenile periodontitis
10.1902/jop.1985.56.8.443 · 1985 · External reference
Effect of modified Widman flap surgery and systemic tetracycline on the subgingival microbiota of periodontal lesions
10.1111/j.1600-051x.1988.tb01579.x · 1988 · External reference
Occurrence of Bacteroides gingivalis Bacteroides intermedius and Actinobacillus actinomy-cetemcomitans in severe periodontitis in relation to age and treatment hisory
10.1111/j.1600-051x.1990.tb00036.x · 1990 · External reference
The occurrence of Actinobacillus actinomycetemcomitans Bacteroides gingivalis and Bacteroides intermedius in destructive periodontal disease in adults
10.1111/j.1600-051x.1986.tb00849.x · 1986 · External reference
The capability of Actinobacillus actinomycetemcomitans Bacteroides gingivalis and Bacteroides intermedius to indicate progressive periodontitis; a retrospective study
10.1111/j.1600-051x.1987.tb00949.x · 1995 · External reference
Bacteroides gingivalis Bacteroides intermedius and Actinobacillus actinomycetemcomitans in human periodontal diseases
10.1111/j.1600-051x.1988.tb00999.x · 1988 · External reference
Microbial identification and antibiotic sensitivity testing an aid for patients refractory to periodontal therapy
10.1111/j.1600-051x.1994.tb00286.x · 1994 · External reference
The utility of 5 major putative periodontal pathogens and selected clinical parameters to predict periodontal breakdown in adults on maintenance care
10.1111/j.1600-051x.1996.tb00556.x · 1996 · External reference
Actinobacillus actinomycetemcomitans Bacteroides gingivalis and Bacteroides intermedius: Predictors of attachment loss
10.1111/j.1399-302x.1987.tb00300.x · 1987 · External reference
Treatment of periodontal disease based on microbiological diagnosis. A 5-year follow-up on individual patterns
10.1902/jop.1996.67.9.879 · 1996 · External reference
Actinobacillus actinomycetemcomitans in adult periodontitis. I. Topographic distribution before and after treatment
10.1902/jop.1994.65.9.820 · 1994 · External reference
Persistence patterns of Porphyromonas gingivalis Prevotella intermedia/nigrescens and Actinobacillus actino-mycetem-comitans after mechanical therapy of periodontal disease
10.1902/jop.2000.71.1.14 · 2000 · External reference
Testing the susceptibility of bacteria in biofilms to antibacterial agents
10.1128/aac.34.11.2043 · 1990 · External reference
Establishment of aging biofilms: possible mechanism of bacterial resistance to antibiotic therapy
10.1128/aac.36.7.1347 · 1992 · External reference
Bacterial biofilms: a common cause of persistent infections
10.1126/science.284.5418.1318 · 1990 · External reference
Unresolved reference
2002 · External reference
Systemic antibiotic therapy in periodontics
10.1111/j.1600-0757.1996.tb00068.x · 1996 · External reference
Bacterial diversity within the human subgingival crevice
10.1073/pnas.96.25.14547 · 2001 · External reference
Black-pigmenting Gram-negative bacteria in periodontal disease. I. Topographic distribution in the human dentition
10.1111/j.1600-0765.1991.tb02067.x · 1991 · External reference
Black-pigmented Bacteroides spp. in the human oral cavity
10.1128/iai.32.1.198-203.1981 · 1981 · External reference
Intra-oral distribution of black-pigmented Bacteroides species in periodontitis patients
10.1111/j.1399-302x.1988.tb00087.x · 1988 · External reference
Failure of adjunctive minocycline-HC1 to eliminate oral Actinobacillus actinomycetemcomitans
10.1111/j.1600-051x.1993.tb00397.x · 1993 · External reference
Microbiological and clinical effects of metronidazole and amoxicillin in Actinobacillus actinomycetemcomitans-associated periodontitis
10.1111/j.1600-051x.1994.tb00287.x · 1994 · External reference
Simultaneous isolation of Actinobacillus actinomycetemcomitans from subgingival and extra-crevicular locations of the mouth
10.1111/j.1600-051x.1995.tb00169.x · 1995 · External reference
Access to subgingival plaque by disclosing agents using mouthrinsing and direct irrigation
10.1111/j.1600-051x.1980.tb01972.x · 1980 · External reference
Depth of penetration in periodontal pockets with oral irrigation
10.1111/j.1600-051x.1986.tb01412.x · 1986 · External reference
Pharmacokinetic principles controlling efficacy of oral therapy
1989 · External reference
Clearance of a topically applied fluorescein gel from periodontal pockets
10.1111/j.1600-051x.1990.tb01681.x · 1990 · External reference
Elimination of Elyzol® 25% Dentalgel matrix from periodontal pockets
10.1111/j.1600-051x.1995.tb00133.x · 1995 · External reference
Further evidence that tetracyclines inhibit collagenase activity in human crevicular fluid and other mammalian sources
10.1111/j.1600-0765.1985.tb00405.x · 1985 · External reference
Antimicrobial properties of human dentin impregnated with tetracycline HC1 or chlorhexidine. An in vitro study
10.1111/j.1600-051x.1993.tb00771.x · 1993 · External reference
Metronidazole plus amoxicillin in the treatment of Actinobacillus actinomycetemcomitans associated periodontitis
10.1111/j.1600-051x.1989.tb01626.x · 1989 · External reference
Activity of metronidazole and its hydroxy-metabolite
10.1111/j.1399-302x.1988.tb00602.x · 1988 · External reference
Synergistic effects between amoxicillin metronidazole and the hydroxymetabolite of metronidazole against Actinobacillus actinomycetemcomitans
10.1128/aac.35.5.961 · 1991 · External reference
In vitro susceptibilities of Actinobacillus actinomycetemcomitans to a number of antimicrobial combinations
10.1128/aac.36.12.2634 · 1992 · External reference
A systematic review on the effect of systemic antimicrobials as an adjunct to scaling and root planing in periodontitis patients
10.1034/j.1600-051x.29.s3.8.x · 2002 · External reference
Chemotherapy of periodontal diseases
2002 · External reference
Effect of tetracycline and/or scaling on human periodontal disease
10.1111/j.1600-051x.1978.tb01918.x · 1978 · External reference
The effect of tetracycline and/or scaling on human periodontal disease
10.1111/j.1600-051x.1979.tb01924.x · 1979 · External reference
Periodontal therapy in humans. I. Microbiological and clinical effects of a single course of periodontal scaling and root and of adjunctive tetracycline therapy
10.1902/jop.1979.50.10.495 · 1979 · External reference
Tetracycline: a clinical study to determine its effectiveness as long-term adjuvant
10.1902/jop.1980.51.6.328 · 1980 · External reference
Effect of long-term tetracycline therapy on human periodontal disease
10.1111/j.1600-051x.1983.tb01297.x · 1983 · External reference
Effectiveness of routine periodontal treatment with and without adjunctive metronidazole therapy in mentally retarded adolescents
10.1902/jop.1983.54.11.658 · 1983 · External reference
The effect of metronidazole on human periodontal disease. A clinical and bacteriological study
10.1902/jop.1983.54.8.476 · 1983 · External reference
Effect of metronidazole on chronic periodontal disease in subjects using topically applied chlorhexidine gel
10.1111/j.1600-051x.1984.tb01308.x · 1984 · External reference
Metronidazole in periodontitis. I. Clinical and bacteriological results after 15 to 30 weeks
10.1902/jop.1984.55.6.325 · 1984 · External reference
A follow-up study 3 years after metronidazole therapy for chronic periodontal disease
10.1111/j.1600-051x.1986.tb01432.x · 1986 · External reference
The effect of systemic metronidazole after non-surgical treatment in moderate and advanced periodontitis
10.1902/jop.1990.61.5.281 · 1990 · External reference
Metronidazole as an adjunct to periodontal therapy with subgingival curettage
10.1038/sj.bdj.4805568 · 1985 · External reference
The value of systemically administered metronidazole in the modified Widman flap procedure
10.1902/jop.1987.58.3.147 · 1987 · External reference
The effects of metronidazole in treatment of young adults with severe periodontitis
1989 · External reference
Microbiological and clinical effects of systemic antibiotic administration in advanced periodontitis
1986 · External reference
Clinical and microbiological changes associated with the use of 4 adjunctive systemically administered agents in the treatment of periodontal infections
10.1111/j.1600-051x.1995.tb00815.x · 1995 · External reference
Systemic antibiotic combination therapy in recalcitrant and recurrent localized juvenile periodontitis
1989 · External reference
Treatment of refractory periodontitis with metronidazole plus amoxicillin or Augmentin
1989 · External reference
Microbiology in diagnosis and treatment of severe periodontitis. A report of four cases
10.1902/jop.1990.61.1.61 · 1990 · External reference
Ciprofloxacin/metronidazole treatment of recurrent adult periodontitis
1992 · External reference
Microbiological and clinical results of metronidazole plus amoxicillin therapy in Actinobacillus actinomycetemcomitans-associated periodontitis
10.1902/jop.1992.63.1.52 · 1992 · External reference
Adjunctive effects to non-surgical therapy of systemic metronidazole and amoxycillin alone alone and combined. A placebo controlled study
10.1034/j.1600-051x.2002.290410.x · 2002 · External reference
Differential clinical treatment outcome after systemic metronidazole and amoxicillin in patients harboring Actinobacillus actinomycetemcomitans and/or Porphyromonas gingivalis
10.1111/j.1600-051x.1998.tb02459.x · 1998 · External reference
Guidelines for the use of antimicrobial agents to minimise the development of resistance
10.1111/j.1875-595x.1999.tb00521.x · 1999 · External reference
A rationale for the management of periodontal diseases: effects of tetracycline on subgingival bacteria
10.14219/jada.archive.1983.0177 · 1983 · External reference
Efficacy of doxycycline in prevention of recurrent periodontitis
1989 · External reference
Randomised controlled trial of doxycycline in prevention of recurent periodontitis in high risk patients: antimicrobial activity and collagenase inhibition
10.1111/j.1600-051x.1990.tb01682.x · 1990 · External reference
Serial doxycycline and metronidazole in prevention of recurrent periodontitis in high risk patients
10.1902/jop.1992.63.2.87 · 1992 · External reference
A role for antibiotics in the treatment of refractory periodontitis
10.1902/jop.1993.64.8s.772 · 1993 · External reference
Die Reduktion von A. actinomycetemcomitans bei der profunden Parodontitis
1989 · External reference
Clinical and microbiological study of ‘refractory’ adult periodontitis
1985 · External reference
Evaluation of two antibacterial agents in the management of rapidly progressive periodontitis
1989 · External reference
Unresolved reference
1989 · External reference
Efficacy of clindamycin hydrochloride in refractory periodontitis. 12 month results
10.1902/jop.1985.56.11s.75 · 1985 · External reference
The effect of clindamycin on the microbiota associated with refractory periodontitis
10.1902/jop.1990.61.11.692 · 1990 · External reference
Treatment of subjects with refractory periodontal disease
10.1111/j.1600-051x.1994.tb00755.x · 1994 · External reference
Combined antibiotic (metronidazole) and mechanical treatment effects on the subgingival bacterial flora of sites with recurrent periodontal disease
10.1111/j.1600-051x.1988.tb01011.x · 1988 · External reference
Treatment of recurrent periodontal disease by root planing and Ornidazole (Tiberal®). Clinical and microbiological findings
10.1111/j.1600-051x.1989.tb01610.x · 1989 · External reference
Treatment of localized juvenile periodontitis
1981 · External reference
Treatment of localized juvenile periodontitis
1983 · External reference
Metronidazole in the treatment of localized juvenile periodontitis
10.1111/j.1600-051x.1993.tb00339.x · 1993 · External reference
Black-pigmenting Gram-negative bacteria in periodontal disease. II. Screening strategies for P. gingivalis
10.1111/j.1600-0765.1991.tb02068.x · 1991 · External reference
The influence of supragingival plaque control on clinical and microbial outcomes following the use of antibiotics for the treatment of periodontitis
10.1902/jop.1994.65.9.848 · 1994 · External reference
Monolithic tetracycline containing fibers for controlled delivery to periodontal pockets
10.1902/jop.1983.54.10.575 · 1983 · External reference
Multicenter evaluation of tetracycline fiber therapy: I. Experimental design methods and baseline data
10.1111/j.1600-0765.1991.tb02075.x · 1991 · External reference
Periodontal disease treatment by local drug delivery
10.1902/jop.1985.56.5.265 · 1985 · External reference
Serum levels of tetracycline during treatment with tetracycline-containing fibers
10.1902/jop.1992.63.10.817 · 1992 · External reference
Multicenter evaluation of tetracycline fiber therapy: II. Clinical response
10.1111/j.1600-0765.1991.tb02076.x · 1991 · External reference
A 6-month multi-center evaluation of adjunctive tetracycline fiber therapy used in conjunction with scaling and root in maintenance patients: Clinical results
10.1902/jop.1994.65.7.685 · 1994 · External reference
Evaluation of periodontal treatments using controlled release tetracycline fibers: Maintenance response
10.1902/jop.1995.66.8.708 · 1995 · External reference
Subgingival minocycline hydrochloride ointment in moderate to severe chronic adult periodontitis: A randomized doubleblind vehicle-controlled multicenter study
10.1902/jop.1993.64.7.637 · 1993 · External reference
Effect of repeated local minocycline administration on periodontal healing following guided tissue regeneration
10.1902/jop.2001.72.3.284 · 2001 · External reference
Treatment of periodontitis by local administration of minocycline microspheres: a controlled trial
10.1902/jop.2001.72.11.1535 · 2001 · External reference
Two multi-center studies evaluating locally delivered doxycycline hyclate placebo control oral hygiene and scaling and root planing in the treatment of periodontitis
10.1902/jop.1999.70.5.490 · 1999 · External reference
The effect of locally delivered controlled-release doxycycline or scaling and root planing on periodontal maintenance patients over 9 months
10.1902/jop.2000.71.1.22 · 2000 · External reference
Utilization of locally delivered doxycycline in non-surgical treatment of chronic periodontitis. A comparative multi-center trial of 2 treatment approaches
10.1034/j.1600-051x.2001.280806.x · 2001 · External reference
Systemic absorbtion of metronidazole after application of a metronidazole 25% dental gel
10.1111/j.1600-051x.1992.tb02530.x · 1992 · External reference
Clinical responses to subgingival placement of a metronidazole 25% gel compared to the effect of subgingival scaling in adult periodontitis
10.1111/j.1600-051x.1992.tb02535.x · 1992 · External reference
Local application of metronidazole dental gel
1995 · External reference
Sustained local delivery of chlorhexidine in the treatment of periodontitis: a multi-center study
10.1902/jop.1997.68.1.32 · 1997 · External reference
Adjunctive use of a subgingival controlled-release chlorhexidine chip reduces probing depth and improves attachment level compared with scaling and root planing alone
10.1902/jop.1998.69.9.989 · 1998 · External reference
Comparison of 3 periodontal local antibiotic therapies in persistent periodontal pockets
10.1902/jop.1996.67.9.860 · 1996 · External reference
A six-month comparison of three periodontal local antimicrobial therapies in persistent periodontal pockets
10.1902/jop.1999.70.1.1 · 1999 · External reference
Local versus systemic adjunctive antibiotic therapy in RPP patients
1995 · External reference
Radiographic and BANA test analysis of locally delivered metronidazole: a phase I/II clinical trial
1994 · External reference
A clinical and microbiological evaluation of systemic and local metronidazole delivery in adult periodontitis patients
10.1111/j.1600-051x.1997.tb00485.x · 1997 · External reference
Clinical response to local delivery of tetracycline in relation to overall and local periodontal conditions
10.1111/j.1600-051x.1997.tb00214.x · 1997 · External reference
