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References from Polyol pathway and diabetic nephropathy revisited: Early tubular cell changes and glomerulopathy in diabetic mice overexpressing human aldose reductase. Local targets link to admitted publications; unresolved targets remain external evidence.
Sorbitol, phosphoinositides, and sodium-potassium-ATPase in the pathogenesis of diabetic complications
10.1056/nejm198703053161007 · 1987 · External reference
The involvement of aldose reductase in diabetic complications
10.1002/dmr.5610040403 · 1988 · External reference
The link between hyperglycaemia and diabetic nephropathy
10.1007/bf00400475 · 1992 · External reference
Mechanisms of glucose-enhanced extracellular matrix accumulation in rat glomerular mesangial cells
10.2337/diabetes.43.3.478 · 1994 · External reference
Aldose reductase regulates tgf-beta1-induced production of fibronectin and type iv collagen in cultured rat mesangial cells
10.1111/j.1440-1797.2006.00553.x · 2006 · External reference
Effects of polyol-pathway inhibition and dietary myo-inositol on glomerular hemodynamic function in experimental diabetes mellitus in rats
10.2337/diabetes.40.4.465 · 1991 · External reference
Zopolrestat prevention of proteinuria, albuminuria and cataractogenesis in diabetes mellitus
10.1159/000139394 · 1996 · External reference
Effects of sorbinil on glomerular structure and function in long-term-diabetic rats
10.2337/diabetes.38.7.839 · 1989 · External reference
Reduction of glomerular hyperfiltration in normoalbuminuric IDDM patients by 6 mo of aldose reductase inhibition
10.2337/diabetes.40.5.527 · 1991 · External reference
Z-2 microsatellite allele is linked to increased expression of the aldose reductase gene in diabetic nephropathy
10.1210/jc.83.8.2886 · 1998 · External reference
Crucial role of aldose reductase activity and plasma glucose level in sorbitol accumulation in erythrocytes from diabetic patients
10.2337/diabetes.40.10.1233 · 1991 · External reference
Diabetic nephropathy is not associated with the dinucleotide repeat polymorphism upstream of the aldose reductase (alr2) gene but with erythrocyte aldose reductase content in Japanese subjects with type 2 diabetes
10.2337/diabetes.48.2.420 · 1999 · External reference
Unresolved reference
1995 · External reference
Acute onset of diabetic pathological changes in transgenic mice with human aldose reductase cDNA
10.1007/bf00400627 · 1995 · External reference
Galactosemic neuropathy in transgenic mice for human aldose reductase
10.2337/diabetes.45.1.56 · 1996 · External reference
Effects of polyol pathway hyperactivity on protein kinase c activity, nociceptive peptide expression, and neuronal structure in dorsal root ganglia in diabetic mice
10.2337/diabetes.53.12.3239 · 2004 · External reference
Central role for aldose reductase pathway in myocardial ischemic injury
10.1096/fj.03-1400com · 2004 · External reference
Aldose reductase inhibitors improve myocardial reperfusion injury in mice by a dual mechanism
10.1254/jphs.fp0060218 · 2006 · External reference
Purification and characterization of the recombinant human aldose reductase expressed in baculovirus system
10.1016/0167-4838(91)99006-e · 1991 · External reference
Unresolved reference
1986 · External reference
Morphometric detection of incipient glomerular lesions in diabetic nephropathy in rats. Protective effects of ace inhibition
1995 · External reference
Determination of membrane thickness distribution from orthogonal intercepts
10.1111/j.1365-2818.1979.tb00149.x · 1979 · External reference
Localization of aldose and aldehyde reductase in the kidney
10.1038/ki.1989.270 · 1989 · External reference
Hydration status affects nuclear distribution of transcription factor tonicity responsive enhancer binding protein in rat kidney
10.1681/asn.v12112221 · 2001 · External reference
Peroxynitrite induces formation of n(ε)-(carboxymethyl) lysine by the cleavage of amadori product and generation of glucosone and glyoxal from glucose: Novel pathways for protein modification by peroxynitrite
10.2337/diabetes.51.9.2833 · 2002 · External reference
Expression of osmotic stress-related genes in tissues of normal and hyposmotic rats
10.1152/ajprenal.00028.2003 · 2003 · External reference
Tubular changes in early diabetic nephropathy
10.1053/j.ackd.2005.01.008 · 2005 · External reference
ORE, a eukaryotic minimal essential osmotic response element. The aldose reductase gene in hyperosmotic stress
10.1074/jbc.271.31.18318 · 1996 · External reference
Regulation of tonEBP transcriptional activator in mdck cells following changes in ambient tonicity
10.1152/ajpcell.00216.2002 · 2002 · External reference
The relative roles of advanced glycation, oxidation and aldose reductase inhibition in the development of experimental diabetic nephropathy in the Sprague-Dawley rat
10.1007/bf00410275 · 1995 · External reference
Role of oxidative stress in diabetic complications: A new perspective on an old paradigm
10.2337/diabetes.48.1.1 · 1999 · External reference
Hyperglycemic pseudohypoxia and diabetic complications
10.2337/diabetes.42.6.801 · 1993 · External reference
Prevention of hemodynamic and vascular albumin filtration changes in diabetic rats by aldose reductase inhibitors
10.2337/diabetes.38.10.1258 · 1989 · External reference
Increased endothelial albumin permeability mediated by protein kinase c activation
10.1172/jci114663 · 1990 · External reference
Protein kinase C activation and the development of diabetic complications
10.2337/diabetes.47.6.859 · 1998 · External reference
Increased expression of endothelial cell nitric oxide synthase (ecNOS) in afferent and glomerular endothelial cells is involved in glomerular hyperfiltration of diabetic nephropathy
10.1007/s001250051088 · 1998 · External reference
Expression of nitric oxide synthase in macula densa in streptozotocin diabetic rats
10.1007/s001250050512 · 1996 · External reference
Diabetic-like retinopathy ameliorated with the aldose reductase inhibitor way-121,509
1996 · External reference
Effect of aldose reductase inhibition and insulin treatment on retinal capillary basement membrane thickening in bb rats
10.2337/diabetes.38.9.1181 · 1989 · External reference
The case for intrarenal hypertension in the initiation and progression of diabetic and other glomerulopathies
10.1016/0002-9343(82)90490-9 · 1982 · External reference
TAGE (toxic ages) theory in diabetic complications
10.2174/156652406776894536 · 2006 · External reference
Immunohistochemical evidence for an increased oxidative stress and carbonyl modification of proteins in diabetic glomerular lesions
10.1681/asn.v104822 · 1999 · External reference
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy
10.1172/jci119853 · 1997 · External reference